"Lipinski's rule of five" meaning in English

{
  "etymology_text": "The rule was formulated by Christopher A. Lipinski in 1997. Five refers to the multiples of five that occur in all of the criteria.",
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      "glosses": [
        "A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5."
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        "(chemistry) A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5."
      ],
      "synonyms": [
        {
          "word": "Pfizer's rule of five"
        },
        {
          "word": "RO5"
        },
        {
          "word": "rule of five"
        }
      ],
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{
  "etymology_text": "The rule was formulated by Christopher A. Lipinski in 1997. Five refers to the multiples of five that occur in all of the criteria.",
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      "glosses": [
        "A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5."
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      "raw_glosses": [
        "(chemistry) A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5."
      ],
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          "word": "Pfizer's rule of five"
        },
        {
          "word": "RO5"
        },
        {
          "word": "rule of five"
        }
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  "word": "Lipinski's rule of five"
}