"citrullinate" meaning in English

{
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        "2": "citrulline",
        "3": "ate"
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      "expansion": "citrulline + -ate",
      "name": "suffix"
    }
  ],
  "etymology_text": "citrulline + -ate.",
  "forms": [
    {
      "form": "citrullinates",
      "tags": [
        "present",
        "singular",
        "third-person"
      ]
    },
    {
      "form": "citrullinating",
      "tags": [
        "participle",
        "present"
      ]
    },
    {
      "form": "citrullinated",
      "tags": [
        "participle",
        "past"
      ]
    },
    {
      "form": "citrullinated",
      "tags": [
        "past"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "citrullinate (third-person singular simple present citrullinates, present participle citrullinating, simple past and past participle citrullinated)",
      "name": "en-verb"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "verb",
  "senses": [
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        {
          "kind": "other",
          "name": "English entries with incorrect language header",
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          "name": "English terms suffixed with -ate",
          "parents": [],
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        },
        {
          "kind": "topical",
          "langcode": "en",
          "name": "Biochemistry",
          "orig": "en:Biochemistry",
          "parents": [
            "Biology",
            "Chemistry",
            "Sciences",
            "All topics",
            "Fundamental"
          ],
          "source": "w"
        }
      ],
      "examples": [
        {
          "ref": "2015 August 29, Stefan Reichert et al., “Association of levels of antibodies against citrullinated cyclic peptides and citrullinated α-enolase in chronic and aggressive periodontitis as a risk factor of Rheumatoid arthritis: a case control study”, in Journal of Translational Medicine, volume 13, →DOI",
          "text": "It has been shown that PPAD is able to citrullinate bacterial as well as host peptides such as fibrinogen and α-enolase.",
          "type": "quotation"
        },
        {
          "ref": "2017, E. E. Witalison, L. J. Hofseth, “22: Citrullination in Inflammatory-Driven Carcinogenesis of the Colon”, in Anthony P. Nicholas, Sanjoy K. Bhattacharya, Paul R. Thompson, editors, Protein Deimination in Human Health and Disease, 2nd edition, Springer, page 433",
          "text": "PADs do not typically citrullinate total arginines found in the amino acid sequence of a protein, but certain arginines are more susceptible to citrullination.[…]Likewise, PAD2 also citrullinates actin and myelin basic protein in the CNS, while PAD4 can citrullinate substrates like nucleophosmin, nuclear lamin C, and p21 (Lamensa and Moscarello 1993; Hagiwara et al. 2002; Tanikawa et al. 2012; Li et al. 2008).",
          "type": "quotation"
        },
        {
          "ref": "2020, Burkhard Möller, Florian Kollert, Anton Sculean, Peter M. Villiger, “79: Infectious Trigger in Periodontitis and the Gut in Rheumatoid Arthritis (RA)”, in Erminia Mariani, Mariagrazia Uguccioni, Daniela Frasca, editors, Immunobiology of Osteoarticular Diseases, Frontiers Media, page 83",
          "text": "Furthermore, PPAD in contrast to human PAD is capable of citrullinating C-terminal arginine residues, which are generated by another Pg.-derived enzyme, arginine specific gingipain (Rgp) protease (81).",
          "type": "quotation"
        }
      ],
      "glosses": [
        "To react with, or convert to, citrulline."
      ],
      "id": "en-citrullinate-en-verb-p7h9x6rC",
      "links": [
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          "biochemistry",
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        [
          "citrulline",
          "citrulline"
        ]
      ],
      "raw_glosses": [
        "(biochemistry, transitive) To react with, or convert to, citrulline."
      ],
      "tags": [
        "transitive"
      ],
      "topics": [
        "biochemistry",
        "biology",
        "chemistry",
        "microbiology",
        "natural-sciences",
        "physical-sciences"
      ]
    }
  ],
  "word": "citrullinate"
}

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        "2": "citrulline",
        "3": "ate"
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      "expansion": "citrulline + -ate",
      "name": "suffix"
    }
  ],
  "etymology_text": "citrulline + -ate.",
  "forms": [
    {
      "form": "citrullinates",
      "tags": [
        "present",
        "singular",
        "third-person"
      ]
    },
    {
      "form": "citrullinating",
      "tags": [
        "participle",
        "present"
      ]
    },
    {
      "form": "citrullinated",
      "tags": [
        "participle",
        "past"
      ]
    },
    {
      "form": "citrullinated",
      "tags": [
        "past"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "citrullinate (third-person singular simple present citrullinates, present participle citrullinating, simple past and past participle citrullinated)",
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  "lang": "English",
  "lang_code": "en",
  "pos": "verb",
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      "examples": [
        {
          "ref": "2015 August 29, Stefan Reichert et al., “Association of levels of antibodies against citrullinated cyclic peptides and citrullinated α-enolase in chronic and aggressive periodontitis as a risk factor of Rheumatoid arthritis: a case control study”, in Journal of Translational Medicine, volume 13, →DOI",
          "text": "It has been shown that PPAD is able to citrullinate bacterial as well as host peptides such as fibrinogen and α-enolase.",
          "type": "quotation"
        },
        {
          "ref": "2017, E. E. Witalison, L. J. Hofseth, “22: Citrullination in Inflammatory-Driven Carcinogenesis of the Colon”, in Anthony P. Nicholas, Sanjoy K. Bhattacharya, Paul R. Thompson, editors, Protein Deimination in Human Health and Disease, 2nd edition, Springer, page 433",
          "text": "PADs do not typically citrullinate total arginines found in the amino acid sequence of a protein, but certain arginines are more susceptible to citrullination.[…]Likewise, PAD2 also citrullinates actin and myelin basic protein in the CNS, while PAD4 can citrullinate substrates like nucleophosmin, nuclear lamin C, and p21 (Lamensa and Moscarello 1993; Hagiwara et al. 2002; Tanikawa et al. 2012; Li et al. 2008).",
          "type": "quotation"
        },
        {
          "ref": "2020, Burkhard Möller, Florian Kollert, Anton Sculean, Peter M. Villiger, “79: Infectious Trigger in Periodontitis and the Gut in Rheumatoid Arthritis (RA)”, in Erminia Mariani, Mariagrazia Uguccioni, Daniela Frasca, editors, Immunobiology of Osteoarticular Diseases, Frontiers Media, page 83",
          "text": "Furthermore, PPAD in contrast to human PAD is capable of citrullinating C-terminal arginine residues, which are generated by another Pg.-derived enzyme, arginine specific gingipain (Rgp) protease (81).",
          "type": "quotation"
        }
      ],
      "glosses": [
        "To react with, or convert to, citrulline."
      ],
      "links": [
        [
          "biochemistry",
          "biochemistry"
        ],
        [
          "citrulline",
          "citrulline"
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      "raw_glosses": [
        "(biochemistry, transitive) To react with, or convert to, citrulline."
      ],
      "tags": [
        "transitive"
      ],
      "topics": [
        "biochemistry",
        "biology",
        "chemistry",
        "microbiology",
        "natural-sciences",
        "physical-sciences"
      ]
    }
  ],
  "word": "citrullinate"
}