"sildenafil" meaning in English

See sildenafil in All languages combined, or Wiktionary

Noun

IPA: /sɪlˈdɛn.ə.fɪl/ Forms: sildenafils [plural]
Etymology: Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl. Etymology templates: {{af|en|sulfonyl|pyrimidine|phenyl|alt1=s(ulfon)yl|alt2=-dena-|alt3=ph(en)yl|t2=alteration of (pyrimi)dine}} s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl Head templates: {{en-noun|-|s}} sildenafil (usually uncountable, plural sildenafils)
  1. (pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra. Wikipedia link: sildenafil Tags: uncountable, usually Categories (topical): Pharmaceutical drugs Derived forms: -afil, sildenafil citrate Translations (Translations): sildenafiili (Finnish)

Inflected forms

Download JSON data for sildenafil meaning in English (3.2kB)

{
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "sulfonyl",
        "3": "pyrimidine",
        "4": "phenyl",
        "alt1": "s(ulfon)yl",
        "alt2": "-dena-",
        "alt3": "ph(en)yl",
        "t2": "alteration of (pyrimi)dine"
      },
      "expansion": "s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl",
      "name": "af"
    }
  ],
  "etymology_text": "Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl.",
  "forms": [
    {
      "form": "sildenafils",
      "tags": [
        "plural"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {
        "1": "-",
        "2": "s"
      },
      "expansion": "sildenafil (usually uncountable, plural sildenafils)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [
            "Entries with incorrect language header",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English entries with language name categories using raw markup",
          "parents": [
            "Entries with language name categories using raw markup",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English terms suffixed with -afil",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "topical",
          "langcode": "en",
          "name": "Pharmaceutical drugs",
          "orig": "en:Pharmaceutical drugs",
          "parents": [
            "Drugs",
            "Matter",
            "Pharmacology",
            "Chemistry",
            "Nature",
            "Biochemistry",
            "Medicine",
            "Sciences",
            "All topics",
            "Biology",
            "Fundamental"
          ],
          "source": "w"
        }
      ],
      "derived": [
        {
          "word": "-afil"
        },
        {
          "word": "sildenafil citrate"
        }
      ],
      "examples": [
        {
          "ref": "2017, David Friend, The Naughty Nineties",
          "text": "Ellis opens a file from his stack. In 1991, he says, Pfizer wanted to test the safety of what came to be known as sildenafil.",
          "type": "quotation"
        }
      ],
      "glosses": [
        "A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
      "id": "en-sildenafil-en-noun-hwfLNKr8",
      "links": [
        [
          "pharmacology",
          "pharmacology"
        ],
        [
          "citrate",
          "citrate"
        ],
        [
          "erectile dysfunction",
          "erectile dysfunction"
        ],
        [
          "suppressing",
          "suppress"
        ],
        [
          "phosphodiesterase",
          "phosphodiesterase"
        ],
        [
          "inhibitory",
          "inhibitory"
        ],
        [
          "hormone",
          "hormone"
        ],
        [
          "muscular",
          "muscular"
        ],
        [
          "vascular",
          "vascular"
        ],
        [
          "erection",
          "erection"
        ],
        [
          "Viagra",
          "Viagra"
        ]
      ],
      "raw_glosses": [
        "(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
      "tags": [
        "uncountable",
        "usually"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ],
      "translations": [
        {
          "code": "fi",
          "lang": "Finnish",
          "sense": "Translations",
          "word": "sildenafiili"
        }
      ],
      "wikipedia": [
        "sildenafil"
      ]
    }
  ],
  "sounds": [
    {
      "ipa": "/sɪlˈdɛn.ə.fɪl/"
    }
  ],
  "word": "sildenafil"
}
{
  "derived": [
    {
      "word": "-afil"
    },
    {
      "word": "sildenafil citrate"
    }
  ],
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "sulfonyl",
        "3": "pyrimidine",
        "4": "phenyl",
        "alt1": "s(ulfon)yl",
        "alt2": "-dena-",
        "alt3": "ph(en)yl",
        "t2": "alteration of (pyrimi)dine"
      },
      "expansion": "s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl",
      "name": "af"
    }
  ],
  "etymology_text": "Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl.",
  "forms": [
    {
      "form": "sildenafils",
      "tags": [
        "plural"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {
        "1": "-",
        "2": "s"
      },
      "expansion": "sildenafil (usually uncountable, plural sildenafils)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        "English 4-syllable words",
        "English compound terms",
        "English countable nouns",
        "English entries with incorrect language header",
        "English entries with language name categories using raw markup",
        "English lemmas",
        "English nouns",
        "English terms suffixed with -afil",
        "English terms with IPA pronunciation",
        "English terms with quotations",
        "English uncountable nouns",
        "Quotation templates to be cleaned",
        "Translation table header lacks gloss",
        "en:Pharmaceutical drugs"
      ],
      "examples": [
        {
          "ref": "2017, David Friend, The Naughty Nineties",
          "text": "Ellis opens a file from his stack. In 1991, he says, Pfizer wanted to test the safety of what came to be known as sildenafil.",
          "type": "quotation"
        }
      ],
      "glosses": [
        "A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
      "links": [
        [
          "pharmacology",
          "pharmacology"
        ],
        [
          "citrate",
          "citrate"
        ],
        [
          "erectile dysfunction",
          "erectile dysfunction"
        ],
        [
          "suppressing",
          "suppress"
        ],
        [
          "phosphodiesterase",
          "phosphodiesterase"
        ],
        [
          "inhibitory",
          "inhibitory"
        ],
        [
          "hormone",
          "hormone"
        ],
        [
          "muscular",
          "muscular"
        ],
        [
          "vascular",
          "vascular"
        ],
        [
          "erection",
          "erection"
        ],
        [
          "Viagra",
          "Viagra"
        ]
      ],
      "raw_glosses": [
        "(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
      "tags": [
        "uncountable",
        "usually"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ],
      "wikipedia": [
        "sildenafil"
      ]
    }
  ],
  "sounds": [
    {
      "ipa": "/sɪlˈdɛn.ə.fɪl/"
    }
  ],
  "translations": [
    {
      "code": "fi",
      "lang": "Finnish",
      "sense": "Translations",
      "word": "sildenafiili"
    }
  ],
  "word": "sildenafil"
}

This page is a part of the kaikki.org machine-readable English dictionary. This dictionary is based on structured data extracted on 2024-06-04 from the enwiktionary dump dated 2024-05-02 using wiktextract (e9e0a99 and db5a844). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.