"methotrexate" meaning in English

See methotrexate in All languages combined, or Wiktionary

Noun

IPA: /ˌmɛθ.əˈtɹɛk.seɪt/ [Received-Pronunciation], /ˌmiː.θəˈtɹɛk.seɪt/ [Received-Pronunciation], /ˌmɛθ.əˈtɹɛkˌseɪt/ [General-American] Forms: methotrexates [plural], MTX [abbreviation]
Etymology: Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate. Etymology templates: {{af|en|metho-|pteridine|carboxylate|alt2=tre-|alt3=(carbo)x(yl)ate|t2=alteration of pteridine}} metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate Head templates: {{en-noun|~}} methotrexate (countable and uncountable, plural methotrexates)
  1. (pharmacology) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies. Wikipedia link: methotrexate Tags: countable, uncountable Categories (topical): Pharmaceutical drugs Synonyms: amethopterin Derived forms: -trexate (english: folic acid analog) Translations (antimetabolite and antifolate drug): méthotrexate [masculine] (French), Methotrexat [neuter] (German), metotrexát (Hungarian), metotrexato [masculine] (Italian), метотрексат (metotreksat) (Kazakh), metotrexato [masculine] (Spanish)

Inflected forms

Alternative forms

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      "expansion": "metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate",
      "name": "af"
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  "etymology_text": "Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate.",
  "forms": [
    {
      "form": "methotrexates",
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  "lang_code": "en",
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      ],
      "derived": [
        {
          "english": "folic acid analog",
          "word": "-trexate"
        }
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        {
          "ref": "2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate, published 2011, page 133:",
          "text": "One group would be treated with intensive methotrexate dosing, while the other group would be treated with milder and less intensive dosing.",
          "type": "quote"
        }
      ],
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        ],
        [
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        ],
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        ]
      ],
      "raw_glosses": [
        "(pharmacology) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies."
      ],
      "synonyms": [
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          "word": "amethopterin"
        }
      ],
      "tags": [
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      ],
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        "medicine",
        "pharmacology",
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      "translations": [
        {
          "code": "fr",
          "lang": "French",
          "sense": "antimetabolite and antifolate drug",
          "tags": [
            "masculine"
          ],
          "word": "méthotrexate"
        },
        {
          "code": "de",
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          "word": "Methotrexat"
        },
        {
          "code": "hu",
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          "sense": "antimetabolite and antifolate drug",
          "word": "metotrexát"
        },
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          "code": "it",
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          "sense": "antimetabolite and antifolate drug",
          "tags": [
            "masculine"
          ],
          "word": "metotrexato"
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          "sense": "antimetabolite and antifolate drug",
          "word": "метотрексат"
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          "sense": "antimetabolite and antifolate drug",
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          ],
          "word": "metotrexato"
        }
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      "ipa": "/ˌmiː.θəˈtɹɛk.seɪt/",
      "tags": [
        "Received-Pronunciation"
      ]
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        "General-American"
      ]
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  ],
  "word": "methotrexate"
}
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  "forms": [
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      "form": "methotrexates",
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      ]
    },
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        }
      ],
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          "antifolate"
        ],
        [
          "cancer",
          "cancer"
        ],
        [
          "autoimmune",
          "autoimmune"
        ],
        [
          "ectopic pregnancies",
          "ectopic pregnancy"
        ]
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      "raw_glosses": [
        "(pharmacology) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies."
      ],
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      "ipa": "/ˌmiː.θəˈtɹɛk.seɪt/",
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        "Received-Pronunciation"
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      "code": "fr",
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      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "masculine"
      ],
      "word": "méthotrexate"
    },
    {
      "code": "de",
      "lang": "German",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
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      ],
      "word": "Methotrexat"
    },
    {
      "code": "hu",
      "lang": "Hungarian",
      "sense": "antimetabolite and antifolate drug",
      "word": "metotrexát"
    },
    {
      "code": "it",
      "lang": "Italian",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "masculine"
      ],
      "word": "metotrexato"
    },
    {
      "code": "kk",
      "lang": "Kazakh",
      "roman": "metotreksat",
      "sense": "antimetabolite and antifolate drug",
      "word": "метотрексат"
    },
    {
      "code": "es",
      "lang": "Spanish",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "masculine"
      ],
      "word": "metotrexato"
    }
  ],
  "word": "methotrexate"
}

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This page is a part of the kaikki.org machine-readable English dictionary. This dictionary is based on structured data extracted on 2024-12-21 from the enwiktionary dump dated 2024-12-04 using wiktextract (d8cb2f3 and 4e554ae). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.