"methotrexate" meaning in All languages combined

See methotrexate on Wiktionary

Noun [English]

IPA: /ˌmɛθ.əˈtɹɛk.seɪt/ [Received-Pronunciation], /ˌmiː.θəˈtɹɛk.seɪt/ [Received-Pronunciation], /ˌmɛθ.əˈtɹɛkˌseɪt/ [General-American] Forms: methotrexates [plural], MTX [abbreviation]
Etymology: Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate. Etymology templates: {{af|en|metho-|pteridine|carboxylate|alt2=tre-|alt3=(carbo)x(yl)ate|t2=alteration of pteridine}} metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate Head templates: {{en-noun|~}} methotrexate (countable and uncountable, plural methotrexates)
  1. (pharmacology) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies. Wikipedia link: methotrexate Tags: countable, uncountable Categories (topical): Pharmaceutical drugs Synonyms: amethopterin Derived forms: -trexate (english: folic acid analog) Translations (antimetabolite and antifolate drug): méthotrexate [masculine] (French), Methotrexat [neuter] (German), metotrexát (Hungarian), metotrexato [masculine] (Italian), метотрексат (metotreksat) (Kazakh), metotrexato [masculine] (Spanish)

Inflected forms

Alternative forms

Download JSON data for methotrexate meaning in All languages combined (3.5kB)

{
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "metho-",
        "3": "pteridine",
        "4": "carboxylate",
        "alt2": "tre-",
        "alt3": "(carbo)x(yl)ate",
        "t2": "alteration of pteridine"
      },
      "expansion": "metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate",
      "name": "af"
    }
  ],
  "etymology_text": "Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate.",
  "forms": [
    {
      "form": "methotrexates",
      "tags": [
        "plural"
      ]
    },
    {
      "form": "MTX",
      "tags": [
        "abbreviation"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {
        "1": "~"
      },
      "expansion": "methotrexate (countable and uncountable, plural methotrexates)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [
            "Entries with incorrect language header",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English entries with language name categories using raw markup",
          "parents": [
            "Entries with language name categories using raw markup",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English terms prefixed with metho-",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English terms suffixed with -ate",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "topical",
          "langcode": "en",
          "name": "Pharmaceutical drugs",
          "orig": "en:Pharmaceutical drugs",
          "parents": [
            "Drugs",
            "Matter",
            "Pharmacology",
            "Chemistry",
            "Nature",
            "Biochemistry",
            "Medicine",
            "Sciences",
            "All topics",
            "Biology",
            "Fundamental"
          ],
          "source": "w"
        }
      ],
      "derived": [
        {
          "english": "folic acid analog",
          "word": "-trexate"
        }
      ],
      "examples": [
        {
          "ref": "2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 133",
          "text": "One group would be treated with intensive methotrexate dosing, while the other group would be treated with milder and less intensive dosing.",
          "type": "quotation"
        }
      ],
      "glosses": [
        "An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies."
      ],
      "id": "en-methotrexate-en-noun-4jj-lfE7",
      "links": [
        [
          "pharmacology",
          "pharmacology"
        ],
        [
          "antimetabolite",
          "antimetabolite"
        ],
        [
          "antifolate",
          "antifolate"
        ],
        [
          "cancer",
          "cancer"
        ],
        [
          "autoimmune",
          "autoimmune"
        ],
        [
          "ectopic pregnancies",
          "ectopic pregnancy"
        ]
      ],
      "raw_glosses": [
        "(pharmacology) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies."
      ],
      "synonyms": [
        {
          "word": "amethopterin"
        }
      ],
      "tags": [
        "countable",
        "uncountable"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ],
      "translations": [
        {
          "code": "fr",
          "lang": "French",
          "sense": "antimetabolite and antifolate drug",
          "tags": [
            "masculine"
          ],
          "word": "méthotrexate"
        },
        {
          "code": "de",
          "lang": "German",
          "sense": "antimetabolite and antifolate drug",
          "tags": [
            "neuter"
          ],
          "word": "Methotrexat"
        },
        {
          "code": "hu",
          "lang": "Hungarian",
          "sense": "antimetabolite and antifolate drug",
          "word": "metotrexát"
        },
        {
          "code": "it",
          "lang": "Italian",
          "sense": "antimetabolite and antifolate drug",
          "tags": [
            "masculine"
          ],
          "word": "metotrexato"
        },
        {
          "code": "kk",
          "lang": "Kazakh",
          "roman": "metotreksat",
          "sense": "antimetabolite and antifolate drug",
          "word": "метотрексат"
        },
        {
          "code": "es",
          "lang": "Spanish",
          "sense": "antimetabolite and antifolate drug",
          "tags": [
            "masculine"
          ],
          "word": "metotrexato"
        }
      ],
      "wikipedia": [
        "methotrexate"
      ]
    }
  ],
  "sounds": [
    {
      "ipa": "/ˌmɛθ.əˈtɹɛk.seɪt/",
      "tags": [
        "Received-Pronunciation"
      ]
    },
    {
      "ipa": "/ˌmiː.θəˈtɹɛk.seɪt/",
      "tags": [
        "Received-Pronunciation"
      ]
    },
    {
      "ipa": "/ˌmɛθ.əˈtɹɛkˌseɪt/",
      "tags": [
        "General-American"
      ]
    }
  ],
  "word": "methotrexate"
}
{
  "derived": [
    {
      "english": "folic acid analog",
      "word": "-trexate"
    }
  ],
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "metho-",
        "3": "pteridine",
        "4": "carboxylate",
        "alt2": "tre-",
        "alt3": "(carbo)x(yl)ate",
        "t2": "alteration of pteridine"
      },
      "expansion": "metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate",
      "name": "af"
    }
  ],
  "etymology_text": "Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate.",
  "forms": [
    {
      "form": "methotrexates",
      "tags": [
        "plural"
      ]
    },
    {
      "form": "MTX",
      "tags": [
        "abbreviation"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {
        "1": "~"
      },
      "expansion": "methotrexate (countable and uncountable, plural methotrexates)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        "English 4-syllable words",
        "English compound terms",
        "English countable nouns",
        "English entries with incorrect language header",
        "English entries with language name categories using raw markup",
        "English lemmas",
        "English nouns",
        "English terms prefixed with metho-",
        "English terms suffixed with -ate",
        "English terms with IPA pronunciation",
        "English terms with quotations",
        "English uncountable nouns",
        "en:Pharmaceutical drugs"
      ],
      "examples": [
        {
          "ref": "2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 133",
          "text": "One group would be treated with intensive methotrexate dosing, while the other group would be treated with milder and less intensive dosing.",
          "type": "quotation"
        }
      ],
      "glosses": [
        "An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies."
      ],
      "links": [
        [
          "pharmacology",
          "pharmacology"
        ],
        [
          "antimetabolite",
          "antimetabolite"
        ],
        [
          "antifolate",
          "antifolate"
        ],
        [
          "cancer",
          "cancer"
        ],
        [
          "autoimmune",
          "autoimmune"
        ],
        [
          "ectopic pregnancies",
          "ectopic pregnancy"
        ]
      ],
      "raw_glosses": [
        "(pharmacology) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies."
      ],
      "tags": [
        "countable",
        "uncountable"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ],
      "wikipedia": [
        "methotrexate"
      ]
    }
  ],
  "sounds": [
    {
      "ipa": "/ˌmɛθ.əˈtɹɛk.seɪt/",
      "tags": [
        "Received-Pronunciation"
      ]
    },
    {
      "ipa": "/ˌmiː.θəˈtɹɛk.seɪt/",
      "tags": [
        "Received-Pronunciation"
      ]
    },
    {
      "ipa": "/ˌmɛθ.əˈtɹɛkˌseɪt/",
      "tags": [
        "General-American"
      ]
    }
  ],
  "synonyms": [
    {
      "word": "amethopterin"
    }
  ],
  "translations": [
    {
      "code": "fr",
      "lang": "French",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "masculine"
      ],
      "word": "méthotrexate"
    },
    {
      "code": "de",
      "lang": "German",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "neuter"
      ],
      "word": "Methotrexat"
    },
    {
      "code": "hu",
      "lang": "Hungarian",
      "sense": "antimetabolite and antifolate drug",
      "word": "metotrexát"
    },
    {
      "code": "it",
      "lang": "Italian",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "masculine"
      ],
      "word": "metotrexato"
    },
    {
      "code": "kk",
      "lang": "Kazakh",
      "roman": "metotreksat",
      "sense": "antimetabolite and antifolate drug",
      "word": "метотрексат"
    },
    {
      "code": "es",
      "lang": "Spanish",
      "sense": "antimetabolite and antifolate drug",
      "tags": [
        "masculine"
      ],
      "word": "metotrexato"
    }
  ],
  "word": "methotrexate"
}

This page is a part of the kaikki.org machine-readable All languages combined dictionary. This dictionary is based on structured data extracted on 2024-05-24 from the enwiktionary dump dated 2024-05-02 using wiktextract (46b31b8 and c7ea76d). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.