plastosemiquinone

Also, DFT calculations on the plastosemiquinone anion radical in PSII found the histidine N δ to be the stronger of the two H-bond donors. 47 Therefore, the previous assignments of the hydrogen bond proton couplings for SQ A in PSII are not unambiguous. 46 From a comparative analysis of available nqi data for several semiquinone species and for copper complexes, 17 we find that the protonated imidazole nitrogens of these systems share similar valence orbital occupancies.

2014 July 15, Patrick J. O’Malley, Colin A. Wraight, Sergei A. Dikanov, “Hyperfine and Nuclear Quadrupole Tensors of Nitrogen Donors in the QA Site of Bacterial Reaction Centers: Correlation of the Histidine Nδ Tensors with Hydrogen Bond Strength”, in The Journal of Physical Chemistry. B, volume 118, →DOI:

(biochemistry) Any semiquinone derived from a plastoquinone


electromorph

(biochemistry) A mutant form of a protein identified by electrophoresis


attacin

en-noun

attacin (countable and uncountable, plural attacins)

Whereas sexual dimorphism was observed in relation to attacin only between males and females of the Pr group (LSD Post hoc, P ; Table 2 ), significant gender differences were found for defensin in both the UnPr and Pr groups (LSD Post-Hoc, P = 0.03 and P ).

2015 July 17, “Bacterial Exposure at the Larval Stage Induced Sexual Immune Dimorphism and Priming in Adult Aedes aegypti Mosquitoes”, in PLOS ONE, →DOI:

(biochemistry) An antibacterial protein originally found in the immune haemolymph of Hyalophora cecropia


bioreduction

bioreduction (countable and uncountable, plural bioreductions)

(biochemistry) biological / biochemical reduction


(biochemistry) An enzyme involved in the first major step of carbon fixation.


keratocan

(biochemistry) A protein that is important to the transparency of the cornea.


coxib

(biochemistry) Any COX-2 selective inhibitor.


ketoside

(biochemistry) Any glycoside of a ketose


polyglycine

Glycine loops are characterized by polyglycine repeats punctuated intermittently (every 3–6 residues in the head domain) by aromatic residues [46 ].

2015 July 17, “Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly”, in PLOS ONE, →DOI:

(biochemistry) Multiple glycine residues linked together as part of a polypeptide


Janus kinase

Shortened from just another kinase (being part of a large number of discoveries at the time); see Janus.

(biochemistry) Any of a family of intracellular non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.


tricellulin

(biochemistry) A transmembrane protein found in tight junctions.


prodelphinidin

prodelphinidin (countable and uncountable, plural prodelphinidins)

A study with pure prodelphinidin B3 and C2 showed that they inhibit the growth of prostate cancer cells through cell cycle arrest and caspase-3 activation.

2015 July 31, “Procyanidins Negatively Affect the Activity of the Phosphatases of Regenerating Liver”, in PLOS ONE, →DOI:

(biochemistry) The polymeric tannins, composed of gallocatechin, that yield delphinidin during depolymerization under oxidative conditions.


hemopressin

(biochemistry) An alpha hemoglobin fragment that binds cannabinoid receptors.


apoptogen

CHOP contributes to ER stress-induced macrophage death by inducing Fas activation, depletion of ER-associated calcium stores, and release of apoptogens from mitochondria.

2015 July 30, En Li et al., “FGF21 protects against ox-LDL induced apoptosis through suppressing CHOP expression in THP1 macrophage derived foam cells”, in BMC Cardiovascular Disorders, volume 15, →DOI:

(biochemistry) Any chemical substance that induces apoptosis.

apoptógeno

any chemical substance that induces apoptosis


asialofetuin

This optimized P145-ST reaction was applied successfully for α(2,6)-sialylation of asialofetuin, and this resulted in a large increase in the populations of multi-sialylated N-glycans compared with the reaction without addition of AP and CMP-Neu5Ac.

2015 August 1, “Enhanced Bacterial α(2,6)-Sialyltransferase Reaction through an Inhibition of Its Inherent Sialidase Activity by Dephosphorylation of Cytidine-5'-Monophosphate”, in PLOS ONE, →DOI:

(biochemistry) A glycoprotein that can be obtained from fetal calf serum.


chitotriose

chitotriose (countable and uncountable, plural chitotrioses)

(biochemistry) A chitosugar glycosaminotriose 2-amino-2-deoxy-β-D-glucopyranosyl-(1->4)-2-amino-2-deoxy-β-D-glucopyranosyl-(1->4)-2-amino-2-deoxy-D-glucose


glycosaminotriose

(biochemistry) Any triose containing glycosamine residues.


chitotriosidase

All three patients showed maintenance of platelets, hemoglobin and plasma chitotriosidase during a period of 4 to 8 years of subsequent miglustat therapy.

2015 June 23, Christine Serratrice, Laure Swiader, Jacques Serratrice, “Switching from imiglucerase to miglustat for the treatment of French patients with Gaucher disease type 1: a case series”, in Journal of Medical Case Reports, volume 9, →DOI:

(biochemistry) A chitinase whose activity is elevated in serum of patients suffering from lipid storage disorders


clastokine

In contrast, Semaphorin4D (Sema4D), another clastokine produced by OCs, inhibits OB differentiation.

2015 July 21, “The Crosstalk between Osteoclasts and Osteoblasts Is Dependent upon the Composition and Structure of Biphasic Calcium Phosphates”, in PLOS ONE, →DOI:

(biochemistry) Any of a class of cytokines derived from osteoclasts.


asialotriantennary

None of these enzymes could hydrolyze asialotriantennary nor asialotetraantennary oligosaccharides.

2015 July 22, “Transglycosylation Activity of Glycosynthase Mutants of Endo-β- N -Acetylglucosaminidase from Coprinopsis cinerea”, in PLOS ONE, →DOI:

(biochemistry) Describing a triantennary oligosaccharide that has no sialic acid component


asialobiantennary

Both Endo-CC1 and Endo-CC2 exhibited the hydrolase activity for high-mannose type and biantennary complex type oligosaccharides like Endo-M. Although Endo-M hydrolyzed asialobiantennary oligosaccharide containing bisecting GlcNAc, neither Endo-CC1 nor Endo-CC2 did.

(biochemistry) Describing a biantennary oligosaccharide that has no sialic acid component


asialotetraantennary

(biochemistry) Describing a tetraantennary oligosaccharide that has no sialic acid component


pectinolytic

(biochemistry) That hydrolyses pectin and related compounds


periaxin

For double immunostaining, p-NF was combined with periaxin.

2015 July 22, “Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation”, in PLOS ONE, →DOI:

(biochemistry) A structural protein that is required for the maintenance of myelin


preduodenal

A specific dose-response enrichment of the stomach tissue C8:0 was observed as a function of dietary C8:0, supporting the hypothesis of an early preduodenal hydrolysis of medium chain triglycerides and a direct absorption at the gastric level.

2015 July 22, “Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat”, in PLOS ONE, →DOI:

(biochemistry) Prior to a duodenal process


phosphoenzyme

Indeed, every reaction step measured in the Na,K-ATPase reaction cycle was significantly affected by the concentration of cholesterol: the phosphoenzyme levels increased, the apparent ATP affinity increased, the cytoplasmic Na + activation was inhibited at high Na + concentrations, and the rate of phosphorylation and of spontaneous and K + -activated dephosphorylation increased[51 –53 ].

2015 July 22, “Effects of Iron Overload on the Activity of Na,K-ATPase and Lipid Profile of the Human Erythrocyte Membrane”, in PLOS ONE, →DOI:

(biochemistry) The phosphorylated form of an enzyme


zymolyase

zymolyase (usually uncountable, plural zymolyases)

We show here that Mkk2 mediates the phosphorylation of the Mkc1 MAPK in response to cell wall assembly interfering agents such as zymolyase or tunicamycin and also to oxidative stress.

2015 July 22, “The Mkk2 MAPKK Regulates Cell Wall Biogenesis in Cooperation with the Cek1-Pathway in Candida albicans”, in PLOS ONE, →DOI:

(biochemistry) A commercial enzyme preparation that lyses the cell walls of yeast cells.


multisugar

(biochemistry) Relating to more than one sugar.


spinophilin

We have previously shown that spinophilin attenuates the α 2A AR-dependent hypotensive response; in spinophilin null mice, this response is highly potentiated.

2015 August 6, “Spinophilin Is Indispensable for the α 2B Adrenergic Receptor-Elicited Hypertensive Response”, in PLOS ONE, →DOI:

(biochemistry) A regulatory subunit of protein phosphatase-1 catalytic subunit, highly enriched in dendritic spines.


keratanase

(C) Immunoblotting of whole brain homogenates with the indicated antibodies following sequential digestion of the lysate with chondroitinase ABC, endo-β-galactosidase and keratanase I, SDS-PAGE on 5–15% gradient gels under non-reducing conditions, and transfer onto nitrocellulose membranes.

2009 February 11, Daniela Virgintino et al., “Differential distribution of aggrecan isoforms in perineuronal nets of the human cerebral cortex”, in Journal of Cellular and Molecular Medicine, volume 13, →DOI:

(biochemistry) Any enzyme that catalyses the hydrolysis of a keratan sulfate


xylotriose

xylotriose (countable and uncountable, plural xylotrioses)

(biochemistry) A trisaccharide consisting of three xylose residues.


xylopentaose

xylopentaose (countable and uncountable, plural xylopentaoses)

(biochemistry) A pentasaccharide consisting of five xylose residues.


xylotetraose

xylotetraose (countable and uncountable, plural xylotetraoses)

(biochemistry) A tetrasaccharide consisting of four xylose residues.


xyloheptaose

(biochemistry) A heptasaccharide consisting of seven xylose residues.


xylohexaose

xylohexaose (countable and uncountable, plural xylohexaoses)

(biochemistry) A hexasaccharide consisting of six xylose residues.


glycogenetic

On the other hand, there is an increase in insulin resistance due to a peripheral antagonist effect of HPL on glycolytic activity but not on lipogenic or glycogenetic activities.

2015, Asim Kurjak, Textbook of Perinatal Medicine, JP Medical, page 1036:

(biochemistry) Relating to glycogenesis.


fecosterol

The ERG6 gene (sterol methyltransferase) encodes an enzyme that participates in the ergosterol pathway, converting zymosterol to fecosterol.

2015 July 14, Tatiana Takahasi Komoto et al., “Gene Expression Response of Trichophyton rubrum during Coculture on Keratinocytes Exposed to Antifungal Agents”, in Evidence-based Complementary and Alternative Medicine : eCAM, volume 2015, →DOI:

(biochemistry) A sterol made by certain fungi and lichens.


glycosynthase

To control Fc N-glycans, we performed a rearrangement of Fc N-glycans from a heterogeneous N-glycosylation pattern to homogeneous N-glycans using chemoenzymatic approaches with two types of endo-β-N-acetyl glucosaminidases (ENG’ases), one that works as a hydrolase to cleave all heterogeneous N-glycans, another that is used as a glycosynthase to generate homogeneous N-glycans.

2015 July 23, “Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyses the formation of a glycoside.


bactenecin

Secondly, AMPs having one disulfide bond which pack into a loop structure having a tail e.g., bactenecins and esculentins.

2015 April 2, Babatunji Emmanuel Oyinloye et al., “Reactive Oxygen Species, Apoptosis, Antimicrobial Peptides and Human Inflammatory Diseases”, in Pharmaceuticals, volume 8, →DOI:

(biochemistry) Any of a family of antimicrobial cyclic peptides found in the granules of bovine neutrophils


coprisin

They concluded that coprisin could be a model molecule for a large family of novel AMPs possessing apoptotic activities.

(biochemistry) A peptide, similar to defensin, found in bacteria-immunized dung beetles


cathelin

Blend of cathepsin L + inhibitor, as coined in 1989.

Altogether, cathelicidins comprise an N-terminal cathelin domain and a C-terminal cationic antimicrobial domain, which is activated upon cleavage.

(biochemistry) The highly-conserved domain in all cathelicidin peptides


enkelytin

They commonly comprise peptides resulting from the processing of neuropeptide precursors like pro-enkephalin-A, to give active peptide B and enkelytin; many of which are phosphorylated.

(biochemistry) An antibacterial peptide produced by adrenal medullary chromaffin granules


postbiotic

(biochemistry) Any metabolite of a probiotic compound


ecometabolomics

Similar to proteomics, the majority of ecometabolomics studies have focused on demonstrating that distinct metabolic profiles are observed for organisms exposed to different types of chemical stressors either in the laboratory or in the field [ 40 ].

2015 May 29, Hyo Jeong Kim et al., “Ecotoxicogenomic Approaches for Understanding Molecular Mechanisms of Environmental Chemical Toxicity Using Aquatic Invertebrate, Daphnia Model Organism”, in International Journal of Molecular Sciences, volume 16, →DOI:

(biochemistry) The branch of metabolomics that studies the ecological effects on the metabolites of an organism.


prehepatic

Administration of intravenous edoxaban with and without rifampin may have differentiated the prehepatic versus hepatic effects of rifampin on parent and metabolite exposure.

2015 June 12, Jeanne Mendell et al., “The Effect of Rifampin on the Pharmacokinetics of Edoxaban in Healthy Adults”, in Clinical Drug Investigation, volume 35, →DOI:

(anatomy, biochemistry) upstream of the liver in the circulation of the hepatic portal system; and thus, before the metabolic effect of the liver.


rhamnosyltransferase

In addition, another gene having the function of flavonol 3- O -galactoside (1 → 4) rhamnosyltransferase remains to be cloned.

2015 May 23, Shaokang Di et al., “Linkage mapping, molecular cloning and functional analysis of soybean gene Fg3 encoding flavonol 3-O-glucoside/galactoside (1 → 2) glucosyltransferase”, in BMC Plant Biology, volume 15, →DOI:

(biochemistry) Any transferase that transfers a rhamnosyl group


preprotein

The strategies have been focused on production of stronger statins, MTP inhibitors such as Lomitapide, ACAT2 inhibitors, cholesteryl ester transfer protein (CETP) inhibitors such as Torcetrapib, Anacetrapib, Evacetrapib, and Dalcetrapib, antioxidants, squalene synthase inhibitors, preprotein convertase subtilisin kexin-9 inhibitors (PCSK9) such as Regeneron®, selective thyroid hormone mimetics such as Sobetirome as a β-receptor agonist, combination form of PPAR-α and γ agonists (Aleglitazar), PPAR-δ agonists (GW501516), and Apo A-I agonists (CSL-112) [ 116, 118 ].

2015 July 8, Ozra Tabatabaei-Malazy, Bagher Larijani, Mohammad Abdollahi, “Targeting metabolic disorders by natural products”, in Journal of Diabetes and Metabolic Disorders, volume 14, →DOI:

(biochemistry) A polypeptide chain that is in the process of growing into a protein by the addition of successive amino acid moieties


scleraxis

Then, MMP, PGE2, collagen and scleraxis expression was evaluated by RT-PCR (a and c) or ELISA (b).

2015 July 9, Catherine Baugé et al., “TOL19-001 reduces inflammation and MMP expression in monolayer cultures of tendon cells”, in BMC Complementary and Alternative Medicine, volume 15, →DOI:

transcription factor
transcription factor

(biochemistry) A transcription factor associated with tendon tissue


adenain

The LC-MS/MS analysis of proteinase K treated CsCl 2 density gradient purified TAdV-3 virions identified eleven virus-encoded proteins (hexon, pVI, pVII, penton base, pVIII, sialidase, IIIA, adenain, pX, IVa2 and DBP) previously reported to be in other adenoviruses (Table 3 and Figure 3 A).

2015 July 9, Pankaj Kumar et al., “Proteomic analysis of purified turkey adenovirus 3 virions”, in Veterinary Research, volume 46, →DOI:

(biochemistry) An endopeptidase that catalyses the cleavage of adenovirus proteins


chitohexose

The NAG in + NAG superimposes with the −2 position in the chitohexose in MltA.

2015 July 11, Doris H.X. Quay et al., “Structure of the stationary phase survival protein YuiC from B.subtilis”, in BMC Structural Biology, volume 15, →DOI:

(biochemistry) Any hexose derived from chitin


catabolome

The transcriptome data were confirmed by catabolome analysis, expression of periplasmic proteins and phenotypical analysis.

2015 July 24, “Effect of Global Regulators RpoS and Cyclic-AMP/CRP on the Catabolome and Transcriptome of Escherichia coli K12 during Carbon- and Energy-Limited Growth”, in PLOS ONE, →DOI:

(biochemistry, genetics) The complete set of catabolites found in a biological sample; especially that found in a person's body under normal conditions, and when suffering from a disease


cholinolytic

en-adj

cholinolytic (comparative more cholinolytic, superlative most cholinolytic)

more cholinolytic (comparative)
most cholinolytic (superlative)

(biochemistry) That counters the action of acetylcholine.


cholinolytic

(biochemistry) Any agent that counters the action of acetylcholine.


lanthipeptide

Notably, each of these two clusters, encoding a lanthipeptide and a bacteriocin, respectively, is shared with S.

2015 July 25, “A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea, an Uncommon Actinomycete”, in PLOS ONE, →DOI:

(biochemistry) Any peptide containing lanthionine


paucimannose

They found that N-linked glycans on DENV virions derived from mammalian cells were a mix of high-mannose sugars and complex sugars, while a mix of high-mannose sugars and paucimannose sugars were found on mosquito-derived virions.

2015 July 25, “Characterization of N-Glycan Structures on the Surface of Mature Dengue 2 Virus Derived from Insect Cells”, in PLOS ONE, →DOI:

(biochemistry) Having few mannose moieties


diabody

(biochemistry) A dimer of a fragment of an immunoglobin


triabody

(biochemistry) A trimer of a fragment of an immunoglobin


endoneuraminidase

en-noun

endoneuraminidase (usually uncountable, plural endoneuraminidases)

(biochemistry) An enzyme that catalyses the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.


chitosanase

(biochemistry) An enzyme that catalyses the endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan.


mycodextranase

mycodextranase (usually uncountable, plural mycodextranases)

(biochemistry) An enzyme that catalyses the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in alpha-D-glucans containing both (1->3)- and (1->4)-bonds.


fucoidanase

(biochemistry) An enzyme that catalyses the endohydrolysis of (1->2)-alpha-L-fucoside linkages in fucoidan without release of sulfate.


endogalactosaminidase

(biochemistry) An enzyme that catalyses the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).


feraxanase

feraxan endoxylanase
feraxan endoxylanase#English

(biochemistry) Synonym of feraxan endoxylanase


periphilin

(G) TASOR, MPP8, and periphilin form a complex.

2015 June 26, Iva A. Tchasovnikarova, “Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells"”, in Science, volume 348, →DOI, pages 1481–1485:

(biochemistry) Any of a family of proteins associated with the differentiation of skin cells


transautophosphorylation

PERK and IRE1 undergo dimerization and transautophosphorylation when activation and ATF6α is activated by regulated intramembrane proteolysis in the Golgi [26 ].

2015 July 28, “PDIA3 Knockdown Exacerbates Free Fatty Acid-Induced Hepatocyte Steatosis and Apoptosis”, in PLOS ONE, →DOI:

(biochemistry) autophosphorylation in which the active site is on a second kinase


degron

(biochemistry) A specific sequence of amino acids in a protein that directs the starting place of degradation.


endoglycosylceramidase

(biochemistry) An enzyme that catalyzes the chemical reaction oligoglycosylglucosylceramide + H₂O ⇌ ceramide + oligoglycosylglucose.


digestome

Shao et al. [ 54 ] have screened the caspase-1 digestome to identify caspase target proteins.

2008 September 13, Antero Salminen et al., “Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology”, in Journal of Cellular and Molecular Medicine, volume 12, →DOI:

(genetics, biochemistry) All the genes (and derived proteins) that relate to digestion (especially of complex carbohydrates)


invertasome

A single rotation will be favored in the Fis/enhancer-associated invertasome complex in part because the DNA segment between hixL-1 and the enhancer is only 155 bp.

2015 June 8, Yong Chang, Reid C. Johnson, “Controlling tetramer formation, subunit rotation and DNA ligation during Hin-catalyzed DNA inversion”, in Nucleic Acids Research, volume 43, →DOI:

(biochemistry) A nucleoprotein complex that causes inversion of a DNA sequence


endozymatic

(biochemistry) Relating to an endoenzyme


gliomedin

Recently, auto-antibodies against neurofascin-186 and gliomedin were described in more than 60% of patients with multifocal motor neuropathy.

2015 July 29, “Contactin-1 and Neurofascin-155/-186 Are Not Targets of Auto-Antibodies in Multifocal Motor Neuropathy”, in PLOS ONE, →DOI:

(biochemistry) An particular olfactomedin


autocyclization

autocyclization (usually uncountable, plural autocyclizations)

The chromophore responsible for the optical properties in GFP-like proteins is composed of X-Tyr-Gly and is able to form an imidazolinone structure through an autocyclization step, which involves the residues in the vicinity of the chromophore environment such as the highly conserved E215 and R95 in DsRed and the E222 and R96 in avGFP.

2015 July 29, “Chromophore Deprotonation State Alters the Optical Properties of Blue Chromoprotein”, in PLOS ONE, →DOI:

(biochemistry) The formation of a ring between two fragments of RNA.


perlustrin

The EGF domain has already been found in several reported SMPs from other Mollusca, such as perlustrin from H.

2015 July 29, “Layer-by-Layer Proteomic Analysis of Mytilus galloprovincialis Shell”, in PLOS ONE, →DOI:

(biochemistry) A protein found in the shell of abalones


methylenetetrahydrofolate reductase

(biochemistry) The rate-limiting enzyme in the methyl cycle, which catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate.


anhydromuropeptide

(biochemistry) A muropeptide containing a (normally terminal) anhydrosugar


biopeptide

(biochemistry) Any peptide of biological origin.


ectopeptidase

Considering the interaction of DPPIV/CD26 with extracellular matrix components and through regulation of E-cadherin, matrix metalloproteinases (MMPs), and tissue inhibitors of matrix metalloproteinases (TIMPs), it remains to be more clearly established whether tumor progression is more affected by the ectopeptidase activity or non-proteolytic mechanisms.

2015 July 30, “Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells”, in PLOS ONE, →DOI:


exocarboxypeptidase

All of these results clearly indicated that both DPP-IV and peptidase (s) (at least exocarboxypeptidase M) contributed to the ex vivo instability of two active GLP-1 peptides, similar to the observation of the peptides in their in vivo metabolism [38 ].

2015 July 30, “Degradation and Stabilization of Peptide Hormones in Human Blood Specimens”, in PLOS ONE, →DOI:

(biochemistry) An exoenzyme carboxypeptidase


cyanophycinase

cyanophycinase (countable and uncountable, plural cyanophycinases)

However, our findings showed no differential expression of the cyanophycinase genes (cphA, cphB) responsible for this process in response to irradiation, confirming that the cells did not seem to experience N-limitation.

2015 August 27, “Temporal Gene Expression of the Cyanobacterium Arthrospira in Response to Gamma Rays”, in PLOS ONE, →DOI:

(biochemistry) An enzyme that catalyzes the reaction [L-Asp(4-L-Arg)]ₙ + H₂O ⇌ [L-Asp(4-L-Arg)]ₙ₋₁ + L-Asp(4-L-Arg).


nephrocystin

(biochemistry) Any of a group of proteins, mutations in whose genes are associated with nephronophthisis.


prosaposin

(biochemistry) A glycoprotein that is a precursor for saposins A, B, C, and D.


baicalinase

One baicalinase and three baicalein 7-O-glucuronosyltransferases genes potentially involved in the transformation between baicalin/wogonoside and baicalein/wogonin were identified.

2015 August 29, “Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression”, in PLOS ONE, →DOI:

(biochemistry) An enzyme that catalyses the chemical reaction baicalin + H₂O ⇌ baicalein + D-glucuronate.


myoferlin

(biochemistry) A protein that is linked with skeletal muscle repair.


citrullinate

en-verb

citrullinate (third-person singular simple present citrullinates, present participle citrullinating, simple past and past participle citrullinated)

citrullinates (present singular third-person)
citrullinating (participle present)
citrullinated (participle past)
citrullinated (past)

From citrulline + -ate (verb-forming suffix).

It has been shown that PPAD is able to citrullinate bacterial as well as host peptides such as fibrinogen and α-enolase.

2015 August 29, Stefan Reichert et al., “Association of levels of antibodies against citrullinated cyclic peptides and citrullinated α-enolase in chronic and aggressive periodontitis as a risk factor of Rheumatoid arthritis: a case control study”, in Journal of Translational Medicine, volume 13, →DOI:

PADs do not typically citrullinate total arginines found in the amino acid sequence of a protein, but certain arginines are more susceptible to citrullination.[…]Likewise, PAD2 also citrullinates actin and myelin basic protein in the CNS, while PAD4 can citrullinate substrates like nucleophosmin, nuclear lamin C, and p21 (Lamensa and Moscarello 1993; Hagiwara et al. 2002; Tanikawa et al. 2012; Li et al. 2008).

2017, E. E. Witalison, L. J. Hofseth, “22: Citrullination in Inflammatory-Driven Carcinogenesis of the Colon”, in Anthony P. Nicholas, Sanjoy K. Bhattacharya, Paul R. Thompson, editors, Protein Deimination in Human Health and Disease, 2nd edition, Springer, page 433:

Furthermore, PPAD in contrast to human PAD is capable of citrullinating C-terminal arginine residues, which are generated by another Pg.-derived enzyme, arginine specific gingipain (Rgp) protease (81).

2020, Burkhard Möller, Florian Kollert, Anton Sculean, Peter M. Villiger, “79: Infectious Trigger in Periodontitis and the Gut in Rheumatoid Arthritis (RA)”, in Erminia Mariani, Mariagrazia Uguccioni, Daniela Frasca, editors, Immunobiology of Osteoarticular Diseases, Frontiers Media, page 83:

(biochemistry, transitive) To react with, or convert to, citrulline.


homocysteinase

Of our 30 genes, glutamate synthase and adenosyl homocysteinase were used for multiple gene analysis by Koufopanou et al.

2015 August 5, “Selection of Orthologous Genes for Construction of a Highly Resolved Phylogenetic Tree and Clarification of the Phylogeny of Trichosporonales Species”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyzes the breakdown of homocysteine


cytidyltransferase

In the CDP-choline pathway, externally added or endogenous choline is stepwise incorporated through phosphorylation by choline kinase and activation with CTP by phosphocholine cytidyltransferase.

2015 August 5, “Phosphatidylcholine Supply to Peroxisomes of the Yeast Saccharomyces cerevisiae”, in PLOS ONE, →DOI:

(biochemistry) Any transferase that transfers a cytidyl group


lipovitellin

en-noun

lipovitellin (countable and uncountable, plural lipovitellins)

(biochemistry) A protein found in egg yolk and involved in lipid and metal storage.


oxacillinase

(biochemistry) Any of the OXA group of beta-lactamases, found mainly in Acinetobacter species.


amastin

amastin (countable and uncountable, plural amastins)

(biochemistry) A transmembrane glycoprotein found in trypanosomatid parasites


apelin

(biochemistry) A peptide that is the endogenous ligand for the G-protein-coupled APJ receptor


apterin

(organic chemistry, biochemistry) A furanocoumarin, the glucoside of vaginol, found in Zizia aptera and other plants.


dysmetabolism

(biochemistry, pathology) metabolic dysfunction


urocortin

urocortin (countable and uncountable, plural urocortins)

(biochemistry) A potent anorexigenic peptide of 40 amino acids.


endolysin

Some phages lyse their hosts using a holin-endolysin system; however, in others, there is no interaction between the holin and the endolysin genes in host lysis [ 47 ].

2015 July 28, Tasha M. Santiago-Rodriguez et al., “Transcriptome analysis of bacteriophage communities in periodontal health and disease”, in BMC Genomics, volume 16, →DOI:


syntaphilin

Recently syntaphilin (SNPH) was identified, a protein that produces the docking/retaining of mitochondria in axons [ 74, 75 ].

2015 June 29, Fabian A. Cabezas-Opazo et al., “Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease”, in Oxidative Medicine and Cellular Longevity, volume 2015, →DOI:

(biochemistry) An axonal mitochondrial protein that disrupts synapse activity


immunoinhibit

en-verb

immunoinhibit (third-person singular simple present immunoinhibits, present participle immunoinhibiting, simple past and past participle immunoinhibited)

immunoinhibits (present singular third-person)
immunoinhibiting (participle present)
immunoinhibited (participle past)
immunoinhibited (past)

The titrations are based on the assumption that the volume of antiserum required to completely immunoinhibit enzyme activity is proportional to the amount of the enzyme in the tissue extract or biological fluid.

(biochemistry, immunology, transitive) to inhibit the immune response


autohydrolysis

FlhB undergoes asparagine-mediated autohydrolysis at N269-P270 [12 ,13 ].

2015 August 6, “Weak Interactions between Salmonella enterica FlhB and Other Flagellar Export Apparatus Proteins Govern Type III Secretion Dynamics”, in PLOS ONE, →DOI:

(biochemistry) hydrolysis of a peptide or enzyme catalyzed by itself


angioprotectin

Ang 1–7 and angioprotectin can bind to the Mas receptor (MasR) stimulating vasodilatation, inhibiting oxidative stress, fibrosis and cell proliferation.

2015 August 6, “Functional Local Renin-Angiotensin System in Human and Rat Periodontal Tissue”, in PLOS ONE, →DOI:

(biochemistry) A peptide, similar to angiotensin, that causes vasodilation


immunoexpress

immunoexpress (third-person singular simple present immunoexpresses, present participle immunoexpressing, simple past and past participle immunoexpressed)

immunoexpresses (present singular third-person)
immunoexpressing (participle present)
immunoexpressed (participle past)
immunoexpressed (past)

The lamina propria contains a range of inflammatory cells that normally immunoexpress the various immunoglobulins in plasma cells.

(biochemistry, immunology, transitive, intransitive) (of a protein) to express as a result of an immune response


hyalomin

(biochemistry) Any of a family of immunoregulatory peptides obtained from the salivary glands of hard ticks of the genus Hyalomma


legumain

(biochemistry) An enzyme that catalyses the hydrolysis of proteins and small-molecule substrates at -Asn-Xaa- bonds.


paragranulin

Five residues were included in the case of paragranulin, because this gave the best sequence alignment when paragranulins were compared with other N-half modules.

2015 August 7, “The Evolution of the Secreted Regulatory Protein Progranulin”, in PLOS ONE, →DOI:

(biochemistry) A particular peptide sequence within granulins


folylpolyglutamate

The best-ranked pair of reference genes from the developmental dataset included genes that encoded a phosphoglucomutase and a folylpolyglutamate synthase; genes that encoded a cullin and the same phosphoglucomutase as above were the most stable genes in the leaf gradient dataset.

2015 August 7, “Validating Internal Control Genes for the Accurate Normalization of qPCR Expression Analysis of the Novel Model Plant Setaria viridis”, in PLOS ONE, →DOI:

(biochemistry) A folyl derivative of polyglutamate that has a biochemical role in the central nervous system


atheronal

(biochemistry) Any of a group of ozone compounds found in human atherosclerotic arteries.


scaffoldin

(biochemistry) A large glycoprotein, one of the subunits of a cellulosome.


casamino acid

(biochemistry) Any of a mixture of amino acids and peptides obtained from acid hydrolysis of casein, typically used in microbial growth media.


intelectin

en-noun

intelectin (countable and uncountable, plural intelectins)

Most of up-regulated genes were related to innate immune responses, including innate immunity cells (macrophages, NK cell, mast cell, basophils) and innate immunity molecules (cytokines, chemokines, complement, lysozyme, intelectin 2).

2015 August 8, “An Immediate Innate Immune Response Occurred In the Early Stage of E . granulosus Eggs Infection in Sheep: Evidence from Microarray Analysis”, in PLOS ONE, →DOI:

(biochemistry) Any of a group of intestinal lactoferrin receptors.


depeptidize

en-verb

depeptidize (third-person singular simple present depeptidizes, present participle depeptidizing, simple past and past participle depeptidized)

depeptidizes (present singular third-person)
depeptidizing (participle present)
depeptidized (participle past)
depeptidized (past)

By introducing peptide isosteres, modifying the side chains of amino acids, and methylating amide nitrogens to depeptidize the molecule, the methylated Analog 7 was identified […]

2013 September 15, Anita Y. M. Howe, Srikanth Venkatraman, “The Discovery and Development of Boceprevir: A Novel, First-generation Inhibitor of the Hepatitis C Virus NS3/4A Serine Protease”, in Journal of Clinical and Translational Hepatology, volume 1, →DOI:

(transitive, biochemistry, organic chemistry) To remove the peptide bonds from.


humidimycin

(biochemistry) A peptide found in Streptomyces humidus.


pseurotin A

(biochemistry) A bioactive metabolite of Aspergillus.


perlucin

en-noun

perlucin (countable and uncountable, plural perlucins)

A 48kDa protein was extracted from the pearl of H.cumingii, providing evidence of vaterite formation and the matrix protein perlucin is reported to be involved in H.cumingii nacre formation.

2015 August 12, “A Novel Matrix Protein Hic31 from the Prismatic Layer of Hyriopsis Cumingii Displays a Collagen-Like Structure”, in PLOS ONE, →DOI:

(biochemistry) A matrix protein, found in nacre, that nucleates growth of calcium carbonate crystals


autorepression

An incomplete PadR motif is located in the p/o of lmrR, this palindromic sequence is only weakly recognized by LmrR. A proposed mechanism for the binding of LmrR to the p/o regions and the regulation of lmrCD and lmrR is as followed: the binding of two LmrR dimers to PlmrCD, together with an extensive binding of PlmrR by multiple LmrR dimers, results in a repression of lmrCD and a strong autorepression of lmrR.

2015 August 13, “Binding of the Lactococcal Drug Dependent Transcriptional Regulator LmrR to Its Ligands and Responsive Promoter Regions”, in PLOS ONE, →DOI:

(genetics, biochemistry) repression of the expression of a protein by the protein itself


tetracopeptide

Hop is comprised of three tetracopeptide domains: TPR1, TPR2A, TPR2B and two dipeptide repeats (DP): DP1 and DP2.

2015 August 13, “Plasmodium falciparum Hop (PfHop) Interacts with the Hsp70 Chaperone in a Nucleotide-Dependent Fashion and Exhibits Ligand Selectivity”, in PLOS ONE, →DOI:

(biochemistry) Any polypeptide containing twenty-four peptide units


autoregulator

LmrR was shown to be a transcriptional repressor of lmrCD expression and an autoregulator of its own expression.

(genetics, biochemistry) Any protein that regulates its own expression


extracatalytic

We conclude that Fu binds to Su(fu) and to Cos2 through distinct regions in the extracatalytic domain, (aa361-390 and aa504-805, respectively), and that disruption of Fu kinase activity does not affect the ability of Fu to bind to Su(fu) and Cos2.

2015 August 14, “A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response”, in PLOS ONE, →DOI:

(biochemistry) Outside the catalytic domain of an enzyme


tetrabrachion

The cytoplasmic (CD), tetramerization (TM) and stalk domains of the WT NA were replaced by an Ig-k secretion sequence, a 6xHis-tag, and a tetrabrachion domain for protein tetramerization.

2015 August 18, “Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay”, in PLOS ONE, →DOI:

(biochemistry) A highly thermostable surface protein, of unusual structure, isolated from an archaebacterium.


deglycation

When interpreting our results, physiological and biological differences between ethnic groups should also be considered (e.g. differences in red blood cell turnover, biological factors influencing non-enzymatic glycation or enzymatic deglycation of HbA1c independent of mean blood glucose [36 ]).

2015 August 22, “Impact of Maternal Country of Birth on Type-1-Diabetes Therapy and Outcome in 27,643 Children and Adolescents from the DPV Registry”, in PLOS ONE, →DOI:

(biochemistry) The removal of a sugar moiety from a glycoprotein


serotransferrin

A total of 16 differentially expressed proteins (7 upregulated, such as heat shock proteins and 9 downregulated, such as alpha-fetoprotein and, serotransferrin) were identified when Yorkshire gilts were compared with Meishan gilts on day 90 of gestation.

2015 August 26, “Proteomic Analysis of Fetal Ovary Reveals That Ovarian Developmental Potential Is Greater in Meishan Pigs than in Yorkshire Pigs”, in PLOS ONE, →DOI:

(biochemistry) A transferrin found in blood plasma


cyclosophoran

(biochemistry) A disaccharide that is a form of glucopyranosyl-glucopyranose


glucanosyltransferase

(biochemistry) Any transferase that transfers glucanosyl groups


neurotactin

neurotactin (countable and uncountable, plural neurotactins)

(biochemistry) The murine form of the chemokine protein.


metzincin

(biochemistry) Any of a family of protease enzymes with a zinc ion in their active sites.


systemin

(biochemistry) A plant peptide hormone involved in the wound response in the Solanaceae family.


beta-glucosidase

(biochemistry) A glucosidase enzyme, located on the brush border of the small intestine, that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules.


vitaminergic

Its vitaminergic actions and uses are identical to those of the hydrochloride.

1995, Alfonso R. Gennaro, Remington: The Science and Practice of Pharmacy:

We hypothesize that AA is a vitaminergic transmitter that activates the release of both FSH and LH from the anterior pituitary gland.
A schematic diagram of the hypothesized mechanism of action of AA as a vitaminergic neurotransmitter.

2001 September, S. Karanth, W. H. Yu, A. Walczewska, C. A. Mastronardi, S. M. McCann, Ascorbic acid stimulates gonadotropin release by autocrine action by means of NO, in Proc Natl Acad Sci USA (98(20): 11783–11788)

Ascorbic acid (AA) is a potent antioxidant that is known to affect mood, and it is the first known vitaminergic neurotransmitter (Karanth et al., 2000; Balz, 2003).

2013, N. S. Minka, J. O. Ayo, “Physiological and behavioral responses of goats to 12-hour road transportation, lairage and grazing periods, and the modulatory role of ascorbic acid”, in Journal of Veterinary Behavior: Clinical Applications:

(rare, biochemistry, neuroscience) Produced or activated by a vitamin


proteohormone

RbST is a proteohormone that can be used to increase milk production, but its administration is illegal in the EU [16 ] and of consumer’s concern in the USA. To detect rbST abuse, it has been shown that rbST-dependent protein biomarkers in serum and milk of dairy cows can be monitored, but levels are typically low (10 ng mL -1 range) [17 –19 ].

2015 August 27, “Calling Biomarkers in Milk Using a Protein Microarray on Your Smartphone”, in PLOS ONE, →DOI:

(biochemistry) Any protein that acts as a hormone


polyaminoacid

(biochemistry) A polypeptide having a single amino acid subunit


polythreonine

Experiments in vitro revealed even more amyloid-forming proteins and peptides, including proteins with no link to in vivo amyloids, such as polyaminoacids (e.g., polylysine, polythreonine and polyglutamic acid) [3 ], and short oligopeptides [4 –6 ].

2015 August 28, “pH-Driven Polymorphism of Insulin Amyloid-Like Fibrils”, in PLOS ONE, →DOI:

(biochemistry) A polyaminoacid composed of threonine subunits


homoarginine

homoarginine (countable and uncountable, plural homoarginines)

Arginine and homoarginine were detected at λex = 337 nm, λem = 520 nm, and λem = 454 nm was used for (ADMA) and symmetric dimethylarginine (SDMA).

2015 August 28, “Elevated Levels of Asymmetric Dimethylarginine (ADMA) in the Pericardial Fluid of Cardiac Patients Correlate with Cardiac Hypertrophy”, in PLOS ONE, →DOI:

(biochemistry) The amino acid (2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid


glycoxidation

glycoxidation (countable and uncountable, plural glycoxidations)

(biochemistry) The oxidation of sugars, glycoproteins or glycolipids


migfilin

Structure of migfilin peptide (blue) bound to the CD face of IgFLNa21 (green) (PDB ID:2W0P) [18 ].

2015 September 1, “Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20–21”, in PLOS ONE, →DOI:

(biochemistry) A protein implicated in control of integrin-mediated cell adhesion


endoxylanase

(biochemistry) Any xylanase that operates within a cell


glycoaminidase

We therefore treated the samples with PNGase F, a glycoaminidase capable of cleaving asparagine and N-acetylglucosamine residues in order to focus on quantitative analysis of the deglycosylated C1 without significant interference from the IgG band.

2015 September 2, “Prion Protein Protects against Renal Ischemia/Reperfusion Injury”, in PLOS ONE, →DOI:

(biochemistry) A glycosidase that catalyses the hydrolysis of an N-linked glycoside


neurobeachin

Two SNPs, rs14920313 and rs14920355, were located in the doublecortin-like kinase 1 (DCLK1) gene, and rs313140585 was identified in the neurobeachin (NBEA) gene.

2015 September 3, “Promising Loci and Genes for Yolk and Ovary Weight in Chickens Revealed by a Genome-Wide Association Study”, in PLOS ONE, →DOI:

(biochemistry) A protein that binds kinases to membranes


pseudoalterin

With pEV as expression vector and SM20429 as the host, a cold-adapted protease, pseudoalterin, which cannot be maturely expressed in E.

2015 September 3, “Development of a Cold-Adapted Pseudoalteromonas Expression System for the Pseudoalteromonas Proteins Intractable for the Escherichia coli System”, in PLOS ONE, →DOI:

(biochemistry) A metalloprotease isolated from deep-sea bacteria of a Pseudoalteromonas species.


malonylation

(organic chemistry, biochemistry) The addition of a malonyl group, especially to a lysine residue of a protein


acetamidase

The first equivalent system in mycobacteria, the acetamide-inducible system based on the Mycobacterium smegmatis (Msmeg) endogenous acetamidase promoter [13 ], was developed as late as in 1997.

2015 September 9, “Benzoic Acid-Inducible Gene Expression in Mycobacteria”, in PLOS ONE, →DOI:

(biochemistry) Any amidase that acts on an acetamide unit


agnoprotein

From a- + Latin gnōscō (“know”) + protein, in reference to agnogene, the gene from which polyomavirus family of agnoprotein emerges.

Expression of the viral proteins VP1 and agnoprotein was measured in whole cell protein extracts by Western blot.

2015 September 12, “CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection”, in PLOS ONE, →DOI:

(biochemistry) Any of a family of viral proteins that play indirect roles in the biological processes and activities of viruses


vasohibin

Among these, we looked at vasohibin for further study, since its expression increased by about 3 times.

2015 September 12, “Inhibition of IGF-1-Mediated Cellular Migration and Invasion by Migracin A in Ovarian Clear Cell Carcinoma Cells”, in PLOS ONE, →DOI:

(biochemistry) Any of a family of angiogenesis inhibitors found in the endothelium


immunometabolism

In fact, a novel research area termed immunometabolism has emerged from the study of AT’s roles in metabolism and immunity, which contribute to the pathogenesis of obesity-associated dysfunctions [23, 24 ].

2015 September 15, “Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-α”, in PLOS ONE, →DOI:

(immunology, biochemistry) The study of the interaction between the immune system and metabolism


octaose

(biochemistry) Any oligosaccharide containing eight monosaccharide moieties


maltooctaose

We tested if redox sensitivity—defined as a percentage difference between reduced (set as 100%) and oxidized activity—is dependent on the nature of the glucan substrate using a linear series of maltooligosaccharides (MOS) from glucose to maltooctaose and glycogen as substrates.

2015 September 15, “The Role of Cysteine Residues in Redox Regulation and Protein Stability of Arabidopsis thaliana Starch Synthase 1”, in PLOS ONE, →DOI:

(biochemistry) An oligosaccharide composed of four maltose moieties


polyglucan

It has a structural fold termed GT-B and a retaining mechanism of glucose transfer giving an α-configuration of the growing polyglucan chain (http://www.cazy.org/ ).

(biochemistry) Any polysaccharide containing glucan units


prostasin

Aprotinin exhibited nearly stoichiometric inhibition of prostasin and matriptase, but was much weaker towards HAT and was completely ineffective versus tryptase.

2015 October 21, “Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases”, in PLOS ONE, →DOI:

(biochemistry) A particular protein that is implicated in epithelial sodium channel regulation.


matriptase

matriptase (usually uncountable, plural matriptases)

From matri- (because of its use in treating breast cancer) + tryp(sin) + -ase?

af

Stoichiometric release of 6-amidino-2-naphthol allowed highly sensitive fluorometric estimation of active-site concentration in preparations of matriptase and tryptase.

(biochemistry) An enzyme that cleaves various kinds of synthetic substrate.


TMH

(biochemistry) Abbreviation of trimethylhydrazine hydrochloride.


phosphometabolite

Our study uncovered age-dependent decline in phosphometabolite turnover rates and dynamic energetic rearrangements in aging rat atria with simultaneous phosphotransfer circuit and mitochondrial substrate shuttle deficits hindering ATP cycling that may underlie the vulnerability of the whole energetic system, muscle weakness and electrical instability.

2015 September 18, “Decline of Phosphotransfer and Substrate Supply Metabolic Circuits Hinders ATP Cycling in Aging Myocardium”, in PLOS ONE, →DOI:

(biochemistry) Any metabolite that contains a phosphate (or similar) group


heterododecamer

(chemistry, biochemistry) A dodecamer, especially a biologically active one, derived from two or more different (but similar) monomers


zonadhesin

This is the case of zonadhesin, a protein from the family of agglutinins that was used as an anchor by Zhang et al.

2015 October 29, “Displaying Lipase B from Candida antarctica in Pichia pastoris Using the Yeast Surface Display Approach: Prospection of a New Anchor and Characterization of the Whole Cell Biocatalyst”, in PLOS ONE, →DOI:

(biochemistry) A male reproductive protein associated with cell adhesion.


(biochemistry) Abbreviation of casein kinase 2.


anabolite

(biochemistry) Any substance produced as a result of anabolism


dermorphin

en-noun

dermorphin (countable and uncountable, plural dermorphins)

BSA showed a clear liver distribution, while dermorphin was mainly distributed in the duodenum, followed by the liver, 15 min after i.v. injection.

2015 November 5, “Quorum Sensing Peptides Selectively Penetrate the Blood-Brain Barrier”, in PLOS ONE, →DOI:

(biochemistry) A heptapeptide first isolated from the skin of South American frogs, and sometimes used illicitly to enhance the performance of racehorses.


BSG

BSG (countable and uncountable, plural BSGs)


polysaccharase

(biochemistry) Any enzyme that degrades/hydrolyses a polysaccharide.


hydroperoxyflavin

(biochemistry) Any of a family of metabolites formally generated by the addition of the elements of hydrogen peroxide to a flavin


glucometabolic

This work provides the context for continued mechanistic studies of the CX3CL1 pathway, in concert with other chemokines, on glucometabolic as well as cardiovascular traits, specific interrogation of human chemokine genetics in these traits and the potential for development of novel therapies targeting these pathways.

2015 September 23, “Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice”, in PLOS ONE, →DOI:

(biochemistry) Relating to the metabolism of sugars


sporamin

sporamin (countable and uncountable, plural sporamins)

Much less is known too in terms of the interactions of nematode feeding and the KPIs. In transgenic studies, over-expression of the sporamin gene from sweet potato in sugar beet did reduce the growth and development of the sugar beet cyst nematode, H.

2015 September 23, “Transcription of Biotic Stress Associated Genes in White Clover ( Trifolium repens L .) Differs in Response to Cyst and Root-Knot Nematode Infection”, in PLOS ONE, →DOI:

(biochemistry) A storage protein found in the tubers of sweet potato


gluzincin

(biochemistry) Any of a particular class of metalloprotease containing glutamic acid and zinc


cephalosporinase

Resistance to β-lactams is mainly due to enzymatic degradation by a chromosomal cephalosporinase, plasmid-mediated broad spectrum β-lactamases, and recently acquired carbapenemases [4, 6, 7, 9 –14 ].

2015 September 24, “In Vivo Evolution of Bacterial Resistance in Two Cases of Enterobacter aerogenes Infections during Treatment with Imipenem”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that hydrolyses (the lactam ring of a ) cephalosporin


magnesiotropic

Moreover, the mRNA levels of magnesiotropic and calciotropic genes were examined in the large intestine and kidney by real-time PCR. Results Treatment with omeprazole significantly reduced serum Mg 2+ and Ca 2+ levels.

2015 September 24, “Dietary Inulin Fibers Prevent Proton-Pump Inhibitor (PPI)-Induced Hypocalcemia in Mice”, in PLOS ONE, →DOI:

(biochemistry) Describing any material (especially a hormone) that is involved in the regulation of magnesium in the blood and in bone


angiokinase

We believe that this study could provide a basis for developing angiokinase inhibitors having high affinity for the epidermal growth factor receptor, from the pyrimidine scaffold.

2015 September 25, “Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that promotes angiogenesis


deglycosylase

To deglycosylate the WT hENT1 and ∆IL6, 100 μg of the proteins were incubated with 10 μl of the deglycosylase mix (NEB) at 37°C and analyzed by SDS-PAGE. Each experiment was performed in triplicate on different batches of oocytes.

2015 September 26, “The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyses the removal of glycosyl groups


fructosyltransferase

The fructosyltransferase activity was 1.9 U mg −1, where 1 unit is the amount of enzyme required to perform the transfer of 1 μmol of fructose per minute at a working temperature of 37°C and a sucrose concentration of 100 g L −1 at pH 6.0 (50 mM potassium phosphate buffer).

2015 September 26, “Valorization of Cheese and Tofu Whey through Enzymatic Synthesis of Lactosucrose”, in PLOS ONE, →DOI:

(biochemistry) Any transferase that catalyses the transfer of a fructosyl group


fructosidase

Levansucrase expressed a specific fructosidase activity of 2.9 units per milligram (U mg -1 ), where 1 unit is defined as the amount of enzyme releasing 1 μmol of glucose per minute at a working temperature of 37°C and a sucrose concentration of 100 g L −1 at pH 6.0 (50 mM potassium phosphate buffer).

(biochemistry) Any glycosidase that catalyses the hydrolysis of a fructoside


metalloaminopeptidase

Interestingly, some of them contain chemical scaffolds already associated with other metalloaminopeptidase inhibitors, providing a further validation of the computational results.

2015 September 26, “Identification and Validation of a Potent Dual Inhibitor of the P . falciparum M1 and M17 Aminopeptidases Using Virtual Screening”, in PLOS ONE, →DOI:

(biochemistry) Any metalloenzymatic aminopeptidase


melanoregulin

Two known binding partners of RDS fall into this category, calmodulin and melanoregulin, both of which are thought to regulate the fusogenic capability of RDS.

2015 September 26, “SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting”, in PLOS ONE, →DOI:

(biochemistry) A protein (and associated gene) that regulates the activity of melanosomes


xanthanolide

The data allowed us to hypothesize that miR6435 might play a role in the regulation of xanthanolide biosynthesis in X.

2015 September 26, “Differential microRNA Analysis of Glandular Trichomes and Young Leaves in Xanthium strumarium L. Reveals Their Putative Roles in Regulating Terpenoid Biosynthesis”, in PLOS ONE, →DOI:

(biochemistry) Any of several glycosides containing xanthan.


transfructosylation

Nonetheless, to the best of our knowledge, the capacity of raffinose and stachyose to act as fructosyl donors in transfructosylation reactions catalyzed by the levansucrase of B.

(biochemistry) The transfer of fructosyl groups within or between molecules


salacinol

(biochemistry) A polyphenol found in the root bark of Salacia plants.


multichaperone

The complex containing Cdc37 and p23 is thought to be the primary stable form, and the HSP70- and HOP-associated complex is another proteasome-targeting form that induces ubiquitin-proteasome degradation [45, 46 ]. 17-AAG is an ansamycin antibiotic that binds to HSP90 and inhibits the formation of the stabilized HSP90-client protein complex, resulting in the accumulation of the proteasome-targeting HSP90-based multichaperone.

2015 September 29, “The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein”, in PLOS ONE, →DOI:

(biochemistry) A chaperone consisting of multiple proteins


kotalanol

Salacinol and kotalanol concentrations in the SRE powder were 4.17 ± 0.13 and 2.26 ± 0.12 μg/mg, respectively.

2015 December 3, “Improvement in Human Immune Function with Changes in Intestinal Microbiota by Salacia reticulata Extract Ingestion: A Randomized Placebo-Controlled Trial”, in PLOS ONE, →DOI:


fungalysin

(biochemistry) Any of a class of metallopeptidases found in mushrooms of the genus Coprinopsis.


glycoallergen

(biochemistry, immunology) Any glycoside allergen.


ovastacin

ovastacin (countable and uncountable, plural ovastacins)

(biochemistry) An astacin found in oocytes, involved in the hardening of the zona pellucida


DNP

DNP (countable and uncountable, plural DNPs)

dendroaspis natriuretic peptide
dendroaspis natriuretic peptide#English

(biochemistry) Initialism of dendroaspis natriuretic peptide.


rhodocytin

The maximum concentration of rhodocytin, a potent CLEC-2 agonist, resulted in release of approximately 60% 5-HT or PDGF, whereas CASMCs stimulated 20% release from WT platelets.

2015 September 30, “Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis”, in PLOS ONE, →DOI:

(biochemistry) A protein found in venom of the viper Calloselasma rhodostoma


polysialyltransferase

Considering gene function, ST8SIA2 could be related to the putative pathological mechanism of both schizophrenia and BD. Animal studies have shown that the amount of polySia synthesized by polysialyltransferase encoded by ST8SIA2 is crucial during brain development [42, 43 ].

2015 September 30, “Association between ST8SIA2 and the Risk of Schizophrenia and Bipolar I Disorder across Diagnostic Boundaries”, in PLOS ONE, →DOI:

(biochemistry) Any transferase that promotes polysialylation


rapsyn

Short for receptor-associated protein of the synapse.

(biochemistry) A protein believed to play a role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites.


monophenolase

Then the inhibitory effects of the three compounds on monophenolase activity of tyrosinase were also determined.

2015 October 1, “Synthesis of Triazole Schiff’s Base Derivatives and Their Inhibitory Kinetics on Tyrosinase Activity”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyzes the oxidation of simple phenols


sulfokine

(biochemistry) A pentapeptide (tyrosine - isoleucine - tyrosine - threonine - glycine) with a sulfate group attached to each of the two tyrosine moieties


melibionic acid

(biochemistry) A disaccharide formed from glucose and gluconic acid


choriogenin

Among these six tissues, the intestine showed the highest space response with 10 genes categorized as oxidation–reduction processes (gene ontogeny term GO:0055114), and the expression levels of choriogenin precursor genes were suppressed in the ovary.

2015 October 2, “Histological and Transcriptomic Analysis of Adult Japanese Medaka Sampled Onboard the International Space Station”, in PLOS ONE, →DOI:

(biochemistry) Any of a group of proteins that are precursors to the formation of the chorion of an egg


forisome

This statement is supported by in-vitro experiments data where extracted forisomes responded to application of aphid salivary compounds.

2015 December 8, “Application of Brown Planthopper Salivary Gland Extract to Rice Plants Induces Systemic Host mRNA Patterns Associated with Nutrient Remobilization”, in PLOS ONE, →DOI:

(biochemistry) Any of a class of proteins occurring in the sieve tubes of Fabaceae.


meizothrombin

meizothrombin (usually uncountable, plural meizothrombins)

From Ancient Greek μείζων (meízōn, “greatet”) + thrombin.

affix

(biochemistry) A particular intermediate in thrombin metabolism.


paracoccin

(biochemistry) A lectin found in Paracoccidioides brasiliensis.


casease

(biochemistry) An exoenzyme that hydrolyzes casein.


antiterminator

Our results demonstrated up-regulation of tagatose pathway genes, Leloir pathway genes, lactose-specific IIA & IIBC component encoding genes (lacF2and lacE2), and the lacT gene, encoding a transcriptional antiterminator.

2015 October 3, “The Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofilm Growth In Vitro”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that promotes antitermination


phosphocarrier

Similarly, expressions of the ptsH gene, encoding the phosphocarrier protein HPr, and the SPD_0082 gene, encoding a sensor histidine kinase, were down-regulated 1.6- and 1.4-fold, respectively.

(biochemistry) A class of cytoplasmic protein that is involved in the phosphorylation of sugars


oligomannoside

(biochemistry) An oligomer containing mannoside moieties


mannoside

(biochemistry) Any glycoside of mannose.


trimannose

Exogenous glucocerebrosidase is administered intravenously into patients and glucocerebrosidase preparation currently involves either extraction directly from human placenta or recombinant expression in CHO cells (Cerezyme ® ), which requires in vitro post-purification exoglycosidase digestions to unravel the trimannose core (Man 3 GlcNAc 2 ) using a combination of sialidase, galactosidase, and N-acetylglucosaminidase.

2015 October 6, “Biochemical Characterization of Human Anti-Hepatitis B Monoclonal Antibody Produced in the Microalgae Phaeodactylum tricornutum”, in PLOS ONE, →DOI:


automethylation

The Metnase SET domain is not only responsible for dimethylation of H3K36 [3, 6 ] but also crucial for automethylation at K485 within the catalytic pocket [8 ].

2015 October 6, “The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage”, in PLOS ONE, →DOI:

(biochemistry) methylation of a protein catalysed by the protein itself


hepatokine

(biochemistry) Any of several cytokines found in the liver


bioscavenger

The exact physiological function of BChE remains elusive, although it acts as an endogenous bioscavenger for anticholinesterase agents.

2015 October 8, “New Insights into Butyrylcholinesterase Activity Assay: Serum Dilution Factor as a Crucial Parameter”, in PLOS ONE, →DOI:


peptase

en-noun

peptase (countable and uncountable, plural peptases)

(biochemistry) A form of pepsin obtained from malt.


peptidolysis

(biochemistry) The cleavage or digestion of peptides.


regucalcin

regucalcin (countable and uncountable, plural regucalcins)

It is hypothesized that regucalcin might have a role in regulation of calcium mediated signaling or in inhibiting calcium-mediated defenses in plant cells in response to herbivory.

2016 January 21, “Insight into the Salivary Gland Transcriptome of Lygus lineolaris (Palisot de Beauvois)”, in PLOS ONE, →DOI:

(biochemistry) A calcium-binding protein that is preferentially expressed in the liver and kidney and may be associated with aging.


metalloelastase

metalloelastase (countable and uncountable, plural metalloelastases)

(biochemistry) An enzyme that catalyzes the hydrolysis of soluble and insoluble elastin.


tyrosination

tyrosination (countable and uncountable, plural tyrosinations)

They include posttranslational modifications such as tyrosination, acetylation and glutamylation, as well as MT growth, pausing and shortening.

2015 October 15, “A Cilia Independent Role of Ift88/Polaris during Cell Migration”, in PLOS ONE, →DOI:

(biochemistry) modification by reaction with tyrosine


humanin

(biochemistry) A polypeptide that has neuroprotective and cytoprotective properties.


pectocellulose

pectocellulose (countable and uncountable, plural pectocelluloses)

(obsolete, biochemistry) A form of cellulose once thought to be a component of pectin.


nutriregulation

The nutrition model of food deprivation used in this study was a large challenge, so further studies should be performed with a diet that could be applied by livestock farmers in order to identify the nutriregulation of miRNA under breeding conditions.

2015 October 17, “Food Deprivation Affects the miRNome in the Lactating Goat Mammary Gland”, in PLOS ONE, →DOI:


cytidylyltransferase

The CDP-choline pathway can occur in all nucleated cells and is involved in producing PC from choline, ATP, CTP and diacylglycerol, catalyzed by the enzymes choline kinase, choline-phosphate cytidylyltransferase and diacylglycerol cholinephosphotransferase [44 ].

2015 October 22, “Influence of Development and Dietary Phospholipid Content and Composition on Intestinal Transcriptome of Atlantic Salmon ( Salmo salar )”, in PLOS ONE, →DOI:

(biochemistry) Any transferase that transfers a cytidylyl group


glycotransferase

CG33303 is predicted to have the dolichyl-diphosphooligosachharide-protein glycotransferase activity based on its similarity with human Ribophorin I. As candidates from this class show differential effect on different tendon cell clusters i.e. dorsal-anterior and posterior tendon cell cluster it would be interesting to investigate their role in specifying these tendon cell clusters.

2015 October 22, “A Tendon Cell Specific RNAi Screen Reveals Novel Candidates Essential for Muscle Tendon Interaction”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyzes the transfer of a sugar moiety


leupaxin

(biochemistry) A particular protein that is preferentially expressed in hematopoietic cells and is most homologous to the focal adhesion protein paxillin.


exorhodopsin

The different usage of Gt2 and Gt1 for parapinopsin and exorhodopsin in the teleost pineal organ is similar to that for cone opsins and rhodopsin in the retina, although the physiological implications are unclear.

2015 October 23, “Activation of Transducin by Bistable Pigment Parapinopsin in the Pineal Organ of Lower Vertebrates”, in PLOS ONE, →DOI:

(biochemistry) A form of rhodopsin expressed in the zebrafish pineal gland


parietopsin

It has been reported that parietopsin, first identified in the parietal eye, is colocalized with and coupled to Go-type G protein in the photoreceptor cells of the lizard parietal eye [31 ].

(biochemistry) Any of a group of opsins in the parietal eye of some lizards


parapinopsin

We previously reported that parapinopsin is an ultraviolet (UV)-sensitive opsin that underlies hyperpolarization of the pineal photoreceptor cells of lower vertebrates to achieve pineal wavelength discrimination.

(biochemistry) Any of a group of opsins in the parapineal gland of some fish


metamelanopsin

In squid and octopus rhodopsins, acid metarhodopsin (all-trans form) shows light-dependent conversion mainly to the original rhodopsins (11-cis form) at 0°C [16, 17 ], whereas metamelanopsin (all-trans form) is converted to extramelanopsin (7-cis form) in addition to the original melanopsin (11-cis form) [10 ].

2015 October 23, “Diversity of Active States in TMT Opsins”, in PLOS ONE, →DOI:

(biochemistry) A form of melanopsin containing the all-trans isomer of retinal


triphosphohydrolase

A key player of this restriction is the sterile alpha motif-hydroxylase domain 1 protein (SAMHD1, [6 ,7 ,14 ], a dGTP-dependent deoxynucleotide triphosphohydrolase that maintains dNTPs at concentrations that are limiting for efficient reverse transcription [5 ,16 ,17 ,18 ,19 ,20 ]).

2015 October 24, “The Frequency of Cytidine Editing of Viral DNA Is Differentially Influenced by Vpx and Nucleosides during HIV-1 or SIV MAC Infection of Dendritic Cells”, in PLOS ONE, →DOI:

(biochemistry) Any hydrolase that catalyses the hydrolysis of triphosphates


tetramannose

tetramannose (countable and uncountable, plural tetramannoses)

This range is similar to x β of 0.35 nm reported for GAG self-interactions [48 ] and linear tetramannose interacting with a monoclonal antibody [51 ] both being examples being interactions involving carbohydrates.

2015 October 24, “Energy Landscape of Alginate-Epimerase Interactions Assessed by Optical Tweezers and Atomic Force Microscopy”, in PLOS ONE, →DOI:


GAR

glycineamide ribonucleotide
glycineamide ribonucleotide#English

(biochemistry) Initialism of glycineamide ribonucleotide.

glutathione amide reductase
glutathione amide reductase#English

(biochemistry) Initialism of glutathione amide reductase.


endocellulase

(biochemistry) Any cellulase that hydrolyses glycoside links within (rather than at the ends of) cellulose chains.


stercolin

(biochemistry, archaic) serolin; stercorin


acetylator

(biochemistry) A human being or other organism that can metabolize certain drugs by acetylating them (to a greater or lesser extent).


ghrelinergic

Together, these results described for the first time in fish the mapping of preproghrelin and ghrelin receptor ghs-r1a in brain and gastrointestinal tract of goldfish, and provide the first evidence for a daily regulation of both genes expression in such locations, suggesting a possible connection between the ghrelinergic and circadian systems in teleosts.

2015 October 28, “In Situ Localization and Rhythmic Expression of Ghrelin and ghs-r1 Ghrelin Receptor in the Brain and Gastrointestinal Tract of Goldfish ( Carassius auratus )”, in PLOS ONE, →DOI:

(biochemistry) Relating to the activity or function of the ghrelin hormone


propionigenesis

Nitrate reduction can compete with propionigenesis for reducing equivalents as it is thermodynamically more favorable, diverting glucose fermentation away from the propionigenesis into acetate in Dairy1 and butyrate in Dairy 2.

2015 October 29, “Does Dietary Mitigation of Enteric Methane Production Affect Rumen Function and Animal Productivity in Dairy Cows?”, in PLOS ONE, →DOI:

(biochemistry) The biogenesis of propionate (especially from carbohydrates).


glycosaminidase

(biochemistry) Any enzyme that catalyses the hydrolysis of chitin or similar amino-polysaccharides


iminopeptide

(biochemistry) A dehydrogenated peptide in which the -CO-NH-CHR-CO₂- groups are replaced by -CO-N=CR-CO₂-


ketolase

(biochemistry) Any enzyme that cleaves carbohydratea at the ketone (carbonyl) position


phosphoesterase

(biochemistry) Any enzyme that catalyses the hydrolysis of a phosphate enzyme.


metallophosphoesterase

(biochemistry) Any phosphoesterase that is a metalloenzyme


polylactosamine

(biochemistry) A polysaccharide having lactosamine components


sialyloligosaccharide

(biochemistry) Any oligosaccharide related to sialic acid


uroplakin

(biochemistry) Any of a particular family of transmembrane proteins


presequence

(biochemistry) A sequence of amino acids in a preprotein; the sequence of amino acids at the N-terminal end of a protein


toll-like

(biochemistry) Of or relating to a class of proteins, involved in the immune system, that resemble the protein coded by a toll gene.


resatorvid

Moreover, a recent study revealed that intracerebroventricular injection of the pharmacological TLR4-NOX4 signal inhibitor resatorvid protects against neuronal death in transient focal ischemia.

2016 February 6, “Evaluation of the Therapeutic Potential of Anti-TLR4-Antibody MTS510 in Experimental Stroke and Significance of Different Routes of Application”, in PLOS ONE, →DOI:

(biochemistry) A particular TLR4 signal inhibitor.


luteotropin

luteotropin (countable and uncountable, plural luteotropins)

(biochemistry) Prolactin; a peptide gonadotrophic hormone secreted by the pituitary gland that stimulates growth of the mammary glands and lactation in females.


mammotropin

mammotropin (countable and uncountable, plural mammotropins)


lactotropin

lactotropin (countable and uncountable, plural lactotropins)


bioneogenesis

CHL inhibits the protein synthesis that impacts among other protein expression the bioneogenesis of enzymes such as esterases, whereas AMP targets the bacterial cell wall synthesis.

2015 October 30, “Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester”, in PLOS ONE, →DOI:

(biochemistry) The neogenesis of biochemically active compouds


leishporin

Based on our findings that Leishmania have a pore-forming cytolysin that we call leishporin, we have been proposing that amastigotes egress from the macrophages is mediated by pore formation on the parasitophorous vacuole and the plasma membrane.

2015 October 30, “Distinct Macrophage Fates after in vitro Infection with Different Species of Leishmania : Induction of Apoptosis by Leishmania (Leishmania) amazonensis, but Not by Leishmania (Viannia) guyanensis”, in PLOS ONE, →DOI:

(biochemistry) A porin isolated from species of Leishmania


polychitin

Chitinases expressed during plant-pathogen interactions are associated with plant defense against pathogens, which can catalyze polychitin molecules that are present in the cell walls of most fungi and homologues in plant-pathogen interactions [43 ].

2015 October 30, “Proteomic Analysis of the Relationship between Metabolism and Nonhost Resistance in Soybean Exposed to Bipolaris maydis”, in PLOS ONE, →DOI:


bitopic

However, allosteric biased ligands may confer functional selectivity by exploiting the recently solved extracellular vestibule [50 ] to generate noncompetitive negative or positive allosteric modulators [51 ] or bitopic ligands [52 ].

2015 October 31, “Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity”, in PLOS ONE, →DOI:

(biochemistry, of a protein) That links two separate domains


glycomolecule

(biochemistry) Any substance related to simple carbohydrates, but especially such a compound present in a biological macromolecule


biosilicification

biosilicification (countable and uncountable, plural biosilicifications)

(biochemistry) biological or biochemical silicification


biocalcify

en-verb

biocalcify (third-person singular simple present biocalcifies, present participle biocalcifying, simple past and past participle biocalcified)

biocalcifies (present singular third-person)
biocalcifying (participle present)
biocalcified (participle past)
biocalcified (past)

In order to understand what genetic repertoire may have been present in the last common ancestor of the Metazoa (LCAM), and that may have contributed to the evolution of the ability to biocalcify, we have studied the skeletal proteome of the coralline demosponge Vaceletia sp. and compare this to other metazoan biomineralizing proteomes.

2015 November 5, “The Skeleton Forming Proteome of an Early Branching Metazoan: A Molecular Survey of the Biomineralization Components Employed by the Coralline Sponge Vaceletia Sp.”, in PLOS ONE, →DOI:

(biochemistry) To calcify biologically or biochemically


malformin

The pure compound was identified as malformin C via comparison of data with those previously reported [16 ].

2015 November 6, “Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug”, in PLOS ONE, →DOI:

Aspergillus niger
Aspergillus niger#Translingual

(biochemistry) Any of a group of bicyclic peptides, produced by Aspergillus niger or close relatives, that are mycotoxins.


mitocalcin

With a focus on genes implicated in mitochondrial Ca 2+ transport and membrane potential, uncoupling protein 2 (Ucp2), mitocalcin (Efhd1), mitochondrial calcium uptake 1 (Micu1), mitochondrial calcium uniporter (Mcu), mitochondrial calcium uniporter regulator 1 (Mcur1), cytochrome c oxidase subunit 1 (COX1), and ATP synthase subunit β (Atp5b) were found to be up-upregulated.

2015 November 6, “Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells”, in PLOS ONE, →DOI:

(biochemistry) A mitochondrial calcium-binding protein


glycoconjugated

Rutin (quercetin-3-O-rutinoside) is one of the main glycoconjugated forms of quercetin present in planta, and its antioxidant properties and pharmacological benefits for the treatment of chronic diseases such as cancer, diabetes, hypertension and hypercholesterolemia have been recently reviewed [5 ].

2015 November 7, “Lactobacillus acidophilus —Rutin Interplay Investigated by Proteomics”, in PLOS ONE, →DOI:

(biochemistry) conjugated with a carbohydrate


macrolactin

In the present study, we report that 7-O-succinyl macrolactin A (SMA) suppresses tumor growth by stabilizing the β-catenin destruction complex, which was achieved through inhibition of regulatory components associated with the complex.

2015 November 7, “The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt”, in PLOS ONE, →DOI:

(biochemistry) An antibacterial peptide produced by the silkworm Bombyx mori; the gene responsible for its production


rhamnosidase

In particular, the rhamnosidase from Lactobacillus acidophilus was able to efficiently degrade flavanone and flavonol glycosides such as hesperidin, naringin and rutin [11 ].

(biochemistry) Any enzyme that catalyzes the hydrolysis of a rhamnoside.


succinylase

The succinylase branch utilizes succinyl-CoA to generate succinylated intermediates; similarly the acetylase branch utilizes acetyl-CoA to produce acetylated intermediates.

2015 November 7, “Identification of Small-Molecule Inhibitors against Meso -2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyzes the formation of succinate esters


xylulokinase

en-noun

xylulokinase (countable and uncountable, plural xylulokinases)

(biochemistry) A transferase enzyme that catalyzes the chemical reaction ATP + D-xylulose ⇌ ADP + D-xylulose 5-phosphate.


automodification

automodification (usually uncountable, plural automodifications)

(biochemistry) The modification of a protein by the protein itself.


glycosulfatase

(biochemistry) Any enzyme that catalyses the removal of sulfate from a glycoprotein


inulobiose

The inulobiose produced was measured by HPLC assay method.

2015 November 11, “Identification of a Novel Di-D-Fructofuranose 1,2’:2,3’ Dianhydride (DFA III) Hydrolysis Enzyme from Arthrobacter aurescens SK8.001”, in PLOS ONE, →DOI:

(biochemistry) The disaccharide D-fructosyl-2,1-alpha-D-fructose


exoface

Guided by existing SAR and molecular modeling (Fig 2A ), a Lys, Nε-acetylated Lys (Lys-Ac), and LysPEG20L scan at several select positions was undertaken on the non-binding exoface of PN-2171, a close analog of PN-2519 (sequence shown in S1 Table ).

2015 November 11, “Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo”, in PLOS ONE, →DOI:

(biochemistry) The external surface of a coiled protein


virokine

(biochemistry) Any of a group of proteins, similar to cytokines, that are produced by the action of some DNA viruses


oleogustus

Coined in 2015 by researchers at Purdue University, Indiana, USA, from oleo- (“oil”) and Latin gustus (“taste”).

2015, C. A. Running, B. A. Craig, R. D. Mattes, Oleogustus: The unique taste of fat, Oxford University Press:

(biochemistry, neologism) A proposed basic taste sensation triggered by fatty acids.


amylomaltase

On the other hand, Kotoński and Sobiech [14 ] found a lower amylomaltase activity in the red and white muscles of carp during winter, when compared to that in summer.

2015 November 12, “The Activity of Neutral α-Glucosidase and Selected Biochemical Parameters in the Annual Cycle of Breeding Carp ( Cyprinus carpio L.)”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyzes the transglycosylation of maltose or maltodextrins


prosequence

(biochemistry) A part of a protein that is present in this protein's inactive form but is removed during activation. It is usually required for protein folding or maintenance.


protelomerase

The parental pDNA (Fig 3) is composed of an^([sic]) eukaryotic expression cassette flanked by two multi-target sites, called "Super Sequence" (SS), acting as recognition sites for PY54 bacteriophage derived Tel protelomerase.

2015 November 13, “Physical Characterization of Gemini Surfactant-Based Synthetic Vectors for the Delivery of Linear Covalently Closed (LCC) DNA Ministrings”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that generates and protects "hairpin" telomeres


polyglutamylase

polyglutamylase (countable and uncountable, plural polyglutamylases)

Tubulin tyrosine ligase-like (TTLL) proteins show polyglutamylase activity for tubulin in mammalian cells.

2015 November 13, “Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles”, in PLOS ONE, →DOI:

(biochemistry) Any enzyme that catalyzes polyglutamylation.


endopolygalacturonase

(biochemistry) Any endocytic polygalacturonase


azurocidin

The human met-ase locus contains granzyme M, proteinase 3, N-elastase, azurocidin, NSP-4 and complement factor D (CFD).

2015 November 17, “Granule Associated Serine Proteases of Hematopoietic Cells – An Analysis of Their Appearance and Diversification during Vertebrate Evolution”, in PLOS ONE, →DOI:

(biochemistry) Any of a group of cationic antimicrobial proteins that bind heparin


somatolactin

(biochemistry) A protein related to somatotropin and prolactin


muskelin

muskelin (countable and uncountable, plural muskelins)

Alterations to muskelin expression levels altered attachment to TSP-1 in association with subtle changes to the organization of focal contacts [53 ].

2015 November 17, “Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas”, in PLOS ONE, →DOI:

(biochemistry) An intracellular protein that acts as a mediator of cell spreading


pentagalloylglucose

Interestingly, the patient dosed BID with the highest tumor concentration was also taking grape seed oil, which contains pentagalloylglucose, an ABCB1 inhibitor [21 ].

2015 November 17, “Lapatinib Plasma and Tumor Concentrations and Effects on HER Receptor Phosphorylation in Tumor”, in PLOS ONE, →DOI:

(biochemistry) The ester of glucose with five molecules of gallic acid


endoperoxidase

COX called also as prostaglandin endoperoxidase synthase is a membrane—bound hemoprotein and glycoprotein enzyme that catalyzes conversion of cell membrane phospholipids, involved in the synthesis of prostanoids comprising: prostaglandin (PG), prostacyclin (PGI) and the thromboxanes (TXA) and exists as 3 isoforms (COX-1, -2 and -3).

2015 November 26, “The Influence of Prolonged Acetylsalicylic Acid Supplementation-Induced Gastritis on the Neurochemistry of the Sympathetic Neurons Supplying Prepyloric Region of the Porcine Stomach”, in PLOS ONE, →DOI:

(biochemistry) Any peroxidase that is associated with an endoperoxide


phosphopantetheinylate

From phosphopantetheinyl + -ate (“salt or ester”).

af

(biochemistry) Any salt or ester of phosphopantetheine.


phosphopantetheinylate

en-verb

phosphopantetheinylate (third-person singular simple present phosphopantetheinylates, present participle phosphopantetheinylating, simple past and past participle phosphopantetheinylated)

phosphopantetheinylates (present singular third-person)
phosphopantetheinylating (participle present)
phosphopantetheinylated (participle past)
phosphopantetheinylated (past)

From phosphopantetheinyl + -ate (verb-forming suffix).

af

It is a broad spectrum PPTase which is able to phosphopantetheinylate the ACP components of both cytosolic and mitochondrial FAS systems, as well as the aminoadipate semialdehyde dehydrogenase, associated with lysine degradation.

2015 November 26, “Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target”, in PLOS ONE, →DOI:

(biochemistry) To react with phosphopantetheine.


iodinase

en-noun

iodinase (countable and uncountable, plural iodinases)

(biochemistry) Synonym of thyroperoxidase


membrane protein

membrane protein (countable and uncountable, plural membrane proteins)

2000. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Section 3.4, Membrane Proteins. Available from: http://www.ncbi.nlm.nih.gov/books/NBK21570/
Associated with each membrane is a set of membrane proteins that enables the membrane to carry out its distinctive activities.

Membrane proteins, such as receptors, ion channels, and transporters, comprise nearly 30% of all proteins in eukaryotic cells.

2015, Liszewski K, “Dissecting the Structure of Membrane Proteins”, in Genetic Engineering & Biotechnology News, volume 35, number 17, Mary Ann Liebert, page 1:

(biochemistry) A protein that is associated with a biological membrane; association typically refers to either the ability to copurify membrane lipids with said protein or the ability to visualize a physical association in situ.

membránfehérje

a protein that is associated with a biological membrane


phosphoform

(biochemistry) The phosphorylated form of a protein


villikinin

(biochemistry) A hypothetical peptide hormone, conjectured to be released from the duodenal mucosa after a meal and to stimulate villous motility.


carnocin

(biochemistry) A particular bacteriocin produced by the bacterium Carnobacterium piscicola.


sactipeptide

(biochemistry) A kind of peptide containing intramolecular linkages between the sulfur of cysteine residues and the alpha carbon of another residue in the peptide.


micrometabolite

(biochemistry) Any metabolite that is present in very small amounts


isoglobotriose

OPLS regression analysis positioned against the growth rate of one cub tentatively inferred a correlation with changes in the abundance of a trisaccharide, isoglobotriose, previously observed to be a major oligosaccharide in ursid milks.

2015 December 3, “Changes in the Milk Metabolome of the Giant Panda ( Ailuropoda melanoleuca ) with Time after Birth – Three Phases in Early Lactation and Progressive Individual Differences”, in PLOS ONE, →DOI:

(biochemistry) An isomer of globotriose found in the milk of some bears


neurotrypsin

The generation and genotyping of neurotrypsin KO mice has been previously described [22 ].

2015 December 3, “C-Terminal Fragment of Agrin (CAF): A Novel Marker for Progression of Kidney Disease in Type 2 Diabetics”, in PLOS ONE, →DOI:

(biochemistry) A serine peptidase stored in presynaptic nerve endings


gangliotetraose

Taking advantage of the known biochemistry of ganglioside biosynthesis and degradation, we explored the potential for enhancing GM1 levels in the brain by intracranial administration of VCS sialidase, which cleaves the glycosidic linkages between terminal sialic acids of complex gangliotetraose gangliosides GD1a, GD1b, and GT1b, and GQ1b to yield increased levels of GM1 and the potential for this enzyme to exert a neuroprotective effect in the MPTP mouse model of Parkinsonism.

2015 December 3, “Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson’s Disease”, in PLOS ONE, →DOI:

(biochemistry) The tetraose sugar component of a ganglioside.


monosialylated

In plasma, apoC-III exists in non-sialylated (apoC-III 0a without glycosylation and apoC-III 0b with glycosylation), monosialylated (apoC-III 1 ) or disialylated (apoC-III 2 ) proteoforms.

2015 December 4, “The Association of Human Apolipoprotein C-III Sialylation Proteoforms with Plasma Triglycerides”, in PLOS ONE, →DOI:

(biochemistry) sialylated with a single sialic acid residue


metalloendoprotease

Following fertilization, ZP2 undergoes proteolytic cleavage by an oocyte-specific astacin-like metalloendoprotease, first reported as ovastacin (citation), released from the cortical granules, and sperm no longer bind to mouse embryos [22 ].

2015 December 4, “Melamine Impairs Female Fertility via Suppressing Protein Level of Juno in Mouse Eggs”, in PLOS ONE, →DOI:

(biochemistry) any endoprotease that is a metalloenzyme


transrenal

Recently, biomarkers such as Interferon-γ-inducible protein 10 (IP-10) have been shown to be non-specific for TB [7 ] and transrenal DNA has been used for extrapulmonary-TB diagnosis [8 –9 ].

2015 December 4, “Estimation of D-Arabinose by Gas Chromatography/Mass Spectrometry as Surrogate for Mycobacterial Lipoarabinomannan in Human Urine”, in PLOS ONE, →DOI:

(biochemistry, of nucleic acid) extracellular urinary


neuricity

(biochemistry, archaic) Nervous energy or force, regarded as a property inherent in the nerves of the body.


reagin

reagin (countable and uncountable, plural reagins)


checkpoint protein

checkpoint protein (plural checkpoint proteins)

(biochemistry) A protein that halts a cellular process until certain other processes are complete


refoldase

(biochemistry) Any enzyme that catalyzes refolding of a protein


immunocheckpoint

Non-antigen-specific immunotherapies such as immunocheckpoint blockades have been shown to be effective in the treatment of advanced melanoma.

2015 December 8, “Investigation of FOXM1 as a Potential New Target for Melanoma”, in PLOS ONE, →DOI:

(immunology, biochemistry) A checkpoint protein on T cells


hemocoagulase

The present study found that patients with postoperative fibrinogen deficiency experienced more operative blood loss and a higher rate of postoperative intracranial hematoma, and they were given more blood transfusions, more plasma transfusions, and were administered larger doses of hemocoagulase compared with patients without postoperative fibrinogen deficiency.

2015 December 12, “Risk Factors for Postoperative Fibrinogen Deficiency after Surgical Removal of Intracranial Tumors”, in PLOS ONE, →DOI:

(biochemistry) An enzyme, typically isolated from snake venom, that catalyzes the coagulation of the blood and therefore stops bleeding


Bowman-Birk protease inhibitor

Bowman-Birk protease inhibitor (plural Bowman-Birk protease inhibitors)

Bowman-Birk protease inhibitors (plural)

(biochemistry) Any of a family of eukaryotic proteinase inhibitors found mainly in the seeds of legumes and in cereal grains.


cateslytin

In this context, we suppose that cateslytin with its net positive charge of +5 might also interact with hemagglutinin B. In our case, blocking the P.

2015 December 15, “Antibacterial Peptide-Based Gel for Prevention of Medical Implanted-Device Infection”, in PLOS ONE, →DOI:

(biochemistry) A peptide, derived from a chromogranin, that shows an antimicrobial action


glycoepitope

(biochemistry, immunology) A carbohydrate epitope


procathepsin

The activity was estimated by reducing the incubation time to 2 min to avoid procathepsin L activation [17 ,19 ].

2015 December 17, “An Active 32-kDa Cathepsin L Is Secreted Directly from HT 1080 Fibrosarcoma Cells and Not via Lysosomal Exocytosis”, in PLOS ONE, →DOI:

(biochemistry) Any of a family of proteins that are involved in the production of cathepsins


rhamnopyranoside

(biochemistry) Any pyranoside derived from rhamnose.


multimethylation

For instance, PTMs such as lipoylation, glycosylation, phosphorylation and SUMOylation can have a high impact on host immune modulation during Ehrlichia muris [57 ], Ehrlichia chaffeensis [58 ] and Anaplasma phagocytophilum [59 ] infections and, multimethylation can lead to different levels of virulence in R.

2015 December 22, “Comparative Proteomic Profiling of Ehrlichia ruminantium Pathogenic Strain and Its High-Passaged Attenuated Strain Reveals Virulence and Attenuation-Associated Proteins”, in PLOS ONE, →DOI:

(biochemistry) methylation at multiple sites


intradiol

Local oxygen levels may be further reduced by the up regulation of a putative secreted intradiol dioxygenase (PAU_03890), as this class of enzyme utilise molecular oxygen.

2015 December 18, “From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity”, in PLOS ONE, →DOI:

(biochemistry) Between the carbon atoms that carry the two hydroxyl groups of a diol


dickkopf

Borrowed from German Dickkopf (“stubborn person”, literally “thick head”), from the fact that Dickkopf-related protein 1 (DKK1), one of the dickkopf proteins, was found to be required for head formation in embryos. The word was coined by Andrei Glinka, Wei Wu, Hajo Delius, A. Paula Monaghan, Claudia Blumenstock, and Christof Niehrs in a 1998 article published in Nature: see the quotation.

bor

Here we describe dickkopf-1 (dkk-1), which encodes Dkk-1, a secreted inducer of Spemann's organizer in Xenopus and a member of a new protein family.

[1998 January 22, Andrei Glinka et al., “Dickkopf-1 is a Member of a New Family of Secreted Proteins and Functions in Head Induction”, in Nature, volume 391, number 6665, London: Nature Research, →DOI, →ISSN, →OCLC, abstract, page 357:

Some of the factors tested included: angiopoietin like protein 7 (ANGLPT7), epidermal growth factor (EGF), fibroblast growth factor 2 (FGF2), transforming growth factor beta 2 (TGF β 2), platelet derived growth factor b (PDGFB), and dickkopf related protein 2 (DKK2).

2015 December 22, Kathryn L. McCabe et al., “Efficient Generation of Human Embryonic Stem Cell-derived Corneal Endothelial Cells by Directed Differentiation”, in PLOS ONE, volume 10, number 12, San Francisco, Calif.: PLOS, →DOI, →ISSN, →OCLC, article number e0145266:

Oncogenic mutations in the human genome disable of the 'β-catenin-destroyer complex' and delete the dickkopfs.

2016, Joseph G. Sinkovics, “Eukaryotic Single Cells and the First Cell Communities Then and Now”, in RNA/DNA and Cancer, Cham, Switzerland: Springer, →DOI, →ISBN, page 81:

(biochemistry) Any of a family of glycoproteins that are involved in the development of the embryo.

British Journal of Pharmacology
British Pharmacological Society
DKK1
Wiley-Blackwell

Dickkopf-proteiini

any of a family of glycoproteins that is involved in the development of the embryo


deacylase

They exhibit a diverse range of functional categories that include porin, transporter, adhesin, lipase, protease, deacylase, pore-forming toxin, and assembly factors [2 ,3 ].

2015 December 23, “PredβTM: A Novel β-Transmembrane Region Prediction Algorithm”, in PLOS ONE, →DOI:

(biochemistry) Any hydrolase that removes an acyl group by hydrolysis


rubipodanin

Fortunately, a new cyclic hexapeptide, rubipodanin A ( 1 ), which is the first identified natural N-desmonomethyl RA, together with six known RAs ( 2–7 ) were obtained.

2015 December 23, “Rubipodanin A, the First Natural N -Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N 9 -Methyl Group in the Conformation and Bioactivity”, in PLOS ONE, →DOI:

(biochemistry) Any of a family of cyclic peptides found in the madder Rubia podantha


protosite

To expand the distribution of plant resources containing RAs and explore the functional role of N-methylated amino acids in natural RAs in the maintenance of the conformation and bioactivity, we structurally and pharmacologically investigated interesting RAs using the TLC cyclopeptide protosite detection method with ninhydrin [23 ] from R.

(biochemistry) Any part of a biomolecule that has the potential to be a site for the attachment of another one


transcuprein

Albumin (about 69 kDa) has a very high affinity Cu(II) site at its N-terminus (Kd about 10−12 M) in most mammals; and transcuprein, which in humans is alpha-2-macroglobulin, has an even higher Cu affinity.

2016 March 3, “Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells”, in PLOS ONE, →DOI:

(biochemistry) A small protein with a specific role in plasma copper transport.


thermoswitch

This appears to be the first purely computational design of functional RNA thermoswitches, and certainly the first purely computational design of functional thermo-IRES elements.

2016, Juan Antonio Garcia-Martin, Ivan Dotu, Javier Fernandez-Chamorro, Gloria Lozano, Jorge Ramajo, Encarnacion Martinez-Salas, Peter Clote, “RNAiFold2T: Constraint Programming design of thermo-IRES switches”, in arXiv:

(biochemistry) A form of riboswitch incorporating a thermosensor and thus responsive to temperature changes.


inulosucrase

(biochemistry) Any transferase that catalyzes the transfer of a fructose moiety from sucrose to inulin


ferritinophagy

Alternatively, the turn over of ferritin by the process of ferritinophagy could be modified in the absence of CFTR [45, 46 ].

2015 December 29, “Iron Homeostasis and Inflammatory Status in Mice Deficient for the Cystic Fibrosis Transmembrane Regulator”, in PLOS ONE, →DOI:

(biochemistry) The metabolism of ferritin


homoglucan

Dextran, a homoglucan produced by Leuconostoc mesenteroides, has been cited as the primary polysaccharide associated with sugarcane deterioration.

2015 December 29, “Diverse Exopolysaccharide Producing Bacteria Isolated from Milled Sugarcane: Implications for Cane Spoilage and Sucrose Yield”, in PLOS ONE, →DOI:

(biochemistry) A homopolysaccharide composed of glucose moieties


phosphodonor

Their K 1/2 values scaled inversely with the aggregate lengths of their connecting segment between Tsr1 and Tsr2: the longest linker (546~551/L-6) produced the most sensitive response (K 1/2 = 55 μM); the shortest (517~551/L-4) failed to respond to serine, but evinced high kinase activity upon potassium cyanide challenge, which depletes cellular ATP, the phosphodonor for the CheA autophosphorylation reaction (see Methods ).

2015 December 29, “Chemotactic Signaling by Single-Chain Chemoreceptors”, in PLOS ONE, →DOI:

(biochemistry) Any substance that donates a phosphoryl group


undecaheme

Such preferential orientation may be deduced, for example, from recent X-ray diffraction data of undecaheme cytochrome crystalized in the presence of soluble Fe(III) chelates [23 ,26 ].

2015 December 29, “In Situ Analysis of a Silver Nanoparticle-Precipitating Shewanella Biofilm by Surface Enhanced Confocal Raman Microscopy”, in PLOS ONE, →DOI:

(biochemistry, in combination) Eleven heme groups in a molecule


despeciated

(biochemistry) Of a serum: modified so that it is no longer species-specific, to avoid triggering allergic reactions.


myoneurin

In that essence, the effect of such SNPs can be mediated through one of the other genes in 3q26 locus that were found to actually play a role in controlling expression either by activating or repressing the transcription of various genes such as encoding myoneurin (MYNN) including telomerase.

2016 January 1, “Associations of TERC Single Nucleotide Polymorphisms with Human Leukocyte Telomere Length and the Risk of Type 2 Diabetes Mellitus”, in PLOS ONE, →DOI:

(biochemistry) Any of a family of zinc finger proteins whose members have been implicated in regulatory functions of gene expression


royalisin

(biochemistry) A defensin-like peptide found in royal jelly.


cytochemically

(biochemistry) With reference to, or by means of cytochemistry


physiocrine

Prior work showed that the asparaginyl-tRNA synthetase (BmAsnRS) of Brugia malayi, an etiological agent of lymphatic filariasis, acts as a physiocrine that binds specifically to interleukin-8 (IL-8) chemokine receptors.

2016 January 12, “Brugia malayi Asparaginyl - tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis”, in PLOS ONE, →DOI:

(biochemistry) Any of a family of physiologically-active cytokines


pneumolysoid

To our best knowledge, a validation of pneumolysoid B as a replacement for the PLY antigen in the EIA to detect anti-PLY IgG has never been published.

2016 January 14, “Efficacy of PPV23 in Preventing Pneumococcal Pneumonia in Adults at Increased Risk – A Systematic Review and Meta-Analysis”, in PLOS ONE, →DOI:

(biochemistry) Any of a group of recombinant mutant proteins related to pneumolysin.


trimannoside

ConA is a plant lectin, which binds avidly to the trimannoside core of N-glycans, bisected hybrid-type N-glycans and to a lesser extent to complex-type biantennary N-glycans, whereas highly branched N-glycans will not bind or bind not as tightly [15 ].

2016 January 14, “Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased β1,6- N -Glycosylation and Increased Susceptibility to Galectin-3 Binding”, in PLOS ONE, →DOI:

(biochemistry) Any glycoside having three mannose groups


EGFR

epidermal growth factor receptor
w:epidermal growth factor receptor

(biochemistry) Initialism of epidermal growth factor receptor.