"sildenafil" meaning in English

See sildenafil in All languages combined, or Wiktionary

Noun

IPA: /sɪlˈdɛn.ə.fɪl/ Forms: sildenafils [plural]
Etymology: Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl. Etymology templates: {{af|en|sulfonyl|pyrimidine|phenyl|alt1=s(ulfon)yl|alt2=-dena-|alt3=ph(en)yl|t2=alteration of (pyrimi)dine}} s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl Head templates: {{en-noun|-|s}} sildenafil (usually uncountable, plural sildenafils)
  1. (pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra. Wikipedia link: sildenafil Tags: uncountable, usually Categories (topical): Pharmaceutical drugs Derived forms: -afil, sildenafil citrate Translations (Translations): sildenafiili (Finnish)

Inflected forms

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        "alt3": "ph(en)yl",
        "t2": "alteration of (pyrimi)dine"
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      "name": "af"
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  "etymology_text": "Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl.",
  "forms": [
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  "lang_code": "en",
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  "senses": [
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          "name": "English entries with incorrect language header",
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        {
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      ],
      "examples": [
        {
          "ref": "2017, David Friend, The Naughty Nineties:",
          "text": "Ellis opens a file from his stack. In 1991, he says, Pfizer wanted to test the safety of what came to be known as sildenafil.",
          "type": "quote"
        }
      ],
      "glosses": [
        "A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
      "id": "en-sildenafil-en-noun-hwfLNKr8",
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      "raw_glosses": [
        "(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
      "tags": [
        "uncountable",
        "usually"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ],
      "translations": [
        {
          "code": "fi",
          "lang": "Finnish",
          "sense": "Translations",
          "word": "sildenafiili"
        }
      ],
      "wikipedia": [
        "sildenafil"
      ]
    }
  ],
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    {
      "ipa": "/sɪlˈdɛn.ə.fɪl/"
    }
  ],
  "word": "sildenafil"
}
{
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    {
      "word": "sildenafil citrate"
    }
  ],
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  "forms": [
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        "English uncountable nouns",
        "Entries with translation boxes",
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        "Quotation templates to be cleaned",
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        "en:Pharmaceutical drugs"
      ],
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        {
          "ref": "2017, David Friend, The Naughty Nineties:",
          "text": "Ellis opens a file from his stack. In 1991, he says, Pfizer wanted to test the safety of what came to be known as sildenafil.",
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      ],
      "glosses": [
        "A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
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        ],
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        ],
        [
          "erectile dysfunction",
          "erectile dysfunction"
        ],
        [
          "suppressing",
          "suppress"
        ],
        [
          "phosphodiesterase",
          "phosphodiesterase"
        ],
        [
          "inhibitory",
          "inhibitory"
        ],
        [
          "hormone",
          "hormone"
        ],
        [
          "muscular",
          "muscular"
        ],
        [
          "vascular",
          "vascular"
        ],
        [
          "erection",
          "erection"
        ],
        [
          "Viagra",
          "Viagra"
        ]
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      "raw_glosses": [
        "(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra."
      ],
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      ],
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      ]
    }
  ],
  "sounds": [
    {
      "ipa": "/sɪlˈdɛn.ə.fɪl/"
    }
  ],
  "translations": [
    {
      "code": "fi",
      "lang": "Finnish",
      "sense": "Translations",
      "word": "sildenafiili"
    }
  ],
  "word": "sildenafil"
}

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This page is a part of the kaikki.org machine-readable English dictionary. This dictionary is based on structured data extracted on 2025-01-20 from the enwiktionary dump dated 2025-01-01 using wiktextract (ee63ee9 and 4230888). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.