chloroformist

But his whole account of the correspondence between the chloroformist, by profession, and our colleague is erroneous.

1851 December 6, Homeopathic Times, volume 3, page 283:

This must be a result of the quality of the chloroform, of the quantity used in a given time, of the mental and bodily condition of the patient, of the care and skill of the chloroformist, and of the patience of the surgeon who has to operate; for if he be in a hurry, and pull out his watch, and if the chloroformist take the hint, and push the vapour suddenly, the patient is in imminent risk.

1865, Robert Druitt, The Surgeon's Vade Mecum: A Manual of Modern Surgery, page 721:

In the Lancet cases the methods of giving the anaesthetic were almost uniformly dangerous even in the hands of the most expert and experienced chloroformist.

1897, British Journal of Dental Science and Prosthetics, page 969:

(medicine, archaic) One who uses chloroform as an anaesthetic.


chloroformism

(medicine, archaic) addiction to chloroform


OAB

overactive bladder
overactive bladder#English

(pathology) Initialism of overactive bladder.


crusader complex

en-noun

crusader complex (plural crusader complexes)

(psychoanalysis) A delusional state where the subject believes that he or she is struggling for a just and noble cause.


intrabrachial

The sample size calculation was based on the following assumptions: in previous studies from our own group, we found that the vasodilator response to the intrabrachial administration of adenosine averages 2.8±0.6, 4.4±1.0, 9.0±1.7 ml/min per dl of forearm volume for 0.5, 1.5, and 5.0 μg/min/dl, respectively (mean±SEM, n = 8).

2015 October 29, “Ticagrelor Does Not Inhibit Adenosine Transport at Relevant Concentrations: A Randomized Cross-Over Study in Healthy Subjects In Vivo”, in PLOS ONE, →DOI:


manubriosternal

(anatomy) Relating to the manubrium and sternum.


VACTERL

Although a single pathogenetic mechanism has not been identified to tie all the manifestations of VACTERL together, recognition of this association is helpful in caring for the neonate and facilitating multidisciplinary care and follow-up.

2014, Richard J. Martin, Avroy A. Fanaroff, Michele C. Walsh, Fanaroff and Martin's Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant, Elsevier Health Sciences, →ISBN, page 1213:

(medicine) Initialism of Vertebral anomalies, Anal atresia, Cardiac defects, Tracheoesophageal fistula and/or Esophageal atresia, Renal and radial anomalies, and Limb defects. (A group of birth defects that tend to occur together).


malariotherapy

(medicine, historical) The intentional infection of a syphilis patient with malaria in order to induce a fever.


cephalopolysyndactyly

From cephalo- + polysyndactyly or cephalo- + poly- + syn- + dactyl + -y.

Greig cephalopolysyndactyly syndrome

(pathology, teratology) A disorder that affects development of the limbs, head, and face.


iridesis

(surgery) The ligature of a portion of the iris brought out through an incision in the cornea.


irideremia

(medicine) Total or partial absence of the iris of the eye.


ischiocele

(medicine) hernia through the sciatic notch


echophony

(medicine, dated) An echo of a vocal sound in auscultation of the chest.


lymphagogic

en-adj

lymphagogic (comparative more lymphagogic, superlative most lymphagogic)

more lymphagogic (comparative)
most lymphagogic (superlative)

(immunology, physiology) Stimulating the flow of lymph.


palatinoid

Former trade name. See palatable and -oid.

(medicine, dated) A form of envelope or capsule used for the administration of bitter or unpleasant-tasting drugs.


parasyphilitic

(medicine, archaic) Having or relating to parasyphilis.


paruria

(medicine) Any disorder relating to urination.


addiment

en-noun

addiment (countable and uncountable, plural addiments)

Learned borrowing from Latin additamentum (“an increase”).

lbor

(immunology, archaic) Synonym of complement


alexipharmac

Borrowed from Middle French alexipharmaque (modern French alexipharmaque (archaic)), and from its etymon Latin alexipharmacon (“antidote”) (whence Late Latin alexipharmacum), from Ancient Greek ἀλεξῐφᾰ́ρμᾰκον (alexĭphắrmăkon, “antidote; (generally) remedy; charm, spell”), a noun use of the neuter of ἀλεξῐφᾰ́ρμᾰκος (alexĭphắrmăkos, “acting as an antidote”), from ἀλέξειν (aléxein) (the active infinitive of ἀλέξω (aléxō, “to defend, guard, protect; to help; to keep off, turn aside, ward off”), ultimately from Proto-Indo-European *h₂lek- (“to protect”)) + φάρμᾰκον (phármăkon, “drug, whether healing or poisonous; charm, potion, spell; colour, dye”) + -ος (-os, suffix forming certain types of adjectives).

der

ἀλεξῐφᾰ́ρμᾰκον

/əˌlɛksɪˈfɑːmæk/

/əˌlɛksəˈfɑɹmæk/

(pharmacology, chiefly archaic or historical) A medical remedy for protecting the body, or an antidote, against a harmful substance, especially a poison or venom (specifically, that of a snake); an alexipharmic, an antidote.

alexipharmaque

medical remedy for protecting the body, or an antidote, against a harmful substance, especially a poison or venom — see also antidote


alexipharmac

en-adj

alexipharmac (comparative more alexipharmac, superlative most alexipharmac)

more alexipharmac (comparative)
most alexipharmac (superlative)

Borrowed from French alexipharmaque (archaic), and from its etymon Late Latin alexipharmacus, from Ancient Greek ἀλεξιφάρμακος (alexiphármakos) (see etymology 1).

der

ἀλεξιφάρμακος

/əˌlɛksɪˈfɑːmæk/

/əˌlɛksəˈfɑɹmæk/

(pharmacology, chiefly archaic or historical) Of or pertaining to an alexipharmac; also, acting as an alexipharmac by protecting against or warding off the ill effects of a harmful substance, especially a poison or venom; alexipharmic.

alexipharmaque

of or pertaining to an alexipharmac; acting as an alexipharmac


aluminosis

(pathology) A disease of the lungs caused by aluminum dust.


beige fat

From being a color between brown and white, closer to white.

(anatomy, physiology) A form of brown fat which can function akin to white fat under normal circumstances, but can function as brown fat under cold conditions.


end-foot

(neuroanatomy) the enlarged end of a nerve fiber that terminates adjacent to the dendrite of another nerve cell; a terminal button.


BCVA

Best Corrected Visual Acuity
Best Corrected Visual Acuity#English

(medicine) Initialism of Best Corrected Visual Acuity.


(medicine) A subtype of the species Influenzavirus A (avian influenza virus or bird flu virus), which infects a wide variety of birds and may cause mild symptoms in humans.


chronic wasting disease

(veterinary, pathology) A transmissible spongiform encephalopathy found in deer, typified by chronic weight loss leading to death.


superspreading

LL-Q1860 (eng)-Flame, not lame-superspreading.wav

Our findings indicate that superspreading is a normal feature of disease spread[…]

2005 November 17, J. O. Llloyd-Smith et al., “Superspreading and the effect of individual variation on disease emergence”, in Nature, volume 438, →DOI, pages 355–359:

We found that superspreading has overwhelmingly contributed to the transmission of SARS-CoV-2 in the city overall. Of the 349 local cases we identified — the remaining 689 cases were imported from other territories — 196 were linked to just six superspreading events.

2020 June 2, Dillon C. Adam, Benjamin J. Cowling, “Just Stop the Superspreading”, in New York Times:

(medicine, epidemiology) The spreading of an infection to many other people from a single individual.


venously

(anatomy, medicine) In terms of, or by means of, the vein.


amaril

(obsolete, medicine) The toxin of Bacillus icteriodes, at one time asserted to be the specific organism of yellow fever.


systemic exertion intolerance disease

en-noun

systemic exertion intolerance disease (uncountable)

chronic fatigue syndrome
chronic fatigue syndrome#English

(pathology) Synonym of chronic fatigue syndrome


SEID

systemic exertion intolerance disease#English

(pathology) Abbreviation of systemic exertion intolerance disease.


ME/CFS

myalgic encephalomyelitis
myalgic encephalomyelitis#English

(pathology) Initialism of myalgic encephalomyelitis/chronic fatigue syndrome.


DIC

(medicine) Initialism of disseminated intravascular coagulation.


rifaximin

(pharmacology) A semisynthetic antibiotic based on rifamycin.


ERG

(ophthalmology) Initialism of electroretinogram.


antiaggregation

(medicine) Prevention of the aggregation of platelets.

antiagregació

prevention of the aggregation of platelets


valvulogenesis

(physiology) Generation and development of the valves of the heart


chordamesoderm

(anatomy) The axial mesoderm, which lies along the central axis under the neural tube and gives rise to the notochord.


LGN

lateral geniculate nucleus
lateral geniculate nucleus#English

(neuroanatomy) Initialism of lateral geniculate nucleus.


agnosy

agnosy (countable and uncountable, plural agnosies)

This "mimic agnosy" will be removed only through very prolonged maturation and learning.

1975, Martha Davis, Recognition of facial expression, page 17:

Music perception disorders from neurological origin (the 3 levels of musical perception désintégration considered as auditory agnosy).

1985, Psychology, psychopathology, psychiatry, page 467:

Neuropsychological examination performed two weeks after the stroke revealed normal speech and auditory verbal comprehension and no number dyslexia, acalculia, colour and digital agnosy.

1993, The Italian Journal of Neurological Sciences: Supplementum:

Somato-agnosies vary widely, and somato-paraphrenia is one of the examples of this inability to recognize a part of the body as one's own.

2010, JL Petit, “A Husserlian, Neurophenomenologic Approach to Embodiment”, in Handbook of Phenomenology and Cognitive Science:

The problems related to the visual-spatial difficulties are due to the loss of spatial references, either due to problems of the visual field loss or perceptive problems (agnosy), attention problems or difficulties of the executive function, which cause an inefficient search of information.

2010, L Gangoiti, IM Villafruela, “Initiation of the most appropriate post-stroke rehabilitation”, in Diabetologḯa, volume 26:

These advantages also play a role in treatment for special indication such as in patients with neurological problems (e.g. Parkinson's disease), in whom a total replacement leads to a worsening of the underlying disease whereas compartmental reconstruction avoids the effect of somato-agnosy (loss of sensation of a body part).

2013, Norberto Confalonieri, Sergio Romagnoli, Small Implants in Knee Reconstruction, →ISBN, page 3:

(countable, neurology) A deficit in the ability to perceive.

Finally, optic aphasics are usually described as being unimpaired in everyday life, whereas agnosies are often noticeably handicapped by their inability to recognize objects, people, and locales.

2000 October, M Sitton, MC Mozer, MJ Farah, “Superadditive effects of multiple lesions in a connectionist architecture: Implications for the neuropsychology of optic aphasia.”, in Psychological Review, volume 107, number 4:

(countable, neurology) A patient suffering from an agnosy.


besifloxacin

From [Term?] + -floxacin (“nalidixic acid derivative”).

af

(pharmacology) A particular fluoroquinolone antibiotic.


backpropagational

(computing, neurology) Relating to backpropagation.


fostemsavir

From fos- (“phosphorous derivative”) + temsavir.

(pharmacology) An experimental HIV entry inhibitor that is a prodrug of temsavir.


pradofloxacin

(pharmacology) A particular veterinary antibiotic of the fluoroquinolone class.


syphilomania

(medicine, dated) syphilophobia in people who do not already have syphilis


cricoidectomy

(surgery) excision of the cricoid cartilage


operational exhaustion

(military, psychiatry) The acute psychological trauma experienced in combat environments which can lead to combat fatigue.


allolalia

(neurology) Any speech disorder resulting from cerebral damage.


arthritism

(pathology) A predisposition to gout or to arthritis.


IPV

inactivated polio vaccine
w:inactivated polio vaccine

(medicine) Initialism of inactivated polio vaccine.


erythrophagocytosis

Thus, consistent with its known function in regulating RBC phagocytosis, Hu5F9-G4 caused a transient anemia, likely due to erythrophagocytosis, but was otherwise well-tolerated.

2015 September 22, “Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential”, in PLOS ONE, →DOI:

(cytology, immunology) The phagocytosis of erythrocytes


palirrhea

Complications such as palirrhea and diarrhea occurring after operation may further aggravate dystrophy.

2015 September 22, “A Novel Inflammation-Based Prognostic Score, the C-Reactive Protein/Albumin Ratio Predicts the Prognosis of Patients with Operable Esophageal Squamous Cell Carcinoma”, in PLOS ONE, →DOI:


subconsomic

To narrow down the region that contains the genetic loci involved in the aggression-eliciting effects on Chr 15, we established a panel of subconsomic strains of MSM Chr 15.

2015 September 22, “Mapping of Genetic Factors That Elicit Intermale Aggressive Behavior on Mouse Chromosome 15: Intruder Effects and the Complex Genetic Basis”, in PLOS ONE, →DOI:

(genetics, of strains) congenic and without chromosome substitution


ISI

Coordinate term: INR

international sensitivity index
w:international normalized ratio

(hematology) Initialism of international sensitivity index.


ignatia

(homeopathy) A homeopathic remedy made from the plant Strychnos ignatii.


amphoriloquy

Amphoric voice, or amphoriloquy of cavities. — The cavernous direct pectoriloquy, or thoracic voice of the third stage of phthisis, occasionally is found to partake of a hollow vessel, pitcher, or amphoric tone.

1861, Somerville Scott Alison, The physical examination of the chest in pulmonary consumption, page 204:

Amphoric echo is simply the reverberation of the voice, cough, or breath sound, in such a cavity. The same sort of cavity is required for amphorophony or amphoriloquy as in the case of amphoric resonance on percussion, amphoric respiration, and metallic or amphoric tinkle.

1889, Richard Channing Moore Page, A Handbook of physical diagnosis of diseases of the organs of respiration:

(medicine) A condition where the voice is characterized by amphoric sound over the patient's lung cavity.


chondronecrosis

We have identified Staphylococcus agnetis as significantly involved in bacterial chondronecrosis with osteomyelitis (BCO) in proximal tibia and femorae, leading to lameness in broiler chickens in the wire floor system.

2015 November 26, “Genome Analysis of Staphylococcus agnetis, an Agent of Lameness in Broiler Chickens”, in PLOS ONE, →DOI:


dactylion

Two measurements were taken: 1) the sitting height (SitH1), measured as the vertical distance from the vertex of the head to the floor; 2) the vertical grip reach from a seated position (SitH2), measured as the maximal distance from the tip of the dactylion III to the floor, with the upper arms extended overhead as much as possible (Fig 3).

2015 November 26, “Physique and Performance of Young Wheelchair Basketball Players in Relation with Classification”, in PLOS ONE, →DOI:


extravesicular

The normalized fluorescence change (ΔF/ΔF max ) was determined by dividing the observed fluorescence change (ΔF) by that induced by adding 1% β-OG to the extravesicular medium (ΔF max ).

2015 November 26, “A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters”, in PLOS ONE, →DOI:


merangiotic

Due to the merangiotic nature of rabbit retina, most of the blood supply of the inner retina is derived from the choriocapillaris [47 ], which would likely lead to rapid retinal damage, if blocked by a non-permeable implant.

2015 November 26, “Ultrathin Polyimide Membrane as Cell Carrier for Subretinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigment Epithelium”, in PLOS ONE, →DOI:

(ophthalmology) Having blood vessels localized to a specific region of the retina.


aneusomaty

Environmental stress-induced inter and intra individual variability in chromosome number, aneuploidy and aneusomaty were early found in D.

2015 September 23, “Molecular Cytogenetic Analysis of Deschampsia antarctica Desv. (Poaceae), Maritime Antarctic”, in PLOS ONE, →DOI:

(genetics) Chromosome variation within an individual organism.


endocortical

Histological measurements of the endocortical bone of the femur also began two visual fields below the growth plate and were continued to the diaphysis, with the diaphysis defined as the midway point between the ends of the femur.

2015 September 23, “Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone”, in PLOS ONE, →DOI:

(anatomy) On the inside of the cortex (especially of bone)


immunosensitive

en-adj

immunosensitive (comparative more immunosensitive, superlative most immunosensitive)

more immunosensitive (comparative)
most immunosensitive (superlative)

Hyaline cells exhibit α-CasPPO-hemo immunostaining only at postmolt stage (Fig 5A and 5B ; n = 5–6), while semigranulocytes are immunosensitive only at early premolt and postmolt stages.

2015 September 23, “The Involvement of Hemocyte Prophenoloxidase in the Shell-Hardening Process of the Blue Crab, Callinectes sapidus”, in PLOS ONE, →DOI:

(immunology) sensitive to allergens; allergic


pycnomorphic

(cytology) Having a compact arrangement of stainable parts


retinochoroiditis

A systematic review and meta-analysis on the treatment and control of toxoplasmic retinochoroiditis has been published, and there is a lack of evidence to support routine antibiotic treatment being effective for acute Toxoplasma retinochoroiditis [18, 19 ].

2015 September 23, “A Systematic Review and Meta-Analysis of the Efficacy of Anti- Toxoplasma gondii Medicines in Humans”, in PLOS ONE, →DOI:

(pathology) inflammation of the retina and choroid


biophysiochemical

Whilst it is possible that assay bias has occurred due to differences in soil biophysiochemical properties between the high and low prevalence site, previous seeding experiments into soil from the low-prevalence site have not provided evidence of assay inhibition.

2015 September 24, “Environmental Attributes Influencing the Distribution of Burkholderia pseudomallei in Northern Australia”, in PLOS ONE, →DOI:

(biology, physiology, chemistry) biophysiological and chemical


intraoperation

Similar to 18 F-tLyP-1, the tumor/brain ratios of FAM-tLyP-1 was also high, indicating both molecular reagents could likely by used to identify glioma microinvasions before the surgery and intraoperation to guide the resection of malignant glioma.

2015 September 24, “Use of Labelled tLyP-1 as a Novel Ligand Targeting the NRP Receptor to Image Glioma”, in PLOS ONE, →DOI:


periinterventional

However, not only metabolic disturbances but also periinterventional complications such as wound healing, deep vein thrombosis and delayed graft function are more frequent in obese renal allograft recipients [48 ].

2015 September 24, “Diabetes Mellitus and Prediabetes on Kidney Transplant Waiting List- Prevalence, Metabolic Phenotyping and Risk Stratification Approach”, in PLOS ONE, →DOI:


arthrocele

The CIA animal model is characterized by arthrocele, synovitis, cartilage destruction and bone erosion [25 ], and is generally considered an adequate representation of the pathogeneic processes of human RA.

2015 September 25, “Anti-Arthritic Effect of Chebulanin on Collagen-Induced Arthritis in Mice”, in PLOS ONE, →DOI:

(pathology) The swelling of a joint; a hernia of the synovium through the capsule of a joint


benadrostin

As illustrated in Fig 4B and 4C, respectively, the loss of an amide group was corroborated to m/z 152.035 for 2,3-dihydroxybenzamide as indicated by the fragment ion at m/z 109.03 [C 6 H 5 O 2 ] and m/z 178.015 for benadrostin that gave a fragment ion at m/z 137.02 [C 7 H 5 O 3 ].

2015 September 26, “Biodiversity, Anti-Trypanosomal Activity Screening, and Metabolomic Profiling of Actinomycetes Isolated from Mediterranean Sponges”, in PLOS ONE, →DOI:

(organic chemistry, medicine) The compound 8-hydroxy-2H-1,3-benzoxazine-2,4(3H)-dione, which is an inhibitor of poly(ADP-ribose) synthetase


craniotomize

en-verb

craniotomize (third-person singular simple present craniotomizes, present participle craniotomizing, simple past and past participle craniotomized)

craniotomizes (present singular third-person)
craniotomizing (participle present)
craniotomized (participle past)
craniotomized (past)

(surgery) To perform or to undergo craniotomy.


dermatophilosis

From Dermatophilus, the causative agent, + -osis.

In Israeli dairy herds, the high prevalence of infectious cutaneous diseases such as dermatophilosis and pseudotuberculosis, caused by Dermatophilus congolensis and Corynebacterium pseudotuberculosis respectively, might be attributed to the extensive adoption of evaporative cooling systems in these herds [10 ].

2015 September 26, “Diversity of Bacterial Biofilm Communities on Sprinklers from Dairy Farm Cooling Systems in Israel”, in PLOS ONE, →DOI:

(pathology) A form of exudative dermatitis found in the tropics


oligodontia

Numerous gene mutations have been association with oligodontia.

2015 September 26, “A Novel AXIN2 Missense Mutation Is Associated with Non-Syndromic Oligodontia”, in PLOS ONE, →DOI:

(pathology) The absence of six or more teeth


Jacob's membrane

en-noun

Jacob's membrane (plural Jacob's membranes)

(anatomy) A layer of rod cells and cone cells in the retina of the human eye.


DNP

DNP (countable and uncountable, plural DNPs)

Doctor of Nursing Practice
Doctor of Nursing Practice#English

(medicine) Initialism of Doctor of Nursing Practice.


antilymphocyte

The high prevalence of CMV infection in our sample may be because most of our patients had received kidneys from deceased donors who underwent polyclonal antilymphocyte globulin induction therapy (Thymoglobulin®), known as one of the primary risk factors for CMV infection [12 ,13 ].

2015 September 30, “Hospital Admission following Acute Kidney Injury in Kidney Transplant Recipients Is Associated with a Negative Impact on Graft Function after 1-Year”, in PLOS ONE, →DOI:

(immunology, of an antibody) That acts against lymphocytes


glycoallergen

(biochemistry, immunology) Any glycoside allergen.


briakinumab

From -kin- (“interleukin”) + -umab (“human monoclonal antibody”).

af

As another interleukin 12/23 antagonist, briakinumab, was withdrawn from further development in part due to concerns about cardiovascular safety, discussion has also emerged on cardiovascular safety of ustekinumab.

2015 December 4, “Patient Preferences for Biologicals in Psoriasis: Top Priority of Safety for Cardiovascular Patients”, in PLOS ONE, →DOI:

rheumatoid arthritis
rheumatoid arthritis

(pharmacology) A human monoclonal antibody being developed to treat rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis.


polygenically

(genetics, mathematics) In a polygenic manner.


periesophageal

CTV was defined as GTV plus a 2.0–5.0 cm craniocaudal margin with a 0.8–1.0 cm lateral margin and the areas at risk for elective nodal regions (such as lower cervical, periesophageal, mediastinal and perigastric LNs).

2015 December 5, “Feasibility of Elective Nodal Irradiation (ENI) and Involved Field Irradiation (IFI) in Radiotherapy for the Elderly Patients (Aged ≥ 70 Years) with Esophageal Squamous Cell Cancer: A Retrospective Analysis from a Single Institute”, in PLOS ONE, →DOI:


endarterectomize

en-verb

endarterectomize (third-person singular simple present endarterectomizes, present participle endarterectomizing, simple past and past participle endarterectomized)

endarterectomizes (present singular third-person)
endarterectomizing (participle present)
endarterectomized (participle past)
endarterectomized (past)

(transitive, surgery) To perform endarterectomy upon.


immunopellet

(immunology) A pellet formed by immunoprecipitation


periaqueduct

Abdominal surgery increased c-Fos in the prelimbic, cingulate and insular cortexes, and autonomic nuclei, such as the bed nucleus of the stria terminalis, central amygdala, hypothalamic supraoptic (SON), paraventricular and arcuate nuclei, Edinger-Westphal nucleus (E-W), lateral periaqueduct gray (PAG), lateral parabrachial nucleus, locus coeruleus, ventrolateral medulla and nucleus tractus solitarius (NTS).

2015 October 1, “Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito”, in PLOS ONE, →DOI:

(neuroanatomy) The area surrounding the cerebral aqueduct


complementology

The chapters from prominent experts cover the essentials as well as the hottest issues in complementology.

2007, Janos Szebeni, The Complement System: Novel Roles in Health and Disease, →ISBN:

This led to many reports of increased frequency of infections among complement-deficient patients and to the legitimization of complementology as a bona fide part of immunology.

2008, Richard A. Kaslow, Janet McNicholl, Adrian V. S. Hill, Genetic Susceptibility to Infectious Diseases, →ISBN, page 156:

Nevertheless, the obvious similarities in killing by complement and by lymphocytes were considered early [126] and led to continuous cross-fecundation between complementology and cellular immunology.

2012, Klaus Rother, Gerd Till, The Complement System, →ISBN, page 239:

(medicine) The branch of immunology that deals with complement (one of four proteolytic cascades in blood).


deleobuvir

From [Term?] + -buvir (“RNA polymerase (NS5B) inhibitor”).

af

(pharmacology) An experimental drug for the treatment of hepatitis C.


cervicocephalic

The ostrich neck was delivered to us decapitated and severed from the rest of the body, thus any anterior (i.e., cervicocephalic) or posterior (i.e., cervicothoracic) air sac diverticula were not present, resulting in incomplete and partially damaged air sacs and their diverticula on the anteriormost and posteriormost ends of the neck.

2015 December 10, “Osteological and Soft-Tissue Evidence for Pneumatization in the Cervical Column of the Ostrich ( Struthio camelus ) and Observations on the Vertebral Columns of Non-Volant, Semi-Volant and Semi-Aquatic Birds”, in PLOS ONE, →DOI:

(anatomy) Relating to the neck and head.


periskeletal

Starting at approximately one month of age and continuing for the next two years, the scleral ossicles of SF elongate via unilateral periskeletal ossification and fuse to form a continuous bony ring that eventually covers 90% or more of the circumference of the eye, while the sclera of CF remain cartilaginous, stop growing, and eventually form a cyst around the degenerating eye.

2015 December 10, “Complex Evolutionary and Genetic Patterns Characterize the Loss of Scleral Ossification in the Blind Cavefish Astyanax mexicanus”, in PLOS ONE, →DOI:


pericryptal

Microdissection was performed using the Leica LMD 6000 microdissector, to obtain the whole crypts, including pericryptal areas, for each sample.

2015 December 10, “Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation”, in PLOS ONE, →DOI:

(anatomy) Around the crypts (small pits or cavities in the body).


oralmost

(anatomy) Located furthest in the oral direction.


mass effect

(medicine) The anatomic and physiological effect that an ectopic mass (such as a tumor, hematoma, or pleural effusion) causes by displacing or pushing against eutopic structures. It may squeeze and thus occlude blood vessels or lymphatic vessels; pinch nerves; disrupt gastrointestinal volume and peristalsis; and so on.


ixekizumab

From [Term?] + -ki- (“interleukin”) + -zumab (“humanized monoclonal antibody”).

More recently, other biological drugs, such as ustekinumab, ixekizumab, tofacitinib, secukinumab and briakinumab, have targeted immunological mediators of the disease.

2015 December 12, “Evolution of Cooperation Patterns in Psoriasis Research: Co-Authorship Network Analysis of Papers in Medline (1942–2013)”, in PLOS ONE, →DOI:

(pharmacology) A humanized monoclonal antibody for the treatment of autoimmune diseases. It works by binding to interleukin 17 and blocking its action.


brodalumab

From -l- (“immunomodulating”) + -umab (“human monoclonal antibody”).

(pharmacology) A human monoclonal antibody designed to treat inflammatory diseases such as psoriasis.


corticogeniculate

(anatomy) Going from the cortex to the geniculate nucleus.


geniculocortical

(anatomy) Going from the geniculate nucleus to the cortex.


NIHL

(pathology) Initialism of noise-induced hearing loss.


frontomedial

It was also shown that gene expression in the rat brain, although similar, differs between cortical regions, with 30 genes found to be enriched in the frontomedial cortex [51 ,52 ].

2015 October 3, “The Effects of Different Repetitive Transcranial Magnetic Stimulation (rTMS) Protocols on Cortical Gene Expression in a Rat Model of Cerebral Ischemic-Reperfusion Injury”, in PLOS ONE, →DOI:

(anatomy) In the front, near the midline


immunoneutralized

(immunology) Modified by immunoneutralization.


logopenia

The other two most frequent neurobehavioral changes besides “incontinence”, i.e., logopenia and apathy, are negative symptoms.

2015 October 3, “The Global Cognition, Frontal Lobe Dysfunction and Behavior Changes in Chinese Patients with Multiple System Atrophy”, in PLOS ONE, →DOI:

(pathology) logopenic progressive aphasia


midsutural

Data suggest slight decreases in markers of proliferation in the periosteal and midsutural areas analyzed.

2015 October 3, “Effects of Citalopram on Sutural and Calvarial Cell Processes”, in PLOS ONE, →DOI:


prelaryngeal

Central lymph nodes were divided into three or four subgroups in some articles: ipsilateral paratracheal, pretracheal, contralateral paratracheal, and prelaryngeal.

2015 October 3, “Risk Factors for Central Lymph Node Metastasis in CN0 Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis”, in PLOS ONE, →DOI:


pretracheal

2015 October 3, Wei Sun, Xiabin Lan, Hao Zhang, Wenwu Dong, Zhihong Wang, Liang He, Ting Zhang, Siming Liu, “Risk Factors for Central Lymph Node Metastasis in CN0 Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis”, in PLOS One, volume 10, number 10, →DOI:

(anatomy, relational) Anterior to the trachea.


Hoffa's fat pad

en-noun

Hoffa's fat pad (plural Hoffa's fat pads)

(anatomy) A cylindrical piece of fat that is situated under and behind the patella bone within the knee.


laparotomize

en-verb

laparotomize (third-person singular simple present laparotomizes, present participle laparotomizing, simple past and past participle laparotomized)

laparotomizes (present singular third-person)
laparotomizing (participle present)
laparotomized (participle past)
laparotomized (past)

(transitive, surgery) To perform laparotomy upon.


frontolateral

Through a frontolateral hole in the skull, a no. 4 Fogarty catheter (Edwards Lifesciences Co, Irvine, USA) was placed in the epidural space and slowly inflated (0.16 ml/min) with saline using a syringe pump (Terufusion, Termo Co, Tokyo, Japan).

2015 October 6, “Anti-Apoptotic Effects of 3,3’,5-Triiodo-L-Thyronine in the Liver of Brain-Dead Rats”, in PLOS ONE, →DOI:


oral candidiasis

en-noun

oral candidiasis (countable and uncountable, plural oral candidiases)

(pathology) Infection on the mucous membranes of the mouth due to yeast of the genus Candida.


peristernal

These authors also observed increased proportions of 18:1 in peristernal adipose tissue of starved reindeer calves.

2015 December 18, “Fatty Acid Composition of Muscle, Adipose Tissue and Liver from Muskoxen ( Ovibos moschatus ) Living in West Greenland”, in PLOS ONE, →DOI:


dodecaploid

(genetics) Having twelve complete sets of chromosomes in a single cell.


immunodensity

immunodensity (countable and uncountable, plural immunodensities)

By contrast, BSSG-fed animals were found to display and increase in immunolabeling for Grp78, with significantly higher immunodensity at 8 and 10 months following initial toxin exposure, relative to controls.

2015 October 7, “The Progressive BSSG Rat Model of Parkinson's: Recapitulating Multiple Key Features of the Human Disease”, in PLOS ONE, →DOI:

western blot analysis
western blot analysis

(immunology) The density of antibodies found during western blot analysis etc.


exocrinopathy

The disease is also characterized by the presence of epithelial cell apoptosis, pathogenic autoantibodies, and overexpression of type I interferon (IFN) [6 ], [7 ], [8 ], which can lead to exocrinopathy and extraglandular organ damage.

2015 October 8, “Growth Arrest-Specific 6 Protein in Patients with Sjögren Syndrome: Determination of the Plasma Level and Expression in the Labial Salivary Gland”, in PLOS ONE, →DOI:

(pathology) Any disease of the exocrine system


hypoleptinemia

(pathology) The presence of a lower than normal amount of leptins in the bloodstream


luseogliflozin

From [Term?] + -gliflozin (“phlorizin derivative”).

af

To evaluate the cardiac safety of luseogliflozin, a thorough QT/QTc study was conducted in healthy Japanese subjects.

2015 October 8, “Randomized, Controlled, Thorough QT/QTc Study Shows Absence of QT Prolongation with Luseogliflozin in Healthy Japanese Subjects”, in PLOS ONE, →DOI:

(pharmacology) The thioglycoside 1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol that is used to treat diabetes


orbitocerebral

Although more gracile, it is clearly homologous to the orbitocerebral vein that is present in some sauropods like Diplodocus longus ([42 ]: fig. 6.9) and Camarasaurus lentus ([42 ]: fig. 6.8).

2015 October 8, “A New Titanosaurian Braincase from the Cretaceous “Lo Hueco” Locality in Spain Sheds Light on Neuroanatomical Evolution within Titanosauria”, in PLOS ONE, →DOI:

(anatomy) Relating to the orbit of the eye and the brain


parasphenoidal

Abbreviations: BP, basipterygoid process; BT, basal tuber; CP, capitate process; CA, crista antotica; CO, crista otosphenoidea; CT, crista tuberalis; FM, foramen magnum; OC, occipital condyle; OF, olfactory fenestra; OR, orbital recess; PP, paroccipital process; PSR, parasphenoidal rostrum; PTF, posttemporal fenestra; SNC, sagittal nuchal crest; STF, supratemporal fenestra; TNC, transverse nuchal crest; V, trigeminal foramen.

(anatomy) Relating to the parasphenoid (bone)


subcondylar

However, in that taxon the surface of the basioccipital between the occipital condyle and the basal tubera is not excavated as in MCCM-HUE-1667 and lacks the subcondylar recess or foramen.


immunoenzymometric

Serum GH and IGF-I levels were measured by an immunoenzymometric assay using the ST AIA-PACK hGH kit (TOSOH Corporation, Tokyo, Japan) and an immunoradiometric assay using “Daiichi” IGF-I IRMA kit (FUJIFILM RI Pharma Co.,Tokyo, Japan), respectively.

2015 October 9, “Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence”, in PLOS ONE, →DOI:

(immunology) Describing the enzymometric analysis of antigens or antibodies


intercodon

Both have (i) slippery sequences (SS) of the form X XXY YYZ (U UUU UUA for HIV-1 and G GGA AAC for PEG10), (ii) different intercodons [26 ] (GGG and UCC respectively), (iii) distinct secondary structures (SStr) (extended stem-loop for HIV-1 and pseudoknot for PEG10), and (iv) the SStr start is within the intercodon in HIV-1, whereas it is two nucleotides downstream of the intercodon in PEG10. […] The different slippery sequences, intercodons, and downstream secondary structures facilitated a frameshift efficiency that was ~2.5-fold higher for PEG10 than for HIV-1 (Fig 1 ).

2015 October 9, “HIV-1 and Human PEG10 Frameshift Elements Are Functionally Distinct and Distinguished by Novel Small Molecule Modulators”, in PLOS ONE, →DOI:

(genetics) The sequence of nucleic acid between specific codons


hematospermia

(pathology) The presence of blood in the semen


hemiatrophy

en-noun

hemiatrophy (countable and uncountable, plural hemiatrophies)

(pathology) atrophy that affects only one half of the body


hemidesmus

(medicine, historical) The dried root of Hemidesmus indicus, from India and used medicinally as a tonic or diuretic.


neuropath

(medicine, dated) A person with neuropathy, perhaps also including (in outdated nosology) a neurosis: someone who has, or is predisposed to, some disease of the nervous system.

(medicine, historical) A physician with specialization in neuropathy, corresponding to today's specialties of neuropathologist or neurologist: one who focuses on nervous conditions in pathology.


neuromimesis

(medicine, archaic) hysterical or neurotic simulation of disease


gasserectomy

(surgery) The excision of the Gasserian ganglion.


palpebronasal

(anatomy) Relating to the nose and the eyelids.


nasoplasty

nasoplasty (countable and uncountable, plural nasoplasties)

Alef, Matthew; Irwin, Chetan; Smith, Darren; Afifi, Ahmed; Jiang, Shao; Vecchione, Lisa; Ford, Matthew; Decesare, Gary E; Deleyiannis, Frederic W.-B; Losee, Joseph E (2009). "Nasal Tip Complications of Primary Cleft Lip Nasoplasty". Journal of Craniofacial Surgery. 20 (5): 1327–33. doi: 10.1097/SCS.0b013e3181ae4115. PMID 19816250. "Complications of primary nasoplasty, at the time of definitive primary cheiloplasty, are underreported in the literature."

McDaniel, Jarred M; Alleyne, Brendan; Gosain, Arun K (2013). "Secondary Cleft Nasoplasty at Primary School Age". Plastic and Reconstructive Surgery. 132 (4): 933–43. doi: 10.1097/PRS.0b013e3182a053f1. PMID 24076684. "Fifty-three patients underwent secondary cleft nasoplasty with resorbable plate placement as a columellar strut."

(surgery, uncountable) A type of plastic surgery that is used to improve the function (reconstructive surgery) or appearance (cosmetic surgery) of a person's nose.


hemiliver

If this were so, he argues the left hemiliver would be deprived of depatotrophic factors, thought to come principally from the pancreas.

1987, Roderick N. M. MacSween, Pathology of the Liver, page 12:

The main portal scissura (Cantle's line), which divides the liver into left and right hemilivers, lies along a line 75° from the horizontal plane opened to the left of the ex vivo liver, beginning at the IVC.

2004, James L. Abbruzzese, Gastrointestinal Oncology:

In addition, the diseased hemiliver acts as a transitory auxiliary liver that assists the growing FLR in metabolic, synthetic and detoxifying functions for the first and critical week after liver partition.

2015 December 24, “ALPPS Procedure for Extended Liver Resections: A Single Centre Experience and a Systematic Review”, in PLOS ONE, →DOI:


heptanucleotide

Van Belkum et al. report one example of a heptanucleotide 5’-GTGATTA-3’ in Helicobacter pylori.

2015 December 23, “Investigation of a Quadruplex-Forming Repeat Sequence Highly Enriched in Xanthomonas and Nostoc sp.”, in PLOS ONE, →DOI:

(genetics) A codon containing seven nucleotides.


trachelo-

Representing the Ancient Greek τράχηλος (trákhēlos, “neck”).

der

trachelacromial, trachelobranchiate, trachelo-bregmatic, tracheloclavicular, trachelomastoid, tracheloccipital, tracheloscapular

(chiefly anatomy) neck or neck-like structure

neck (structure connecting the head to the thorax)

tracheloplasty, trachelorrhaphy, trachelotomy

neck or neck-like structure
cervix uteri


auxeticity

(pathology) The quality of being auxetic (relating to auxesis).


didactylism

(anatomy) The condition of having only two fingers on a hand, or only two toes on a foot.


dysodontiasis

A number of controlled clinical trials showed that meclofenamic acid is an excellent analgesic, offering good tolerability when used in oral surgery, dysodontiasis, avulsion of the third impacted molar, and periodontitis.

1991 January 1, Marcucci M, “Clinical experience in the treatment of dental pain”, in The Clinical Journal of Pain:

(medicine, rare) Difficulty or irregularity in the eruption of the teeth.


dysorexia

(pathology) An impaired or unnatural appetite.


hardware disease

From the fact that in cattle it is usually caused by hardware such as a piece of wire or a fastener (e.g., fence wire, nail, screw).

(animal husbandry, veterinary medicine) Traumatic gastrointestinal puncture and infection in ruminants (especially cattle) and birds that ingest a sharp object (in livestock usually a metal object such as wire or a fastener); in cattle it usually includes reticuloperitonitis and thus in practice is usually metonymically synonymous with traumatic reticuloperitonitis.


obtundity

en-noun

obtundity (usually uncountable, plural obtundities)

[T]here are beings [who] . . . revel, with a lively zest, among all the things that are most foul and loathsome. . . . Sensuality, force of temper, inertness, obtundity of perception, personal idolatry, and the destitution of the higher and better emotions of humanity, are the ingredients of a constitution of this order.

1824, Theophrastus (author), Francis Howell (translator), The Characters of Theophrastus, Josiah Taylor (London), p. 237 (Google preview)

Clinically one sees gradually developing oedema, often a strikingly puffy face, increasing mental obtundity, the patient finally lapsing into confusion and stupor.

1975, George Martin Yuill, The Treatment of Renal Failure, →ISBN, page 24:

The patient goes through the following stages of recovery: unconsciousness (also called paralytic coma), stupor, obtundity, lethargy, confusion (with or without delirium), near lucidity with automatism, and finally full alertness.

2014, David J. Magee, Orthopedic Physical Assessment, →ISBN, page 104:

Collins English Dictionary defines obtundity as the state of "having the senses numbed or less sharp."

2024 January 17, Andrew Barton, “'Obtundity' signs bewilder York residents and visitors”, in BBC News:

(rare, often medicine) The state or characteristic of having dulled senses or limited awareness.


TNC

(immunology) Initialism of thymic nurse cell.


paristhmitis

The melancholy issue of this case, which seemed to the general observer merely an intense form of paristhmitis or tonsillar inflammation, led me to reflect on the probable means of obviating so unfavourable a catastrophe in a disease so apparently slight.

1834 July 7, David Craigie, “Observations, Pathological and Therapeutic, on a particular species of Quinsy or Angina”, in The Edinburgh Medical and Surgical Journal, page 27:


perichord

(anatomy, rare) A membranous sheath around the notochord.


pervigilium

A Pervigilium is sometimes a primary Distemper, without any other evident Sickness causing it; yet so that some bear up under it, without any considerable Disorder […]

1733, John Allen, Synopsis medicinæ: or, a summary view of the whole practice of physick:

Pervigilium, or want of sleep, is a most distressing and alarming symptom in fever, and appears to be the first link of that chain which includes delirium, coma, and effusion[…]there is nothing more indicative of the severity of the disease than the inability to sleep.

1843, W. L. MacGregor, Practical Observations on the Principal Diseases Affecting the Health of the European and Native Soldiers in the North-western Provinces of India, page 44:


noli me tangere

noli me tangere (plural noli me tangeres)

LL-Q1860 (eng)-Vealhurl-noli me tangere.wav

/-ˌmeɪ ˈtɑnd͡ʒəɹeɪ/

Antonio da Correggio
Jesus
Mary Magdalene
Museo del Prado
Vulgate

PIE word
 *ne
From Middle English noli me tangere, noly me tangere (“skin disease of the face; bad-tempered person who should be avoided; personification of wrath”), a learned borrowing from Late Latin nōlī mē tangere (literally “do not touch me”), from Latin nōlī (“do not”) + mē (“me, myself”) + tangere (the present active infinitive of tangō (“to grasp; to touch”)). The phrase is recorded in John 20:17 of the Vulgate, a 4th-century Latin translation of the Bible, as having been spoken to Mary Magdalene by Jesus shortly after his resurrection outside his tomb. The original phrase was the Koine Greek μή μου ἅπτου (mḗ mou háptou, “stop clinging to me”).
Senses 2–5 refer to the literal meaning of the phrase. For example, in the case of sense 4 (“any of various plants with fruits or seed capsules that, when ripe, burst open and discharge their seeds when touched, or with leaves that fold and droop when touched”), the name alludes to the assumption that the plants do not wish to be touched, and react by exploding their fruits or closing their leaves if this happens.

ref

From the collection of the Museo del Prado in Madrid, Spain.

noncog

μή μου ἅπτου

asia josta pysyä loitolla

someone or something to be avoided or not interfered with

kosketusherkkä kasvi

The ſame Maiſter [Jean] Nicot, hauing caused the ſaid hearb [tobacco] to be ſet in his Garden, where it grewe and multiplied maruellouſly, was vppon a time aduertiſed, by one of his Pages, that a young man, of kinne to that Page made a ſaye of that hearbe bruſed both the hearbe and the Juice together vppon an vlcer, which he had vpon his cheeke neere vnto his noſe, comming of a Noli me tangere, which began to take roote already at the griſtles of the Noſe, wherewith hee founde himſelfe meruellouſly eaſed. Therefore the ſayde Maister Nicot cauſed the ſicke young man to bee brought before him, and cauſing the ſaide hearb to be continued to the ſore eight or ten daies, this ſaide Noli me tangere, was vtterly extinguiſhed and healed: […]

1580, Doctor Monardius [i.e., Nicolás Monardes], “Hereafter Followeth a Further Addition of the Hearbe Called Tabaco, Otherwise Called by the Frenchmen Nicotiane, which Hearbe hath Done Great Cures in the Realme of Fraunce and Portugall, as heereafter at Large may Appeare in This Treatise Following”, in John Frampton, transl., Ioyfull Newes out of the Newfound World, […], London: […] [Thomas Dawson for] William Norton, →OCLC, 2nd part, folio 42, verso:

After the ſame manner Ariſtolochia together with Cyperus, healeth the ſtinking and illfavored ulcer of the noſe, called Noli-me-tangere.

1601, C[aius] Plinius Secundus [i.e., Pliny the Elder], “[Book XXV.] Of Pimpernell, Named Anagallis and Corchoros. […].”, in Philemon Holland, transl., The Historie of the World. Commonly Called, The Naturall Historie of C. Plinius Secundus. […], 2nd tome, London: […] Adam Islip, →OCLC, page 238:

Other things we feel hurt us, we forbear easily. An angry inflammation there is, the name of it is a noli mi tangere; and not that only, but any boil or sore endures not the touching. What? had Christ any sore place about Him, since His Passion? No; for St. Thomas put his finger, nay, his whole hand into the place of His wounds, and put Him to no pain at all. No place in Christ, for this noli me tangere neither.

1621 April 11 (Gregorian calendar), Lancelot Andrewes, “A Sermon Preached before the King’s Majesty at Whitehall, on the First of April, A.D. MDCXXI., Being Easter-Day”, in J[ohn] P[osthumous] W[ilson], editor, Ninety-six Sermons […], volume III, Oxford, Oxfordshire: John Henry Parker, published 1841, →OCLC, page 27:

This precious aunt of yours is become inſenſibly a part of my conſtitution—Damn her! She's a noli me tangere in my fleſh, vvhich I cannot bear to be touched or tampered with.

1771, [Tobias Smollett], “To Sir Watkin Phillips, of Jesus College, Oxon.”, in The Expedition of Humphry Clinker […], volume I, London: […] W. Johnston, […]; and B. Collins, […], →OCLC, page 126:

basal cell carcinoma
basal cell carcinoma

squamous cell carcinoma
squamous cell carcinoma

(medicine, obsolete) Any of various diseases causing ulcers of the skin and underlying tissues, especially of the face; many of these diseases are now thought to be due to basal cell carcinoma or squamous cell carcinoma.


endotherapy

en-noun

endotherapy (countable and uncountable, plural endotherapies)

Newer and Investigational Approaches to Antireflux Therapy Several new therapeutic approaches to antireflux treatment have been developed, including endotherapies that have been approved by the Food and Drug Administration, investigational endoscopic techniques to enhance the antireflux barrier, and investigational pharmacologic agents.

2004, Ronnie Fass, GERD/dyspepsia, →ISBN, page 278:

Although endotherapy was primarily used for the treatment of upper GI and peptic ulcer bleeding, these modalities have also been applied to patients with lower GI bleeding.

2008, Richard S. Irwin, James M. Rippe, Irwin and Rippe's Intensive Care Medicine, →ISBN, page 1175:

Furthermore, the available data regarding outcomes from minor papilla endotherapy are almost exclusively retrospective, involve small patient samples, varying definitions for pain outcomes, and have follow-up durations that are generally limited.

2010, Klaus Mönkemüller, C. Mel Wilcox, Miguel Muñoz-Navas, Interventional and Therapeutic Gastrointestinal Endoscopy, →ISBN, page 445:

(medicine) Any therapeutic procedure that involves the use of an endoscope to localize the intervention to a location inside the body.


onychocryptosis

From onycho- + Ancient Greek κρυπτός (kruptós, “I conceal”).


enterorrhexis

This paper reports 67 cases of enterorrhexis caused by closed abdominal injury, in which 11 cases are of duodenal rupture (16.42%), 48 of jejuno-ileuc rupture (71. 64%) and 8 of colonic rupture (11.94%).

1997 February, Li Li, Chen Shaoli, “Early Diagnosis and Treatment of Enterorrhexis Caused by Closed Abdominal Injury”, in Clinical Medicine of China:

Prenatal exposure of the neonate to cocaine can be associated with severe defects of gastro-intestinal tract, such as necrotizing enterocolitis (43-45) and enterorrhexis (46), which are due to vasoconstriction, because of the general hypoxia and ischaemia of the fetus.

2001 October 5, Anna Deltsidou, “Cocaine abuse in pregnancy”, in Epitheorese Klinikes Farmakologias Kai Farmakokinetikes, International Edition, volume 16:

To prevent colitis and enterorrhexis, it is important that we consider HSCR in patients with XLH and ACS for their early treatment such as in our 2 cases.

2008 May, Shigeru Nakakimura, Fumiaki Sasaki, Tadao Okada, Atsushiro Arisue, Kazutoshi Cho, Masami Yoshino, Yonehiro Kanemura, Mami Yamaski, Satoru Todo, “Hirschsprung's disease, acrocallosal syndrome, and congenital hydrocephalus: report of 2 patients and literature review”, in Journal of pediatric surgery, volume 43, number 5:

(medicine, rare) Rupture of the intestine.


transfusionist

(medicine) One who carries out a transfusion.


pentaquine

(pharmacology) Alternative form of pentaquin


keratiasis

(pathology) The presence of hard, horny tumors.


macitentan

From [Term?] + -entan (“endothelin receptor antagonist”).

af

Right and left ventricular collagen content was increased with pulmonary artery banding compared to sham-operated controls and ameliorated by macitentan.

2016 January 15, “Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload”, in PLOS ONE, →DOI:

(pharmacology) An endothelin receptor antagonist used to treat pulmonary arterial hypertension.


aesthesiogenic

en-adj

aesthesiogenic (comparative more aesthesiogenic, superlative most aesthesiogenic)

more aesthesiogenic (comparative)
most aesthesiogenic (superlative)

(medicine) Producing a sensation; stimulating the sense of touch.


anacusic

Only vibrotactile responses could be obtained in 59 ears in the presence of effusion, while only 8 ears in an effusion-free condition were classified as anacusic.

1997, Ted L. Tewfik, Vazken M. Der Kaloustian, Congenital Anomalies of the Ear, Nose, and Throat, page 99:

In the anacusic ear, eustachian tube obliteration, using muscle, bone, or foreign materials, may be indicated.

2003, Michael E. Glasscock, Aina J. Gulya, Glasscock-Shambaugh Surgery of the Ear, →ISBN, page 449:

Hearing loss may be conductive, sensorineural, or mixed, and the degree of loss may be mild, moderate, severe, profound, or total (anacusic).

2006, Meyer Michael Cohen, Perspectives on the Face, →ISBN, page 89:


faciobrachial

Seven patients (17.1%) presented with faciobrachial dystonic seizures (FBDS), and all patients had anti-LGI1 antibodies.

2016 January 16, “Effect of Immunotherapy on Seizure Outcome in Patients with Autoimmune Encephalitis: A Prospective Observational Registry Study”, in PLOS ONE, →DOI:


anapnea

From Greek αναπνέω (to breath). Note: an- is not a prefix here. It means air or wind.

Patients with anapnea-hypopnea index (AHI) of greater than ten events per hour were selected for this study.

1997, Kazuo Chin, Masashi Hirai, Takanobu Kuriyama, Motonari Fukui, Kenshi Kuno, Yanosuke Sagawa, Motoharu Ohi, “Changes in the arterial PCO₂ during a Single Night's Sleep in Patients with Obstructive Sleep Apnea.”, in Internal medicine, volume 36, number 7:

Arrest of anapnea or heartbeat happened in 2 cases.

2005 February, Xu Hong-zhen, Bai Lin, “Aspiration of gastric contents in pediatric anaesthesia: analysis of 49 cases”, in Chongqing Medical Journal:

The anapnea, circulation, cerebral state index (CSI) and the Observer Assessment of Alertness/Sedation(OAA/S) score were assessed in 60 patients with abdominal operation patients, who underwent propofol and remifentanil target controlled infusion (TCI).

2008 August, Zhang JingChen Yong-liangChao Ji-honget al., “Coadministration of propofol and remifentanil eliminates awareness during continuous epidural anesthesia in patients undergoing operation”, in Journal of Clinical and Experimental Medicine:

(medicine) Resumption of breathing after a period of halted respiration.


bradypeptic

bradypeptic (comparative more bradypeptic, superlative most bradypeptic)

more bradypeptic (comparative)
most bradypeptic (superlative)

(medicine, dated) Having abnormally slow digestion.


sanguinous

a sanguinous tumor


amygdalocortical

(anatomy) Relating to the amygdala and the cerebral cortex.


semiconservatively

(genetics) In a semiconservative fashion.


nanocormia

From nano- (“dwarf”) + Latin cormus, Ancient Greek κορμός (kormós, “trunk”).

Since a purified form of hCGH was first isolated from human pituitary in 1956 (Li and Papkoff, Science, 124, 1293 (1956)), there have been made a large number of works on hGH to elucidate, e.g., the effect of hCGH on human metabo lism (Beck, J. C. et al., Science, 125, 884(1957)) and inhibitory activity of hCGH on pituitary nanocormia (Raben, M. S., J. Clin. Endocrinol., 18,901(1958)).

2003, Se-Chang Kwon, Sung-youb Jung. Hoon Shin, Jay-Do Choi, Ki-Doo Choi, Gwan-Sun Lee, Modified E. coli enterotoxin II signal peptide and a microorganism expressing a fusion protein of a said peptide and a heterologous protein (US Patent US6605697B1):

For instance, if electric stimulus is given to the ventromedial hypothalamic lesion (VMH) in hypothalamus regions, it causes an increase of the amount of food intake, and causes a decrease of energy expenditure, thus resulting in obesity; if the lateral hypothalamus (LH) is stimulated by electricity, food intake decreases and energy expenditure increases, which causes nanocormia and anorexia

2011, D Han, S Kim, B Cho, “mRNA Expression on Neuropeptide Y (NPY) to Exercise Intensity and Recovery Time”, in Journal of Physical Therapy Science, volume 23, number 5:

(pathology) A form of dwarfism characterized by a very short trunk


hallical

(anatomy) Relating to the hallux, or big toe.


saroglitazar

/ˌsæɹ.əˈɡlɪt.əˌzɑɹ/

Probably from s(ulfanyl) + ar(yl) + -o- + -glitazar (“peroxisome proliferator activated receptors-α and -γ agonist”).

af

(pharmacology) A particular glitazar for the treatment of type 2 diabetes mellitus and dyslipidemia.


lizard brain

(anatomy, psychology) The most primitive part of the brain; the brain stem.


intratrabecular

Two main hypotheses aim to explain the mechanism of facilitation of the aqueous outflow by ALT: one hypothesis postulates that mechanical contraction of the trabecular meshwork by thermal energy opens the intratrabecular space, whereas the other one assumes that cellular activation of the trabecular meshwork causes remodeling of the extracellular matrix.

2016 January 26, “The Effect of Laser Trabeculoplasty on Posture-Induced Intraocular Pressure Changes in Patients with Open Angle Glaucoma”, in PLOS ONE, →DOI:


odontostyle

(anatomy) A protrusible, hollow, needle-like tooth found in nematodes, used to puncture and empty food items.


doxercalciferol

(pharmacology) A synthetic analogue of ergocalciferol, used as a drug to treat secondary hyperparathyroidism and metabolic bone disease.


nonculprit

(pathology) Of a lesion, etc.: not responsible for the diseased condition of the patient.


selisistat

From [Term?] + -stat (“enzyme inhibitor”).

In contrast, a SIRT1 inhibitor, selisistat, has been reported to alleviate HD-related phenotypes in multiple HD models and has been found to be safe in clinical trials.

2016 January 28, “SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington’s Disease Mice”, in PLOS ONE, →DOI:

(pharmacology) A particular SIRT1 inhibitor drug.


rectus femoris

en-noun

rectus femoris (plural recti femorum or recti femoris)

recti femorum (plural)
recti femoris (plural)

(anatomy) A fusiform muscle, one of the four quadriceps muscles, situated in the middle of the front of the thigh.


uncongressed

Analysing the presence of uncongressed chromosomes in metaphase cells showed a dose dependent increase in cells with congression defects following splitomicin and glipizide treatment […]

2015 October 10, “A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions”, in PLOS ONE, →DOI:


RSL

(medicine, statistics) Initialism of regional screening level.


microvasculitis

Although, atypical painless diabetic radiculoplexus neuropathies, with more symmetrical lower limb, and some with upper limb involvement, due to ischemic injury and microvasculitis, have also been described, these patients have axonal neuropathies and were excluded on clinical and electrophysiological criteria.

2015 October 14, “Treatment Responsiveness in CIDP Patients with Diabetes Is Associated with Higher Degrees of Demyelination”, in PLOS ONE, →DOI:


phosphoremia

A recent meta-analysis [15 ], aimed at assessing the association of ΔGFR with subsequent risk of ESRD, has similarly reported an association between improved eGFR and lower risk of ESRD. At variance with that study, however, we also considered proteinuria, causes of CKD, BMI, phosphoremia, uricemia and Hb, as potential confounders of CKD regression.

2015 October 14, “Epidemiology of CKD Regression in Patients under Nephrology Care”, in PLOS ONE, →DOI:

(pathology) The presence of phosphorus (typically as some form of phosphate) in the blood


solumedrol

The assessment included demographic characteristics (e.g., age, gender and education), medical information (e.g., diagnosis and type of surgery), and the evaluation of cognitive function using MMSE performed before the treatment of atropine and solumedrol.

2015 October 14, “Different MMSE Score Is Associated with Postoperative Delirium in Young-Old and Old-Old Adults”, in PLOS ONE, →DOI:

(medicine) An anti-inflammatory glucocorticoid containing a form of methylprednisolone


ulcerogenesis

This suggests that ZnPPIX counteracting protective effect of CORM-2 against ethanol ulcerogenesis cannot be explained by inhibitory effect of ZnPPIX on HO-1 enzyme expression and the mechanism of action of this compound in the stomach injured by ethanol should be further investigated.

2015 October 14, “Carbon Monoxide (CO) Released from Tricarbonyldichlororuthenium (II) Dimer (CORM-2) in Gastroprotection against Experimental Ethanol-Induced Gastric Damage”, in PLOS ONE, →DOI:


postmorbid

Finally, the Spanish version of the vocabulary subtest of the Wechsler Adult Intelligence Scale battery was administered to give an estimate IQ that was relatively resistant to postmorbid decline in the patients.

2016 February 2, “Counterfactual Reasoning Deficits in Schizophrenia Patients”, in PLOS ONE, →DOI:

(medicine) After the onset of morbidity.


extracytosolic

Albumin receptors megalin and cubilin both possess long extracytosolic domain floating in the urinary space.

2015 October 15, “Akt Links Insulin Signaling to Albumin Endocytosis in Proximal Tubule Epithelial Cells”, in PLOS ONE, →DOI:


nonexpresser

Recently, the receptors for SA were identified in Arabidopsis thaliana and named as nonexpresser of PR genes (NPR) 3 and 4 [5 ].

2015 October 15, “Plant Hormone Salicylic Acid Produced by a Malaria Parasite Controls Host Immunity and Cerebral Malaria Outcome”, in PLOS ONE, →DOI:

(genetics) Something that does not express genes


temporoorbital

After passing rostrally into the dorsotemporal fossa, the stapedial artery becomes the temporoorbital artery (temporal artery of Oelrich [52 ]).

2015 October 15, “Vascular Patterns in Iguanas and Other Squamates: Blood Vessels and Sites of Thermal Exchange”, in PLOS ONE, →DOI:

(anatomy) Relating to the temple and the orbit of the eye


emetize

en-verb

emetize (third-person singular simple present emetizes, present participle emetizing, simple past and past participle emetized)

emetizes (present singular third-person)
emetizing (participle present)
emetized (participle past)
emetized (past)

(transitive, medicine) To add an emetic into.


derangement syndrome

en-noun

derangement syndrome (plural derangement syndromes)

(pathology) One of three mechanical syndromes in the McKenzie method proposed in 1981 by the New Zealand physical therapist Robin McKenzie.


triciribine

From tricy(clic) + -ribine (“ribofuranosyl derivative of the pirazofurin type”).

af

(pharmacology) A cell-permeable tricyclic nucleoside used to treat cancer.


cabotegravir

From [Term?] + -tegravir (“HIV integrase inhibitor”).

(pharmacology) An integrase inhibitor used to treat HIV infection.


multipuncture

This study evaluated the utility of a new simulator system for multipuncture radiofrequency ablation.

2016 February 5, “Usefulness of a New Three-Dimensional Simulator System for Radiofrequency Ablation”, in PLOS ONE, →DOI:

(medicine) Involving more than one puncture.


hyperlinear

en-adj

hyperlinear (comparative more hyperlinear, superlative most hyperlinear)

more hyperlinear (comparative)
most hyperlinear (superlative)

Atopic patients with ichthyosis vulgaris often have keratosis pilaris and hyperlinear, exaggerated palm creases.

2015, Thomas P. Habif, Clinical Dermatology, →ISBN, page 165:

(dermatology) Having unusually pronounced creases marking the skin.


lichenization

en-noun

lichenization (usually uncountable, plural lichenizations)

(dermatology) Synonym of lichenification.


pyelo-

From Ancient Greek πύελος (púelos, “pelvis, wash basin”).

uder

(anatomy, medicine, surgery) Forms terms relating to the renal pelvis, such as pyelonephritis, pyelography, and others.


brallobarbital

(pharmacology) A barbiturate drug, now disused because of its disagreeable side effects.


HZ

en-noun

HZ (countable and uncountable, plural HZs)

(medicine, uncountable) Initialism of herpes zoster.


extracerebellar

/ˌɛkstɹəˌsɛɹəˈbɛlɚ/


rupintrivir

From [Term?] + [Term?] + -vir (“antiviral”).

(pharmacology) A particular synthetic protease inhibitor used as an antiviral drug.


ambulism

These, apart from nocturnal ambulism, are the simplest conditions of systematised partial waking.

1916, Carl Gustav Jung, Constance Ellen Long, Analytical Psychology:

(pathology) A disorder involving walking.


nonstimulant

A starch blocker is a nonstimulant, 100 per cent natural nutritional supplement derived from the white kidney bean.

2009 May 14, Malena Harbers, Toronto Star:

(pharmacology) Any substance that is not a stimulant.


hepatocarcinomatous

STC1 was found to be involved in inflammatory events [28, 29, 32 ] and was expressed in hepatocarcinomatous tissues [33, 34 ]; however, the role of STC1 in HCC progression is not known.

2015 October 16, “Stanniocalcin-1 Reduces Tumor Size in Human Hepatocellular Carcinoma”, in PLOS ONE, →DOI:

(oncology) Relating to carcinomas of the liver


hiatoplasty

LMAH, laparoscopic mesh augmented hiatoplasty; LH, laparoscopic hiatoplasty; OR, Odds Ratio; 95% CI, 95% confidence interval.

2015 October 16, “Use of Mesh in Laparoscopic Paraesophageal Hernia Repair: A Meta-Analysis and Risk-Benefit Analysis”, in PLOS ONE, →DOI:


hiatus hernia

(pathology) A protrusion of part of the upper stomach into the thorax


homopurine

In DNA homopyrimidine 2 homopurine triplexes [64 ], the homopyrimidine strands are antiparallel.

2015 October 16, “Polyanionic Carboxyethyl Peptide Nucleic Acids ( ce -PNAs): Synthesis and DNA Binding”, in PLOS ONE, →DOI:

(genetics) Describing a pairing of a purine with the same one on a neighboring strand of nucleic acid


homopyrimidine

In a recent paper on homopyrimidine decamers containing aeg-monomers and thymine monomers with a sulfomethyl substituent at the γ-position, similar triplexes has also been described [43 ].

(genetics) Describing a pairing of a pyrimidine with the same one on a neighboring strand of nucleic acid


homothymine

Additionally, this work presents the first synthesis of a homothymine polyanionic PNA α-oligomer ( 3 ).

(genetics) A homopyrimidine pairing in which the base is thymine


vermal

Faux Latin, from a supposed *vermalis, whereas Latin vermiculātus. From vermis + -al.


immunorepertoire

In present study, we investigated the diversity of the gamma 9/delta 2 T cell immunorepertoire and analysed the specificity of the expressed CDR3 in pulmonary tuberculosis patients.

2012, Tuberculosis—Advances in Research and Treatment: 2012 Edition:

(immunology) The sum of functionally diverse B and T cells in one's circulation at any given moment; the set of conditions that an immune system recongnizes.

Immunorepertoire analysis by multiplex PCR and 454 sequencing


pyelocaliceal

A recent Chinese study has also demonstrated that males and patients with pyelocaliceal tumors are at higher risk of advanced tumor stage than females and those with ureteral tumors, respectively [12 ].

2015 October 16, “Concurrent Preoperative Presence of Hydronephrosis and Flank Pain Independently Predicts Worse Outcome of Upper Tract Urothelial Carcinoma”, in PLOS ONE, →DOI:

(anatomy) Relating to the renal pelvis and the calices


exonal

Since the average gene has a mean of 8.8 exons each a mean of 145 base pairs (bp) long, the average gene has a mean exonal sequence length of ~1,300 bp [40 ].

2015 October 17, “Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA”, in PLOS ONE, →DOI:


hyperadiponectinemia

Accordingly, the findings of reverse association of BMI and ADPN and lower BMI among high ADPN group may partly explain reduced impact of hyperadiponectinemia on survival outcome in our study cohort.

2015 October 17, “Association of Adiponectin with High-Sensitivity C-Reactive Protein and Clinical Outcomes in Peritoneal Dialysis Patients: A 3.5-Year Follow-Up Study”, in PLOS ONE, →DOI:

(pathology) The presence of raised levels of adiponectin in the blood


hyperdivergent

The hyperdivergent facial morphology may play a role in the development of TMJOA. The stability of the TMJ disc depends on the integrity of the joint ligaments and the forces applied over the TMJ. Hyperdivergent facial morphology is prone to disc displacement because of the poor reciprocal fitting of the articular surfaces, that is, less contact area is observed between condylar head and glenoid fossa compared with hypodivergent facial morphology [27 ].

2015 October 17, “Cephalometric Analysis of the Facial Skeletal Morphology of Female Patients Exhibiting Skeletal Class II Deformity with and without Temporomandibular Joint Osteoarthrosis”, in PLOS ONE, →DOI:


intrasuprasellar

In regards to the postoperative CSF leakage, we reported an overall 6.9% rate, with 10% of cases occurring in extended approaches and 5.3% in standard approaches; all these lesions were intrasuprasellar cysts and all underwent a total removal.

2015 October 17, “Endoscopic Endonasal Approach in the Management of Rathke’s Cleft Cysts”, in PLOS ONE, →DOI:


nasomaxillary

The reduced condylar growth may enhance the development of N-Me from nasomaxillary complex growth and dentoalveolar development [25 ].

(anatomy) Relating to, or connecting, the nasal bone and the upper jaw


sphenoidotomy

As described elsewhere [28 –32, 40 ], the approach is realized through both nostrils with a middle turbinectomy on one side, resection of the posterior portion of the nasal septum and a wider anterior sphenoidotomy.

(surgery) The creation of an opening in the wall of the sphenoid sinus


undermedication

LL-Q1860 (eng)-Flame, not lame-undermedication.wav

In addition to the problem of overmedication, there is some evidence that undermedication also may be occurring, though its extent and causes are unknown.

1988, Helene L. Lipton, Philip Randolph Lee, Mark S. Freeland, Drugs and the Elderly: Clinical, Social, and Policy Perspectives:

(medicine) Insufficient medicating; underuse of medication.


mismedication

mismedication (countable and uncountable, plural mismedications)

There is ample documentation of overmedication, undermedication, and mismedication of nursing home residents.

2010, Professor Richard R Abood, Pharmacy Practice and the Law:

(medicine) Inappropriate use of medication, or use of a wrong medication.


demedication

This happens through a demedication and deconditioning process and being deeply felt by our facilitator.

2015, Wayne Vriend, Jillian Vriend, Christopher Tydeman, Living As If: Embrace Collapse, Heal Your Heart and Soul, and Find ...:

(medicine) Elimination or reduction of the use of a medication, or reduction of the level of a medication in the body.


angel dusting

(advertising, marketing, pharmacology) The misleading marketing practice of including a minuscule amount of an active ingredient in a product (such as food or cosmetics), insufficient to give any measurable benefit.


metathalamic

(anatomy) Of or pertaining to the metathalamus.


prostate-specific

en-adj

prostate-specific (comparative more prostate-specific, superlative most prostate-specific)

more prostate-specific (comparative)
most prostate-specific (superlative)

(health, physiology) Specific to the prostate.


gropability

(medicine, interface design) The state or condition of being gropable.


qcepo

(medicine, archaic) A skin disease of Peru, a form of leishmaniasis.


TRAP

twin reversed arterial perfusion
w:twin reversed arterial perfusion

(medicine) Initialism of twin reversed arterial perfusion.


GCM

giant cell myocarditis
giant cell myocarditis#English

(medicine) Initialism of giant cell myocarditis.


sacropelvic

(anatomy) Relating to the sacrum and pelvis.


osteophytosis

en-noun

osteophytosis (countable and uncountable, plural osteophytoses)


coronarography

(medicine) An X-ray of the coronary arteries


bordetellosis

bordetellosis (countable and uncountable, plural bordetelloses)

Mice with lethal bordetellosis indicated by ruffled fur, hunched stature, and limited responsiveness were euthanized to prevent unnecessary suffering.

2015 October 21, “Type Six Secretion System of Bordetella bronchiseptica and Adaptive Immune Components Limit Intracellular Survival During Infection”, in PLOS ONE, →DOI:

(pathology) An infection by bacteria of the genus Bordetella.


presupplementary

The optodes were positioned using a custom-made cap that covered the right and left PFC, presupplementary motor area (preSMA), supplementary motor area (SMA), dorsal premotor cortex (PMC), and sensorimotor cortex (SMC).

2015 October 21, “Changes in Cerebral Hemodynamics during Complex Motor Learning by Character Entry into Touch-Screen Terminals”, in PLOS ONE, →DOI:

(anatomy) In front of the supplementary motor area of the brain


homogenic

(genetics) (of a gamete or a population) Having only one allele of a gene or genes.


labyrinthopathy

(pathology) Any disease of the labyrinth of the ear


labyrinthosis

(pathology) inflammation of the labyrinth of the ear


cleithral

As none of the ovicells were observed to be closed by the operculum, presumably because they were empty and the opercula were resting on the primary orifice rim, the ovicell closure type is subcleithral rather than cleithral [51 ], at least in some species of the genus.

2015 October 22, “Diversity and Systematics of Schizomavella Species (Bryozoa: Bitectiporidae) from the Bathyal NE Atlantic”, in PLOS ONE, →DOI:

(anatomy) Relating to, or having, a cleithrum.


lenticulostriate

The adjacent region included the operculum, lenticulostriate nucleus, extreme capsule, and claustrum, whereas the remote region involved other areas within the MCA territory except for those assigned to the adjacent region.

2015 October 22, “Cardioembolism and Involvement of the Insular Cortex in Patients with Ischemic Stroke”, in PLOS ONE, →DOI:

(anatomy) Relating to the lentiform nucleus and the striatum

lenticuloestriado

relating to the lentiform nucleus and the striatum

lenticulostriate infarction

(anatomy) Relating to the lenticulostriate arteries (a group of small arteries arising at the commencement of the middle cerebral artery) or the territory supplied by those arteries.


meniscofemoral

On the other hand, the lateral meniscus is attached to the joint capsule by the meniscofemoral ligaments, popliteal tendon, popliteo-meniscal fascicle, and arcuate complex.

2015 October 22, “Comparison of Medial and Lateral Meniscus Root Tears”, in PLOS ONE, →DOI:

(anatomy) Relating to, or connecting a meniscus and a femur (of femoral condyle).


ventroposterior

The expression of Sema3A in the posterior and ventroposterior regions of the tectum has been postulated to channel RGC axons into the tectum [40 ], and ectopic application of FGF2 or heparin sulfates culminates in mistargeting of RGC axons [41 ,42 ].

2015 October 22, “NF-Protocadherin Regulates Retinal Ganglion Cell Axon Behaviour in the Developing Visual System”, in PLOS ONE, →DOI:


sonidegib

Among the inhibitors of the Hh pathway that interact directly with SMO, vismodegib and sonidegib are the two compounds approved by FDA in 2012 and 2015, respectively, for the treatment of basal cell carcinoma (BCC).

2016 March 3, “Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells”, in PLOS ONE, →DOI:

(pharmacology) A drug targeting the smoothened protein of the hedgehog signaling pathway, used for the treatment of basal cell carcinoma.


maribavir

From [Term?] + rib(osyl) + -a- + -vir (“antiviral”).

af

(pharmacology) An experimental antiviral drug for the prevention and treatment of human cytomegalovirus disease in transplant patients.


nontypeable

(medicine) Of a bacterium, lacking capsular serotypes.


hypercondensation

en-noun

hypercondensation (countable and uncountable, plural hypercondensations)

In addition, PNAP - 6h decreased CDK1 and cyclin B1 expression, most likely leading to G 2 /M arrest, and induced morphological changes, such as nuclear shrinkage, nuclear fragmentation, and nuclear hypercondensation, as observed by Hoechst 33342 staining.

2015 October 23, “Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells”, in PLOS ONE, →DOI:

(genetics) The severe compaction of chromosomes


lalopathy

From Ancient Greek λάλος (lálos) + -o- + -pathy.

Conversely a correct thought may be defectively expressed, but as soon as the formation of thoughts is disturbed it becomes a question of dyslogia and logopathy, or, as some would say, of logoneurosis, since every movement of thought takes place through the nerve-substance. The two ideas of logoneurosis and lalopathy consequently do not cover each other.

1877, Hugo Ziemssen, Albert Henry Buck, George Livingston Peabody, Cyclopædia of the Practice of Medicine - Volume 14, page 613:

Stammering. stuttering, apthongia, spasmodic hesitation. and “nervous speech” belong to the domain of lalopathy.

As for the symptom of brain metastasis, dyskinesia showed the highest incidence, being seen in 5 cases (56%), followed by headache, nausea, lalopathy, dysopia and aystaria.

1943, Géza Róheim, The origin and function of culture, page 231:

Myasthenoid syndrome (somnolence, hypotonia, ataxy, lalopathy) due to acute intentional poisoning with 0.250g of Diazepan was observed in a child.

1974, Psychopharmacology Abstracts, page 697:


laloplegia

From Ancient Greek λαλέω (laléō, “talk”) + -plegia.

af

He made expressive gestures to manifest his thoughts, and on giving him pencil and paper he was able to write them down. His tongue preserved all its movements and its sensibility. It was evidently a case of laloplegia.

1878 August 15, The Boston Medical and Surgical Journal, volume 99, page 220:

(pathology) paralysis of the organs of speech


hepatopathology

en-noun

hepatopathology (countable and uncountable, plural hepatopathologies)


monoclonated

Assays to detect antibody response to adult filarial antigen were performed using biotinylated monoclonated antibodies (Zymed Laboratories, San Francisco, CA) specific for IgG1, IgG2, IgG3, and IgG4.

2015 October 23, “Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti”, in PLOS ONE, →DOI:


dysomy

In humans, loss of imprinting or uniparental dysomy of imprinted genes contributes to diseases such as Prader-Willi, Angelman, and Beckwith-Wiedemann syndromes, all of which present cognitive dysfunctions.

2015 October 24, “Insulin Like Growth Factor 2 Expression in the Rat Brain Both in Basal Condition and following Learning Predominantly Derives from the Maternal Allele”, in PLOS ONE, →DOI:

(genetics) The inheritance of a pair of non-identical chromosomes


gametologue

Both types of sequence could potentially be exploited for the generation of sex markers because the male and female copies of gametologues are significantly different at the sequence level and markers designed from gametologue sequences have been successfully used to discriminate between sexes in different Ectocarpus species.

2015 October 24, “Development of PCR‐Based Markers to Determine the Sex of Kelps”, in PLOS ONE, →DOI:

(genetics) A gene that is homologous to one on a sex chromosome.


formicant

en-adj

formicant (comparative more formicant, superlative most formicant)

more formicant (comparative)
most formicant (superlative)

From Latin formica (“ant”); so called because supposed to resemble the motion of an ant.

(medicine, obsolete) Of the pulse: weak and rapid.


craniocerebellocardiac

(pathology) Affecting the cranium, cerebellum, and heart; applied to 3C syndrome.


coffin birth

(medicine, obstetrics) Postmortem fetal extrusion: the expulsion of a nonviable fetus through the vaginal opening of a deceased pregnant woman as a result of gaseous pressure through decomposition.


perfed

One would think that the wall of a human heart would have to be either perfed or not perfed.

2010, Dan Walter, Collateral Damage: A New Procedure, a Patient and the Learning Curve:


rhomboideum

(anatomy) The ligament that joins the sternal end of the clavicle with the cartilage of the first rib.


cor triatriatum

(pathology) Triatrial heart: a rare congenital heart defect where the left atrium (cor triatriatum sinistrum) or right atrium (cor triatriatum dextrum) is subdivided by a thin membrane, resulting in three atrial chambers.


dermatotoxic

dermatotoxic (comparative more dermatotoxic, superlative most dermatotoxic)

more dermatotoxic (comparative)
most dermatotoxic (superlative)


adhese

en-verb

adhese (third-person singular simple present adheses, present participle adhesing, simple past and past participle adhesed)

adheses (present singular third-person)
adhesing (participle present)
adhesed (participle past)
adhesed (past)

Apparently back-formation from adhesive or adhesion (itself related to adhere); compare Latin adhēsus.

Q. Freeing up the nerve relates to what? A. Freeing up the nerve would not mean that he would try to carefully dissect the nerve from anything that it may be attached to. Q. Adhesed to? A. Attached or adhesed to. Q. Okay. Why?

1977, Boyd v. City of Wyandotte, 402 MICH 98 (1977): Plaintiff-Appellant's Appendix on Appeal, page 353:

This maneuver preserves whatever rotator cuff might have been encased within the scar tissue that had become adhesed to the acromion. The shaver blade then completes the dissection of the lateral edge of this soft tissue envelope from[…]

2012 February 14, Paul C. Brady, Patrick J. Denard, The Cowboy's Companion: A Trail Guide for the Arthroscopic Shoulder Surgeon, Lippincott Williams & Wilkins, →ISBN, page 174:

Not frequently, the large intestine is also tightly adhesed to the ovary. Dissection is performed by gaining retroperitoneal entry to (1) free the intestine from the ovarian tissue, (2) free the ovary from the sidewall structures[…]

2020 October 1, Michael S. Baggish, Mickey M. Karram, Atlas of Pelvic Anatomy and Gynecologic Surgery E-Book, Elsevier Health Sciences, →ISBN, page 377:

(medicine) To unite via adhesion (abnormal union of surface).


expressor

(genetics) Alternative form of expresser


SVC

superior vena cava
superior vena cava#English

(anatomy) Initialism of superior vena cava.


-sal

(pharmacology) Used to form names of salicylic acid derivatives.


lues cerebri

Borrowed from Latin luēs (“syphilis”) + cerebrī (“of the brain”).


place cell

(neuroscience, anatomy) A type of pyramidal neuron within the hippocampus that becomes active when an animal enters a particular place in its environment (known as the place field).


Thermogene

Trade name, perhaps from thermo- + -gen.

(medicine, historical) A form of medicated wadding pinned inside the clothes to treat rheumatism, lumbago, etc.


labour pain

(obstetrics, gynaecology, British spelling, often plural) The pain suffered by a woman in labour during childbirth.


papillomacular

On the other hand, the correlation between sensitivity and mRNFLT was relatively low in the papillomacular bundle region within the central 5.8°, even after adjustment for RGC displacement.

2015 October 28, “Retinal Thickness and the Structure/Function Relationship in the Eyes of Older Adults with Glaucoma”, in PLOS ONE, →DOI:

(anatomy) Relating to the papilla and macula of the eye.


prenucleosomal

Since the three histone-fold domain amino acids are located at the surface of the α-helix 2 domain that is responsible for the formation of H3-H4 dimers and accessible in prenucleosomal complexes, it has been suggested that the specificity associated with these amino acid positions derives from interactions with different assembly or post-translational-modification machineries.

2015 October 28, “Comparing the Assembly and Handedness Dynamics of (H3.3-H4) 2 Tetrasomes to Canonical Tetrasomes”, in PLOS ONE, →DOI:

(genetics) Prior to the formation of nucleosomes; relating to prenucleosomes


antiturkey

(immunology) Describing an antibody that reacts with the immunoglobins found in turkeys.


reocclusion

en-noun

reocclusion (countable and uncountable, plural reocclusions)

(medicine) The recurrence of occlusion after it has been treated.


tetrasome

During chromatin assembly, the (H3-H4) 2 tetramer binds first, forming a tetrasome that likely constitutes an important intermediate during ongoing transcription.

(genetics) A complex of four homologous chromosomes formed during meiosis


thalamostriate

There were few veins of thalamus draining into TSV. Inthe transverse view, we also found small deep medullary veinswhich anastomose the tributaries of thalamostriate vein with the superficial medullary veins (Fig 4c and 4d ).

2015 October 28, “Susceptibility-Weighted Imaging of the Anatomic Variation of Thalamostriate Vein and Its Tributaries”, in PLOS ONE, →DOI:

(anatomy) Relating to, or connecting the corpus striatum and the thalamus.

talamoestriado

relating to the corpus striatum and the thalamus


ependymitis

ependymitis (countable and uncountable, plural ependymites)

However there were only 8 (4.8%) cases of subdural effusion and none of ependymitis or brain abscess in good outcome patients.

2015 October 29, “Clinical Prognosis in Neonatal Bacterial Meningitis: The Role of Cerebrospinal Fluid Protein”, in PLOS ONE, →DOI:

(pathology) inflammation of the ependyma


perithymic

In this context, we have previously shown the presence of LLMC in the perithymic adipose tissue and capsular region, as well as inside the thymic parenchyma, expressing the CCR5 chemokine receptor [18 ].

2015 October 29, “Lipid-Laden Multilocular Cells in the Aging Thymus Are Phenotypically Heterogeneous”, in PLOS ONE, →DOI:


thought blocking

thought blocking (usually uncountable, plural thought blockings)

/θɔːt ˈblɒkɪŋ/

/θɔːt ˈblɑkɪŋ/

(psychiatry) The phenomenon, in schizophrenia and other psychiatric disorders, where a person's speech is suddenly interrupted by silences.


autopeotomy

(medicine, rare) removal of one's own penis


myotilinopathy

(pathology) Any disease associated with the protein myotilin


DBD

(medicine) Initialism of donation after brain death. (of organ donation)


vulvoplasty

(surgery) A surgical procedure to construct, repair, or remodel a vulva.


semidominant

incomplete dominance
incomplete dominance

(genetics) Exhibiting incomplete dominance.


incomplete dominance

The snapdragon flower colour is either homozygous for red or white. When the red homozygous flower is paired with the white homozygous flower, the result yields a pink snapdragon flower; this is the result of incomplete dominance.

(genetics) The situation where the phenotype of the heterozygous phenotype is distinct from and often intermediate to the phenotypes of the homozygous phenotypes.


fenestrel

(pharmacology) A synthetic, non-steroidal estrogen developed as a postcoital contraceptive in the 1960s but was marketed.


orestrate

From [Term?] + -estr- (“estrogen”) + -ate.

(pharmacology) A synthetic steroidal estrogen, the 3-propanoyl, 17-(1-cyclohexenyl) ether of estradiol.


finerenone

From [Term?] + -renone (“spironolactone derivative”).

af

If the FDA expands the use of finerenone as a heart failure therapy, cardiologist Dr. Michelle Bloom said, she would think about it as an option for her patients with mildly reduced or preserved ejection fraction.

2024 January 9, Jacqueline Howard, “Kidney disease medication found to reduce risk of cardiovascular death in certain heart failure patients in new study”, in CNN:

(pharmacology) A non-steroidal antimineralocorticoid in trials for the treatment of chronic heart failure.


estrapronicate

From estra(diol) + pro(pionate) + -nicate (“antihypercholesterolemic or vasodilating nicotinic acid ester”).

(pharmacology) Estradiol 17-nicotinate 3-propionate, a synthetic steroidal estrogen.


nilestriol

(pharmacology) A synthetic steroidal estrogen, the 3-cyclopentyl ether of 17α-ethinyl estriol.


methestrol

(pharmacology) A synthetic non-steroidal estrogen of the stilbestrol group.


fosfestrol

From phosph(ate) + -estr- (“estrogen”) + -ol.

(pharmacology) Diethylstilbestrol diphosphate, a synthetic non-steroidal estrogen of the stilbestrol group, used in the treatment of prostate cancer.


cloxestradiol

From (tri)chlo(ro) + (hydr)ox(y) + estradiol.

(pharmacology) A synthetic steroidal estrogen, an analogue of estradiol with a 2,2,2-trichloroethoxy substitution.


hexestrol

(pharmacology) A synthetic non-steroidal estrogen of the stilbestrol group, formerly used to treat estrogen deficiency.


arzoxifene

From [Term?] + [Term?] + -oxifene (“tamoxifen derivative”).

(pharmacology) A particular selective estrogen receptor modulator.


droloxifene

From (hy)dro(xy)l + -oxifene (“tamoxifen derivative”).

(pharmacology) A particular antiestrogen.


thermopathology

(pathology) The branch of pathology that focuses on the effects of the temperature change.


dorsobasal

Furthermore, atelectasis in the dorsobasal and caudal areas of the lungs has been described because of limited pulmonary inflation and recruitment.

2016 February 6, “Mechanical Intestinal Obstruction in a Porcine Model: Effects of Intra-Abdominal Hypertension. A Preliminary Study”, in PLOS ONE, →DOI:


sacrovaginal

(anatomy) Relating to the sacrum and vagina.


pubourethral

(anatomy) Relating to the pubis and urethra.


pubovaginal

(anatomy) Relating to the pubis and vagina.


rolicyclidine

From (pyr)roli(dine) + cycl(ohexyl) + -clidine (“muscarinic receptor agonist/antagonist”).

(pharmacology) A dissociative anesthetic drug with hallucinogenic and sedative effects.


keloplasty

Often in keloplasty, prosthetic restorations are used to complement the surgical treatment.

1960 November-December, Edmund Pinto da Fonseca, “Stretching prosthesis for cicatricial deformities of the lips”, in The Journal of Prosthetic Dentistry, volume 10, number 6:

A comparison was also made with an already published study of 399 keloplasties with reinforcement of the peritoneal sac using the technique proposed by R. Stoppa.

1989, P Cubertafond, A Gainant, “[Treatment of inguinal hernia by Shouldice type herniorrhaphy. Analysis of a series of 403 cases surgically treated] (English abstract)”, in Chirurgie; memoires de l'Academie de Chirurgie, volume 115, number 2:

Keloplasty in the area of larynx and trachea is performed with the use of Ho-YAG laser, with shallow effect, regardless of the density of tissue, enabling coagulation of vascular vessels.

2003, Wiesław Woliński, Zdzisław Jankiewicz, Ryszard S. Romaniuk, Laser technology VII.: 23-27 September, 2002:

The patient was a 7-year-old boy (120 cm, 21 kg) who was scheduled to undergo keloplasty for resection of a nevus sebaceous of the right ear.

2010 August, B Kim, K Iwata, K Sugimoto, S Suzuki, Y Ema, H Tsunobuchi, K Nishiwaki, “Significance of prevention and early treatment of a postoperative twisted neck: atlantoaxial rotatory subluxation after head and neck surgery”, in Journal of Anesthesia, volume 34, number 4:

(medicine) The surgical removal of a scar or keloid.


petrosquamous

(anatomy) Relating to the petrous and squamous parts of the temporal bone.


petrotympanic

(anatomy) Relating to the petrous part of the temporal bone and to the tympanic cavity


squamotympanic

(anatomy) Relating to the squamous part of the temporal bone and to the tympanic cavity.


tympanic cavity

en-noun

tympanic cavity (plural tympanic cavities)

(anatomy) A small cavity surrounding the bones of the middle ear.


retrograde perfusion

(surgery) An artificial method of providing blood supply to an organ by delivering oxygenated blood through the veins.


retroperfusion

retrograde perfusion
retrograde perfusion#English

(surgery) Synonym of retrograde perfusion


kelosomia

(medicine, rare) A rare congenital malformation of the chest wall leading to protrusion of the abdominal or thoracic viscera; sternal cleft.


keratectasia

keratectasia (countable and uncountable, plural keratectasias)

We present a case of unilateral iatrogenic keratectasia developing 10 months after bilateral laser in situ keratomileusis (LASIK) involving enhancement surgery using a broad-beam excimer laser (Summit Apex) to treat 6.6 diopters (D) of myopia.

1999 April, Harry S Geggel, Audrey R Talley, “Delayed onset keratectasia following laser in situ keratomileusis”, in Journal of Cataract & Refractive Surgery, volume 25, number 4:

A clinical diagnosis of keratectasia can be suspected when a patient develops unstable vision associated with irregular astigmatism. It usually occurs 6 to 18 months after LASIK surgery, but it may occur at any time.

2006, Samir A. Melki, Dimitri T. Azar, 101 Pearls in Refractive, Cataract, and Corneal Surgery, →ISBN, page 66:

Increased negative keratometric diopters and oblate asphericity of the PCC are common after LASIK leading to mild keratectasia.

2006, Agarwals, Dr Agarwals' Textbook on Corneal Topography, →ISBN, page 130:

The minimum thickness of residual stroma to prevent ectasia should be 250 mm. However, some unknown factors can still be responsible for iatrogenic keratectasias.

2015, H. V. Nema, Nitin Nema, Recent Advances in Ophthalmology-12 - Volume 12, →ISBN, page 88:

(medicine) An abnormal bulging of the cornea due to thinning and scarring.


cystoprostatovesiculectomy

The patient with bladder cancer underwent bilateral pelvic lymphadenectomy and radical cystoprostatovesiculectomy with a continent catheterizable reservoir and final histology revealed pT3b pN0 (0/15) cM0 G3 mucus-producing adenocarcinoma of the bladder.

2015 October 30, “Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction?”, in PLOS ONE, →DOI:

(surgery) Removal of prostate and seminal vesicles using cystoscopy


prostatovesiculectomy

(surgery) Removal of prostate and seminal vesicles


mucusuria

Clinical symptoms reported by patients contain hematuria, dysuria, urgency and mucusuria as a sign of mucus production/secretion of these lesions [25, 28 ].

(pathology) The presence of mucus in the urine.


tibovirus

(pathology, virology) Any virus that is primarily transmitted by a tick.


robovirus

(pathology, virology) Any virus that is transmitted by an arthropod.


keratic

He also told me that he could see, on the cornea of my right eye, two keratic precipitates.

2005, Hugh Cook, Cancer Patient, →ISBN, page 50:

The patient then developed an allograft reaction; keratic deposits were present on the posterior surface of the graft, and the aqueous humour in the pocket between the membrane and the graft showed a positive ray with cells.

2009, CIBA Foundation Symposium, Corneal Graft Failure, →ISBN, page 11:

Oedema may be so extensive that the keratic precipitates are not appreciated.

2012, A.K. Gupta, Clinical Ophthalmology, →ISBN:

(ophthalmology) Arising from the cornea.

Above the stratum lucidum is the horny or keratic layer in which the cells, reduced to simple dried laminae, form a collection of strata.

1882, Victor Cornil, Louis Ranvier, Alice Marion Rowlands Hart, Manual of Pathological Histology, page 256:

Keratinization of cells gradually increased and keratic pearls formed.

1994, Dzhemal Sh. Beniashvili, Experimental Tumors in Monkeys, →ISBN, page 52:

The epidermal layer reacts to the production and adhesion of this keratic substance by descending along the artificial hair in a fashion that eventually encloses it.

2013, Masumi Inaba, Yoshitaka Inaba, Androgenetic Alopecia, →ISBN:

(medicine) rough and hard, especially as a result of keratinization.


disocclude

en-verb

disocclude (third-person singular simple present disoccludes, present participle disoccluding, simple past and past participle disoccluded)

disoccludes (present singular third-person)
disoccluding (participle present)
disoccluded (participle past)
disoccluded (past)

(transitive, dentistry, computer graphics) To cause to be no longer occluded.


postsinusoidal

Using this catheter, the pressure gradient from the intrahepatic site (lobar venous pressure) to the post-hepatic venous site reflects the vascular tone at the postsinusoidal hepatic venous 'sphincters'.

1996, Takashi Shimazu, Liver Innervation and the Neural Control of Hepatic Function, page 242:

For estimation of volumetric blood flow, red blood cell (RBC) velocity and the respective vessel diameters were measured within 7–10 individual sinusoids and 5 postsinusoidal venules per animal [7 ].

2015 November 3, “Portal Hyperperfusion after Extended Hepatectomy Does Not Induce a Hepatic Arterial Buffer Response (HABR) but Impairs Mitochondrial Redox State and Hepatocellular Oxygenation”, in PLOS ONE, →DOI:


toxidermia

en-noun

toxidermia (countable and uncountable, plural toxidermias)

Subjects with peripheral hypereosinophilia defined as in [13 ] related to other diseases were also recruited, including subjects with dermatologic disease (n = 3, i.e prurigo, bullous pemphigoid and drug toxidermia), parasitosis (n = 3, i.e giardiasis, ascaridiosis and scabies) and pulmonary aspergillosis (n = 5, with 2 of them also suffering from asthma associated to bronchopulmonary aspergillosis.)

2015 November 3, “Circulating Human Eosinophils Share a Similar Transcriptional Profile in Asthma and Other Hypereosinophilic Disorders”, in PLOS ONE, →DOI:

(pathology) The presence of skin lesions as a result of the action of toxins or allergens


keratorefractive

For example, it has mostly been used in assessing optical quality as well as intraocular scattering changes in different kinds of refractive surgeries, such as after phakic intraocular lens implantation,[8 –9 ] and keratorefractive surgeries, including PRK, LASIK and femto-second laser small incision lenticule extraction (SMILE).

2015 November 5, “Intra- and Intersession Repeatability of an Optical Quality and Intraocular Scattering Measurement System in Children”, in PLOS ONE, →DOI:

(surgery) Involving modification of the shape of the cornea in order to reduce refractive error


meningoencephalomyelitis

(pathology) A form of encephalomyelitis that also affects the meninges


mithralog

A promising mithralog with improved therapeutic window, named DIG-MSK (demycarosyl-3D-ß-D-digitoxosyl-mithramycin SK; EC-8042) has been reported (Fig 1 ).

2015 November 5, “Pleiotropic Anti-Angiogenic and Anti-Oncogenic Activities of the Novel Mithralog Demycarosyl-3D-ß-D-Digitoxosyl-Mithramycin SK (EC-8042)”, in PLOS ONE, →DOI:


seroincidence

Annual HIV seroincidence and 95% confidence intervals (CIs) were calculated using the 155-day window period and the standard seroincidence formula as described elsewhere [20 ].

2015 November 5, “Assessing the HIV-1 Epidemic in Brazilian Drug Users: A Molecular Epidemiology Approach”, in PLOS ONE, →DOI:

(pathology) The incidence of a particular material in blood serum (typically HIV)


keratotorus

In contrast to keratoconus, which can be regarded as an irregular deformity, there is keratotorus in which there is regular increase in curvature over a limited area of the cornea.

1972, Arnold Sorsby, Modern ophthalmology: Topical aspects, →ISBN, page 246:

The effect of such a peripheral ectasia may be the development of irregular astigmatism, although in this case it would result from keratotorus which is an inverse form of keratoconus.

1980, Ronald A. Schachar, Norman S. Levy, Les Schachar, Radial Keratotomy, page 159:

There is some consensus that keratoconus, keratotorus, keratoglobus, and pellucid zone degeneration are related because these different conditions have been found to coexist in families.

2000, Daniel M. Albert, Frederick A. Jakobiec, Principles and Practice of Ophthalmology, →ISBN, page 735:

(ophthalmology) A corneal herniation accompanied by severe regular myopic astigmatism.