"original antigenic sin" meaning in All languages combined

See original antigenic sin on Wiktionary

Noun [English]

Etymology: See original sin. Etymology templates: {{m|en|original sin}} original sin Head templates: {{en-noun|-}} original antigenic sin (uncountable)
  1. (immunology) The propensity of the immune system to preferentially use immunological memory based on a previous infection when a second, slightly different version of the foreign pathogen is encountered, leaving the immune system "trapped" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections. Tags: uncountable Categories (topical): Immunology Synonyms: Hoskins effect [initialism], OAS
    Sense id: en-original_antigenic_sin-en-noun-OYpPBykA Categories (other): English entries with incorrect language header Topics: immunology, medicine, sciences

Alternative forms

Download JSON data for original antigenic sin meaning in All languages combined (2.0kB)

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  "etymology_text": "See original sin.",
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  "lang_code": "en",
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        "The propensity of the immune system to preferentially use immunological memory based on a previous infection when a second, slightly different version of the foreign pathogen is encountered, leaving the immune system \"trapped\" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections."
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      "raw_glosses": [
        "(immunology) The propensity of the immune system to preferentially use immunological memory based on a previous infection when a second, slightly different version of the foreign pathogen is encountered, leaving the immune system \"trapped\" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections."
      ],
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          "word": "Hoskins effect"
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  "etymology_text": "See original sin.",
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        "(immunology) The propensity of the immune system to preferentially use immunological memory based on a previous infection when a second, slightly different version of the foreign pathogen is encountered, leaving the immune system \"trapped\" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections."
      ],
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          "word": "Hoskins effect"
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      "topics": [
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  "word": "original antigenic sin"
}

This page is a part of the kaikki.org machine-readable All languages combined dictionary. This dictionary is based on structured data extracted on 2024-05-09 from the enwiktionary dump dated 2024-05-02 using wiktextract (4d5d0bb and edd475d). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.