hydrosulphosol

A former trademark of E. C. Lientz & Co., Inc.

Hydrosulfosol in oil with gentle pressure dressings may promote healing after severe burns of the eye. For conjunctival and corneal burns, 0.5% cortisone is used locally on dressings and, after the dressings are omitted, four times daily.

1954 February 15, William B. Clark, Edwin B. Dunphy, S. Rodman Irvine, Lawrence T. Post, Derrick T. Vail, “Early Treatment of Eye Injury”, in Modern Medicine, volume 22, number 4, Minneapolis, Minn.: Modern Medicine Publications, Inc., page 146:

(pharmacology, dated) Synonym of calsulfhydryl.


calsulfhydryl

Since 1942 several clinical investigations have been published describing the increased healing rate of corneal wounds treated with calsulfhydryl (Hydrosulphosol¹). […] The present study was undertaken therefore to evaluate the effect of calsulfhydryl on a controlled series of rabbits corneas injured by abrasion or by acid or alkali burns.

1953 December, Robert E. Rocknem, “Evaluation of wounds of the rabbit cornea treated with calsulfhydryl (Hydrosulphosol)”, in Archives of Ophthalmology, volume 50, number 6, →DOI, page 696:

(pharmacology, dated) A glycerol–water solution containing calcium polysulfides and calcium thiosulfates, formerly used for the treatment of chemical burns of the eye and other conditions.


paroxysmal atrial tachycardia

en-noun

paroxysmal atrial tachycardia (plural paroxysmal atrial tachycardias)

(cardiology) An episode of arrhythmia that begins and ends abruptly.


atrial tachycardia

atrial tachycardia (plural atrial tachycardias)

(cardiology) A type of heart rhythm problem in which the heart's electrical impulse comes from an ectopic pacemaker in the upper chambers.


black fungus

black fungus (countable and uncountable, plural black funguses or black fungi)

black funguses (plural)
black fungi (plural)


auricular fibrillation

auricular fibrillation (countable and uncountable, plural auricular fibrillations)

atrial fibrillation
atrial fibrillation#English

(medicine) Synonym of atrial fibrillation


Other

Semantic loan from French Autre, principally after French psychoanalyst Jacques Lacan (also as grand Autre) and philosopher Emmanuel Levinas.

In its most fundamental dimension, sacrifice is a “gift of reconciliation” to the Other, destined to appease its desire. Sacrifice conceals the abyss of the Other’s desire, more precisely: it conceals the Other’s lack, inconsistency, “inexistence,” that transpires in this desire. Sacrifice is a guarantee that “the Other exists” […]

1992, Slavoj Žižek, Enjoy Your Symptom! Jacques Lacan in Hollywood and Out, →ISBN, page 56:

The transformations of writing bear an ethical as well as an aesthetic or literary significance; writing implies orientation towards the Other in the midst of which a renewal of the self becomes possible.

2006, Lisa Guenther, The Gift of the Other: Levinas and the Politics of Reproduction, →ISBN, page 123:

Critiquing the Western philosophical tradition of privileging the autonomy of the ‘I’, in which he uses Heidegger as exemplar, Levinas provocatively argues that the ‘I’ ultimately exists to be responsible for the Other – a responsibility based not on reciprocity (whether the Other behaves in accordance to expectations of the ‘I’) but on an asymmetrical and infinite kind of responsibility.

2015, Jonathan Corpus Ong, The Poverty of Television: The Mediation of Suffering in Class-Divided Philippines, →ISBN, page 17:

(philosophy, psychoanalysis) Radical alterity or otherness conceived or reified as a separate entity; “other people” altogether in their difference from oneself.


Purkinje layer

Named after Czech anatomist Jan Evangelista Purkyně (1787–1869).

named-after

(anatomy) The narrow layer of Purkinje cells in the cerebellar cortex.


radiendocrinology

*From radi- (radium, radiation) + endocrinology.

It considers those new findings with reference to the electronic nature of the body, which paved the way for Dr. Steinach’s radiation-rejuvenation treatment, and laid the foundation for the newer science of Radiendocrinology.

1923, Rubin, Herman H., The new science of radiendocrinology in its relation to rejuvenation: based on the radiation technique of Dr. Eugen Steinach of Vienna, page 5:

(rare, obsolete, medicine) The study of radiative endocrine interactions and their effects upon vitality.


superimmunity

Under these conditions, inoculations with the virus cause a reaction fever without any internal symptoms of the disease and in this way generally, after 3 inoculations, superimmunity is assured against natural infection which lasts during the whole dairy period for milch cows.

1921, The Agricultural Gazette Vol-8 (1921), page 489:

The goal of cloning superimmunity to the limited number of phages that attack some S. cremoris strains, in particular, is attractive. A prerequisite, however, is a concerted study of the biochemistry and molecular biology of phage repressor systems in the lactic streptococci.

Our results are consistent with those obtained by other groups screening camelid-derived libraries, where an impressive diversity in the Nb nucleotide sequence, specificity and neutralizing capacity was found, especially after successive immunizations to promote the development of superimmunity.

2023 March 14, “Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants”, in National Library of Medicine:

(medicine) The state of being exceptionally resistant to disease.


PLHIV

(medicine) Initialism of people living with HIV.


MBSR

(medicine, psychology) Abbreviation of Mindfulness-Based Stress Reduction. (an eight-week evidence-based program to assist people with stress, anxiety, depression and pain.)


odontoplasty

(dentistry) A procedure that adjusts a tooth's size, shape or length through the selective removal of small amounts of enamel


paraglossia

(medicine, rare) Inflammation of the muscles and connective tissue under the tongue.


pink eye

en-noun

pink eye (countable and uncountable, plural pink eyes)

Some of the migrants, including pregnant women and small children, are ill with colds, pink eye or Covid-19, leaving volunteers and city workers scrambling to find them health services.

2023 May 10, Julie Bosman, “Open-Armed Chicago Feels the Strains of a Migrant Influx”, in The New York Times, →ISSN:

(pathology) Alternative spelling of pinkeye


Diogenes syndrome

(psychiatry, psychology) A disorder characterized by extreme self-neglect, domestic squalor, social withdrawal, apathy, compulsive hoarding of garbage or animals, and a lack of shame.


Fordyce spot

Named after the American dermatologist John Addison Fordyce who described them in 1896.

(dermatology, chiefly in the plural) A sebaceous gland which appears as a yellow-white bump on the skin, most commonly on the lips, cheeks, gums, or genitalia.


osteorrhaphy

Good results are seldom obtained by wiring the bone fragments, i. e., a uniting of the fractured pieces by means of wire sutures (osteorrhaphy). Wire sutures generally hamper a normal healing of the fracture, because they act as a foreign body, delay consolidation and quite often lead to necrosis and sequestrum.

1944, Filip Pålsson, “Palsson, F. (1944). Orthopaedic Treatment of Fractures of the Lower Jaw in Children: With Special Reference to Two Cases treated in Children under Two Years of Age”, in Acta Odontologica Scandinavica, volume 5, number 2, →DOI, page 33:

At our hospital, the temporal approach is most frequently employed, but osteorrhaphy by exposing the fracture site is also performed depending on the indications.

1987, Yoshiharu Kawano, “Three Dimensional Analysis of the Face in Respect of Zygomatic Fractures and Evaluation of the Surgery with the Aid of Moiré Topography”, in Journal of Cranio-Maxillo-Facial Surgery, volume 15, →DOI, page 72:

Ultra-high-molecular-weight polyethylene (UHMWPE) is commonly used as the load-bearing materials of bone implants such as hip prosthesis, sutures in osteorrhaphy, and synthetic ligaments.

2017 October 20, Chengchong Ai, Dandan Sheng, Jun Chen, Jiangyu Cai, Siheng Wang, Jia Jiang, Shiyi Chen, “Surface modification of vascular endothelial growth factor-loaded silk fibroin to improve biological performance of ultra-high-molecular-weight polyethylene via promoting angiogenesis”, in International Journal of Nanomedicine, volume 12, →DOI, page 7737:

(rare, medicine) Synonym of osteosuture.


breakfast, lunch and dinner

The typical clinical finding is several erythematous papules or urticarial lesions grouped together. Often three appear in a row (breakfast, lunch and dinner), but of course the bedbug does not keep count and both solitary bites and many lesions are common.

2012, Otto Braun-Falco, Gerd Plewig, Helmut Heinrich Wolff, Walter H.C. Burgdorf, Dermatology, second edition, Springer Science & Business Media, →ISBN, page 364:

(dermatology, informal) A group of three bedbug bites appearing together.


PESE

post-exertional symptom exacerbation
w:post-exertional malaise

(pathology) Initialism of post-exertional symptom exacerbation.


SCANDAL

(biology, evolution, taxonomy, pathology) Acronym of speciated by cancer development animals.


SCANDAL

Coordinate term: transmissible cancer

(biology, evolution, taxonomy, pathology) Ellipsis of SCANDAL taxon; a species or taxon which speciated due to the SCANDAL process.

SCANDAL taxon

Coordinate term: transmissible cancer

(biology, evolution, taxonomy, pathology) Ellipsis of SCANDAL process; the mechanism for speciation through cancer cells becoming independent of the originating creature, and living on.


gastrocnemiosemimembranosus bursa

(anatomy) A bursa located near the gastrocnemius and the semimembranosus muscle.


menotoxin

(historical, medicine) According to a now-debunked theory of the early 20th century, a toxic substance that builds up in the body and is excreted during menstruation.


microposthia

From micro- + Ancient Greek πόσθη (pósthē) + -ia.

af

(medicine, urology) The condition where the foreskin of the penis does not cover the glans.


macroposthia

From macro- + Ancient Greek πόσθη (pósthē) + -ia.

(medicine, urology) A medical condition where the foreskin of the penis extends well past the end of the glans.


neurosthenia

From New Latin, from Ancient Greek νεῦρον (neûron) + Ancient Greek σθένος (sthénos); by surface analysis, neuro + sthenia.

(medicine, archaic) Strong reaction or overreaction of a nerve to a stimulus.


neurosthenia

From mistaken rebracketing of neurasthenia (whose valid surface analysis is neur- + asthenia) as if it were prefixed with neuro-, by false analogy with most other ISV compounds beginning with the syllable neur- + /ə/ (which are thus prefixed). The error is not rare, but it invites proscription because the -a- syllable in neurasthenia corresponds to the negation of strength, that is, to weakness (of constitution or affect); by surface analysis, it is equivalent to a- ("without"/"opposite"), the difference between strength and weakness.

(medicine, proscribed) Misconstruction of neurasthenia.


micropathic

Lillie has shown that the presence of the virus in various organs was accompanied by micropathic changes.

1935, University of Michigan. University Hospital, University Hospital Bulletin - Volumes 1-8, page 84:

The combined effects of tissue ischemia secondary to micropathic angiopathy and of eosinophil-derived neurotoxins have been considered to be of pathobiologic significance (30).

1990, Proceedings of the National Academy of Sciences of the United States of America, page 8650:

They demonstrated persistent proteinuria and eventually developed evidence of micropathic hemolytic anemia; however, no decline in renal function was noted.

2016 June, Gwenalyn Garcia, Jean Paul Atallah, “Antineoplastic agents and thrombotic microangiopathy”, in Journal of Oncology Pharmacy Practice, volume 23, number 2:

(medicine) Involving pathology that manifests at or results from changes at a microscopic level.


burn center

(medicine) A hospital specializing in the treatment of burns.


TWI

Coordinate term: TDI

In May 2001 an expert committee has decided that tolerable doses should be expressed as tolerable weekly intake (TWI) and established TWI = 14 pg/kg.

2005, Przemysław Mastalerz, The True Story of DDT, PCB, and Dioxin, Wydawnictwo Chemiczne, →ISBN, page 91:

tolerable weekly intake
w:tolerable weekly intake

(toxicology) Initialism of tolerable weekly intake.


PTMI

(toxicology) Initialism of provisional tolerable monthly intake.


PTDI

(toxicology) Initialism of provisional tolerable daily intake.


PTWI

(toxicology) Initialism of provisional tolerable weekly intake.


hemangiopericyte

Since the production of renin has been identified in the brain, blood vessel walls, adrenal, ovary and testis in addition to the kidney, extra-renal renin secreting tumors have been reported in tumors which developed in the genital organs, the hemangiopericytes of the eye and the adrenal.

1991, Koichi Kowai et al., “A Case of Renin Producing Leiomyosarcoma Originating in the Lung”, in Endocrinol Jpn., volume 38:

(anatomy, rare) An adventitial pericyte, typically of a capillary.


drug holiday

(pharmacology) A time period when a patient ceases taking medication.


(organic chemistry, pharmacology) Synonym of carfentanil


Wildnil

(organic chemistry, pharmacology) Synonym of carfentanil (trade name)


paracusia acris

(medicine, otolaryngology) An intense and incessant acuity of hearing.


paracusia willisii

Named after Thomas Willis, a founder of the Royal Society and anatomist in 1672.

(medicine, otolaryngology) A clinical symptom observed in patients suffering from bilateral conductive deafness involving a sensation wherein it is possible to hear more easily in the midst of a noisy environment rather than in a relatively quiet one.


cryocompression

(medicine) A therapy involving the simultaneous use of compression and cryotherapy.


Champy technique

(medicine) An approach to mandible fracture stabilization involving a single monocortical miniplate.


Champy plate

(medicine) The monocortical miniplate used in the Champy technique.


Champy's line

(medicine) An ideal line of osteosynthesis for mandible fractures, used in the Champy technique.


iDNA

Such iDNAs are flanked by common 10–20 bases long → primer sequences (F [forward] and R [reverse] primers for amplification in a conventional → polymerase chain reaction) […]

2015, Günter Kahl, The Dictionary of Genomics, Transcriptomics and Proteomics, volume 1, John Wiley & Sons, →ISBN, page 1074:

(genetics) Initialism of information DNA.


sEPSC

spontaneous excitatory postsynaptic current#English

(neurology) Abbreviation of spontaneous excitatory postsynaptic current.


MCH

mean corpuscular hemoglobin
mean corpuscular hemoglobin#English

(hematology) Initialism of mean corpuscular hemoglobin.

MCHC

mean corpuscular hemoglobin concentration


direct repeat

(biology, genetics) A type of genetic sequence that consists of two or more repeats of a specific sequence.


pseudomucinous

(medicine) Of or pertaining to pseudomucin.


SLT

en-noun

SLT (countable and uncountable, plural SLTs)

(surgery) Initialism of selective laser trabeculoplasty.


maternity test

(law, genetics) A test designed to determine the biological relationship between an alleged mother and a child.


Miller-Abbott tube

Miller-Abbott tube (plural Miller-Abbott tubes)

Invented by William Osler Abbott and Thomas Grier Miller.

(medicine) A device used to treat obstructions in the small intestine through intubation, consisting of two tubes, one for water and one to inflate a balloon in the duodenum.


trapdoor effect

(surgery) The formation of a trapdoor deformity.


trapdoor deformity

trapdoor deformity (plural trapdoor deformities)

(surgery) An outward bulging of the tissue in a curved scar, caused by concentric retraction.


capsule of lens

(anatomy) The transparent membrane that surrounds the entire lens of the eye.


mife

The miso/mife combination is becoming increasingly popular: In 2011, it accounted for 36 percent of all abortions before nine weeks of gestation, and it’s often considered the gold standard of medication abortion, with an estimated success rate that is nearly 10 percent higher than using miso alone (92 to 95 percent and 80 to 85 percent, respectively).

2014 June 27, Erica Hellerstein, “The Rise of the DIY Abortion in Texas”, in The Atlantic:

(pharmacology, informal) Clipping of mifepristone.


LRL

Coordinate term: URL

(medicine, statistics) Initialism of lower reference limit.


obliterative bronchiolitis

bronchiolitis obliterans
bronchiolitis obliterans#English

(pathology) Synonym of bronchiolitis obliterans.


cloverleaf model

cloverleaf model (plural cloverleaf models)

(genetics) A model that depicts the molecular structure of tRNA, showing how its chain consists of two "business ends" and three arms.


ophthalmomycosis

ophthalmomycosis (countable and uncountable, plural ophthalmomycoses)

(medicine) An eye disease caused by a fungus.


infohazardous

en-adj

infohazardous (comparative more infohazardous, superlative most infohazardous)

more infohazardous (comparative)
most infohazardous (superlative)

(neurology, chiefly science fiction) Being, containing, or pertaining to an infohazard.


antimemetic

antimemetic (comparative more antimemetic, superlative most antimemetic)

more antimemetic (comparative)
most antimemetic (superlative)

From antimeme + -etic or anti- + memetic.

(neurology, sociology, chiefly science fiction) Of, being, containing, or pertaining to antimemes.


ecchordosis physaliphora

(medicine) A benign gelatinous tumor attached to the back of the clivius resulting from left-over notochord.


transbasal

(surgery) from the transcranial extradural anterior to the midline anterior skull base.


norclobazam

(pharmacology) A metabolite of clobazam in which a methyl group has been removed from a nitrogen atom. IUPAC name is 7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione.


trial of scar

Tradition has taught that a previous classical Caesarean section, more than one scar, previous obstructed labour, and contracted pelvis all provide absolute contraindications to a trial of scar.

1988, Christopher Targett, “Caesarean Section and Trial of Scar”, in The Australian and New Zealand Journal of Obstetrics and Gynaecology, volume 28, number 4, pages 249–262:

In a recent UK survey, 95% of consultants responded that they would not allow trial of scar following a classical Caesarean section (Roberts et al 1994).

1995, Geoffrey Chamberlain, editor, Turnbull's Obstetrics, 2nd edition, Churchill Livingstone, →ISBN, page 719:

A trial of scar may be justified in a woman with a previous cesarean section who is currently on HAART, has an undetectable virus and spontaneously goes into labor.

2012, Jyoti Dhar, “A Guide to the Clinical Care of Pregnant Women with HIV”, in Mamatha M Lala, Rashid H Merchant, editors, Principles of Perinatal and Pediatric HIV/AIDS, Jaypee Brothers Medical Publishers (P) Ltd, →ISBN, page 317:

(obstetrics) A labour where a vaginal delivery is attempted in a woman who has had a previous caesarean section.


EHD

epizootic hemorrhagic disease
epizootic hemorrhagic disease#English

(veterinary medicine, agriculture) Initialism of epizootic hemorrhagic disease.


aPDT

en-noun

aPDT (countable and uncountable, plural aPDTs)

photodynamic therapy
photodynamic therapy#English

(medicine) Initialism of antimicrobial photodynamic therapy.


firsocostat

(pharmacology) An acetyl-CoA carboxylase inhibitor drug.


penicillin VK

(pharmacology) Synonym of phenoxymethylpenicillin.


IFG

impaired fasting glucose
w:impaired fasting glucose

(medicine) Initialism of impaired fasting glucose.


ethacizine

myocardial infarction
myocardial infarction

(organic chemistry, medicine) An antiarrhythmic agent used in Russia for the treatment of refractory tachycardia, myocardial infarction, and other ventricular or supraventricular heart arrhythmias.


Licopid

(medicine) An immunomodulatory drug used in some Eurasian and Slavic countries for the treatment of immunodeficiency and other inflammatory conditions.


circulatory shock

circulatory shock (countable and uncountable, plural circulatory shocks)

(medicine) A medical emergency characterized by the inability of the circulatory system to supply enough oxygen to meet tissue requirements.


dry shower

en-verb

dry shower (third-person singular simple present dry showers, present participle dry showering, simple past and past participle dry showered)

dry showers (present singular third-person)
dry showering (participle present)
dry showered (participle past)
dry showered (past)

(medicine) To bathe using cleaning products such as sanitizing wipes or a spray bottle which cleans the skin without the use of water.


HAROLD

(medicine) Acronym of hemispheric asymmetry reduction in older adults.


IUGR

(obstetrics) Initialism of intrauterine growth restriction.


gestational diabetes

(obstetrics) A condition in which a woman without diabetes develops high blood glucose levels during pregnancy.


Türk cell

Originally described by W. Türk in 1907.

(immunology) A cytotoxic lymphocyte that becomes large as a result of antigen stimulation.


Downey cell

Hal Downey wrote about the features of such cells in 1923.


harlequinism

en-noun

harlequinism (usually uncountable, plural harlequinisms)

harlequin-type ichthyosis
harlequin-type ichthyosis#English

(medicine) Synonym of harlequin-type ichthyosis


rheumatoid factor

rheumatoid factor (plural rheumatoid factors)

rheumatoid arthritis
rheumatoid arthritis

(immunology) An autoantibody directed against the Fc fragment of immunoglobulin G (IgG), often elevated in certain conditions including rheumatoid arthritis and Sjögren's syndrome.


bone cancer

bone cancer (countable and uncountable, plural bone cancers)

(oncology) A disease in which abnormal cells multiply without control in the bones.


prostate cancer

prostate cancer (countable and uncountable, plural prostate cancers)

(oncology, pathology) Cancer of the prostate gland.


PPROM

preterm prelabor rupture of membranes
w:preterm prelabor rupture of membranes

rupture of membranes
rupture of membranes#English

(medicine) Initialism of preterm prelabor rupture of membranes or initialism of preterm premature rupture of membranes.


H&NC

H&NC (countable and uncountable, plural H&NCs)

head and neck cancer
w:head and neck cancer

(oncology, pathology) Initialism of head and neck cancer.


radioleukemia

radioleukemia (countable and uncountable, plural radioleukemias)

We have just seen the C57 BI mice are sensitive to the extract of radioleukaemia—as young AkR are sensitive to superinfection with the AkR virus. This fact is not favourable to the proviral hypothesis. However, it does not rule it out if one supposes that the ‘virogenized’ cells may be different from those which the virus cancerizes.

1962, R. Latarjet, J-F. Duplan, L. Chamaillard, P. Monnot, A. Palaysi, “Experiment and discussion on leukaemogenesis by cell-free extracts of radiation-induced leukaemia in mice”, in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, volume 5, number 4, →DOI, page 342:

(oncology, uncommon) Leukemia induced by radiation.


antigen-presenting cell

antigen-presenting cell (plural antigen-presenting cells)

(immunology) a cell that displays antigen bound by major histocompatibility complex (MHC) proteins on its surface.


APH

antepartum haemorrhage
w:antepartum haemorrhage

(obstetrics) Initialism of antepartum haemorrhage.


rhupus

Blend of rheumatoid arthritis + lupus. Coined by Austrian-born American rheumatologist Peter H. Schur in 1971.

coinage

As controls, 34 patients with rheumatoid arthritis and nine patients with rheumatoid arthritis and systemic lupus erythematosus (rhupus) were included. […] In contrast, rheumatoid arthritis and rhupus patients had 30- and 23-fold higher than normal amounts of anti-CCP (p < 0.001, both comparisons).

2008, GN Damián-Abrego, J Cabiedes, AR Cabral, “Anti-citrullinated peptide antibodies in lupus patients with or without deforming arthropathy”, in Lupus, volume 17, number 4, →DOI, page 300:

systemic lupus erythematosus
systemic lupus erythematosus

(pathology) A rare condition characterized by overlapping features of both rheumatoid arthritis and systemic lupus erythematosus.


MCTD

mixed connective tissue disease
mixed connective tissue disease#English

(pathology) Initialism of mixed connective tissue disease.


mixed connective tissue disease

en-noun

mixed connective tissue disease (uncountable)

(pathology) An autoimmune disease characterized by a mix of symptoms of systemic lupus erythematosus (SLE), systemic sclerosis, and polymyositis, associated with elevated levels of anti-U1 RNP antibodies.


SSc

SSc (countable and uncountable, plural SScs)

systemic sclerosis
systemic sclerosis#English

(pathology) Abbreviation of systemic sclerosis.


cortico-subthalamo-pallidal

(anatomy) Relating to the cortex, subthalamus, and globus pallidus.


loric

Coined in 1985 by P. F. Little from the initials of "lambda-origin cosmid".

We describe the construction and use of a cosmid vector, loric, which is derived from the phage lambda origin of replication and appears to be more stable than ColE1-derived cosmids. Loric recombinants can be efficiently packaged in vivo to yield 100-300 micrograms of DNA per liter that is linear and has single-stranded cos ends.

1985 May, P F Little and S H Cross, “A cosmid vector that facilitates restriction enzyme mapping.”, in PNAS, volume 82, number 10, page 3159:

The cosmid vector loric ( 'lambda-origin cosmid' ) is designed to allow rapid mapping of restriction sites in cloned DNAs and thus to facilitate analyses of large regions of chromosomes.

1985, P. H. Pouwels, Cloning Vectors: A Laboratory Manual, page 6:

In order to improve the stability of the recombinant cosmid and increase DNA yield, the ColE replicon was replaced with the lambda phage replicon (Little and Cross, 1985) creating the loric (or 'lambda-origin cosmid') vector.

2005, Anatoly Ruvinsky, Jennifer A. Marshall Graves, Mammalian Genomics, page 69:

(genetics) A cosmid vector derived from the lambda phage replicon.


Dutch-Kentucky syndrome

(medicine) Synonym of trismus pseudocamptodactyly syndrome


Prolene

A trade name, contrived by the product developers and marketers.

(surgery) A brand of synthetic polypropylene, used as a monofilament nonabsorbable suture, in meshes, and in casts.


Bovie

From the Bovie Medical Corporation, named after William T. Bovie (1882-1958), a pioneer of biophysics and electrosurgery, who led the development of the class of device.

genericized trademark
genericized trademark

(surgery, genericized trademark) A tool for electrosurgery, including radiofrequency ablation and electrocautery.


euparathyroidism

(medicine) Healthy parathyroid function, with normal amounts of parathyroid hormone.


second brain

Although our ‘second brain’ doesn't make executive decisions like our actual brain, the two do communicate back and forth via electrical impulses through a pathway of nerves—the gut-brain axis—and this pathway influences our endocrine, immune and neural systems.

2018, Lee Holmes, Supercharge Your Gut: Supercharged Food, Allen & Unwin, →ISBN:

This network can function nearly independently from the brain; indeed, its complexity has earned it the nickname “the second brain.” And just like the brain, it’s made up of two kinds of nervous system cells: neurons and glia.

[2023 November 21, Yasemin Saplakoglu, “In the Gut’s ‘Second Brain,’ Key Agents of Health Emerge”, in Quanta Magazine:

enteric nervous system
enteric nervous system

(anatomy, informal) The enteric nervous system.


kinoid

From (cyto)kine + -oid, modelled on toxoid. Coined by Bernard Bizzini and A. Achour in 1995.

For this purpose, IFN alpha was chemically converted into a biologically inactive, but still immunogenic product, which we termed “kinoid”, reminiscent of that of bacterial toxins which have been transformed into toxoids for vaccination. […] Active “kinoid” immunization should permit to counteract the overproduction of the corresponding cytokine when involved in pathogenesis.

[1995 May 1, Bernard Bizzini, A. Achour, “"Kinoids": the basis for anticytokine immunization and their use in HIV infection”, in Cellular and Molecular Biology (Noisy-le-Grand, France), volume 41, number 3, →PMID, pages 351–356:

We are currently developing IFNα–kinoid (IFN-K) as an alternative treatment for SLE. Kinoids are composed of inactivated cytokines conjugated to a carrier protein, keyhole limpet hemocyanin (KLH), and are then injected as an emulsion with an adjuvant. In animal studies, immunization with kinoids induces high titers of polyclonal neutralizing antibodies against the targeted cytokine[.]

2013 February, Bernard R. Lauwerys, Eric Hachulla, François Spertini et al., “Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α–kinoid”, in Arthritis & Rheumatism, volume 65, number 2, →DOI, page 448:

(immunology) An immunogenic preparation containing a biologically inactivated cytokine, used experimentally as a form of vaccination to induce the production of antibodies against overproduced cytokines in several immune-related conditions (e.g. systemic lupus erythematosus, AIDS and Crohn's disease).


iberdomide

Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).

2022 March 17, Joan T. Merrill, Victoria P. Werth, Richard Furie et al., “Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus”, in The New England Journal of Medicine, volume 386, number 11, →DOI, page 1034:

(pharmacology) A derivative of thalidomide used experimentally for the treatment of multiple myeloma and systemic lupus erythematosus.


AVSD

(medicine) Abbreviation of atrioventricular septal defect.


S/MAR

scaffold/matrix attachment region
w:scaffold/matrix attachment region

(genetics) Initialism of scaffold/matrix attachment region.


sensory deprivation

sensory deprivation (plural sensory deprivations)

(healthcare, psychiatry) A situation in which stimulation of human senses, particularly sight and sound, is at a minimum, often to ease a patient's relaxation, such as in a quiet room.


EHL

EHL (countable and uncountable, plural EHLs)

extensor hallucis longus
extensor hallucis longus#English

(anatomy) Initialism of extensor hallucis longus.


organ of Zuckerkandl

organ of Zuckerkandl (plural organs of Zuckerkandl)

First described by Emil Zuckerkandl, a professor of anatomy at the University of Vienna, in 1901.

(anatomy) A chromaffin body derived from the neural crest located at the bifurcation of the aorta or at the origin of the inferior mesenteric artery. It may be the source of a paraganglioma.


save shot

(medicine, slang) An injection of an anti-overdose medication given to a recreational drug user as an emergency measure in life-threatening circumstances.


ISYN

(medicine) Abbreviation of intrasynovial.


peg-and-socket joint

peg-and-socket joint (plural peg-and-socket joints)


balloon syndrome

(medicine, zoology) Subcutaneous emphysema in hedgehogs.


HHCH

Japanese: HHCH (HHCH) (hexahydrocannabihexol)

(organic chemistry, pharmacology) Initialism of hexahydrocannabihexol.


daycase

(medicine) A patient who is admitted to the hospital for a diagnostic test with the intention of being discharged on the same day.


AAo

Coordinate term: DAo

Alternative form: AA

(anatomy) Abbreviation of ascending aorta.


DAo

Coordinate term: AAo (“ascending aorta”)

Alternative form: DA

descending aorta
descending aorta#English

(anatomy) Abbreviation of descending aorta.


WMS

Wechsler Memory Scale
w:Wechsler Memory Scale

(medicine) Initialism of Wechsler Memory Scale.


EMT-I

emergency medical technician
emergency medical technician

(emergency medicine) An intermediate-level emergency medical technician who has passed national registry examination and worked extensively as an EMT-B, but who is not yet a paramedic (EMT-P) level, though usually training to become one.


dyshemoglobinemia

dyshemoglobinemia (countable and uncountable, plural dyshemoglobinemias)

Pulse oximetry has the advantage of being a noninvasive and cost-effective method of providing continuous measurements of arterial oxygen saturation. […] However, pulse oximetry does not measure arterial carbon dioxide tension or pH; it is not a reliable indicator of hyperoxemia; and it can be unreliable in certain patients, such as those with dyshemoglobinemia or sickle cell anemia.

1999, Terry S. LeGrand, Jay I. Peters, “Pulse oximetry: Advantages and pitfalls”, in Journal of Respiratory Diseases, volume 20, number 3, pages 195-206:

Pulse oximetry is universally used for monitoring respiratory status of patients in the ICU. […] Multiwavelength oximeters may prove to be useful in detecting dyshemoglobinemia.

2015, Amal Jubran, “Pulse oximetry”, in Critical Care, volume 19, number 1, →DOI, →PMID, →PMCID, page 272:

(medicine, uncountable) The state or condition in which hemoglobin amounts and/or function are disturbed in any of various ways, as a clinical feature of any of various diseases.

A possible dyshemoglobinemia should be suspected when discordance exists between pulse oximetry readings and physical examination findings.

2008, Anne Hladik, Kecha Lynshue, “Dyshemoglobinemias and pulse oximetry: a therapeutic challenge”, in Journal of Pediatric Hematology/Oncology, volume 30, number 11, →DOI, →PMID, pages 850-852:

(medicine, metonymically, countable) Any of the various disorders or diseases that comprise this feature.


pseudohypoxemia

Pseudohypoxemia or spurious hypoxemia represents a low oxygen tension or saturation in an arterial blood sample that does not correspond with the actual levels in the body. […] A young patient with leukemia and extreme leukocytosis (hyperleukoctosis) who demonstrated pseudohypoxemia is described herein. Clinical experiments on the arterial blood sample from this patient revealed that the phenomenon of pseudohypoxemia was most likely caused by a rapid in vitro oxygen consumption by the excessively large number of immature leukemic cells.

1998, Valentina Di Boscio, Udaya Prakash, “Pseudohypoxemia caused by hyperleukocytosis”, in Journal of Bronchology, volume 5, number 1, pages 43-46:

Pseudohypoxaemia or spurious hypoxaemia is a recurrent problem faced on arterial blood gas analysis in patients with hyperleucocytosis leading to management dilemmas and unnecessary respiratory interventions. Various methods have been suggested to reduce the magnitude of this problem.

2012, K.N. Prasad, Prabhu Manjunath, L. Priya, and Sanjay Sasikumar, “Overcoming the problem of pseudohypoxemia in myeloproliferative disorders: another trick in the bag”, in Indian Journal of Critical Care Medicine, volume 16, number 4, →DOI, →PMID, →PMCID, pages 210–212:

False readings of low oxygen content are rare but can be expected in specific clinical scenarios such as leukemia patients with marked leukocytosis who can develop "leukocyte larceny," a phenomenon of excess oxygen consumption by leukocytes. […] This case report presents a patient with marked leukocytosis from chronic myelogenous leukemia whose extubation was briefly delayed due to pseudohypoxemia on ABG measurements.

2022, Saeid Mirzai, Mark Andreae, Chethan Puttarajappa, “Pseudohypoxemia from leukocyte larceny in a patient with chronic myelogenous leukemia”, in Cureus, volume 14, number 1, →DOI, →PMID, →PMCID, page e21405:

(medicine) A spurious measurement of oxygen saturation of blood, giving a false appearance of hypoxemia; it can happen via technical problems (such as a malfunctioning pulse oximeter) or even when all technical details are correct but hyperleukocytosis or thrombocytosis is present and the testing method is blood gas analysis.


sickle cell trait

I learned from her that I carried the sickle cell trait, which meant I would never be sick, but my child could be, if my husband also carried the trait.

2005, Sefi Atta, Everything Good Will Come, Arris Books, page 44:

(medicine) A genotype, and the carrier state constituted by it, that is the heterozygous counterpart to sickle-cell disease (which involves a homozygous hit). It is not classified as a disease entity because it usually has little clinical effect (generally asymptomatic).


acroposthion

/ækɹə(ʊ)ˈpɒsθɪən/

From Ancient Greek ἀκροπόσθιον (akropósthion).

der

(anatomy) The tip of the foreskin which extends beyond the glans.


expressed emotion

en-noun

expressed emotion (countable and uncountable, plural expressed emotions)

High expressed emotion (EE) experienced by people with mental illness is a known risk factor of relapse.

2022 July 21, Siu-Man Ng, Siyu Gao, Amenda Man Wang, Christine Cheuk, Melody Hiu-ying Fung, “Survey of High Expressed Emotions Experienced By Community Mental Health Service Users in Hong Kong During the COVID-19 Pandemic”, in Schizophrenia Bulletin Open, volume 3, number 1, Oxford, Oxfordshire: Oxford University Press, →DOI, →ISSN, →OCLC, page 1, column 1:

(uncountable, psychiatry) Negative or hostile attitudes expressed towards a person affected by mental illness by their family.


trocarize

en-verb

trocarize (third-person singular simple present trocarizes, present participle trocarizing, simple past and past participle trocarized)

trocarizes (present singular third-person)
trocarizing (participle present)
trocarized (participle past)
trocarized (past)

(surgery, transitive) To perform trocarisation upon.


chavel-bone

From Middle English chavylbone, chavyl bon (also as Middle English chawylbon, chawlbone, jawe bone > Early Modern English chawe bone, chaw-bone, jaw-bone > English jawbone), equivalent to chavel + bone. Doublet of jawbone.

Cain kills Abel with a 'chavel-bone' (jaw bone), as according to apocryphal legend, and then hides his body under a pile of grass or hay.

1991, Colette Rausch, Leigh A. Payne, Medieval Drama, page 39:

It is the cry of Electra […] of Antigone for the father, for the brother struck down by the chavel-bone of Cain, death's storm-trooper, the man of ten-thousand names and ten-thousand faces […]

1992, Joan DeVee Dixon, George Rochberg: A Bio-bibliographic Guide to His Life and Works, page 325:

"With this chavel-bone I shall slay thee!"

2005, John Passfield, Water Lane: The Pilgrimage of Christopher Marlowe, page 120:


rapid response system

en-noun

rapid response system (plural rapid response systems)

(chiefly medicine) The organisation and implication of a rapid response team in a particular setting.


ProMED-mail

(health) Abbreviation of Program for Monitoring Emerging Diseases (the largest publicly available emerging diseases and outbreak reporting systems in the World)


iptacopan

(organic chemistry, pharmacology) A medication used to treat paroxysmal nocturnal hemoglobinuria.


b.i.d.

en-adv

b.i.d. (comparative more b.i.d., superlative most b.i.d.)

more b.i.d. (comparative)
most b.i.d. (superlative)


t.i.d.

t.i.d. (comparative more t.i.d., superlative most t.i.d.)

more t.i.d. (comparative)
most t.i.d. (superlative)

(medicine, pharmacology) Three times a day


physioxia

(physiology) The physiological level of oxygen in a tissue, typically much lower than atmospheric oxygen content due to dissolution in the blood and use by tissues.


polypharyngeal

(anatomy) Having or involving more than one pharynx.


long vax

(medicine, pathology) The manifestation of long-term symptoms as a result of a COVID-19 vaccination.


EGPA

w:eosinophilic granulomatosis with polyangiitis

(pathology) Initialism of eosinophilic granulomatosis with polyangiitis.


brachiocephalic vein

en-noun

brachiocephalic vein (plural brachiocephalic veins)

internal jugular vein
internal jugular vein

(anatomy) Either of the two large veins that are formed by the confluence of the internal jugular vein and subclavian vein in the root of the neck, and unite to form the superior vena cava.


primaxial

primaxial muscle

(anatomy) comprised of somitic cells only


female pattern baldness

Coordinate term: male pattern baldness

(dermatology) A pattern of hair loss (alopecia) in women caused by hormones, aging and genetics, manifesting as overall thinning but which maintains the normal hairline.


ophthalmodynia periodica

(medicine) A primary headache disorder which causes stabbing sensations, usually in one area of the head.


suction tip

But, once the fluid has been drained off, the suction tip has now been firmly clamped to the child’s body, and the child is being pulled in a downward direction, by the abortionist’s suction tip with the negative pressure applied to it, and the body is now being torn, systematically, from the head.

1984, Bernard Nathanson, The Silent Scream:

Of course, one must take care not to inadvertently seal the ear canal with the suction tip, thereby risking "tympanic membrane barotrauma" and possibly sucking out the patient's brains.

1997 September 19, Cecil Adams, “the Straight Dope”, in Chicago Reader:

(medicine) A Yankauer suction tip, a medical suctioning instrument.


thoraco-omphalopagus

(medicine, of conjoined twins) Joined at the thorax and the navel.


sore eyes

(Philippines, pathology) conjunctivitis; pinkeye


CAKUT

CAKUT (countable and uncountable, plural CAKUTs)

(medicine) Initialism of congenital anomaly of the kidney and urinary tract.


sound therapy

Demonstrated by experienced professionals, the fair will provide the opportunity to learn about unique healing methods such as Chakra Healing, Sound Therapy, Reiki, Kinesiology and Crystal Healing.

2023 December 21, The Central Coast Community News, NSW, page 16, column 2:

alternative medicine
alternative medicine

(alternative medicine) The practice of using the supposed therapeutic effects of sounds to cure illness.


chakra healing

(alternative medicine) The practice of using the supposed therapeutic effects of chakras to balance and harmonize energy centers in the body and hence cure illness.


cephalothoracoomphalopagus

(medicine, of conjoined twins) Joined at the head, thorax, and abdomen.


language delay

(medicine, psychology, linguistics) A condition where a child does not acquire language skills within the typical age range.


enzybiotic

(pharmacology) An experimental enzyme used in antibacterial therapy.


goofy juice

LL-Q1860 (eng)-Flame, not lame-goofy juice.wav

(psychiatry, humorous) A liquid medication once used to tranquilize psychiatric patients.


pulseless electrical activity

pulseless electrical activity (uncountable)

(pathology) A medical condition in which the heart's electrical activity is present on an electrocardiogram but doesn't result in a pulse.


symmetrical OCD

obsessive-compulsive disorder
obsessive-compulsive disorder

(medicine, psychology) A form of obsessive-compulsive disorder (OCD) in which the sufferer's compulsions are demonstrated by an irrational desire for symmetry in their life.


zombie system

If, however, you happen to be an organism with plenty of input sensors and output effectors, say, a mammal, devoting a zombie system to each and every possible input-output combination became too expensive .

2004, Christof Koch, The Quest for Consciousness: A Neurobiological Approach, page 318:

Second , it seems that information can flow from the phenomenal level to the non-conscious zombie systems, but not the other way round (Bridgeman, 2000). In some cases of visually guided actions, when a delayed response to the stimulus is required, the nonconscious system cannot store the relevant representations, but must rely on those delivered by the conscious system. This also shows clearly that the nonconscious system is a servant of the consciously selected goals . Interestingly , the information available through the phenomenal level is not as accurate for the purposes of motor programming as the normal direct online input of this zombie system is, for the representations filtered through the phenomenal level include distortions and illusions that the nonconscious system is not otherwise inclined to generate.

2006, Antti Revonsuo, Inner Presence: Consciousness as a Biological Phenomenon, page 378:

The hard problem holds that if a certain activity is found in the mechanics which seems to influence consciousness, it is logically possible for exactly the same activity to occur without there being consciousness at all. This would be called a Zombie system .

2008, D. Dubois, Computing Anticipatory Systems, page 4:

The study of zombie systems may give us reason to reconfigure our intuitive conception of the relationship between consciousness and agency ( see e.g. Clark 2001 ) , but by no means does it show that 'in order to discover what someone is conscious of we need them to give us some form of report about their subjective experience' (Frith et al. 1999:107).

2012, Tim Bayne, The Unity of Consciousness:

(neurobiology) A neurological system that functions without conscious direction.


liver rot

(pathology) infestation with liver flukes, fascioliasis


SCD

sudden cardiac death
sudden cardiac death#English

(pathology) Abbreviation of sudden cardiac death.


tyriasis

(medicine, archaic) The falling out of the hair.


metaplastic carcinoma

metaplastic carcinoma (countable and uncountable, plural metaplastic carcinomas)

(medicine, oncology) A heterogeneous group of cancers that exhibit varied patterns of metaplasia and differentiation along multiple cell lines.


oat cell

small-cell carcinoma
small-cell carcinoma

(medicine, pathology) A small oval cell that resembles an oat grain and is characteristic of small-cell carcinoma.


small-cell carcinoma

small-cell carcinoma (plural small-cell carcinomas)

(medicine, oncology) A type of highly malignant cancer that most commonly arises within the lung.


schiz

en-adj

schiz (comparative more schiz, superlative most schiz)

more schiz (comparative)
most schiz (superlative)

Clipping of schizophrenic. Compare schizo, schizoid.

a schiz patient

Taggart, and Chusid are goin' up to the schiz ward. Grein is being released on her own, pending she stays on her meds.

1997, Matthew Hall, The Art of Breaking Glass, Boston, M.A. […]: Little, Brown and Company, →ISBN, page 18:

"Kolla," Simon said. "She's really good. She counsels for us. You're having a little schiz break," he said.

1998, Steven Barnes, Iron Shadows, New York, N.Y.: Tor Books, →ISBN, page 207:

Go into the doctor's office. He gives you schiz meds, you take them and the doctor and his office disappear.

2020 October 10, u/Tactical_Salt, “That's a big big win”, in Reddit, r/dankmemes, archived from the original on 2024-01-20:

(psychiatry, slang) Involving or pertaining to schizophrenia (in the medical sense); schizophrenic.


bowel transit time

(medicine, gastroenterology) The amount of time that it takes for food to travel from the mouth to the end of the intestine.


nonacrocentric

nonacrocentric (comparative more nonacrocentric, superlative most nonacrocentric)

more nonacrocentric (comparative)
most nonacrocentric (superlative)

The derivative that is lacking is formed by the complete acrocentric short arm and the proximal long arm segment and perhaps a terminal segment from the nonacrocentric chromosome.

1988, Art Daniel, The Cytogenetics of Mammalian Autosomal Rearrangements, page 56:

In other words, acrocentric-derived sSMC tend to be transmitted more easily from one generation to the next than nonacrocentric ones; the first can apparently survive male and female meiosis more easily, whereas nonacrocentric ones seem to face more problems there.

2011, Thomas Liehr, Small Supernumerary Marker Chromosomes (sSMC), page 17:

Gabriel-Robez et al. have shown a ratio of 1:4 for translocations with an acrocentric present, compared with nonacrocentric translocations in fertile males.

2020, Christopher Bob Gillies, Fertility and Chromosome Pairing, page 22:

(genetics, of a chromosome) Having the centromere near the middle, and thus having roughly equal-sized arms.


PKS

polycystic kidney syndrome
polycystic kidney syndrome#English

(pathology) Initialism of polycystic kidney syndrome.


FVRCP

(veterinary medicine) Initialism of feline viral rhinotracheitis, calicivirus, and panleukopenia (“a vaccine for cats against these three diseases”).


South Beach Diet

en-noun

South Beach Diet (plural South Beach Diets)

(medicine, nutrition) A fad diet developed by Arthur Agatston emphasizing eating food with a low glycemic index.


NAcc

nucleus accumbens
nucleus accumbens#English

(neuroanatomy) Acronym of nucleus accumbens.


reward system

(neuroanatomy) A group of neural structures responsible for incentive salience, associative learning, and positively-valenced emotions, particularly ones involving pleasure as a core component (e.g., joy, euphoria and ecstasy).


HIPP

(neuroanatomy) Abbreviation of hippocampus.


mesolimbic pathway

mesolimbic pathway (plural mesolimbic pathways)

ventral tegmental area
ventral tegmental area

(neuroanatomy) A collection of dopaminergic neurons that project from the ventral tegmental area (VTA) to the ventral striatum.


Z chromosome

Coordinate term: W chromosome

(genetics) The larger chromosome that has more genes, in the ZW system.


W chromosome

Coordinate term: Z chromosome

(genetics) The smaller chromosome that has fewer genes, in the ZW system.


HeLa cell

Named after the American cancer patient Henrietta Lacks.

named-after

(medicine, cytology) An immortal cell line that can divide an unlimited number of times in a laboratory cell culture plate, as long as fundamental cell survival conditions are met.


hypertherm

(medicine, historical) A heated enclosure used to provoke fever in a patient.


chair time

en-noun

chair time (countable and uncountable, plural chair times)

(medicine) The amount of time in which a patient spends in the chair of a doctor or other medical professional.


vaccine injury

vaccine injury (plural vaccine injuries)

(medicine, pathology) An adverse event that occurs following vaccination.


sojourn time

sojourn time (countable and uncountable, plural sojourn times)

(medicine, pathology) A preclinical detectable period in the screening of a disease.


alarm reaction

(medicine, physiology) The initial symptoms which the body or another organism experiences when undergoing stress.


median lethal time

median lethal time (usually uncountable, plural median lethal times)

(toxicology) The average time interval during which 50% of a given population may be expected to die following the administration of a chemical or physical agent at a given concentration.


left ventricular ejection time

left ventricular ejection time (countable and uncountable, plural left ventricular ejection times)

left ventricular ejection times (plural)

(medicine, cardiology) The time interval from the moment of the opening of the aortic valve to the moment of its closure.


prothrombin time

prothrombin time (countable and uncountable, plural prothrombin times)

(medicine, hematology) The amount of time required for the plasma of one's blood to clot.


digital pad

From digital (“relating to fingers or toes”) + pad (“cushion-like thickening of the skin on the underside of the toes of animals”).

com

(anatomy) A load-bearing pad on the underside of a toe of an animal's paw.


pill bottle

(British, medicine) a small bottle that pills are kept in


ecarin clotting time

(medicine, hematology) A laboratory test used to monitor anticoagulation during treatment with hirudin.


SPINA-DI

Abbreviation of structure parameter inference approach-disposition index.

abbreviation of

(endocrinology) The loop gain of insulin-glucose homeostasis, calculated from the product of secretory capacity of pancreatic beta cells (SPINA-GBeta) times insulin receptor gain (SPINA-GR).


association time

en-noun

association time (countable and uncountable, plural association times)

(medicine, psychology) The amount of time elapsing between the moment of a stimulus and the moment of its verbalized response.


blood circulation time

blood circulation time (countable and uncountable, plural blood circulation times)

(medicine, hematology) The amount of time taken by a blood particle to travel from one point in the circulation to the other; the average linear velocity of blood.


antirepair

an antirepair pathway

an antirepair effect

The increased levels of mature miRNAs could play a role in the DNA damage response by (1) decreasing the levels of antirepair genes (such as the antirecombinases, Srs2, PARI, RTEL1 [122]) (2) downregulating DDR proteins through a feedback regulation loop to restore pre-DNA damage levels.

2017, Alexey Moskalev, Alexander Vaiserman, Epigenetics of Aging and Longevity, page 174:

(genetics) Inhibiting the repair of damaged DNA.


tela choroidea

(anatomy) A region of meningeal pia mater that adheres to the underlying ependyma, and gives rise to the choroid plexus in each of the brain's four ventricles.


prostaticovesical

(anatomy) Relating to the prostate and the urinary bladder.


circulation time

circulation time (countable and uncountable, plural circulation times)

Table II shows the results of measurements of the diastolic volume of the heart, the stroke output of the heart, the mechanical work of the heart, the circulation time and calculated increase in mechanical efficiency of the heart as well as the venous pressure in the systemic circulation in cases of heart failure.

1949, Cecil James Watson, Outlines of Internal Medicine - Volumes 1-5, page 256:

No correlation has been found between blood pressure and circulation time in either healthy or diseased individuals (Blumgart & Weiss 1927, Olsone 1941, Kerpel-Fronius 1950).

1953, Leena Tuuteri, On the Circulation Time and the Oxygen Saturation of Sinus Blood in Severe Infantile Gastroenteritis, page 24:

The time measured by us can, thus, be regarded as the true "lymph circulation time".

2013, István Rusznyák, Mihály Földi, György Szabó, Lymphatics and Lymph Circulation, page 271:

In 1897 George Neil Stewart, formerly a student of the English physiologist William Stirling, and later professor of physiology at Western Reserve University, published a series of experiments on the circulation time.

2013, Alfred P. Fishman, Dickinson W. Richards, Circulation of the Blood: Men and Ideas, page 105:

(medicine) The time it takes for a fluid to complete its circuit of the body, especially the time it takes blood to circulate.


MGB

medial geniculate body
medial geniculate body#English

(anatomy) Initialism of medial geniculate body.


time agnosia

(medicine, psychology) The inability to sense the elapsing or passing of time.


PCNA

proliferating cell nuclear antigen
w:proliferating cell nuclear antigen

(genetics) Initialism of proliferating cell nuclear antigen.


electrovestibulography

(medicine) A non-invasive, neuroelectrophysiological medical technique that measures vestibuloacoustic neural activities for the diagnosis of various neurodegenerative and neuropsychiatric disorders.


EVestG

(medicine) Abbreviation of electrovestibulography.


spoon of Diocles

spoon of Diocles (plural spoons of Diocles)

(historical, surgery) An ancient Roman surgical instrument said to have been designed by Diocles of Carystus to remove arrows from the human body.


activated clotting time

activated clotting time (countable and uncountable, plural activated clotting times)

(medicine, hematology) A test of coagulation, used to monitor anticoagulation effects.


partial thromboplastin time

partial thromboplastin time (countable and uncountable, plural partial thromboplastin times)

(medicine, hematology) A blood test that characterizes coagulation of the blood.


isovolumic relaxation time

isovolumic relaxation time (countable and uncountable, plural isovolumic relaxation times)

(medicine, cardiology) An interval in the cardiac cycle, from the aortic component of the second heart sound, to the onset of filling by opening of the mitral valve.


time of useful consciousness

(aviation, pulmonology) The amount of time a person is able to function effectively in an environment of inadequate oxygen supply.


thoraco-omphalo-ischiopagus

(medicine, of conjoined twins) Joined at the thorax, the navel and the pelvis.


xipho-omphalopagus

(medicine, of conjoined twins) Joined at the xiphoid process and the navel.


xiphoomphaloischiopagus

(medicine, of conjoined twins) Joined at the xiphoid process, the navel and the pelvis.


ischiocrural

/ˌɪskiəʊˈkɹʊəɹəl/

From ischium + crus + -al, an occasional coinage gradually gaining ground over the 20th century.

The ischiocrural muscle complex is the most frequently injured musculotendineous structure in athletes. Indirect trauma, typically during sprints or jumps, is the most common mechanism leading to muscle strains of this anatomical structure. However, proximal ruptures of the entire ischiocrural tendon complex at the ischial tuberosity represent a rare injury and reports in the literature are limited.

2004 December 16, Peter U. Brucker, Andreas B. Imhoff, “Functional assessment after acute and chronic complete ruptures of the proximal hamstring tendons”, in Knee Surgery, Sports Traumatology, Arthroscopy, volume 13, →DOI, pages 411–418:

(anatomy) Located between the ischium and the crures.


recalcification time

recalcification time (countable and uncountable, plural recalcification times)

(medicine, hematology) A measure of the amount of time required for the formation of a clot in recalcified blood.


bronchi-

(anatomy) (combining form) relating to bronchi


time-marker

(physiology, psychology) An instrument that traces the timeline, usually in seconds, upon the smoked paper of a kymograph in physiologic experiments.


antiemphysemic

en-adj

antiemphysemic (comparative more antiemphysemic, superlative most antiemphysemic)

more antiemphysemic (comparative)
most antiemphysemic (superlative)

By surface analysis, anti- + emphysema + -ic

surf

(medicine, uncommon) Against emphysema; counteracting emphysema.


-osmia

From Ancient Greek ὀσμή (osmḗ, “smell, scent, odour”).


Mitrofanoff procedure

en-noun

Mitrofanoff procedure (plural Mitrofanoff procedures)

(medicine) A surgical procedure in which the appendix is exsected and connected between the bladder and navel.


SUNDS

Coordinate term: Brugada syndrome

sudden unexplained nocturnal death syndrome#English

(pathology) Acronym of sudden unexplained nocturnal death syndrome.


abortion doctor

abortion doctor (plural abortion doctors)

(medicine, often derogatory) A surgeon who performs an abortion.


Placidyl

Placidyl (countable and uncountable, plural Placidyls)

Marketing name, apparently from placid + -yl.

His horror of insomnia, compounded with a family history of compulsive worrying, caused him to down three or four Placidyls, Seconals, Quaaludes, or Tuinals almost every night—and often it was a combination of all four.

1985, Priscilla Presley, Sandra Harmon, Elvis and Me, Putnam, →ISBN, page 151:

(pharmacology) Trade name of ethchlorvynol, a sedative.


parent drug

(pharmacology) The initial compound in a biotransformation reaction, requiring metabolism for activation.


sudden unexplained nocturnal death syndrome (uncountable)

(pathology) A condition that predominantly strikes young healthy males from Southeast Asia, causing unexplained death while sleeping.


tearout

tearout (countable and uncountable, plural tearouts)

When testing the suture tearout force, Tauber and Seidel found that the tearout force was one third to one fourth of normal tissue.

2012, Volker Schumpelick, Andrew N Kingsnorth, Incisional Hernia:

The resistance of screws to tearout forces depends chiefly on the screw diameter ( and bone strength ) and on the length of screw thread gripping the bone (cortical thickness).

2012, Urs Heim, Karl M. Pfeiffer, Internal Fixation of Small Fractures, page 34:

Backward traction on the capsular flap forms the basis of a predictable technique for rescuing the capsulorrhexis from a radial tearout.

2022, Myron Yanoff, Jay S. Duker, Ophthalmology, page 354:

(medicine) The tearing of tissue at the position of an incision, suture, staple, pin, etc.


Evzio

(pharmacology) An opioid antagonist indicated for the emergency treatment of a known or suspected opioid overdose.


Nyxoid

(pharmacology) A single-dose nasal spray used for the emergency treatment of an opioid overdose.


adverse event

adverse events in the treatment group

adverse events in the control group

en:any happening that is bad, regardless of causality

(medicine, pathology) Any occurrence that has any negative (deleterious) influence (in any degree from mild to severe).


valve of Kerckring

valve of Kerckring (plural valves of Kerckring)

(anatomy) Any of the large valvular flaps projecting into the lumen of the small intestine.


Chinese hamster ovary cell

Chinese hamster ovary cell (plural Chinese hamster ovary cells)

(biology, zoology, cytology) A family of immortalized cell lines derived from the epithelial cells of the ovary of the Chinese hamster, often used in biological and medical research and commercially in the production of recombinant therapeutic proteins.


immunity gap

The entry of E. coli in a protein-rich medium into the small intestine, which has a damaged surface from the switch to solid feed, at a time when the pig's immune response is normally low (the immunity gap), presents a high risk for a secretory diarrhea.

2007, Neville G. Gregory, Temple Grandin, Animal Welfare and Meat Production, page 104:

The actual age at which the immunity gap develops depends on the amount of maternally derived antibody (MDA) transferred to each kitten.

2008, E. A. Chandler, R. M. Gaskell, C. J. Gaskell, Feline Medicine and Therapeutics, page 15:

Prior to this, young animals face an 'immunity gap': passive immunity is reduced and the animal's own immune system is not yet fully capable of combating pathogens.

2021, Food and Agriculture Organization of the United Nations, Animal nutrition strategies and options to reduce the use of antimicrobials in animal production, page 11:

(veterinary medicine) The time period during which a young mammal no longer receives effective immunity to diseases from antibodies in its mother's milk but its own immune system is not fully developed.

However, an immunity gap in adults coupled with the presence of large numbers of susceptible children and adolescents creates the potential for an extensive epidemic.

2009, Michael R. Dobbs, Clinical Neurotoxicology, page 437:

Thus with the usual booster (third dose) at 5-6 months there is only a small risk of an immunity gap.

2016, David E. Swayne, Animal Influenza, page 530:

While prior studies in Pakistan indicated near universal exposure to hepatitis A by age 14 years, the incidence of acute hepatitis A among adults has increased in recent years, indicating an immunity gap.

2022, Walter A. Orenstein, Paul A. Offit, Kathryn M. Edwards, Plotkin's Vaccines, page 902:

(epidemiology) The time period between when an individual's or a population's immunity to a virus has waned (due to normal decrease in immune response over time or to the development of a new strain of the virus) and before a new vaccine can be given to boost immunity.


hypervaccination

“The observation that no noticeable side effects were triggered in spite of this extraordinary hypervaccination indicates that the drugs have a good degree of tolerability,” Schober said.

2024 June 3, Kate Connolly, “‘Hypervaccinated’ man reportedly received 217 Covid jabs without side effects”, in The Guardian:

(medicine, immunology) An excessive administration of a vaccine.


DoxyPEP

(medicine) post-exposure preventative treatment which reduces the chance of getting bacterial STIs (such as syphilis, chlamydia, and gonorrhea)


Nuss procedure

(surgery) A minimally invasive procedure for treating pectus excavatum, involving the insertion of one or more bars under the sternum through small incisions in the side of the chest, using a thoracoscope for guidance.


hot piping

(slang, drugs) A form of smoking of illegal narcotics using tinfoil, a lighter and a straw to ingest the drugs.


stylocone

(dentistry) A pyramidal lobe on a molar with a spiky projection.


AFBN

(medicine) Initialism of acute focal bacterial nephritis.


acinal

(anatomy) Of, pertaining to, or located in an acinus.


corneal dystrophy

corneal dystrophy (countable and uncountable, plural corneal dystrophies)

(pathology) A group of genetic diseases which cause overgrowth and malformation of the cornea.

congenital hereditary endothelial dystrophy

Meesmann juvenile epithelial corneal dystrophy

posterior polymorphous corneal dystrophy

subepithelial mucinous corneal dystrophy


dope stick

He hands the dope-stick to his partner who drives with one hand on the steering-wheel and the other toking on the blunt.

2010, Reverend James R. Harris, Jesus in Columbus, page 6:

She shrugged and set down the dope stick she'd been puffing on.

2012, Alan Dean Foster, The Moment of the Magician:

Before he could finish his dope stick, a dope fiend came up asking for a twenty rock of crack.

2014, Mr. Mafia, The Last Birdman, page 40:

(slang, drugs) A marijuana joint or cigar laced with cocaine.


health maintenance organization

health maintenance organization (plural health maintenance organizations)

health maintenance organizations (plural)

(US, medicine) A medical insurance group that provides health services for a fixed annual fee.


herpes simplex virus

herpes simplex virus (countable and uncountable, plural herpes simplex viruses)

(medicine, virology) One of two members of the human Herpesviridae family, a set of viruses that produces viral infections in the majority of humans.


necrosmia

(medicine) A form of cacosmia in which the odor of death is imagined.


RNA interference

(genetics) A biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression.


nil per os

From Latin nil (“nothing”) + per (“by means of”) + os (“mouth”), literally “nothing by mouth”.

The initial written orders should include: insulin dosage to be administered as soon as the patient appears nil per os, measure all intake and output, and obtain venous blood for measurement of blood or serum urea nitrogen, glucose, acetone [...] and phosphorus.

1971, Diabetes Mellitus: Diagnosis and Treatment, volume 3, American Diabetes Association, page 252:

We evaluated the effect of Colestid on enteral feeding-induced diarrhea in a double-blind placebo-controlled study. Nineteen patients who were nil per os (NPO) for 5 days before initiation of enteral feeding were enrolled in the study and treatment continued for 7 days.

1998 June 7, DeMeo, M et al., “Beneficial effect of a bile acid resin binder on enteral feeding induced diarrhea.”, in The American Journal of Gastroenterology, volume 93, number 6, Elsevier, Abstract:

Table 34.3: Nil per os odds ratio

2021 April 7, Couloures, K. G. and Hertzog, J. H., “Adverse Events: Risk Factors, Predictors, and Outcomes”, in Mason, Keira P., editor, Pediatric Sedation Outside of the Operating Room: A Multispecialty International Collaboration, Springer International Publishing, →ISBN, page 669:

(medicine) Nothing may be eaten or drunk.


NBM

(medicine) Initialism of nil by mouth (“nothing may be eaten or drunk”).


epididymodeferential

(anatomy) Relating to the epididymis and the vas deferens.


medical cannabis

medical practitioner
medical practitioner

(medicine) Cannabis and cannabinoids that are prescribed by a medical practitioner for their patients.


α-Methylfentanyl

(pharmacology, drugs) An opioid analgesic that is an analog of fentanyl.


anteapical

en-adj

anteapical (comparative more anteapical, superlative most anteapical)

more anteapical (comparative)
most anteapical (superlative)

Legs flavescent, femora with coarse, coalescing round, castaneous spots, some forming anteapical annulus, tibiae with vague, irregularly scattered castaneous dashes; tarsi light castaneous.

1965 September, Herbert Ruckes, “Several New Genera and Species of Discocephaline Pentatomids (Heteroptera: Pentatomidae)”, in Journal of the New York Entomological Society, volume LXXIII, number 3, New York, N.Y.: New York Entomological Society, →ISSN, →JSTOR, →OCLC, page 127:


serratiform

serratiform (comparative more serratiform, superlative most serratiform)

more serratiform (comparative)
most serratiform (superlative)

Incomplete capsular encroachment includes areas of irregular, serratiform and/or undulating inner capsular contour, perpendicular dentate capsular incursions and horizontally disposed (entrapped) intracapsular follicles, which do not qualify, though they should prompt further detailed scrutiny, as should any unexplained area of capsular expansion.

2018, John C Watkinson, Raymond W Clarke, editors, Scott-Brown's Otorhinolaryngology: Head and Neck Surgery, eighth edition, volume 1, Boca Raton, F.L. […]: CRC Press, →ISBN, page 668:


turbinately

en-adv

turbinately (comparative more turbinately, superlative most turbinately)

more turbinately (comparative)
most turbinately (superlative)

(anatomy) Of, or relating to, the turbinate bone.


sensation time

en-noun

sensation time (countable and uncountable, plural sensation times)

(medicine, ophthalmology) The minimal amount of time in which a visual image must be exposed in order to be perceived.


turbo cancer

turbo cancer (countable and uncountable, plural turbo cancers)

(medicine, oncology) A type of fast-developing cancer purported to occur in people who have been vaccinated against COVID-19, especially with mRNA vaccines.


vadadustat

(organic chemistry, pharmacology) A drug used to treat symptomatic anemia associated with chronic kidney disease.


IPD

IPD (countable and uncountable, plural IPDs)

Parkinson's disease
Parkinson's disease#English

(medicine) Initialism of idiopathic Parkinson's disease.

impulsive personality disorder
impulsive personality disorder#English

(medicine) Initialism of impulsive personality disorder.

(medicine) Initialism of inpatient department.

(medicine) Initialism of invasive pneumococcal disease.

(anatomy) Initialism of interpupillary distance.


urotoxia

(medicine, obsolete) The poisonous content of the urine.


ERPC

(medicine) Initialism of evacuation of retained products of conception.


penile cancer

penile cancer (countable and uncountable, plural penile cancers)

(oncology) Cancer of the skin or tissues of the penis.


NRH

(medicine) Initialism of nodular regenerative hyperplasia.


oral surgeon

(medicine, surgery) A specialist in oral surgery.


oral surgery

(medicine, surgery) Any type of surgical procedure performed on the teeth, gums, jaws or other oral structures.


LASA

(pharmacology) Initialism of look alike sound alike. (referring to pharmaceuticals that are visually similar in physical appearance or packaging and similar in their names, orthographies, or phonetics).


fading time

fading time (countable and uncountable, plural fading times)

(medicine, ophthalmology) The amount of time required for a constant stimulus that is applied to a fixed area of the peripheral visual field to dissipate.


isoxepac

non-steroidal anti-inflammatory drug
non-steroidal anti-inflammatory drug

(pharmacology) A non-steroidal anti-inflammatory drug with analgesic activity. It is also used as an intermediate in the synthesis of olopatadine hydrochloride.


amenamevir

Amenamevir … exerts antiviral action by inhibiting the enzymatic activity of a virus-derived helicase.

2019, Maeda H, Nakamura H, Kikukawa Y. Pharmacological profiles and clinical effects of amenamevir tablet as treatments for herpes zoster. Nihon Yakurigaku zasshi. Folia Pharmacologica Japonica. Volume 153(1). PMID: 30643090. pages 35-43

(pharmacology) An oxadiazole phenyl derivative, an antiherpes agent that does not have a nucleic acid-like structure.


schizophrenia spectrum

schizotypal personality disorder
schizotypal personality disorder

schizoid personality disorders
schizoid personality disorders

(psychiatry) A classification of psychiatric disorders related to schizophrenia, also including schizotypal personality disorder, schizoid personality disorders and others.


ipseity disturbance

schizophrenia spectrum
schizophrenia spectrum

(psychiatry) A symptom of schizophrenia spectrum disorders characterized by disturbances in the patient's sense of self.


duoperone

(pharmacology) A phenothiazine, C₂₈H₂₆F₄N₂OS with neuroleptic and antiemetic properties. It has a prolonged duration of action.


chloroplast DNA

chloroplast DNA (plural chloroplast DNAs)

(cytology, molecular biology) DNA that is located in chloroplasts.


eccDNA

(cytology, molecular biology) A type of double-stranded circular DNA structure found in the eukaryotic nuclei of plant and animal (including human) cells.


ecDNA

(cytology, molecular biology) Any DNA that is found off the chromosomes, either inside or outside the nucleus of a cell.


C-DNA

(cytology, molecular biology) One of the many possible double helical conformations of DNA, induced to take this form in particular conditions such as relatively low humidity and the presence of certain ions.


microDNA

(cytology, molecular biology) The most abundant subtype of extrachromosomal circular DNA eccDNA in humans, typically ranging from 200-400 base pairs in length and enriched in non-repetitive genomic sequences with a high density of exons.


organellar DNA

(cytology, molecular biology) DNA contained in organelles, such as mitochondria and chloroplasts, outside the nucleus of eukaryotic cells.


siDNA

(cytology, molecular biology) A class of short modified double-stranded DNA molecules, 8–64 base pairs in length.


Hoogsteen base pair

Hoogsteen base pair (plural Hoogsteen base pairs)

(cytology, molecular biology) A variation of basepairing in nucleic acids such as the A•T pair.


dosmalfate

Dosmalfate … has been developed and marketed in some countries for therapeutic use in the healing of gastric and duodenal ulcers.

2003, Isabel Villegas, Carmen La Casa, Aurelio Orjales, Catalina Alarcón de la Lastra. Effects of dosmalfate, a new cytoprotective agent, on acute and chronic trinitrobenzene sulphonic acid-induced colitis in rats. European Journal of Pharmacology. Volume 460(2-3). page 210

(pharmacology) A diosmin heptakis (hydrogen sulfate) aluminium complex, a non-systemic cytoprotective drug.


self-disorder

ipseity disturbance
ipseity disturbance#English

(psychiatry) Synonym of ipseity disturbance


underadherence

LL-Q1860 (eng)-Flame, not lame-underadherence.wav

Because of the substantial personal, social, and economic consequences of patients’ underadherence to medication regimens, the prevalence and impact of underadherence to antipsychotic regimens have been studied extensively.

2007 June, Min Yang, Jamie C. Barner, Jason Worchel, “Factors Related to Antipsychotic Oversupply Among Central Texas Veterans”, in Clinical Therapeutics, volume 29, number 6, →DOI, page 1214:

(medicine) Insufficient adherence to a treatment.


underadherent

en-adj

underadherent (comparative more underadherent, superlative most underadherent)

more underadherent (comparative)
most underadherent (superlative)

LL-Q1860 (eng)-Flame, not lame-underadherent.wav

Although half of adult outpatients receiving antipsychotic monotherapy in the CTVHCS were adherent to their treatment regimens, a large proportion were underadherent, and a small proportion had medication oversupply.

(medicine, of a person) Showing underadherence to a treatment; insufficiently adherent.


FGA

Coordinate term: SGA

first-generation antipsychotic
w:typical antipsychotic

(pharmacology) Initialism of first-generation antipsychotic.


ReA

reactive arthritis
reactive arthritis#English

(pathology) Abbreviation of reactive arthritis.


not for

He is not for resuscitation.

After discussion with her family, she was deemed not for ICU admission.

(medicine, UK, Australia, New Zealand) Not to be subjected to (a procedure); indicates that the patient, or relevant carers or next of kin, have specifically requested that the procedure not be carried out.


clearance time

en-noun

clearance time (countable and uncountable, plural clearance times)

It should be emphasized, however, that if the drug detection methods are only marginal, the effects of increased doses on clearance time can be quite marked (Fig 4).

1982, R. A. Mansmann, E. S. McAllister, Paul W. Pratt, Equine Medicine and Surgery, page 162:

The results revealed that sleep infusions in both groups were associated with a statistically significant prolongation of acid clearance time. In minutes, the absolute clearance time was nearly doubled in both groups.

2017, S.R. Pandi-Perumal, Meera Narasimhan, Milton Kramer, Sleep and Psychosomatic Medicine, page 17:

Another factor of interest for dental caries is the individual oral clearance time, i.e., the time it takes for a person to eliminate the food from the mouth without respect to various properties of the food itself.

2019, Lars Granath, William D. McHugh, Systemized Prevention of Oral Disease: Theory and Practice:

The amount of time it takes to empty something out.

(medicine, pathology) The amount of time for a substance to be eliminated from a body, body part or organ.


time-gain compensation

(medicine) A setting applied in diagnostic ultrasound imaging to account for tissue attenuation, in which the received signal intensity with depth is increased.


crowned dens syndrome

Named by Jean-Pierre Bouvet et al. in December 1985 in Arthritis and Rheumatism.

[see title]

1985 December, Jean-Pierre Bouvet, Jean-Marie le Parc, Bernard Michalski, Charif Benlahrache, Louis Auquier, “Acute neck pain due to calcifications surrounding the odontoid process: The crowned dens syndrome”, in Arthritis and Rheumatism, volume 28, number 12, →DOI, page 1417:

calcium pyrophosphate
calcium pyrophosphate

(medicine) A clinical and radiological syndrome caused by the deposition of calcium pyrophosphate crystals in the ligaments surrounding the odontoid process, characterized by acute occipital pain, limited neck mobility and typical radiographic findings.


infraoccipital

Tomography revealed a disappearance of the infraoccipital calcium deposits (Figure 1B), which was confirmed by computed tomography.


high-T

(slang, medicine, andrology) High levels of testosterone in a body.


SIRT

SIRT (countable and uncountable, plural SIRTs)

(medicine) Initialism of selective internal radiation therapy


doll's eye sign

From the inability of traditional dolls' eyes to mimic babies' responses to being carried around.

(medicine) Negative oculocephalic reflex, sometimes indicating brain stem dysfunction.


cyclohexyloxycarbonyloxyethyl

/ˌsaɪkləʊˌhɛksɪlˌɒksɪkˌɑːbənɪlˌɒksiˈɛθɪl/

/ˌsaɪkləʊˌhɛksɪlˌɒksiˌkɑːbənɪlˌɒksiˈɛθɪl/

From cyclohexyl + oxy + carbonyl + oxy + ethyl.

compound

(pharmacology) The ester in which prodrug form candesartan is prepared for administration in order to increase its bioavailability.


biobetter

From bio- + better. Coined by Indian business executive G. V. Prasad, managing director of Dr. Reddy's Laboratories, in 2007.

coinage

Coordinate term: biosimilar

In general, originators have short-term options available, such as patent litigation, but should focus on sustainable long-term strategies such as development of biobetters or incorporating biosimilars as complements to existing products.

2016 February, Daniel Casey, “Key strategic factors for stakeholders in the current global biosimilar market”, in Drug Discovery Today, volume 21, number 2, →DOI, page 208:

(pharmacology) A medication developed by modifying an approved biological drug to enhance its properties (e.g., improved efficacy, higher selectivity or lower toxicity).


i.v.

Alternative form: IV


s.c.

Alternative form: SC

(medicine) Abbreviation of subcutaneous.


i.p.

Alternative form: IP

(medicine) Abbreviation of intraperitoneal.


M.R.C.Psych.

w:Member of the Royal College of Psychiatrists

(UK, psychiatry, postnominal qualification) Initialism of Member of the Royal College of Psychiatrists.


off the shits

(slang, drugs) Extremely high; tripping, wired, etc..


triple-stranded

(genetics) That have three helical strands of nucleic acid that wind around each other and are connected by hydrogen bonds.


orthomitosis

The first is that division at any phase of the life eyele should be by this or that method (e.g., orthomitosis) and according to methods which have been studied in detail in the Metazoa.

1968, David Weinman, Miodrag Ristic, editors, Infectious Blood Diseases of Man and Animals, page 369:

Golgi bodies and mitochondria with tubular cristae are present, but not plastids; the nuclei show open orthomitosis during binary fission.

1991 October 3, Michael A. Sleigh, Protozoa and Other Protists, Cambridge University Press, →ISBN, page 139:

In both closed intranuclear pleuromitosis and orthomitosis, the spindle remains entirely within the nucleus, though its positioning is different.

2010 December 7, Bernd Schierwater, Rob Desalle, editors, Key Transitions in Animal Evolution, CRC Press, page 12:

(cytology) A form of mitosis characterized by an axial, central, symmetric, and bipolar spindle.


VEXAS

First discovered in October 2020, with the report from The New England Journal of Medicine and identified by a multidisciplinary team of scientists (see quotations below).

Using a genotype-driven approach, we identified a disorder that connects seemingly unrelated adult-onset inflammatory syndromes. We named this genetic disorder the VEXAS syndrome, which is caused by myeloid-restricted somatic missense mutations in UBA1.

2020 October 27, David B. Beck, Marcela A. Ferrada, Keith A. Sikora, Amanda K. Ombrello, et alia, “Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease”, in New England Journal of Medicine, volume 383, →DOI:

Additionally, patients with VEXAS suffer from a spectrum of hematologic problems, including macrocytic anemia, thrombocytopenia, thromboembolic disease, and progressive bone marrow failure, which can evolve to hematologic malignancy

2021 July 1, Peter C. Grayson, Bhavisha A. Patel, Neal S. Young, “VEXAS syndrome”, in Blood, volume 137, number 26, →DOI, page 3591:

The researchers note that a diagnosis based on symptoms alone could easily miss cases of VEXAS that would be caught by UBA1 testing.

2023 February 14, Vicki Contie, “VEXAS syndrome more common than realized”, in National Institutes of Health:

(medicine, biology) An autoimmune disease that causes inflammation in the body and mostly affects men.


KTS

Klippel-Trénaunay syndrome
Klippel-Trénaunay syndrome#English

(medicine) Initialism of Klippel-Trénaunay syndrome.


CAPD

(medicine, nephrology) Initialism of continuous ambulatory peritoneal dialysis.


high-fiber

en-adj

high-fiber (comparative higher-fiber, superlative highest-fiber)

higher-fiber (comparative)
highest-fiber (superlative)

(medicine, nutrition) Consisting of a high amount of dietary fiber.


time to progression

en-noun

time to progression (countable and uncountable, plural times to progression)

(medicine, pathology) The length of time from the moment of diagnosis or the commencement of treatment for a disease until the moment the disease begins to worsen or spread to other parts of the body.


HV conduction time

HV conduction time (countable and uncountable, plural HV conduction times)

(medicine, cardiology) The amount of time from the commencement of the first high-frequency component of the bundle of His electrogram to the commencement of the ventricular electrogram.


psychophysical time

psychophysical time (usually uncountable, plural psychophysical times)

(physiology) The amount of time required for the mind to transform a sensory impression into a motor impulse.


WHIM syndrome

Short for warts, hypogammaglobulinemia, immunodeficiency, myelokathexis.

(medicine) A rare congenital immunodeficiency disorder characterized by chronic noncyclic neutropenia.


forced expiratory time

forced expiratory time (countable and uncountable, plural forced expiratory times)

(medicine, pulmonology) The time interval between the beginning and the end of expiration, measured in seconds.


breastsleeping

Compound of breast + sleeping. Coined by American biological anthropologist James J. McKenna in 2014.

coinage

Chris sleeps right through while I put an arm around Tabitha while I'm feeding and keep the duvet down. I have woken up once or twice and panicked - that's what I don't like about breastsleeping. I stopped breastfeeding Henry around nine months. We had to do controlled crying so he would stay in his cot at night. It took four nights of screaming, which was horrific, but he's been an absolute dream ever since.

2017 March 14, Tamsin Kelly, quoting Charlotte Catton, “Breastsleeping: Is This How New Mums Can Get More Sleep?”, in The Huffington Post, archived from the original on 2021-10-23:

What if objects had an active role in shaping our health behaviors? Using my experience breastfeeding my baby, I explore this question through a journey from strict adherence to standard biomedical advice for safe infant sleep to heading the urgings of my body, specifically that of breastmilk, which I come to see as playing an agentic role in my practice of "breastsleeping."

2018 June 5, Jennifer Woody Collins, “Fluid Materiality in Health Communication”, in Health Communication, volume 34, number 11, Hillsdale, N.J.: L. Erlbaum Associates, →DOI, →ISSN, →OCLC, page 1377, column 1:

"Breastsleeping"—a combination of co-sleeping and breastfeeding— is our species' heritage.

2022 March 6, Darcia F. Narvaez, “Safe Infant Sleep and Breastfeeding Are Partners”, in Psychology Today, New York, N.Y.: Sussex Publishers, →ISSN, →OCLC, archived from the original on 2024-05-04:

(medicine, neologism) The practice where a mother cosleeps with her baby while breastfeeding.


holding time

en-noun

holding time (countable and uncountable, plural holding times)

(medicine, hematology) Of a blood or sample test, the elapsed amount of time from the moment of collection to the moment of the initiation of the preparation or analysis.


Vrolik's Syndrome

osteogenesis imperfecta
osteogenesis imperfecta#English

(pathology) Synonym of osteogenesis imperfecta


P-A conduction time

(medicine, cardiology) The time from the onset of the P wave to the onset of the atrial electrogram, normally 27 ± 18 ms.


P-H conduction time

(medicine, cardiology) The time from the onset of the P wave to the first high-frequency component of the bundle of His electrogram, normally 119 ± 38 ms.


tissue thromboplastin inhibition time

tissue thromboplastin inhibition time (uncountable)

(medicine, hematology) A modification of the prothrombin time test in which thromboplastin, a reagent, is diluted, and hence the phospholipid concentration is reduced.


thrombin time

thrombin time (countable and uncountable, plural thrombin times)

(medicine, hematology) A blood test that measures the amount of time required for a clot to form in the plasma of a blood sample containing an anticoagulant, after an excess of thrombin has been added.


clot retraction time

clot retraction time (plural clot retraction times)

(medicine, hematology) A measure of the amount of time required for a blood clot to retract from the walls of a test tube.


clotting time

clotting time (countable and uncountable, plural clotting times)

(medicine, hematology) A general term for the amount of time required for a blood sample to coagulate.


colonic transit time

colonic transit time (countable and uncountable, plural colonic transit times)

(medicine, gastroenterology) The amount of time required for a substance to travel through the colon.


margin of safety

margin of safety (plural margins of safety)

(medicine) The difference between a therapeutic dose of a medication and a toxic dose.


recognition time

recognition time (countable and uncountable, plural recognition times)

(medicine, physiology) The time interval between the moment of the application of a stimulus and the moment of the recognition of its nature.


step time

step time (countable and uncountable, plural step times)

(medicine, sports medicine) Of a gait cycle, the moment in time from the initial contact of one foot to the moment in time of the initial contact of the opposite foot.


sinoatrial conduction time

sinoatrial conduction time (countable and uncountable, plural sinoatrial conduction times)

(medicine, cardiology) The amount of time from the activation of the sinus to local atrial activation in the region surrounding the sinoatrial node.


sinoatrial recovery time

sinoatrial recovery time (countable and uncountable, plural sinoatrial recovery times)

(medicine, cardiology) The time interval from the moment of the last paced P wave to the moment of the first succeeding spontaneous P wave, resulting from activation of the sinoatrial node.


mitral annulus

(anatomy, cardiology) A band of tissue to which the mitral valve leaflets are attached.


intra-atrial conduction time

intra-atrial conduction time (countable and uncountable, plural intra-atrial conduction times)

(medicine, cardiology) The amount of time between the beginning of the P wave in the surface ECG and the top of the A wave, as recorded from the tissue Doppler imaging from the left atrial free wall next to the mitral annulus.


median survival time

median survival time (countable and uncountable, plural median survival times)

(medicine, pathology) The length of time from either diagnosis or treatment in which one half of a sample of patients with a given disease are found to be, or expected to be, still alive.


median effective time

median effective time (countable and uncountable, plural median effective times)

(medicine, pathology) The total amount of time, usually measured in days, required to reach a complete recovery in 50% of a sample of patients.


half-relaxation time

half-relaxation time (countable and uncountable, plural half-relaxation times)

(medicine, myology) The amount of time required by the muscle to relax from the peak torque to fifty percent of its peak value.


peak torque

(medicine, myology) The single highest torque output of a joint produced by a muscular contraction as the limb moves through the range of motion.


Achilles tendon reflex time

Achilles tendon reflex time (countable and uncountable, plural Achilles tendon reflex times)

First use appears c. 1934 in medical literature, although the exact date of its first use is uncertain.

half-relaxation time
half-relaxation time

(medicine, endocrinology) A measurement of the half-relaxation time of the Achilles tendon, used to diagnose disorders of the thyroid.


A wave

(medicine, cardiology) A wave on an electrocardiogram representing the upward deflection in the right atrial pressure occurring during right atrial contraction.


conduction time

conduction time (countable and uncountable, plural conduction times)

(biology, neurology) The total amount of time required for a signal to travel from its starting point to its target.

(biology, neurology) The numerical difference between the latencies at the first recording electrode for each position.


APEX time

(pathology, nephrology) An indication of the optimal dwell time for ultrafiltration.


balling gun

It is very easy to misuse the balling gun and cause a serious "choke" in the horse or damage to the back of the throat.

2006, T. A. Landers, Professional Care of the Racehorse, page 253:

Before passing a balling gun into the patient's oral cavity, a quick assessment of the patient's size is mandatory.

2007, Thomas J. Divers, Simon F. Peek, Rebhun's Diseases of Dairy Cattle, page 21:

This instrument is available in various sizes for use in different species. Cattle require a balling gun with a large head and long handle, with a metal or flexible plastic head.

2016, Margi Sirois, Principles and Practice of Veterinary Technology, page 673:

(veterinary medicine) A device for forcing a pill or bolus of medicine down the throat of an animal.


balling-iron

Named for its original use in forcing open the mouth of an animal for balling.

After a due examination of the mouth has been made, and we have selected the tooth to be operated upon, the animal should be restrained by means of a twitch, and a balling-iron ought then to be placed in the mouth . The common open balling-iron will answer the purpose, but the one I would recommend you to use is that invented by Mr. Varnell .

1851, The Veterinarian: A Monthly Journal of Veterinary Science, page 635:

It is necessary at times to give a medicinal ball to a horse, and as few grooms are expert at administering a ball without assistance, a balling-iron affords them that assistance.

1858, James Slight, Robert Scott Burn, Henry Stephens, The Book of Farm Implements and Machines, page 532:

Every groom should know how to give a ball, which is managed either with or without a balling-iron, an instrument which is seldom wanted , and which sometimes occasions considerable mischief to the roof of the horse's mouth .

1873, George Armatage, The horse, page 158:

The man using a balling-iron has, therefore, to guard himself from blows rapidly dealt with the fore hoofs of a desperate animal.

1876, Edward Mayhew, Mayhew's Illustrated Horse Management, page 42:

(veterinary medicine) A piece of shaped metal that forces the mouth of an animal to stay open.


barography

(see title)

1980, M. Springhorn, L. Vistnes, L.J. Leifer, “The use of optical barography for the study of some aspects of pressure sore etiology .”, in Proceedings of the American Society of Plastic Surgeons, volume 9:

(medicine) The measurement of exerted pressure by means of a barograph.


proemetic

en-adj

proemetic (comparative more proemetic, superlative most proemetic)

more proemetic (comparative)
most proemetic (superlative)

(pharmacology) That induces emesis (vomiting).


proemetic

(pharmacology) An agent that induces emesis (vomiting).


chromoscopy time

en-noun

chromoscopy time (countable and uncountable, plural chromoscopy times)

(medicine, pathology, gastroenterology) The elapsed time between the intramuscular injection of a dye and its appearance in the gastric secretion.


Anrep effect

Named after Russian physiologist Gleb von Anrep, who described it in 1912.

(cardiology) An autoregulation method in which myocardial contractility increases with afterload.


MFDS

alternative medicine
alternative medicine

magnetic field deficiency syndrome#English

(alternative medicine) Initialism of magnetic field deficiency syndrome.


Bowditch effect

Bowditch effect (plural Bowditch effects)

Named after Henry Pickering Bowditch who first observed the effect in 1871.

(medicine) The autoregulation process by which myocardial tension increases with an increase in heart rate.


ceiling effect

(pharmacology) The process of increasing doses of a given medication to have progressively smaller incremental effect.


time delay toxin activation

(oncology, pharmacology) A process for producing a class of chemotherapy drugs which can be administered in a nontoxic form and, subsequent to a time delay, allows for a differential concentration in the target cancer or invasive tissues or cells, minimizing the toxicity to healthy cells, thereby reducing the adverse side effects of chemotherapy.


revulsionary

en-adj

revulsionary (comparative more revulsionary, superlative most revulsionary)

more revulsionary (comparative)
most revulsionary (superlative)

(medicine) Exhibiting or relating to revulsion.


Down syndrome regression disorder

en-noun

Down syndrome regression disorder (uncountable)

(neurology) A strong cognitive regression affecting people with Down syndrome.


Eagle effect

Named after Harry Eagle who first described it.

(microbiology, pharmacology) A phenomenon observed in which higher concentrations of antibiotics paradoxically improve bacterial survival.


Fåhræus-Lindqvist effect

Fåhræus-Lindqvist effect (plural Fåhræus-Lindqvist effects)

Named after Swedish scientists Robin Fåhræus and Johan Torsten Lindqvist} who first reported the effect.

(physiology) The phenomenon in which the viscosity of blood changes with the diameter of the tube it travels through, when the diameter is between 10 and 300 micrometers.


Fåhræus effect

Named after Swedish scientist Robin Fåhræus.

(physiology) The decrease in average concentration of red blood cells in human blood as the diameter of the glass tube in which it is flowing decreases.


Fink effect

Named after British physicial Bernard Raymond Fink, who first explained the effect in 1955.

(medicine) The temporary increase in both the concentrations and partial pressures of oxygen and carbon dioxide in the alveoli when water-soluble gases (e.g. nitrous oxide) are breathed in large quantities so they can be dissolved in body fluids rapidly.


Haldane effect

Named after John Scott Haldane who first discribed the effect.

(hematology) The ability of hemoglobin to carry increased amounts of carbon dioxide in the deoxygenated state as opposed to the oxygenated state.


late effect

(medicine) A condition that appears after the acute phase of an earlier, causal condition has run its course.


maternal effect

maternal effect (plural maternal effects)

(evolutionary theory, genetics) A situation where the phenotype of an organism is determined not only by the environment it experiences and its genotype, but also by the environment and genotype of its mother.


second gas effect

second gas effect (plural second gas effects)

Coordinate term: concentration effect

(medicine) A phenomenon in which a rapid uptake of a large volume of a gas (e.g. nitrous oxide) taken up from alveoli into pulmonary capillary blood leads to an increase in the concentration of gases remaining in the alveoli.


concentration effect

concentration effect (plural concentration effects)

Coordinate term: second gas effect

(medicine) The increase in the (alveolar concentration) / (inspired concentration) ratio as the inspired concentration of the gas (e.g. nitrous oxide) is itself increased.


thymus gland

(anatomy, immunology) A ductless gland, consisting mainly of lymphatic tissue, located behind the top of the breastbone. It is most active during puberty, after which it shrinks in size. It plays an important role in the development of the immune system and produces lymphocytes.


Somogyi effect

Named after Hungarian-American biochemistry professor Michael Somogyi.

(health) A rebounding high blood sugar (hyperglycemia) in the morning as a response to low blood sugar (hypoglycemia) at night.


antifebrin

Old trade name. Compare anti- and febrile.

(historical, medicine) Acetanilide used as an antipyretic.