"natural killer cell" meaning in English

See natural killer cell in All languages combined, or Wiktionary

Noun

Forms: natural killer cells [plural]
Etymology: The description "natural killer" refers to the fact that they do not require activation to kill cells missing MHC class I "self" markers. Head templates: {{en-noun}} natural killer cell (plural natural killer cells)
  1. (immunology) Any cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response as part of the innate immune system. Wikipedia link: MHC class I, natural killer cell Categories (topical): Immunology Synonyms: large granular lymphocyte, NK, NK cell Related terms: cytotoxic T cell (english: performs an analogous role for the adaptive immune system) Translations (cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response): természetes ölősejt (Hungarian), kujerexaneya sirûştî [feminine] (Northern Kurdish), doğal katil hücre (Turkish), doğal öldürücü hücre (Turkish)
    Sense id: en-natural_killer_cell-en-noun-tUgactsU Categories (other): English entries with incorrect language header Topics: immunology, medicine, sciences

Inflected forms

Download JSON data for natural killer cell meaning in English (3.5kB)

{
  "etymology_text": "The description \"natural killer\" refers to the fact that they do not require activation to kill cells missing MHC class I \"self\" markers.",
  "forms": [
    {
      "form": "natural killer cells",
      "tags": [
        "plural"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "natural killer cell (plural natural killer cells)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [
            "Entries with incorrect language header",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "topical",
          "langcode": "en",
          "name": "Immunology",
          "orig": "en:Immunology",
          "parents": [
            "Medicine",
            "Biology",
            "Sciences",
            "All topics",
            "Fundamental"
          ],
          "source": "w"
        }
      ],
      "examples": [
        {
          "ref": "1982, Gustavo Cudkowicz, “Regulation of Natural Cytotoxic Activity”, in Sigurd J. Normann, Ernst Sorkin, editors, Macrophages and Natural Killer Cells, Plenum Press, page 767",
          "text": "While such information doesn't assist us in deciding whether natural killer cells derive from a macrophage or T cell lineage, it does tell us that the mouse natural killer cell system is a thymus dependent system.",
          "type": "quotation"
        },
        {
          "text": "1984, Meir Kende, Joseph Gainer, Michael A. Chirigos (editors), Chemical Regulation of Immunity in Veterinary Medicine: Proceedings of a Symposium, A. R. Liss, page 138,\nNatural killer cell activity is currently an area of active interest in cellular immunology (Herberman 1981)."
        },
        {
          "ref": "1999, Toxicological Profile for Lead, United States Department of Health and Human Services, page 173",
          "text": "The effects of lead exposure of varying duration on natural killer cell and T-lymphocyte function were investigated in rats.",
          "type": "quotation"
        }
      ],
      "glosses": [
        "Any cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response as part of the innate immune system."
      ],
      "id": "en-natural_killer_cell-en-noun-tUgactsU",
      "links": [
        [
          "immunology",
          "immunology"
        ],
        [
          "cell",
          "cell"
        ],
        [
          "receptor",
          "receptor"
        ],
        [
          "signal",
          "signal"
        ],
        [
          "activate",
          "activate"
        ],
        [
          "inhibit",
          "inhibit"
        ],
        [
          "response",
          "response"
        ],
        [
          "innate immune system",
          "innate immune system"
        ]
      ],
      "raw_glosses": [
        "(immunology) Any cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response as part of the innate immune system."
      ],
      "related": [
        {
          "english": "performs an analogous role for the adaptive immune system",
          "word": "cytotoxic T cell"
        }
      ],
      "synonyms": [
        {
          "word": "large granular lymphocyte"
        },
        {
          "word": "NK"
        },
        {
          "word": "NK cell"
        }
      ],
      "topics": [
        "immunology",
        "medicine",
        "sciences"
      ],
      "translations": [
        {
          "code": "hu",
          "lang": "Hungarian",
          "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
          "word": "természetes ölősejt"
        },
        {
          "code": "kmr",
          "lang": "Northern Kurdish",
          "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
          "tags": [
            "feminine"
          ],
          "word": "kujerexaneya sirûştî"
        },
        {
          "code": "tr",
          "lang": "Turkish",
          "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
          "word": "doğal katil hücre"
        },
        {
          "code": "tr",
          "lang": "Turkish",
          "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
          "word": "doğal öldürücü hücre"
        }
      ],
      "wikipedia": [
        "MHC class I",
        "natural killer cell"
      ]
    }
  ],
  "word": "natural killer cell"
}
{
  "etymology_text": "The description \"natural killer\" refers to the fact that they do not require activation to kill cells missing MHC class I \"self\" markers.",
  "forms": [
    {
      "form": "natural killer cells",
      "tags": [
        "plural"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "natural killer cell (plural natural killer cells)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "related": [
    {
      "english": "performs an analogous role for the adaptive immune system",
      "word": "cytotoxic T cell"
    }
  ],
  "senses": [
    {
      "categories": [
        "English countable nouns",
        "English entries with incorrect language header",
        "English lemmas",
        "English multiword terms",
        "English nouns",
        "English terms with quotations",
        "Quotation templates to be cleaned",
        "en:Immunology"
      ],
      "examples": [
        {
          "ref": "1982, Gustavo Cudkowicz, “Regulation of Natural Cytotoxic Activity”, in Sigurd J. Normann, Ernst Sorkin, editors, Macrophages and Natural Killer Cells, Plenum Press, page 767",
          "text": "While such information doesn't assist us in deciding whether natural killer cells derive from a macrophage or T cell lineage, it does tell us that the mouse natural killer cell system is a thymus dependent system.",
          "type": "quotation"
        },
        {
          "text": "1984, Meir Kende, Joseph Gainer, Michael A. Chirigos (editors), Chemical Regulation of Immunity in Veterinary Medicine: Proceedings of a Symposium, A. R. Liss, page 138,\nNatural killer cell activity is currently an area of active interest in cellular immunology (Herberman 1981)."
        },
        {
          "ref": "1999, Toxicological Profile for Lead, United States Department of Health and Human Services, page 173",
          "text": "The effects of lead exposure of varying duration on natural killer cell and T-lymphocyte function were investigated in rats.",
          "type": "quotation"
        }
      ],
      "glosses": [
        "Any cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response as part of the innate immune system."
      ],
      "links": [
        [
          "immunology",
          "immunology"
        ],
        [
          "cell",
          "cell"
        ],
        [
          "receptor",
          "receptor"
        ],
        [
          "signal",
          "signal"
        ],
        [
          "activate",
          "activate"
        ],
        [
          "inhibit",
          "inhibit"
        ],
        [
          "response",
          "response"
        ],
        [
          "innate immune system",
          "innate immune system"
        ]
      ],
      "raw_glosses": [
        "(immunology) Any cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response as part of the innate immune system."
      ],
      "synonyms": [
        {
          "word": "large granular lymphocyte"
        },
        {
          "word": "NK"
        },
        {
          "word": "NK cell"
        }
      ],
      "topics": [
        "immunology",
        "medicine",
        "sciences"
      ],
      "wikipedia": [
        "MHC class I",
        "natural killer cell"
      ]
    }
  ],
  "translations": [
    {
      "code": "hu",
      "lang": "Hungarian",
      "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
      "word": "természetes ölősejt"
    },
    {
      "code": "kmr",
      "lang": "Northern Kurdish",
      "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
      "tags": [
        "feminine"
      ],
      "word": "kujerexaneya sirûştî"
    },
    {
      "code": "tr",
      "lang": "Turkish",
      "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
      "word": "doğal katil hücre"
    },
    {
      "code": "tr",
      "lang": "Turkish",
      "sense": "cell that expresses cell surface receptors that deliver signals to either activate or inhibit a response",
      "word": "doğal öldürücü hücre"
    }
  ],
  "word": "natural killer cell"
}

This page is a part of the kaikki.org machine-readable English dictionary. This dictionary is based on structured data extracted on 2024-05-03 from the enwiktionary dump dated 2024-05-02 using wiktextract (f4fd8c9 and c9440ce). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

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