See VEXAS on Wiktionary
{ "etymology_text": "First discovered in October 2020, with the report from The New England Journal of Medicine and identified by a multidisciplinary team of scientists (see quotations below).", "head_templates": [ { "args": { "1": "-" }, "expansion": "VEXAS (uncountable)", "name": "en-noun" } ], "lang": "English", "lang_code": "en", "pos": "noun", "senses": [ { "categories": [ { "kind": "other", "name": "English entries with incorrect language header", "parents": [ "Entries with incorrect language header", "Entry maintenance" ], "source": "w" }, { "kind": "other", "name": "Pages with 1 entry", "parents": [], "source": "w" }, { "kind": "other", "name": "Pages with entries", "parents": [], "source": "w" }, { "kind": "topical", "langcode": "en", "name": "Biology", "orig": "en:Biology", "parents": [ "Sciences", "All topics", "Fundamental" ], "source": "w" }, { "kind": "topical", "langcode": "en", "name": "Medicine", "orig": "en:Medicine", "parents": [ "Biology", "Healthcare", "Sciences", "Health", "All topics", "Body", "Fundamental" ], "source": "w" } ], "examples": [ { "ref": "2020 October 27, David B. Beck, Marcela A. Ferrada, Keith A. Sikora, Amanda K. Ombrello, et alia, “Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease”, in New England Journal of Medicine, volume 383, →DOI:", "text": "Using a genotype-driven approach, we identified a disorder that connects seemingly unrelated adult-onset inflammatory syndromes. We named this genetic disorder the VEXAS syndrome, which is caused by myeloid-restricted somatic missense mutations in UBA1.", "type": "quote" }, { "ref": "2021 July 1, Peter C. Grayson, Bhavisha A. Patel, Neal S. Young, “VEXAS syndrome”, in Blood, volume 137, number 26, →DOI, page 3591:", "text": "Additionally, patients with VEXAS suffer from a spectrum of hematologic problems, including macrocytic anemia, thrombocytopenia, thromboembolic disease, and progressive bone marrow failure, which can evolve to hematologic malignancy", "type": "quote" }, { "ref": "2023 February 14, Vicki Contie, “VEXAS syndrome more common than realized”, in National Institutes of Health:", "text": "The researchers note that a diagnosis based on symptoms alone could easily miss cases of VEXAS that would be caught by UBA1 testing.", "type": "quote" } ], "glosses": [ "An autoimmune disease that causes inflammation in the body and mostly affects men." ], "id": "en-VEXAS-en-noun-CH1WzPZ-", "links": [ [ "medicine", "medicine" ], [ "biology", "biology" ] ], "raw_glosses": [ "(medicine, biology) An autoimmune disease that causes inflammation in the body and mostly affects men." ], "tags": [ "uncountable" ], "topics": [ "biology", "medicine", "natural-sciences", "sciences" ] } ], "word": "VEXAS" }
{ "etymology_text": "First discovered in October 2020, with the report from The New England Journal of Medicine and identified by a multidisciplinary team of scientists (see quotations below).", "head_templates": [ { "args": { "1": "-" }, "expansion": "VEXAS (uncountable)", "name": "en-noun" } ], "lang": "English", "lang_code": "en", "pos": "noun", "senses": [ { "categories": [ "English entries with incorrect language header", "English lemmas", "English nouns", "English terms with quotations", "English uncountable nouns", "Pages with 1 entry", "Pages with entries", "en:Biology", "en:Medicine" ], "examples": [ { "ref": "2020 October 27, David B. Beck, Marcela A. Ferrada, Keith A. Sikora, Amanda K. Ombrello, et alia, “Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease”, in New England Journal of Medicine, volume 383, →DOI:", "text": "Using a genotype-driven approach, we identified a disorder that connects seemingly unrelated adult-onset inflammatory syndromes. We named this genetic disorder the VEXAS syndrome, which is caused by myeloid-restricted somatic missense mutations in UBA1.", "type": "quote" }, { "ref": "2021 July 1, Peter C. Grayson, Bhavisha A. Patel, Neal S. Young, “VEXAS syndrome”, in Blood, volume 137, number 26, →DOI, page 3591:", "text": "Additionally, patients with VEXAS suffer from a spectrum of hematologic problems, including macrocytic anemia, thrombocytopenia, thromboembolic disease, and progressive bone marrow failure, which can evolve to hematologic malignancy", "type": "quote" }, { "ref": "2023 February 14, Vicki Contie, “VEXAS syndrome more common than realized”, in National Institutes of Health:", "text": "The researchers note that a diagnosis based on symptoms alone could easily miss cases of VEXAS that would be caught by UBA1 testing.", "type": "quote" } ], "glosses": [ "An autoimmune disease that causes inflammation in the body and mostly affects men." ], "links": [ [ "medicine", "medicine" ], [ "biology", "biology" ] ], "raw_glosses": [ "(medicine, biology) An autoimmune disease that causes inflammation in the body and mostly affects men." ], "tags": [ "uncountable" ], "topics": [ "biology", "medicine", "natural-sciences", "sciences" ] } ], "word": "VEXAS" }
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This page is a part of the kaikki.org machine-readable All languages combined dictionary. This dictionary is based on structured data extracted on 2025-01-13 from the enwiktionary dump dated 2025-01-01 using wiktextract (4ba5975 and 4ed51a5). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.
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