"lead hopping" meaning in English

{
  "head_templates": [
    {
      "args": {
        "1": "-"
      },
      "expansion": "lead hopping (uncountable)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [
            "Entries with incorrect language header",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "topical",
          "langcode": "en",
          "name": "Pharmacology",
          "orig": "en:Pharmacology",
          "parents": [
            "Biochemistry",
            "Medicine",
            "Biology",
            "Chemistry",
            "Sciences",
            "All topics",
            "Fundamental"
          ],
          "source": "w"
        }
      ],
      "glosses": [
        "the identification of isofunctional molecular structures with significantly different molecular backbones"
      ],
      "id": "en-lead_hopping-en-noun-L1bpgMHp",
      "links": [
        [
          "pharmacology",
          "pharmacology"
        ],
        [
          "isofunctional",
          "isofunctional"
        ],
        [
          "molecular",
          "molecular"
        ],
        [
          "structure",
          "structure"
        ],
        [
          "backbone",
          "backbone"
        ]
      ],
      "raw_glosses": [
        "(pharmacology) the identification of isofunctional molecular structures with significantly different molecular backbones"
      ],
      "synonyms": [
        {
          "word": "scaffold hopping"
        }
      ],
      "tags": [
        "uncountable"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ]
    }
  ],
  "word": "lead hopping"
}

{
  "head_templates": [
    {
      "args": {
        "1": "-"
      },
      "expansion": "lead hopping (uncountable)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        "English entries with incorrect language header",
        "English lemmas",
        "English multiword terms",
        "English nouns",
        "English uncountable nouns",
        "en:Pharmacology"
      ],
      "glosses": [
        "the identification of isofunctional molecular structures with significantly different molecular backbones"
      ],
      "links": [
        [
          "pharmacology",
          "pharmacology"
        ],
        [
          "isofunctional",
          "isofunctional"
        ],
        [
          "molecular",
          "molecular"
        ],
        [
          "structure",
          "structure"
        ],
        [
          "backbone",
          "backbone"
        ]
      ],
      "raw_glosses": [
        "(pharmacology) the identification of isofunctional molecular structures with significantly different molecular backbones"
      ],
      "tags": [
        "uncountable"
      ],
      "topics": [
        "medicine",
        "pharmacology",
        "sciences"
      ]
    }
  ],
  "synonyms": [
    {
      "word": "scaffold hopping"
    }
  ],
  "word": "lead hopping"
}