"run its course" meaning in English

{
  "forms": [
    {
      "form": "runs its course",
      "tags": [
        "present",
        "singular",
        "third-person"
      ]
    },
    {
      "form": "running its course",
      "tags": [
        "participle",
        "present"
      ]
    },
    {
      "form": "ran its course",
      "tags": [
        "past"
      ]
    },
    {
      "form": "run its course",
      "tags": [
        "participle",
        "past"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {
        "1": "run<,,ran,run> its course"
      },
      "expansion": "run its course (third-person singular simple present runs its course, present participle running its course, simple past ran its course, past participle run its course)",
      "name": "en-verb"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "verb",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [
            "Entries with incorrect language header",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English terms with placeholder \"it\"",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Entries with translation boxes",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Pages with 1 entry",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Pages with entries",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Terms with Dutch translations",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Terms with Finnish translations",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Terms with Italian translations",
          "parents": [],
          "source": "w"
        }
      ],
      "glosses": [
        "To come to a natural end."
      ],
      "id": "en-run_its_course-en-verb-zt~2DtJk",
      "links": [
        [
          "end",
          "end"
        ]
      ],
      "synonyms": [
        {
          "word": "take its course"
        }
      ],
      "translations": [
        {
          "code": "nl",
          "lang": "Dutch",
          "sense": "Translations",
          "word": "zijn gang gaan"
        },
        {
          "code": "fi",
          "lang": "Finnish",
          "sense": "Translations",
          "word": "tulla tiensä päähän"
        },
        {
          "code": "it",
          "lang": "Italian",
          "sense": "Translations",
          "word": "fare il suo corso"
        }
      ]
    }
  ],
  "sounds": [
    {
      "audio": "En-au-run its course.ogg",
      "mp3_url": "https://upload.wikimedia.org/wikipedia/commons/transcoded/9/93/En-au-run_its_course.ogg/En-au-run_its_course.ogg.mp3",
      "ogg_url": "https://upload.wikimedia.org/wikipedia/commons/9/93/En-au-run_its_course.ogg"
    }
  ],
  "word": "run its course"
}

{
  "forms": [
    {
      "form": "runs its course",
      "tags": [
        "present",
        "singular",
        "third-person"
      ]
    },
    {
      "form": "running its course",
      "tags": [
        "participle",
        "present"
      ]
    },
    {
      "form": "ran its course",
      "tags": [
        "past"
      ]
    },
    {
      "form": "run its course",
      "tags": [
        "participle",
        "past"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {
        "1": "run<,,ran,run> its course"
      },
      "expansion": "run its course (third-person singular simple present runs its course, present participle running its course, simple past ran its course, past participle run its course)",
      "name": "en-verb"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "verb",
  "senses": [
    {
      "categories": [
        "English entries with incorrect language header",
        "English lemmas",
        "English multiword terms",
        "English terms with placeholder \"it\"",
        "English verbs",
        "Entries with translation boxes",
        "Pages with 1 entry",
        "Pages with entries",
        "Terms with Dutch translations",
        "Terms with Finnish translations",
        "Terms with Italian translations",
        "Translation table header lacks gloss"
      ],
      "glosses": [
        "To come to a natural end."
      ],
      "links": [
        [
          "end",
          "end"
        ]
      ],
      "synonyms": [
        {
          "word": "take its course"
        }
      ]
    }
  ],
  "sounds": [
    {
      "audio": "En-au-run its course.ogg",
      "mp3_url": "https://upload.wikimedia.org/wikipedia/commons/transcoded/9/93/En-au-run_its_course.ogg/En-au-run_its_course.ogg.mp3",
      "ogg_url": "https://upload.wikimedia.org/wikipedia/commons/9/93/En-au-run_its_course.ogg"
    }
  ],
  "translations": [
    {
      "code": "nl",
      "lang": "Dutch",
      "sense": "Translations",
      "word": "zijn gang gaan"
    },
    {
      "code": "fi",
      "lang": "Finnish",
      "sense": "Translations",
      "word": "tulla tiensä päähän"
    },
    {
      "code": "it",
      "lang": "Italian",
      "sense": "Translations",
      "word": "fare il suo corso"
    }
  ],
  "word": "run its course"
}