sofosbuvir

From [Term?] + -fos- (“phosphorous derivative”) + -buvir (“RNA polymerase (NS5B) inhibitor”).

Sofosbuvir does not affect cyclosporine or tacrolimus concentrations.

2013, Marina Berenguer, Hepatitis C Virus and Liver Transplantation, →ISBN, page 57:

In the US, sofosbuvir and simeprevir have been approved for the treatment of chronic hepatitis C.

2015, Nicholas J Talley, Essentials of Internal Medicine 3e, →ISBN, page 382:

(pharmacology) A nucleotide analog used in combination with other drugs for the treatment of hepatitis C.


gevokizumab

From [Term?] + -ki- (“interleukin”) + -zumab (“humanized monoclonal antibody”).

af

(pharmacology) A particular monoclonal antibody.


ulipristal

From uli- (of unknown origin) + (mife)prist(one) + a(cety)l.

(pharmacology) A selective progesterone receptor modulator used in the acetate form for emergency contraception and to treat uterine fibroids.


fondaparinux

From fonda- (of unknown origin) + -parinux (“synthetic heparinoid”).

Moreover, we provide here additional positive experience in the treatment of both, CVT and HIT, by fondaparinux with bridging to warfarin given their successful evolution under this anticoagulant option.

2013 July 9, J Hsieh et al., “Cerebral venous thrombosis due to cryptogenic organising pneumopathy with antiphospholipid syndrome worsened by heparin-induced thrombocytopenia”, in BMJ Case Reports, volume 2013, →DOI:

(pharmacology) An anticoagulant medication chemically related to low-molecular-weight heparins.


glinide

(organic chemistry, pharmacology) Contraction of meglitinide.


antilipolytic

en-adj

antilipolytic (comparative more antilipolytic, superlative most antilipolytic)

more antilipolytic (comparative)
most antilipolytic (superlative)

GPR81 is expressed primarily in adipocytes and have^([sic]) an antilipolytic effect (Liu et al., 2009).

2015 June 19, Graciela L. Garrote, Analía G. Abraham, Martín Rumbo, “Is lactate an undervalued functional component of fermented food products?”, in Frontiers in Microbiology, volume 6, →DOI:


parecoxib

All patients also received 1 g IV paracetamol, 1.5 mg/kg IV tramadol and 40 mg IV parecoxib analgesia intraoperatively, as well as pre-emptive antiemesis of 8 mg IV dexamethasone and 1 mg IV granisetron.

2015 July 2, Chong Oon Tan et al., “Surgical predictors of acute postoperative pain after hip arthroscopy”, in BMC Anesthesiology, volume 15, →DOI:

(pharmacology) A water-soluble and injectable prodrug of valdecoxib.


ertapenem

(organic chemistry, pharmacology) A particular carbapenem antibiotic, structurally similar to meropenem.


antianabolic

(pharmacology) That inhibit anabolic functions (such as tissue formation)


antiestrogenic

Tamoxifen, a nonsteroidal antiestrogenic agent, is used widely as adjunctive therapy for women with breast cancer.

2015, Alka Jindal et al., “Endometrial evaluation by ultrasonography, hysteroscopy and histopathology in cases of breast carcinoma on Tamoxifen therapy”, in Journal of Mid-Life Health, volume 6, →DOI:


anticytotoxic

Another option exists for eliminating Tregs is anticytotoxic T-lymphocyte antigen 4 (CTLA4) antibodies.

2015 June 17, Liu Yang et al., “Dendritic Cell-Based Immunotherapy Treatment for Glioblastoma Multiforme”, in BioMed Research International, volume 2015, →DOI:

(toxicology, pharmacology) Acting against cytotoxic effects.


ganitumab

From -tu- (“tumor”) + -umab (“human monoclonal antibody”).

af

While a randomized Phase II study testing the addition of the IGF1R mab ganitumab to chemotherapy in EWS is ongoing (NCT02306161), CAR T cells targeting IGF1R may be an alternative treatment for high risk patients with EWS and other sarcomas.

2015 July 15, “IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas”, in PLOS ONE, →DOI:

(pharmacology) A human monoclonal antibody against type 1 insulin-like growth factor receptor, designed for the treatment of cancers.


enzalutamide

From (b)enza(mide) + -lutamide (“nonsteroid antiandrogen”).

Abiraterone and enzalutamide are newly approved drugs for CRPC patients; although, patients will still eventually relapse and the overall survival is prolonged only ~4–5 months after treatment with the AR signaling becoming active in most of these relapsed tumors.

2015 July 16, “Poly (A) Binding Protein Cytoplasmic 1 Is a Novel Co-Regulator of the Androgen Receptor”, in PLOS ONE, →DOI:

(pharmacology) A synthetic, non-steroidal pure antiandrogen developed for the treatment of metastatic castration-resistant prostate cancer.


ledipasvir

From [Term?] + -asvir (“hepatitis C virus NS5A inhibitor”).

(pharmacology) A particular drug for the treatment of hepatitis C.


aducanumab

From -n- (“neural”) + -umab (“human monoclonal antibody”).

Biogen’s drug, aducanumab, slowed the decline in cognition in an early-stage trial.

2015 July 19, The New York Times, “Greece’s Debt Payments, Apple Earnings and Credit Suisse Results”, in New York Times:

(pharmacology) A human monoclonal antibody and drug candidate designed for treatment of Alzheimer's disease.


antilipemic

en-adj

antilipemic (comparative more antilipemic, superlative most antilipemic)

more antilipemic (comparative)
most antilipemic (superlative)

Conversely, peak blood concentration is comparable to the highest evaluated affinity for the antibacterial norfloxacin, and higher than this threshold for the three antilipemic medications pravastatin, fluvastatin and atorvastatin.

2015 July 14, “All-Purpose Containers? Lipid-Binding Protein – Drug Interactions”, in PLOS ONE, →DOI:

(pharmacology) That lowers the amount of lipid in the blood

antilipemico

that lowers the amount of lipid in the blood


obinutuzumab

From [Term?] + -tu- (“tumor”) + -zumab (“humanized monoclonal antibody”).

af

Recently, mogamulizumab (anti-CCR4 antibody, Kyowa Hakko Kirin) and obinutuzumab (anti-CD20 antibody, Genentech/Roche) with depleted core fucoses have been approved for marketing, and several glycoengineered antibodies are in clinical studies and are being developed as next generation therapeutic monoclonal antibodies.

2015 July 23, “Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities”, in PLOS ONE, →DOI:


nivolumab

From -l- (“immunomodulating”) + -umab (“human monoclonal antibody”).

checkpoint inhibitor
checkpoint inhibitor

(pharmacology) a human IgG4 anti-PD-1 monoclonal antibody, acting as a checkpoint inhibitor, thus allowing activated T cells to attack cancer cells


paritaprevir

From [Term?] + -previr (“hepatitis C virus protease inhibitor”).

(pharmacology) An acylsulfonamide inhibitor of the NS3-4A serine protease, under investigation for the treatment of hepatitis C.


mometasone

From [Term?] + -metasone (“prednisone or prednisolone derivative”).

The ICS formulations reported in the trials included beclometasone, budesonide, ciclesonide, flunisolide, fluticasone, and mometasone.

2015 July 21, “Impact of Inhaled Corticosteroids on Growth in Children with Asthma: Systematic Review and Meta-Analysis”, in PLOS ONE, →DOI:

(pharmacology) A glucocorticosteroid drug used topically in the furoate form to reduce inflammation.


zibotentan

From [Term?] + -entan (“endothelin receptor antagonist”).

The indirect comparisons showed that there were no significant differences between zibotentan plus docetaxel versus atrasentan plus docetaxel when compared with docetaxel alone or zibotentan versus atrasenta compared with placebo in the improvement of PFS, OS, TTP, and total adverse events.

2015 July 21, “A Meta-Analysis and Indirect Comparison of Endothelin A Receptor Antagonist for Castration-Resistant Prostate Cancer”, in PLOS ONE, →DOI:

(pharmacology) An endothelin receptor antagonist under investigation as an anticancer drug.


ombitasvir

(pharmacology) A particular antiviral drug for the treatment of hepatitis C virus.


methylthioninium

From methyl + thionine + -ium (“quaternary ammonium compound”).

Methylene blue (MB, methylthioninium chloride) is a phenothiazine that crosses the blood brain barrier and acts as a redox cycler.

2014 February 20, Cliona Stack et al., “Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity”, in Human Molecular Genetics, volume 23, →DOI:

(organic chemistry, pharmacology) The heterocyclic cation 3,7-bis(dimethylamino)-phenothiazin-5-ium, which is the basis of methylene blue


antiglaucomatous

Noteworthy, the ocular hypotensive effect promoted by D+I did not interfere in the MAP. This characteristic is desirable for any antiglaucomatous drug or formulation as it increases its specificity reducing potential side effects.

2015 July 24, “Ocular Inserts for Sustained Release of the Angiotensin-Converting Enzyme 2 Activator, Diminazene Aceturate, to Treat Glaucoma in Rats”, in PLOS ONE, →DOI:


antichlamydial

Although we cannot exclude that inter-clone recombination may have also contributed to this notable frequency increase, values of this magnitude were only previously observed under strong selective pressures with antichlamydial compounds [137 ].

2015 July 25, “Chlamydia trachomatis In Vivo to In Vitro Transition Reveals Mechanisms of Phase Variation and Down-Regulation of Virulence Factors”, in PLOS ONE, →DOI:

(pharmacology) Acting against chlamydia.


TUE

therapeutic use exemption
therapeutic use exemption#English

(sports pharmacology) Initialism of therapeutic use exemption.


therapeutic use exemption

en-noun

therapeutic use exemption (plural therapeutic use exemptions)

(sports pharmacology) An exemption which allows the use of a banned substance for therapeutic purposes so that a ban from competition will not result when testing yields a positive results.


evolocumab

From [Term?] + -c- (“cardiovascular”) + -umab (“human monoclonal antibody”).

af

So was Repatha, or evolocumab, a similar drug developed by Amgen that is expected to win F.D.A. approval by the end of August.

2015 July 24, Andrew Pollack, “New Drug Sharply Lowers Cholesterol, but It’s Costly”, in New York Times:

(pharmacology) A human monoclonal antibody designed for the treatment of hyperlipidemia.


alirocumab

/ˌæl.ɪˈɹɑk.jəˌmæb/

Praluent, also known as alirocumab, was endorsed last month by outside advisers to the Food and Drug Administration .

(pharmacology) A human monoclonal antibody used to treat high cholesterol.


rilpivirine

From [Term?] + -virine (“nonnucleoside reverse transcriptase inhibitor”).

In this paper, we excluded the HIV infected patients taking indinavir, didanosine or rilpivirine as the initial regimen for cART.

2015 July 25, “Reasons and Risk Factors for the Initial Regimen Modification in Chinese Treatment-Naïve Patients with HIV Infection: A Retrospective Cohort Analysis”, in PLOS ONE, →DOI:

(pharmacology) A drug used to treat HIV infection.


galeterone

From [Term?] + -terone (“antiandrogen”).

(pharmacology) A steroidal antiandrogen under development for the treatment of prostate cancer.


etoricoxib

From etori- (of unknown origin) + -coxib (“cyclo-oxygenase inhibitor”).

A selective COX-2 inhibitor, etoricoxib, was reported to reduce the expression of NF-κB protein and inhibit DMH-induced colon ACF in rats.

2015 July 14, Li Zhang, Handong Wang, Orazio Taglialatela-Scafati, “Multiple Mechanisms of Anti-Cancer Effects Exerted by Astaxanthin”, in Marine Drugs, volume 13, →DOI:

nonsteroidal anti-inflammatory drug
nonsteroidal anti-inflammatory drug

(pharmacology) A synthetic, nonsteroidal anti-inflammatory drug with antipyretic, analgesic, and potential antineoplastic properties.


ruxolitinib

For example, Gallipoli et al. reported that combination of nilotinib with ruxolitinib could induce apoptosis in chronic myeloid leukemia (CML) stem cells through inhibiting JAK-2/STAT-5 signaling pathway.

The first jakinib to enter clinical trials, initially for renal transplantation, was tofacitinib, which inhibits JAK1/JAK2/JAK3; however, ruxolitinib, a JAK1/JAK2 inhibitor, was the first agent to receive approval, as a treatment for myeloproliferative neoplasms that often exhibit gain-of-function JAK2 mutations.

2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2168:

(pharmacology) A medication belonging to the class of Janus kinase inhibitors, used for the treatment of several diseases including myelofibrosis and polycythemia vera.


vintafolide

From vin- (“vinca alkaloid”) + [Term?] + folyl + -ide.

(pharmacology) A drug, being investigated as a cancer treatment, that combines vinblastine with a small molecule targeting the folate receptor.


mofetil

With respect to the cytotoxic effects, compounds 2–7 fall into two groups: the alkyl esters ( 2, 3 ) and the mofetil ester 4 on one hand, and the basic heterocyclic esters 5–7 on the other hand.

2015 July 22, “Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells”, in PLOS ONE, →DOI:

(pharmacology) Contraction of morpholinoethyl.


antidysentery

(pharmacology) Working against dysentery.


quant suff

Borrowed from Latin quantum sufficit (“as much as is required”), then clipped to only the first syllable of each word.

bor

(pharmacology, dated) The amount of the last ingredient in a recipe or prescription required to make it up to the required quantity of a mixture.


daclatasvir

In contrast, the HIV-1 protease inhibitor nelfinavir or the HCV NS5A inhibitor daclatasvir only blocks the replication of a single virus in the “co-infection” system.

2015 August 12, “The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action”, in PLOS ONE, →DOI:

(pharmacology) A drug for the treatment of hepatitis C.


elbasvir

(pharmacology) An experimental drug for the treatment of hepatitis C.


grazoprevir

A phase-II multicenter study has assessed the efficacy and safety of the combination of grazoprevir (MK-5172) and elbasvir (MK-8742) given to patients with chronic hepatitis and chronic kidney disease, including hemodialysis patients […]

2015 July 16, Mireille Mehawej et al., “Boceprevir-Based Triple Antiviral Therapy for Chronic Hepatitis C Virus Infection in Kidney-Transplant Candidates”, in Journal of Transplantation, volume 2015, →DOI:


aclidinium

From [Term?] + -clidinium (“muscarinic receptor agonist/antagonist”).

af

(pharmacology) A particular muscarinic antagonist, administered in the bromide form.


indacaterol

From ind(enyl) + ca(rbostyril) + -terol (“phenethylamine derivative”).

chronic obstructive pulmonary disease
chronic obstructive pulmonary disease

(pharmacology) An ultra-long-acting beta-adrenoceptor agonist used in the treatment of chronic obstructive pulmonary disease.


oclacitinib

Delgocitinib (JTE-052) is a topical jakinib approved in Japan for atopic dermatitis and oclacitinib, a JAK1/JAK2/JAK3 inhibitor, is approved for canine allergic dermatitis.

2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2170:

(pharmacology) A veterinary medication belonging to the class of Janus kinase inhibitors, used for the treatment of atopic dermatitis in dogs.


chloral hydrate

/ˌklɔɹˌæl ˈhaɪˌdɹeɪt/

(organic chemistry, pharmacology) An organic compound with the chemical formula C₂H₃Cl₃O₂, used as a sedative and hypnotic drug and as a laboratory reagent and precursor.


pyrrolobenzodiazepine

From pyrrol + -o- + benzo- + di- + azepine.

SG2000 (SJG-136, NSC694501) is a rationally designed pyrrolobenzodiazepine dimer which interacts sequence selectively in the minor groove of DNA.

2015 August 19, Maria Mellinas-Gomez et al., “Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours”, in BMC Veterinary Research, volume 11, →DOI:

(pharmacology) A class of compounds with antibiotic and anti-tumor properties.


prontosil

In the field of therapeutic aids, chemotherapy and antibiotics have been completely developed since that time. We had prontosil and neoprontosil and thought we were very fortunate.

1951 July, Richard D. Reekie, “Critical Analysis of Recent Advances in Gynecology”, in Northwest Medicine, volume 50, number 7, Portland, Ore.: Northwest Medical Publishing Association, page 508:

Since 1935 when Domagk demonstrated that prontosil provided effective therapy in a murine pneumococcal infection model, the use of animal infection models has become an integral part of the evaluation of new antimicrobial agents and new therapeutic approaches for clinical trials in humans.

2015 July 25, Mengxiao Gu et al., “Response of a clinical Escherichia coli strain to repeated cefquinome exposure in a piglet tissue-cage model”, in BMC Veterinary Research, volume 11, →DOI:

(pharmacology) The antibacterial drug 4-[(2,4-diaminophenyl)azo]benzenesulfonamide.


counteradaptation

en-noun

counteradaptation (countable and uncountable, plural counteradaptations)

counteradaptations (plural)
counter-adaptation (alternative)

Repeated AOD exposure also can lead to adaptations in the reward circuitry that oppose and neutralize a drug's effects (i.e., counteradaptation).

1997, Alcohol Health and Research World- Volume 21:

Counteradaptation postulates that the initial positive rewarding feelings are followed by the opposing development of tolerance.

2010, Marie A. Chisholm-Burns, Terry L. Schwinghammer, Barbara G. Wells, Pharmacotherapy Principles and Practice, page 610:

The conceptual framework of opponent process counteradaptation involves an initial a-process (positive hedonic effect; "light side") occurring shortly after presentation of the reinforcer followed by a b-process (negative hedonic effect; "dark side") appearing after the a-process has terminated.

2011, William R. Miller, Kathleen M. Carroll, Rethinking Substance Abuse:

Sensitization and counteradaptation are two of the major neuroadaptive models that have been proposed to explain how changes that start in the reward pathway may result in the development of substance dependence.

2013, John E. Niederhuber, James O. Armitage, James H Doroshow, Abeloff's Clinical Oncology, page 363:

adaptation that counters a change to an organism's environment

(pharmacology) The development of tolerance; the adaptation of the body's homeostatic mechanisms to counteract a drug effect.


umeclidinium

(pharmacology) An anticholinergic drug used in the bromide form, in combination with vilanterol, for the treatment of chronic obstructive pulmonary disease.


vilanterol

From [Term?] + -terol (“phenethylamine derivative”).

af

(pharmacology) A long-acting beta-2 agonist drug, used in the treatment of chronic obstructive pulmonary disease.


-olol

From propranolol. By surface analysis, reduplication of -ol.

β-adrenoceptor
w:adrenergic receptors#β receptors

(pharmacology) Used to form names of compounds with the structure Ar–OCH₂CH(OH)CH₂NH–R used as β-adrenoceptor antagonists.


betrixaban

From [Term?] + -xaban (“blood coagulation factor Xa inhibitor”).

The problem of renal excretion, and so, inadvisability in the face of low creatinine clearance, may be addressed by betrixaban, little of which is excreted via this organ.

2015 August 20, Andrew Blann, “Nonvitamin K antagonist oral anticoagulants (NOACs): the tide continues to come in”, in Vascular Health and Risk Management, volume 11, →DOI:

(pharmacology) A particular anticoagulant drug.


darexaban

(pharmacology) An experimental drug that acts as an anticoagulant and antithrombotic.


fostamatinib

From fos- (“phosphorous derivative”) + [Term?] + -tinib (“tyrosine kinase inhibitor”).

(pharmacology) A particular drug that is an inhibitor of the enzyme spleen tyrosine kinase (Syk).


dasabuvir

From [Term?] + -buvir (“RNA polymerase (NS5B) inhibitor”).

(pharmacology) An antiviral drug for the treatment of hepatitis C virus infection.


miravirsen

From [Term?] + -virsen (“antiviral antisense oligonucleotide”).

Currently, miravirsen is applied in seven clinical trials, some are already in phase II.

2015 August 13, Merav Kedmi et al., “MicroRNAs and Growth Factors: An Alliance Propelling Tumor Progression”, in Journal of Clinical Medicine, volume 4, →DOI:

(pharmacology) A locked nucleic acid-based antisense oligonucleotide with potential medical applications.


empagliflozin

From empa- (of unknown origin) + -gliflozin (“sodium–glucose cotransporter inhibitor”).

(pharmacology) An orally available competitive inhibitor of sodium–glucose co-transporter 2 (SGLT2; SLC5A2) with antihyperglycemic activity.


gliflozin

(pharmacology) Any of a class of drugs that inhibit renal glucose reabsorption and therefore lower blood glucose.


ertugliflozin

From [Term?] + -gliflozin (“phlorizin derivative”).

(pharmacology) A particular gliflozin drug.


remogliflozin

remogliflozin etabonate
remogliflozin etabonate#English

(pharmacology) Synonym of remogliflozin etabonate.


fenpiverinium

From (di)phen(yl) + pi(peridine) + -verine (“spasmolytic”) + -ium (“quaternary ammonium compound”).

(pharmacology) A particular antimuscarinic drug.


imepitoin

From im(idazolone) + [Term?] + -toin (“hydantoin derivative”).

(pharmacology) A particular antiepileptic drug.


migalastat

From [Term?] + -stat (“enzyme inhibitor”).

Based on preclinical data, migalastat HCl in combination with agalsidase is expected to result in the pharmacokinetic (PK) enhancement of agalsidase in plasma by increasing the systemic exposure of active agalsidase, thereby leading to increased cellular levels in disease-relevant tissues.

2015 August 8, “Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase”, in PLOS ONE, →DOI:

(pharmacology) A drug used to treat Fabry disease


faldaprevir

From [Term?] + -previr (“hepatitis C virus protease inhibitor”).

In similar pharmacokinetic studies in healthy volunteers, faldaprevir concentrations were increased by ritonavir-boosted darunavir, and decreased by tenofovir and efavirenz, which may ultimately require dose adjustments of the HCV PI in the presence of certain ARVs.

2013 December 15, Tilahun Amdissa Gemtessa, Lisa M. Chirch, “Update on Hepatitis C Virus and HIV Coinfection”, in Journal of Clinical and Translational Hepatology, volume 1, →DOI:

(pharmacology) An experimental drug for the treatment of hepatitis C.


ospemifene

From [Term?] + [Term?] + -mifene (“clomifene derivative”).

While raloxifene and tamoxifen have no estrogen agonist effect on the vagina, lasofoxifene and ospemifene show a positive impact on vaginal tissue in postmenopausal women.

2015 August 28, Hyun-Kyung Kim et al., “The Recent Review of the Genitourinary Syndrome of Menopause”, in Journal of Menopausal Medicine, volume 21, →DOI:

(pharmacology) An oral medication used to treat dyspareunia.


ripasudil

Some selective ROCK inhibitors are actually used in clinical practice, for example, fasudil and ripasudil are therapeutic agents for cerebral vasospasm and glaucoma, respectively.

2015 September 15, “Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study”, in PLOS ONE, →DOI:

(pharmacology) A drug derived from fasudil and used to treat glaucoma and ocular hypertension.


sitamaquine

Apart from amphotericin B and sitamaquine that can be considered as control drugs in this screening, clofazimine was the only compound exhibiting activity in the Leishmania donovani intracellular assay as well as an acceptable level of selectivity (SI ~10) (Table 3, S4 Fig ).

2015 August 14, “Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning”, in PLOS ONE, →DOI:

(pharmacology) A particular aminoquinoline that may be an antileishmanial drug


mogamulizumab

From [Term?] + -li- (“immunomodulating”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A humanized monoclonal antibody used to treat adult T-cell leukemia/lymphoma.


onartuzumab

From [Term?] + -tu- (“tumor”) + -zumab (“humanized monoclonal antibody”).

This publication describes the safety profile of onartuzumab in patients with solid tumors using data from the global onartuzumab clinical development program.

2015 October 8, “Safety of Onartuzumab in Patients with Solid Tumors: Experience to Date from the Onartuzumab Clinical Trial Program”, in PLOS ONE, →DOI:

(pharmacology) A humanized monoclonal antibody designed to treat cancer.


iodopovidone

After cleaning the surgical areas with iodopovidone, the swine were then instrumented with a right internal jugular pulmonary artery catheter through an 8 French introducer, a right femoral vein 10 French introducer and a right femoral artery triple lumen catheter.

2015 September 15, “Inhaled Carbon Monoxide Protects against the Development of Shock and Mitochondrial Injury following Hemorrhage and Resuscitation”, in PLOS ONE, →DOI:

(pharmacology) Synonym of povidone-iodine.


ferroquine

(pharmacology) A particular antimalarial drug.


phagostimulant

The infectious meal was prepared with fresh washed bovine red cells, viral supernatant (1:2) and adenosine triphosphate at 5 mM as phagostimulant.

2015 September 16, “Use of Centrifugal Filter Devices to Concentrate Dengue Virus in Mosquito per os Infection Experiments”, in PLOS ONE, →DOI:

(pharmacology) Any material that stimulates the production of phagocytes.


dolutegravir

From [Term?] + -tegravir (“HIV integrase inhibitor”).

Indeed, French regulations’ approval for the dolutegravir and the elvitegravir are posterior to the end of the data collection for this study.

2015 October 21, “Antiretroviral Regimens and CD4/CD8 Ratio Normalization in HIV-Infected Patients during the Initial Year of Treatment: A Cohort Study”, in PLOS ONE, →DOI:

(pharmacology) An integrase inhibitor used to treat HIV infections.


alexipharmac

Borrowed from Middle French alexipharmaque (modern French alexipharmaque (archaic)), and from its etymon Latin alexipharmacon (“antidote”) (whence Late Latin alexipharmacum), from Ancient Greek ἀλεξῐφᾰ́ρμᾰκον (alexĭphắrmăkon, “antidote; (generally) remedy; charm, spell”), a noun use of the neuter of ἀλεξῐφᾰ́ρμᾰκος (alexĭphắrmăkos, “acting as an antidote”), from ἀλέξειν (aléxein) (the active infinitive of ἀλέξω (aléxō, “to defend, guard, protect; to help; to keep off, turn aside, ward off”), ultimately from Proto-Indo-European *h₂lek- (“to protect”)) + φάρμᾰκον (phármăkon, “drug, whether healing or poisonous; charm, potion, spell; colour, dye”) + -ος (-os, suffix forming certain types of adjectives).

der

ἀλεξῐφᾰ́ρμᾰκον

/əˌlɛksɪˈfɑːmæk/

/əˌlɛksəˈfɑɹmæk/

(pharmacology, chiefly archaic or historical) A medical remedy for protecting the body, or an antidote, against a harmful substance, especially a poison or venom (specifically, that of a snake); an alexipharmic, an antidote.

alexipharmaque

medical remedy for protecting the body, or an antidote, against a harmful substance, especially a poison or venom — see also antidote


alexipharmac

en-adj

alexipharmac (comparative more alexipharmac, superlative most alexipharmac)

more alexipharmac (comparative)
most alexipharmac (superlative)

Borrowed from French alexipharmaque (archaic), and from its etymon Late Latin alexipharmacus, from Ancient Greek ἀλεξιφάρμακος (alexiphármakos) (see etymology 1).

der

ἀλεξιφάρμακος

/əˌlɛksɪˈfɑːmæk/

/əˌlɛksəˈfɑɹmæk/

(pharmacology, chiefly archaic or historical) Of or pertaining to an alexipharmac; also, acting as an alexipharmac by protecting against or warding off the ill effects of a harmful substance, especially a poison or venom; alexipharmic.

alexipharmaque

of or pertaining to an alexipharmac; acting as an alexipharmac


rifaximin

(pharmacology) A semisynthetic antibiotic based on rifamycin.


besifloxacin

From [Term?] + -floxacin (“nalidixic acid derivative”).

af

(pharmacology) A particular fluoroquinolone antibiotic.


fostemsavir

From fos- (“phosphorous derivative”) + temsavir.

(pharmacology) An experimental HIV entry inhibitor that is a prodrug of temsavir.


pradofloxacin

(pharmacology) A particular veterinary antibiotic of the fluoroquinolone class.


briakinumab

From -kin- (“interleukin”) + -umab (“human monoclonal antibody”).

As another interleukin 12/23 antagonist, briakinumab, was withdrawn from further development in part due to concerns about cardiovascular safety, discussion has also emerged on cardiovascular safety of ustekinumab.

2015 December 4, “Patient Preferences for Biologicals in Psoriasis: Top Priority of Safety for Cardiovascular Patients”, in PLOS ONE, →DOI:

rheumatoid arthritis
rheumatoid arthritis

(pharmacology) A human monoclonal antibody being developed to treat rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis.


deleobuvir

From [Term?] + -buvir (“RNA polymerase (NS5B) inhibitor”).

(pharmacology) An experimental drug for the treatment of hepatitis C.


ixekizumab

From [Term?] + -ki- (“interleukin”) + -zumab (“humanized monoclonal antibody”).

More recently, other biological drugs, such as ustekinumab, ixekizumab, tofacitinib, secukinumab and briakinumab, have targeted immunological mediators of the disease.

2015 December 12, “Evolution of Cooperation Patterns in Psoriasis Research: Co-Authorship Network Analysis of Papers in Medline (1942–2013)”, in PLOS ONE, →DOI:

(pharmacology) A humanized monoclonal antibody for the treatment of autoimmune diseases. It works by binding to interleukin 17 and blocking its action.


brodalumab

From -l- (“immunomodulating”) + -umab (“human monoclonal antibody”).

(pharmacology) A human monoclonal antibody designed to treat inflammatory diseases such as psoriasis.


luseogliflozin

From [Term?] + -gliflozin (“phlorizin derivative”).

To evaluate the cardiac safety of luseogliflozin, a thorough QT/QTc study was conducted in healthy Japanese subjects.

2015 October 8, “Randomized, Controlled, Thorough QT/QTc Study Shows Absence of QT Prolongation with Luseogliflozin in Healthy Japanese Subjects”, in PLOS ONE, →DOI:

(pharmacology) The thioglycoside 1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol that is used to treat diabetes


pentaquine

(pharmacology) Alternative form of pentaquin.


macitentan

From [Term?] + -entan (“endothelin receptor antagonist”).

Right and left ventricular collagen content was increased with pulmonary artery banding compared to sham-operated controls and ameliorated by macitentan.

2016 January 15, “Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload”, in PLOS ONE, →DOI:

(pharmacology) An endothelin receptor antagonist used to treat pulmonary arterial hypertension.


saroglitazar

/ˌsæɹ.əˈɡlɪt.əˌzɑɹ/

Probably from s(ulfanyl) + ar(yl) + -o- + -glitazar (“peroxisome proliferator activated receptors-α and -γ agonist”).

(pharmacology) A particular glitazar for the treatment of type 2 diabetes mellitus and dyslipidemia.


doxercalciferol

(pharmacology) A synthetic analogue of ergocalciferol, used as a drug to treat secondary hyperparathyroidism and metabolic bone disease.


selisistat

From [Term?] + -stat (“enzyme inhibitor”).

In contrast, a SIRT1 inhibitor, selisistat, has been reported to alleviate HD-related phenotypes in multiple HD models and has been found to be safe in clinical trials.

2016 January 28, “SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington’s Disease Mice”, in PLOS ONE, →DOI:

(pharmacology) A particular SIRT1 inhibitor drug.


triciribine

From tricy(clic) + -ribine (“ribofuranosyl derivative of the pirazofurin type”).

(pharmacology) A cell-permeable tricyclic nucleoside used to treat cancer.


cabotegravir

(pharmacology) An integrase inhibitor used to treat HIV infection.


brallobarbital

(pharmacology) A barbiturate drug, now disused because of its disagreeable side effects.


rupintrivir

From [Term?] + [Term?] + -vir (“antiviral”).

(pharmacology) A particular synthetic protease inhibitor used as an antiviral drug.


nonstimulant

A starch blocker is a nonstimulant, 100 per cent natural nutritional supplement derived from the white kidney bean.

2009 May 14, Malena Harbers, Toronto Star:

(pharmacology) Any substance that is not a stimulant.


angel dusting

(advertising, marketing, pharmacology) The misleading marketing practice of including a minuscule amount of an active ingredient in a product (such as food or cosmetics), insufficient to give any measurable benefit.


sonidegib

Among the inhibitors of the Hh pathway that interact directly with SMO, vismodegib and sonidegib are the two compounds approved by FDA in 2012 and 2015, respectively, for the treatment of basal cell carcinoma (BCC).

2016 March 3, “Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells”, in PLOS ONE, →DOI:

basal cell carcinoma
basal cell carcinoma

(pharmacology) A drug targeting the smoothened protein of the hedgehog signaling pathway, used for the treatment of basal cell carcinoma.


maribavir

From [Term?] + rib(osyl) + -a- + -vir (“antiviral”).

(pharmacology) An experimental antiviral drug for the prevention and treatment of human cytomegalovirus disease in transplant patients.


-sal

(pharmacology) Used to form names of salicylic acid derivatives.


fenestrel

(pharmacology) A synthetic, non-steroidal estrogen developed as a postcoital contraceptive in the 1960s but was marketed.


orestrate

From [Term?] + -estr- (“estrogen”) + -ate.

(pharmacology) A synthetic steroidal estrogen, the 3-propanoyl, 17-(1-cyclohexenyl) ether of estradiol.


finerenone

From [Term?] + -renone (“spironolactone derivative”).

If the FDA expands the use of finerenone as a heart failure therapy, cardiologist Dr. Michelle Bloom said, she would think about it as an option for her patients with mildly reduced or preserved ejection fraction.

2024 January 9, Jacqueline Howard, “Kidney disease medication found to reduce risk of cardiovascular death in certain heart failure patients in new study”, in CNN:

(pharmacology) A non-steroidal antimineralocorticoid in trials for the treatment of chronic heart failure.


estrapronicate

From estra(diol) + pro(pionate) + -nicate (“antihypercholesterolemic or vasodilating nicotinic acid ester”).

(pharmacology) Estradiol 17-nicotinate 3-propionate, a synthetic steroidal estrogen.


nilestriol

(pharmacology) A synthetic steroidal estrogen, the 3-cyclopentyl ether of 17α-ethinyl estriol.


methestrol

(pharmacology) A synthetic non-steroidal estrogen of the stilbestrol group.


fosfestrol

From phosph(ate) + -estr- (“estrogen”) + -ol.

(pharmacology) Diethylstilbestrol diphosphate, a synthetic non-steroidal estrogen of the stilbestrol group, used in the treatment of prostate cancer.


cloxestradiol

From (tri)chlo(ro) + (hydr)ox(y) + estradiol.

(pharmacology) A synthetic steroidal estrogen, an analogue of estradiol with a 2,2,2-trichloroethoxy substitution.


hexestrol

(pharmacology) A synthetic non-steroidal estrogen of the stilbestrol group, formerly used to treat estrogen deficiency.


arzoxifene

From [Term?] + [Term?] + -oxifene (“tamoxifen derivative”).

(pharmacology) A particular selective estrogen receptor modulator.


droloxifene

From (hy)dro(xy)l + -oxifene (“tamoxifen derivative”).

(pharmacology) A particular antiestrogen.


rolicyclidine

From (pyr)roli(dine) + cycl(ohexyl) + -clidine (“muscarinic receptor agonist/antagonist”).

(pharmacology) A dissociative anesthetic drug with hallucinogenic and sedative effects.


cinalukast

From [Term?] + -lukast (“leukotriene receptor antagonist”).

Using low scores for both R-enantiomer queries, the LBVS counter-screen ruled out exatecan acid, S-flunoxaprofen, gemfibrozil, cinalukast, fexofenadine, and tanomastat.

2015 November 12, “Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases”, in PLOS ONE, →DOI:

(pharmacology) The compound (E)-4-[[3-(2-(4-cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid that is used in the treatment of asthma


patritumab

From -tu- (“tumor”) + -umab (“human monoclonal antibody”).

For example, it has been demonstrated that cells overexpressing heregulin are sensitive to a combination of cetuximab and patritumab, an antibody against HER3, even though each antibody on its own is ineffective [18 ].

2015 November 17, “Combined Analysis of Plasma Amphiregulin and Heregulin Predicts Response to Cetuximab in Metastatic Colorectal Cancer”, in PLOS ONE, →DOI:

(pharmacology) A human monoclonal antibody designed for the treatment of cancer


pritelivir

(pharmacology) A particular antiherpetic drug.


laninamivir

From [Term?] + -amivir (“neuraminidase inhibitor”).

(pharmacology) A neuraminidase inhibitor used to treat influenza.


proarrhythmogenic

MicroRNAs are important mediators of proarrhythmogenic remodeling and have potential value as biomarkers in cardiovascular diseases.

2016 February 10, “MicroRNAs as Biomarkers for Acute Atrial Remodeling in Marathon Runners (The miRathon Study – A Sub-Study of the Munich Marathon Study)”, in PLOS ONE, →DOI:

(pharmacology) that promotes arrhythmogenesis


zoopharmacognosy

(zoology, pharmacology, medicine) The non-human knowledge and practise of medicine and medicaments (non-human animals' own knowledge, behaviours and culture, involving their own treatments of their own ailments).


pyramidon

From German Pyramidon, corresponding to pyr(azolone) + amid(e) + -on.

(pharmacology) A yellowish-white powder used as an antipyretic.


benralizumab

From [Term?] + [Term?] + -li- (“immunomodulating”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A monoclonal antibody being developed for the treatment of asthma.


fletikumab

From -k- (“interleukin”) + -umab (“human monoclonal antibody”).

(pharmacology) A monoclonal antibody designed for the treatment of rheumatoid arthritis.


perakizumab

From [Term?] + -ki- (“interleukin”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A humanized monoclonal antibody designed for the treatment of arthritis.


dinutuximab

(pharmacology) A particular monoclonal antibody


mesilate

mesilates (plural)
mesylate (alternative UK US)

When nafamostat mesilate (SK Chemicals Life Science Biz., Seoul, Korea licensed by Torii Pharmaceutical Co., LTD, Tokyo, Japan) was used for anticoagulation during the ECMO, the maintenance dose was held at 0.4–1.5 mg/kg/h to maintain a partial thromboplastin time of 60–80 s [ 12 ].

2015 August 17, Kun Il Kim et al., “The pre-ECMO simplified acute physiology score II as a predictor for mortality in patients with initiation ECMO support at the emergency department for acute circulatory and/or respiratory failure: a retrospective study”, in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, volume 23, →DOI:

(pharmacology) A salt or ester of an acid CH₄O₃S used especially in pharmaceutical preparations.


SARM

selective androgen receptor modulator#English

(pharmacology) Acronym of selective androgen receptor modulator.


spicelike

en-adj

spicelike (comparative more spicelike, superlative most spicelike)

more spicelike (comparative)
most spicelike (superlative)

The DEA has banned some basic types, but much research needs to be done. Some states have instituted bans on spice and spicelike products.

2016, Rosalind Charlesworth, Understanding Child Development:

(drugs) Like or resembling (in constitution, use, effects, etc.) spice (synthetic marijuana)


parapharmaceutical

(pharmacology) alternative to pharmaceutical


parapharmaceutical

alternative medicine
alternative medicine


DMARD

(pharmacology) Initialism of disease-modifying antirheumatic drug.


simtuzumab

From [Term?] + -tu- (“tumor”) + -zumab (“humanized monoclonal antibody”).

af

(pharmacology) A humanized monoclonal antibody designed for the treatment of fibrosis by binding to LOXL2 and acting as an immunomodulator.


moon rocks

(slang, drugs, plural only) A particularly strong preparation of cannabis.


tendamistat

From [Term?] + -stat (“enzyme inhibitor”).

(pharmacology) A protein that is a microbial inhibitor of α-amylase


levomilnacipran

(pharmacology) A serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders.


sudoxicam

(pharmacology) A particular benzothiazine carboxamide that is a cyclooxygenase inhibitor


para-acetylaminophenol

By surface analysis, para- + acetyl + aminophenol.

surf

(pharmacology) A pharmaceutical drug used to treat pain and fever


N-acetyl-p-aminophenol

(pharmacology) Synonym of para-acetylaminophenol (acetaminophen / paracetamol / tylenol)


examorelin

From hexa- + -morelin (“growth hormone release–stimulating peptide”).

af

(pharmacology) A particular synthetic hexapeptide.


bismuth subsalicylate

(pharmacology) An antacid medication C₇H₅BiO₄ (trademark Pepto-Bismol) taken orally to relieve diarrhea, nausea, and indigestion.


avilamycin

(pharmacology) Any of a class of orthosomycin antibiotics produced by the fermentation of Streptomyces viridochromogenes.


CTZ

(pharmacology) Initialism of cyclothiazide.


evernimicin

From everni(nate) + -micin (“aminoglycoside, antibiotic”).

(pharmacology) An oligosaccharide antibiotic of the orthosomycin group.


micromeritic

(pharmacology) Of or relating to small particles.


NVP

(pharmacology) Abbreviation of nevirapine.


nanopharmaceutical

(chiefly in the plural, pharmacology) Any pharmaceutical produced using nanotechnology, or manufactured in the form of nanoparticles.


antipanic

It has been suggested that antidepressants are effective as antipanic and antiphobic agents only in depressed patients[…]

2006, Paul J. Perry, Psychotropic drug handbook, page 314:

(psychology, pharmacology) Countering panic.


risocaine

From [Term?] + -caine (“local anesthetic”).

(pharmacology) The local anesthetic propyl 4-aminobenzoate.


NFV

(pharmacology) Abbreviation of nelfinavir.


nabiximols

Another marijuana-based drug, nabiximols (Sativex), is available in Canada and several European countries to treat spasticity and nerve pain in patients with multiple sclerosis.

2021 March 8, Jane E. Brody, “Medical Marijuana Is Not Regulated as Most Medicines Are”, in The New York Times:

(pharmacology) A specific extract of Cannabis that is approved for use as a botanical drug.


hot rail

(drugs) The act or practice of snorting vaporized drug fumes through a pipe, superheated at one end.


FPV

(pharmacology) Abbreviation of fosamprenavir.


metallopharmaceutical

(pharmacology) A pharmaceutical containing metal.


traphouse

(slang, drugs, African-American Vernacular) Alternative form of trap house.


meldonium

From [Term?] + -onium (“quaternary ammonium compound”).

(pharmacology) A drug used to treat ischemia, sometimes illicitly used by athletes to enhance performance.


antiautistic

en-adj

antiautistic (comparative more antiautistic, superlative most antiautistic)

more antiautistic (comparative)
most antiautistic (superlative)
anti-autistic (alternative)

[…] whereas for withdrawn, chronic schizophrenics who cut themselves off from the outside world he will tend to select a preparation having an anti-autistic effect.

1983, Rene Spiegel, Pyschopharmacology: An Introduction, page 5:

At higher doses, it is antiautistic, disinhibiting and resocializing, all effects useful in treating chronic psychoses.

1989, Harry Schwartz, Breakthrough: The Discovery of Modern Medicines at Janssen, page 78:

Those preparations prescribed in particularly small doses act not only anti-psychotic but also antiautistic.

1992, B. Luban-Plozza, W. Pöldinger, F. Kröger, Psychosomatic Disorders in General Practice, page 212:

(pharmacology, psychiatry, of a drug) Tending to reduce lethargy or withdrawn emotional states.


antialopecia

(medicine, pharmacology) A substance which counters the effects of alopecia.


dope house

(informal, drugs) A dwelling where drugs are either used or sold.


arterenol

(pharmacology) Synonym of norepinephrine.


azamethonium

From aza- + meth(yl) + -onium (“quaternary ammonium compound”).

af

(pharmacology) The cation ethyl-[2-[2-[ethyl(dimethyl)azaniumyl]ethyl-methylamino]ethyl]-dimethylazanium.


benzpyrinium

From benz(yl)pyr(id)ine + -ium (“quaternary ammonium compound”).

(pharmacology) The pyridinium cation 1-benzylpyridin-1-ium-3-yl N,N-dimethylcarbamate, the bromide of which is used to relieve postoperative urinary retention.


cactinomycin

en-noun

cactinomycin (countable and uncountable, plural cactinomycins)

(pharmacology) A particular actinomycin or a mixture of such materials.


cetylpyridinium

(organic chemistry, pharmacology) A cetyl derivative of the pyridinium cation that is the basis of several cationic disinfectants


PRR

proportional reporting ratio
proportional reporting ratio#English

(pharmacology) Initialism of proportional reporting ratio.


bazedoxifene

From [Term?] + aze(pane) + [Term?] + -oxifene (“tamoxifen derivative”).

af

(pharmacology) A SERM medication used to treat bone problems.


bemiparin

From [Term?] + -parin (“heparin derivative”).

(pharmacology) A particular antithrombotic.


abaloparatide

From [Term?] + para(thyroid) + -tide (“peptide, glycopeptide”).

(pharmacology) A parathyroid hormone-related protein (PTHrP) analogue drug used to treat osteoporosis.


pibrentasvir

From [Term?] + -asvir (“hepatitis C virus NS5A inhibitor”).

(pharmacology) An antiviral drug, used with glecaprevir to treat hepatitis C.


glecaprevir

From [Term?] + -previr (“hepatitis C virus protease inhibitor”).

(pharmacology) A protease inhibitor used to treat hepatitis C.


sitaxentan

From [Term?] + -entan (“endothelin receptor antagonist”).

(pharmacology) A drug for the treatment of pulmonary arterial hypertension.


velpatasvir

(pharmacology) An NS5A inhibitor used together with sofosbuvir in the treatment of hepatitis C.


voxilaprevir

(pharmacology) A hepatitis C virus nonstructural protein 3/4A protease inhibitor.


ibodutant

From [Term?] + -dutant (“neurokinin NK₂ receptor antagonist”).

irritable bowel syndrome
irritable bowel syndrome

(pharmacology) A candidate drug for irritable bowel syndrome diarrhea.


gemifloxacin

From [Term?] + -floxacin (“nalidixic acid derivative”).

(pharmacology) An oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of bronchitis and pneumonia.


deprenyl

Probably from d(im)e(thyl) + pr(opargyl) + (ph)en(eth)yl(amine).

(pharmacology) A monoamine oxidase inhibitor C₁₃H₁₇N used especially to treat Parkinson's disease.


cepharanthine

(organic chemistry, pharmacology) An antiinflammatory and antineoplastic biscoclaurine alkaloid isolated from Stephania - C₃₇H₃₈N₂O₆.


Narcan

Administering Narcan has nothing to do with getting an addict clean and sober. It has everything to do with saving a life in a given emergency.

2012, Peter L. Beilenson, Patrick A. McGuire, Tapping into The Wire, JHU Press, →ISBN:

(pharmacology) A marketed variety of naloxone.


Advil

en-proper noun

Advil (countable and uncountable, plural Advils)

two laps into our first walk, my dad needed to sit down. His back and legs were killing him. "You'll be okay," I assured him. "You just need to shake off the rust."
I gave him a couple of Advil and, after a few minutes, urged him back onto the track.

2008 October, Davy Rothbart, “How I caught up with dad”, in Men's Health, volume 23, number 8, →ISSN, page 110:

She handed Apple over two Advils, turned on the tap, and filled a glass of water, which she also handed her. “It will help. Trust me. Sailor does it all the time when she goes out in heels. She takes two Advils and swears she can last four hours longer on her feet.”

2010, Rebecca Eckler, chapter 4, in Apple’s Angst, Doubleday Canada, →ISBN, page 26:

“It’s not that I’m skeptical of pharmaceuticals—I love an Advil—but because of the cancer experience, I’ve also realized how amazing holistic medicine can be,” she says.

2023 June 15, Kat Moon, “Ashley Park’s Main Character Energy From ‘Joy Ride’ Is Here To Stay: ‘I’m Treating Myself Like A Lead Now’”, in Women's Health:

Milk thistle, calcium, high-rise, boot cut / Advil, black jeans, blue jeans

2024, “Bye Bye”, in The Collective, performed by Kim Gordon:

(pharmacology) A brand name for ibuprofen, a nonsteroidal anti-inflammatory drug.


brincidofovir

(pharmacology) An experimental antiviral drug, a prodrug of cidofovir.


rokitamycin

From [Term?] + translingual kata(satoensis) + -mycin (“antibiotic”).

af

(pharmacology) A macrolide antibiotic synthesized from Streptomyces kitasatoensis bacteria.


nesiritide

From nesi- (of unknown origin) + -ritide (“natriuretic peptide”).

(pharmacology) The recombinant form of the 32-amino acid human B-type natriuretic peptide, used to facilitate cardiovascular fluid homeostasis through counterregulation of the renin–angiotensin–aldosterone system.


ethacrynic acid

(organic chemistry, pharmacology) Alternative form of etacrynic acid.


sinapultide

From [Term?] + pul(monary) + -tide (“peptide, glycopeptide”).

(pharmacology) A synthetic peptide used in the drug lucinactant.


eucatropine

From euca(ine) + -trop- (“atropine derivative”) + -ine.


sodium pentothal

With the help of the D.A.'s sodium pentothal, hypnosis and some old-fashioned strong-arming, Russo then "remembered" that somebody "like" Clay Shaw, but under another name, was talked about.

1992 February 2, Mitzel, “Clay Shaw, The Quean Network & That Kennedy Killing”, in Gay Community News, volume 19, number 28, page 12:


murabutide

From mura(myl) + but- + -tide (“peptide, glycopeptide”).

(pharmacology) A synthetic immunomodulator derived from muramyl dipeptide, the smallest bioactive unit of bacterial peptidoglycan.


oxybate

(organic chemistry, pharmacology) Contraction of gamma-hydroxybutyrate.


nembutal

Nearly every pharmaceutical house has its own brands, sold in tablets, solutions or brightly-colored capsules, on which its “detail men” keep doctors informed. Probably the most popular successors to Veronal are Seconal (“red birds” to the bootleg trade) and Nembutal (“yellow jackets”).

1952 October 13, Richard L. Williams, “‘To sleep: perchance…’”, in Life, volume 33, number 15, page 110:

(pharmacology) A trade name of pentobarbital.


Savlon

en-noun

Savlon (countable and uncountable, plural Savlons)

(pharmacology) a brand of antiseptic cream or gel marketed in the United Kingdom and elsewhere.


holocaine

In the absence of cocaine, I'd recommend holocaine.

2014 October 10, Steven Katz, “The Golden Lotus”, in The Knick, season 1, episode 9, spoken by Dr. Bertram "Bertie" Chickering, Jr. (Michael Angarano):


artemisone

(pharmacology) An antimalarial drug derived from artemisinin.


artelinic acid

(organic chemistry, pharmacology) An experimental drug that may have some antimalarial activity


d/c

Do not d/c abruptly.

(medicine, pharmacology) Abbreviation of discontinue.

(medicine, pharmacology) Abbreviation of discharge.


picotamide

peripheral artery disease
peripheral artery disease

(pharmacology) A thromboxane synthase inhibitor and a thromboxane receptor inhibitor used in the treatment of clinical arterial thrombosis and peripheral artery disease.


dapivirine

From [Term?] + -virine (“nonnucleoside reverse transcriptase inhibitor”).

af

(pharmacology) An antiretroviral drug 4-{[4-(mesitylamino)-2-pyrimidinyl]amino}benzonitrile used to prevent HIV infection in women.


idarucizumab

From idaru- (of unknown origin) + -ci- (“cardiovascular”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A monoclonal antibody designed for the reversal of anticoagulant effects of dabigatran.


neosynephrine

The method of anesthetizing the mother is as follows: […] The mother is given ¼ cc. of neosynephrine intramuscularly immediately and the blood pressure taken.

1951 February, Forrest H. Howard, “The Physiologic Position for Delivery”, in Northwest Medicine, volume 50, number 2, Portland, Ore.: Northwest Medical Publishing Association, page 99:

(pharmacology) Synonym of phenylephrine.


glitazar

/ˈɡlɪt.əˌzɑɹ/

From -glitazar (“dual peroxisome proliferator activated receptors-α and -γ agonist”).

(pharmacology) Any of a class of drugs used to control diabetes.


antiarrhythmogenic

(pharmacology) That counters arrhythmogenesis


dupilumab

From -l- (“immunomodulating”) + -umab (“human monoclonal antibody”).

(pharmacology) A monoclonal antibody designed for the treatment of allergic diseases such as eczema.


vanc

(pharmacology, slang) Clipping of vancomycin.


redose

en-verb

redose (third-person singular simple present redoses, present participle redosing, simple past and past participle redosed)

redoses (present singular third-person)
redosing (participle present)
redosed (participle past)
redosed (past)

(transitive, medicine, especially pharmacology) To dose again: to give a subsequent dose.


zoniporide

(pharmacology) The compound N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide that inhibits ion exchange


ozogamicin

From [Term?] + -micin (“aminoglycoside, antibiotic”).

af

monoclonal antibodies
monoclonal antibody

(pharmacology) Any of a certain group of monoclonal antibodies.


peg-

From PEG, the initialism of polyethylene glycol.

(biochemistry, pharmacology) Used to form names of PEGylated molecules.


methylpred

(biochemistry, pharmacology, colloquial) Methylprednisolone.


-vir

carbovir

(pharmacology) Used to form names of generic antivirals.


-vudine

lamivudine, stavudine, telbivudine

(pharmacology) Used to form names of antineoplastics and antivirals of the zidovudine type


-azepam

(pharmacology) Used to form names of diazepam derivatives.


-azodone

(organic chemistry, pharmacology) Used to form names of generic antidepressant drugs.


-azosin

(pharmacology) Used to form names of prazosin derivatives used as antihypertensive substances.


-afil

w:cGMP-specific phosphodiesterase type 5

(pharmacology) Used to form names of inhibitors of phosphodiesterase PDE5 with vasodilator action.


-asone

betamethasone, dexamethasone, diflorasone, fluticasone, mometasone

(biochemistry, pharmacology) Used to form names of generic corticosteroid drugs.


-rubicin

doxorubicin, epirubicin, idarubicin, valrubicin

(pharmacology) Used to form names of daunorubicin derivatives used as antineoplastics.


-bital

butalbital, vinylbital

(pharmacology) Used to form generic names of barbiturate drugs.


-cillin

amoxicillin, ampicillin, dicloxacillin, nafcillin, oxacillin

(pharmacology) Used to form names of generic penicillin antibiotic drugs.


-cycline

demeclocycline, doxycycline, minocycline, tetracycline

(pharmacology) Used to form names of generic tetracycline antibiotic drugs.


-dazole

albendazole, mebendazole, metronidazole, tinidazole

(pharmacology) Used to form names of generic anthelmintic or antibiotic drugs.


-dipine

calcium channel blocker
calcium channel blocker#English

(pharmacology) Used to form names of generic calcium channel blocker drugs which are nifedipine derivatives.


-dronate

alendronate, etidronate, ibandronate, risedronate

(pharmacology) Used to form nonproprietary names for bisphosphonate drugs.


-prazole

(pharmacology) Used to form names of benzimidazole derivatives used as antiulcers.


-fenac

bromfenac, diclofenac, nepafenac

(pharmacology) Used to form names of ibufenac derivatives used as generic nonsteroidal anti-inflammatory drugs.


-floxacin

besifloxacin, ciprofloxacin, levofloxacin, moxifloxacin, ofloxacin

(pharmacology) Used to form names of generic fluoroquinolone antibiotics


-gliptin

From gli- (“antihyperglycemic”) + (pe)pt(idase) + in(hibitor).

saxagliptin, sitagliptin, linagliptin

dipeptidyl peptidase-4
w:dipeptidyl peptidase-4

(pharmacology) Used to form generic names of dipeptidyl peptidase-4 inhibitor antidiabetic drugs.


salicylsalicylic acid

(organic chemistry, pharmacology) The conjugate acid of salicylsalicylate.

salicylsalicylate

coordinate as a base versus an acid, but synonymous in the practical sense that the conjugate base and conjugate acid coexist in solution


pseudopharmaceutical

LL-Q1860 (eng)-Flame, not lame-pseudopharmaceutical.wav

(pharmacology) Apparently, but not actually, pharmaceutical.


pseudopharmaceutical

(pharmacology) Any substance that only appears to, or is claimed to, have pharmaceutical effects.


nosiheptide

From [Term?] + [Term?] + -tide (“peptide, glycopeptide”).

(pharmacology) A particular macrocyclic thiopeptide antibiotic.


seglitide

(pharmacology) A methylated cyclopeptide cyclo[N-methyl-ʟ-alanyl-ʟ-tyrosyl-ᴅ-tryptophyl-ʟ-lysyl-ʟ-valyl-ʟ-phenylalanyl] which inhibits growth hormone secretion.


clazosentan

From [Term?] + -entan (“endothelin receptor antagonist”).

(pharmacology) A sulfonamide drug, N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamide, that controls vasospasm.


onapristone

From ona- (of unknown origin) + (mife)pristone.

(pharmacology) A synthetic antiprogestogen used to combat prostate cancer.


albondin

(pharmacology, biochemistry) A cell receptor that binds albumin.


phytopharmacologic

(pharmacology) Alternative form of phytopharmacological.


reprotoxicity

en-noun

reprotoxicity (countable and uncountable, plural reprotoxicities)

(pharmacology, toxicology) The condition of being reprotoxic


amphoterrible

A few days later he was in the ICU candida growing out of everywhere. If it hadn' been for amphoterrible, he'd have been a dead duck.

1999 October 1, Steven B. Harris, “Re: Flu Shot Time Again”, in misc.health.alternative (Usenet):

Dr. Cheng said, “I want you to just nod or shake your head. If I can't understand you, we'll go to Fiona, alright? I want to know if I have your okay to take you off the pentam and the amphoterrible. That means we'd be officially starting hospice. And I want you on morphine.”

2018, Rebecca Makkai, The Great Believers, Viking Press, →ISBN:

(informal, mildly humorous, pharmacology) The antifungal medication amphotericin B, known for its severe and potentially lethal side effects.


cenderitide

From [Term?] + -ritide (“natriuretic peptide”).

af

(pharmacology) A chimeric natriuretic peptide used to treat heart failure.


RTX

(pharmacology) Abbreviation of rituximab.


sipatrigine

From [Term?] + -trigine (“signal transduction modulator”).

(pharmacology) The neuroprotective agent 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine.


neuropharmaceutical

(medicine, pharmacology) Any drug used to treat a neurological disorder


subpsychotomimetic

(pharmacology, of a dosage) That is insufficient to have a psychotomimetic effect


capravirine

reverse transcriptase
reverse transcriptase

(pharmacology) A nonnucleoside reverse transcriptase inhibitor [5-(3,5-dichlorophenyl)sulfanyl-4-propan-2-yl-1-(pyridin-4-ylmethyl)imidazol-2-yl]methyl carbamate.


rifamide

en-noun

rifamide (countable and uncountable, plural rifamides)


valopicitabine

From Val + -o- + [Term?] + -citabine (“cytarabine or azacytidine derivative”).

af

(pharmacology) The prodrug [(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan-3-yl] (2S)-2-amino-3-methylbutanoate.


reprotoxicant

(pharmacology, toxicology) Any reprotoxic material


clazakizumab

From [Term?] + -ki- (“interleukin”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) An investigational drug, an aglycosylated, humanized rabbit monoclonal antibody against interleukin-6.


monalizumab

From [Term?] + -li- (“immunomodulating”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) An investigational drug for the treatment of rheumatoid arthritis, gynecologic malignancies and other cancers.


gamithromycin

(pharmacology) A macrolide antibiotic used to treat bovine respiratory disease.


porfiromycin

(pharmacology) An antineoplastic antibiotic, [(4S,6S,7R,8S)-11-amino-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate.


rivoglitazone

From [Term?] + -glitazone (“thiazolidinedione derivative”).

(pharmacology) A thiazolidinedione derivative used to treat diabetes.


rotigaptide

(pharmacology) A peptide analog used in the treatment of cardiac arrhythmia.


lobeglitazone

(pharmacology) A particular thiazolidinedione antidiabetic drug.


leminoprazole

From [Term?] + -prazole (“benzimidazole derivative”).

(pharmacology) The benzimidazole drug 2-(1H-benzimidazol-2-ylsulfinylmethyl)-N-methyl-N-(2-methylpropyl)aniline.


sartan

From s(elective) + a(ngiotensin) + r(ecep)t(or) + an(tagonist).

(pharmacology) Any of a group of angiotensin receptor antagonists that are used in the treatment of hypertension.


isatoribine

From [Term?] + -ribine (“ribofuranosyl derivative of the pirazofurin type”).

(pharmacology) The antiviral nucleoside 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-[1,3]thiazolo[4,5-d]pyrimidine-2,7-dione.


gimeracil

From [Term?] + -racil (“uracil type antineoplastic”).

(pharmacology) The compound 5-chloro-2,4-dihydroxypyridine used in the treatment of gastric cancer.


mericitabine

From [Term?] + -citabine (“cytarabine or azacytidine derivative”).

(pharmacology) A particular antiviral drug.


DRV

(pharmacology) Abbreviation of darunavir.


vental

(pharmacology) Synonym of phenylpropanolamine.


reprotoxicological

(pharmacology, toxicology) Relating to the toxicology of reprotoxicants


rifametane

From rifa- (“rifamycin derivative”) + methane.

(pharmacology) The antibiotic 3-azinomethyl-rifamycin.


tenzide

(organic chemistry, pharmacology) Synonym of hydrochlorothiazide.


tezacitabine

(pharmacology) The ribonucleotide reductase inhibitor 4-amino-1-[(2R,3E,4S,5R)-3-(fluoromethylidene)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one.


-toin

(pharmacology) Used to form names of hydantoin derivatives used as antiepileptics.


immunopharmaceutical

(pharmacology) immunological and pharmaceutical


immunopharmaceutical

(pharmacology) Any such drug (typically a modified protein)


SEGRA

glucocorticoid receptor
glucocorticoid receptor#English

(pharmacology) Acronym of selective glucocorticoid receptor agonist.


doranidazole

From [Term?] + -nidazole (“metronidazole derivative”).

(pharmacology) The anticancer drug (2R,3S)-3-[(2-nitroimidazol-1-yl)methoxy]butane-1,2,4-triol.


tezosentan

[Term?] + -entan (“endothelin receptor antagonist”)


evogliptin

From [Term?] + -gliptin (“dipeptidyl aminopeptidase-IV inhibitor”).

(pharmacology) A particular antidiabetic drug.


ibufenac

From i(so)bu(tyl) + -fenac (“phenyl acetate”).

(pharmacology) The carboxylic acid 4-isobutylphenylacetic acid once used in the treatment of rheumatoid arthritis


octisalate

(pharmacology) The ester octyl salicylate when used as a sunscreen.


efinaconazole

From [Term?] + -conazole (“miconazole derivative”).

(pharmacology) A particular antifungal triazole.


trelagliptin

(pharmacology) A pharmaceutical drug used for the treatment of diabetes mellitus.


balaglitazone

(pharmacology) A thiazolidinedione derivative that shows antihyperglycemic activity.


carperitide

[Term?] + -ritide (“natriuretic peptide”)

atrial natriuretic peptide
atrial natriuretic peptide

(pharmacology) A recombinant atrial natriuretic peptide.


dalazatide

From [Term?] + [Term?] + -tide (“peptide, glycopeptide”).

(pharmacology) A synthetic peptide used to treat multiple sclerosis.


Eroom's law

Moore's law spelled backwards, coined in a 2012 paper.

Eroom's Law, in turn, observes that in the pharmaceutical sector the decline in innovation is itself constant: the yield of FDA-approved drugs per billion dollars spent has halved every nine years between 1950 and 2010.

2014, Jeremy A. Greene, Generic: The Unbranding of Modern Medicine, JHU Press, →ISBN, page 271:

With a touch of wry humour, the authors dubbed this phenomenon Eroom's law, the reverse spelling of Moore's Law – the famous law of computing that expresses the doubling of processing power per dollar every two years […]

2018, Mark Stevenson, We Do Things Differently: The Outsiders Rebooting Our World, Abrams, →ISBN:

(pharmacology) The observation that drug discovery is becoming slower and more expensive over time, despite improvements in technology.


semaglutide

en-noun

semaglutide (countable and uncountable, plural semaglutides)

LL-Q1860 (eng)-Naomi Persephone Amethyst (NaomiAmethyst)-semaglutide.wav

From sema- + -glutide (“glucagon-like peptide analog”).

af

Last year, the situation began to change when Novo Nordisk received approval from the Food and Drug Administration to market semaglutide. The drug can elicit a 15 percent to 17 percent weight loss in people with obesity.

2022 April 28, Gina Kolata, “Patients Taking Experimental Obesity Drug Lost More Than 50 Pounds, Maker Claims”, in The New York Times, →ISSN:

But now a new generation of medications has arrived, based on a better understanding of the biological underpinnings of obesity. […] One of these medications – semaglutide, sold under the brand name Wegovy – will soon be available in UK chemists in the form of a weekly, self-administered injection.

2023 February 23, Jason Halford, “It may be the most effective anti-obesity drug yet – but even Wegovy is no ‘wonder cure’”, in The Guardian, →ISSN:

As semaglutide has skyrocketed in popularity, patients have been sharing curious effects that go beyond just appetite suppression. They have reported losing interest in a whole range of addictive and compulsive behaviors: drinking, smoking, shopping, biting nails, picking at skin.

2023 May 19, Sarah Zhang, “Ozempic’s Next Act”, in The Atlantic:

The heart of the growth is semaglutide, Novo Nordisk’s synthetic version of a hormone known as glucagon-like peptide 1, or GLP-1, which helps the body regulate blood sugar levels.

2024 April 20, Eshe Nelson, Charlotte de la Fuente, “It Introduced Ozempic to the World. Now It Must Remake Itself.”, in The New York Times, →ISSN:

(pharmacology) A peptide used in the treatment of diabetes and as an antiobesity medication.


iodophthalein

In approximately one-half of the cases, Priodax preceded iodophthalein and vice versa. The percentage of fair and good shadow results is almost identical with the two drugs, being 71.9 per cent for Priodax and 72.5 per cent for iodophthalein.

1944, RSNA Index to Imaging Literature, volume 42, page 229:

The preparation of the patient was exactly the same as had previously been practised with sodium iodophthalein. The usual lunch was given on the day before the examination. The evening meal was fat-free.


trospium

From tro(pane) + spi(ro) + -ium (“quaternary ammonium compound”).

(pharmacology) A drug used to treat overactive bladder.


antiflatus

(pharmacology) Serving to prevent flatus.


low-T

In recent years, many in this world have become obsessed with the idea that conservative guys are jacked, masculine, high-T GigaChads while liberals are weak, emasculated, low-T Soy Boys.

2023 April 5, Mark Hay, “Does Testosterone Affect Your Politics?”, in VICE:

(medicine, pathology, euphemistic, pharmacology marketing) Abbreviation of low testosterone (“A medical condition in men where testosterone levels are low, and associated with low physique, motivation and virility”).


venetoclax

(pharmacology) A drug used to treat leukemia.


naloxegol

From nal- (“opioid receptor antagonist/agonist”) + [Term?] + -ol.

(pharmacology) A particular opioid receptor antagonist.


rufloxacin

From [Term?] + -floxacin (“nalidixic acid derivative”).

(pharmacology) The antibiotic 7-fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.0^(5,13)]trideca-5(13),6,8,11-tetraene-11-carboxylic acid.


KF

(pharmacology) Initialism of ketotifen fumarate.


remdesivir

/ɹɛmˈdɛs.ɪˌvɪə(ɹ)/

From [Term?] + -desi- (“adenosine analog”) + -vir (“antiviral”).

(pharmacology) A novel antiviral drug (C₂₇H₃₅N₆O₈P) with activity against a wide range of single-stranded RNA viruses, indicated for the treatment of COVID-19.


HCQ

(pharmacology) Abbreviation of hydroxychloroquine.


batefenterol

From [Term?] + [Term?] + -terol (“phenethylamine derivative”).

(pharmacology) A particular muscarinic antagonist.


NRTI

reverse transcriptase
reverse transcriptase#English

(pharmacology) Initialism of nucleoside reverse transcriptase inhibitor; as opposed to NtRTIs.

(pharmacology) Initialism of nucleoside or nucleotide reverse transcriptase inhibitor.


NtRTI

(pharmacology) Initialism of nucleotide reverse transcriptase inhibitor.


NNRTI

(pharmacology) Initialism of non-nucleoside reverse transcriptase inhibitor.


ZDV

(pharmacology) Abbreviation of zidovudine.


ddI

(pharmacology) Abbreviation of dideoxyinosine; also DDI.


ETR

(pharmacology) Abbreviation of etravirine.


DLV

(pharmacology) Abbreviation of delavirdine.


SQV

(pharmacology) Abbreviation of saquinavir.


IDV

en-noun

IDV (countable and uncountable, plural IDVs)

(pharmacology) Abbreviation of indinavir.


RTV

(pharmacology) Abbreviation of ritonavir.


fosbretabulin

From fos- (“phosphorous derivative”) + [Term?] + -bulin (“tubulin binder”).

af

(pharmacology) A combretastatin phosphate, present in Combretum caffrum that has antineoplastic activity


olaratumab

From -tu- (“tumor”) + -umab (“human monoclonal antibody”).

(pharmacology) A particular monoclonal antibody.


olodaterol

From [Term?] + -terol (“phenethylamine derivative”).


atezolizumab

From [Term?] + -li- (“immunomodulating”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) An monoclonal antibody used in immunotherapy.


guadecitabine

(pharmacology) A guanoside of decitabine that has antineoplastic activity.


Cialis

(trademark, pharmacology) A preparation for tadalafil.


microneedle array

en-noun

microneedle array (plural microneedle arrays)

(medicine, pharmacology) A drug delivery patch composed of an array of microscopic needles that inject the drug over a contact area.


Versed

When the delirium stopped and it was safe to take Versed, her doctors doped her up and she managed to endure the MRI, on condition that I remain with her all the time.

2005, Donald Hall, The Best Day the Worst Day: Life with Jane Kenyon, Boston: Houghton Mifflin Company, →ISBN, page 99:

(pharmacology) A marketed variety of midazolam.


transungual

transungual drug delivery system

(chiefly pharmacology) Through the nail plate.


amoxi

A few weeks later I started having some upper respiratory problems with young kittens, most of whom come in the springtime. I used amoxi and normal methods of clearing this up but it got worse. I consulted with Dr. Tom Sampson, our veterinarian from Mt. Shasta Animal Hospital, who started stronger treatment.

1996, Cat Fanciers' Almanac, volume 12, page 98:

(informal, pharmacology) Clipping of amoxicillin.


cross-resistance

cross-resistance (countable and uncountable, plural cross-resistances)

cross-resistances (plural)
crossresistance (alternative)
cross resistance (alternative)

Cross-resistance between antibiotics of the same class can occur frequently.

(pharmacology, toxicology) The tolerance to a usually toxic substance stimulated by former exposure to a structurally similar substance.


INSTI

(pharmacology) Initialism of integrase strand transfer inhibitor.


TDM

(pharmacology) Initialism of therapeutic drug monitoring.


VBL

Vincristine [vin-KRIS-teen] (VX) and vinblastine [vin-BLAS-teen] (VBL) are structurally related compounds derived from the periwinkle plant, Vinca rosea. […] VBL is administered with bleomycin and cisplatin for the treatment of metastatic testicular carcinoma.

2015, Kourtney LaPlant, Paige Louzon, “Anticancer Drugs”, in Karen Whalen, Richard Finkel, Thomas A. Panavelil, editors, Lippincott Illustrated Reviews: Pharmacology, 6th edition, Wolters Kluwer, →ISBN, page 603:

(pharmacology) Abbreviation of vinblastine.


Hetrazan

(trademark, medicine, pharmacology) A preparation of diethylcarbamazine citrate.


VRB

VRB (countable and uncountable, plural VRBs)

A less neurotoxic agent is vinorelbine [vye-NOR-el-been] (VRB). […] VRB is beneficial in the treatment of advanced non–small cell lung cancer, either as a single agent or with cisplatin.

(pharmacology) Abbreviation of vinorelbine.


brexpiprazole

From [Term?] + -piprazole (“phenylpiperazine derivative”).

af

(pharmacology) The antipsychotic 7-[4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy]quinolin-2(1H)-one.


cook back

en-verb

cook back (third-person singular simple present cooks back, present participle cooking back, simple past and past participle cooked back)

cooks back (present singular third-person)
cooking back (participle present)
cooked back (participle past)
cooked back (past)

(transitive, drugs) To recook a drug (especially crack cocaine) in an aqueous solution (water) in order to remove excess adulterants, thereby purifying it.


ara-C

cytosine arabinoside
cytosine arabinoside#English

(pharmacology) Abbreviation of cytosine arabinoside.


MLSB

Staphylococcus aureus
Staphylococcus aureus#Translingual

(pharmacology) Initialism of macrolide, lincosamide and streptogramin B: three classes of antibiotics, against which certain bacteria, such as Staphylococcus aureus, may develop a cross-resistance phenotype.


rimexolone

From [Term?] + [Term?] + -olone (“steroid or steroid-like drug”).

af

(pharmacology) A glucocorticoid steroid used to treat inflammation of the eye.


Vicodin

en-proper noun

Vicodin (countable and uncountable, plural Vicodins)

Brand name. From Vi (of unknown origin) + cod- (in codeine) + -in. One theory is that Vi is from the Roman numeral VI, as the component hydrocodone is approximately 6 times as potent as codeine.

Listen. You give 'em a Percocet, two Vicodin and a couple of beers, and the panties drop. It's very nice.

1999, W. Peter Iliff, Varsity Blues, spoken by Charlie Tweeder (Scott Caan):

In a statement, Carlin, 67, said, "I'm going into rehab because I use too much wine and Vicodin. No one told me I needed this; I recognized the problem and took the step myself.

2004 December 27, George Carlin, quotee, “George Carlin enters rehab”, in CNN.com, archived from the original on 2017-10-19:

Man, I swear my nigga trippin' off that shit again / Pick him up, then I set him in cold water / Then I order someone to bring him Vicodin / I hope that take the pain away

2011, “A.D.H.D.”, in Section.80, performed by Kendrick Lamar:

Teens may assume that it's safe to use Vicodin and OxyContin because these drugs are available legally by prescription (unlike marijuana, cocaine, and other illicit drugs). If a doctor ordered the drug for one of your family members, it can't be dangerous, right?

2013, Christine Petersen, Vicodin and OxyContin, Cavendish Square Publishing, LLC, →ISBN:

Gonna call in sick to work, I don’t care, my boss is a jerk / Can’t believe all the pain I’m in, get me white wine and vicodin

2014, “Crimson Wave”, in NVM, performed by Tacocat:

(pharmacology) A brand name for an analgesic combination drug containing hydrocodone and paracetamol, often used for recreational purposes.


apalutamide

From [Term?] + -lutamide (“nonsteroid antiandrogen”).

af

(pharmacology) A nonsteroidal antiandrogen used to treat prostate cancer.


camrelizumab

From [Term?] + [Term?] + -li- (“immunomodulating”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A particular anticancer drug.


darolutamide

(pharmacology) An antiandrogen used against prostate cancer.


emicizumab

From [Term?] + -ci- (“cardiovascular”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A chimeric bispecific antibody used in the treatment of haemophilia.


galcanezumab

From [Term?] + -ne- (“neural”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A monoclonal antibody against CGRP used to treat migraine.


SABA

(pharmacology) Initialism of short-acting beta-adrenoceptor agonist, a drug class used in the treatment of respiratory diseases.


LTRA

(pharmacology) Initialism of leukotriene receptor antagonist.


lukast

Back-formation from -lukast (suffix), from -ast.

Leukotriene pathway inhibitors, such as zileuton or the lukasts (cysteinyl leukotriene receptor antagonists), block the development of both systemic symptoms and bronchial obstruction.

1999, William J. Calhoun, “Asthma”, in Gerald S. Davis, editor, Medical Management of Pulmonary Diseases, New York, NY: Marcel Dekker, →ISBN, page 448:

(pharmacology) Any of several antagonists of the cysteinyl leukotriene receptor 1, used in the treatment of respiratory diseases such as asthma, which has a name ending in -lukast.


Percocet

en-prop

Percocet (countable and uncountable, plural Percocets)

/ˈpɜɹkəˌsɛt/

They ingest Ambien, Seroquel, LSD, Adderall, Oxycodone, cocaine, Flexeril, Percocet, psilocybin mushrooms and codeine.

2013 June 4, Dwight Garner, “A Literary Mind, Under the Spell of Drugs and a MacBook”, in The New York Times, →ISSN:

(pharmacology) A brand name for an analgesic combination drug containing oxycodone and paracetamol, often used for recreational purposes.


omaveloxolone

From o(leanane) + [Term?] + [Term?] (“steroid or steroid-like drug”) + -olone.


pidilizumab

(pharmacology) A particular monoclonal antibody.


povidone-iodine

(pharmacology) A mixture of iodine and povidone which is less toxic than iodine by itself, used as an antiseptic for skin disinfection.

聚維酮碘 /聚维酮碘

mixture of iodine and povidone used as an antiseptic


HQC

en-noun

HQC (countable and uncountable, plural HQCs)

(pharmacology) Abbreviation of hydroxyquinolinecarbonyl.


rtPA

From r (“recombinant”) + tPA (“tissue plasminogen activator”).

af

tissue plasminogen activator
tissue plasminogen activator#English

(biochemistry, pharmacology) Initialism of recombinant tissue plasminogen activator.


binimetinib

From bini- (a unique prefix) + -metinib (suffix indicating an inhibitor of mitogen-activated protein kinase kinase (MEK)).

affix

Binimetinib (MEK162; ARRY-438162) is a potent, adenosine triphosphate-uncompetitive, highly selective allosteric inhibitor of MEK1/2 with demonstrated on-target activity in vitro and in vivo, including models of cancer [...] In vivo, binimetinib displays broad anti-tumour activity in xenograft models derived from melanoma, colorectal cancer, non-small cell lung cancer (NSCLC), fibrosarcoma, cholangiocarcinoma, and pancreatic cancer. These non-clinical data support the use of binimetinib in a wide variety of tumour types, with a priority in tumours with aberrantly activated MAPK pathway signalling.

2017 February 28, Johanna C. Bendell et al., “A Phase 1 Dose-escalation and Expansion Study of Binimetinib (MEK162), a Potent and Selective Oral MEK1/2 Inhibitor”, in British Journal of Cancer, volume 116, Edinburgh: Nature Research, →DOI, →ISSN, →OCLC, page 576, column 1:

Binimetinib improved progression-free survival compared with dacarbazine and was tolerable. Binimetinib might represent a new treatment option for patients with NRAS-mutant melanoma after failure of immunotherapy.

2017 April 1, Reinhard Dummer et al., “Binimetinib versus Dacarbazine in Patients with Advanced NRAS-mutant Melanoma (NEMO): A Multicentre, Open-label, Randomised, Phase 3 Trial”, in David Collingridge, editor, The Lancet Oncology, volume 18, number 4, London: Lancet Publishing Group, →DOI, →ISSN, →OCLC, pages 435–445:

Under development are binimetinib, a MEK inhibitor being studied in patients with NRAS-mutant melanoma, and encorafinib, a BRAF inhibitor being used in combination with binimetinib for patients with BRAF-mutant melanoma.

2018, Laurence Brunton, Bjorn Knollman, Randa Hilal-Dandan, Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 13th edition, New York, N.Y.: McGraw Hill Professional, →ISBN, page 1212:

The initial report of the phase I/II combination trial of encorafenib and binimetinib reported on 9 BRAF inhibitor naive and 14 BRAF inhibitor pretreated patients with metastatic BRAF mutant melanoma across a range of doses.

2018, Shane Y. Morita et al., Textbook of General Surgical Oncology, New York, N.Y.: McGraw Hill Professional, →ISBN, page 187:

Binimetinib is an oral reversible inhibitor of mitogen-activated extracellular signal-regulated kinase (MEK) 1/2. [...] Binimetinib inhibits MEK 1/2 downstream from BRAF and halts cancer cell signaling and survival. [...] Binimetinib is approved in combination with encorafenib, a BRAF inhibitor, for the treatment of unresectable or metastatic melanoma with a BRAF V600E/K mutation, as detected by an FDA-approved test.

2019 July 20, Heidi Finnes, “Binimetinib (Mektovi®)”, in Oncology Times: The Newspaper for Specialists in Cancer, volume 41, number 14, Philadelphia, Pa.: Lippincott Williams & Wilkins, →DOI, →ISSN, →OCLC, page 8:

Special Considerations [...] 7. Monitor patients for an increased risk of new primary cancers, both cutaneous and non-cutaneous, while on therapy and for up to 6 months following the last dose of binimetinib. [...] 10. Baseline and periodic CPK levels while on therapy, as rhabdomyolysis has been observed with binimetinib therapy.

2020, Edward Chu, Vincent T[heodore] DeVita, Jr., “Chemotherapeutic and Biologic Drugs”, in Physicians’ Cancer Chemotherapy Drug Manual 2021, Burlington, Mass.: Jones & Bartlett Learning, →ISBN, →ISSN, page 77:

Binimetinib is given in combination with encorafenib as each drug targets a different kinase in the RAS/RAF/MEK/ERK pathway to stop malignant cell proliferation and to tell the cells to die (undergo apoptosis). [...] Terminal half-life of binimetinib is 3.5 hours. [...] No clinically significant changes in binimetinib exposure were seen in patients with severe renal impairment.

2020, Gail M. Wilkes, Margaret Barton-Burke, “Molecular Targeted Therapy”, in Oncology Nursing Drug Handbook 2020–2021, Burlington, Mass.: Jones & Bartlett Learning, →ISBN, →ISSN, page 548:

mitogen-activated protein kinase kinase
mitogen-activated protein kinase kinase

(pharmacology) A drug with the molecular formula C₁₇H₁₅BrF₂N₄O₃ that inhibits mitogen-activated protein kinase kinase (MEK), and is approved for use in combination with encorafenib to treat certain melanomas.

בינימטיניב

drug that inhibits mitogen-activated protein kinase kinase


pemafibrate

From [Term?] + -fibrate (“clofibrate derivative”).

af

(pharmacology) A drug that modulates peroxisome proliferator-activated receptors


baloxavir

From [Term?] + oxa- + -vir (“antiviral”).

(pharmacology) A particular antiviral medication used to treat influenza.


neuroanabolic

(pharmacology) Promoting anabolism in the nervous system.


mood stabiliser

en-noun

mood stabiliser (plural mood stabilisers)

mood stabilisers (plural)
mood stabilizer (alternative)

Lithium has been used as a mood stabiliser for 50 years but its action mechanism is still unclear.

2008, Barbara Kozier, Fundamentals of Nursing: Concepts, Process and Practice, Pearson Education, →ISBN, page 191:

(pharmacology) Drug that stabilises mood; used often in bipolar disorder.


DDC

(pharmacology) Alternative form of ddC, abbreviation of dideoxycytidine.


capromycin

(pharmacology) Alternative form of capreomycin.


doravirine

From [Term?] + -virine (“nonnucleoside reverse transcriptase inhibitor”).

af

(pharmacology) A reverse transcriptase inhibitor used to treat HIV.


durvalumab

From -l- (“immunomodulating”) + -umab (“human monoclonal antibody”).

(pharmacology) A monoclonal antibody that is an antineoplastic drug


abituzumab

From [Term?] + -tu- (“tumor”) + -zumab (“humanized monoclonal antibody”).

(pharmacology) A humanized monoclonal antibody developed in an attempt to prevent bone lesion metastases in castration-resistant prostate cancer.


anticonstipation

(pharmacology) Preventing or treating constipation.


antiretrovirus

(virology, pharmacology) Countering retroviruses; antiretroviral.


umifenovir

From [Term?] + pheno- + -vir (“antiviral”).

(pharmacology) An antiviral agent that inhibits the fusion of a virus with the host cell.


(pharmacology) An opioid analgesic drug developed in the 1970s and having around 7.5 times the potency of morphine, also used for recreational purposes.


tisagenlecleucel

From tisa- (unique name) + -gen- (“transfer of genetic material (transduced)”) + -lec- (“selection and enrichment manipulation”) + -leu- (“leukocytes”) + -cel (“cellular therapy”).

affix

(pharmacology) An anti-CD19 CAR-T cell therapy used in the treatment of haematological malignancies.


Miltown

en-proper noun

Miltown (countable and uncountable, plural Miltowns)

Bored with the emptiness of her life, she was said to be increasingly turning to the consolations of “mother's little helper”—new lines of tranquilizing drugs, such as Librium and Miltown, meant to soothe the female anxieties that Betty Friedan decried in her bestselling The Feminine Mystique.

2013, Kate Bowler, Blessed: A History of the American Prosperity Gospel, Oxford University Press, →ISBN, page 58:

Hollywood had discovered Miltown — and from then on, the pill became a cultural phenomenon.

2017 August 7, “Miltown: a game-changing drug you've probably never heard of”, in CBC:

There were, of course, ways of obtaining the drug which didn't involve doctors or pharmacies—from private parties to bars selling alcoholic blends such as the ‘Guided Missile’ (a double shot of vodka plus two Miltowns) and the perennially popular ‘Miltini’ (a dry martini with a pill replacing the olive).

2019, Sarah Broughton, Brando's Bride, Parthian Books, →ISBN:

(trademark, pharmacology) The drug meprobamate.


abemaciclib

(pharmacology) An antineoplastic cyclin-dependent kinase inhibitor used to treat breast cancer.


bezlotoxumab

From -tox- (“toxin”) + -umab (“human monoclonal antibody”).

af

(pharmacology) A particular monoclonal antitoxin antibody


danoprevir

From [Term?] + -previr (“hepatitis C virus protease inhibitor”).

(pharmacology) A particular macrocyclic peptidomimetic inhibitor of a protease.


evofosfamide

From [Term?] + -fosfamide (“alkylating agent”).

(pharmacology) A prodrug for the treatment of some cancers.


alitretionin

(organic chemistry, pharmacology) A form of retinoic acid used as dermatological product


-nicline

Nicotinic cholinergic receptor
nicotinic acetylcholine receptor

(pharmacology) Nicotinic cholinergic receptor partial agonist/agonist.


-flurane

general inhalation anesthetic
w:inhalational anesthetic

(pharmacology) Used to form names of halogenated compounds used as general inhalation anesthetics.


-renone

(pharmacology) Used to form names of spironolactone derivatives used as aldosterone antagonists.


-vaptan

(pharmacology) A vasopressin receptor antagonist.


-bradine

(pharmacology) Used to form names of bradycardic agents.


isosorbide dinitrate

(pharmacology) A coronary vasodilator C₆H₈N₂O₈ (trademark Isordil) used especially in the treatment of angina pectoris.


-ritide

From (nat)ri(uretic) + -tide (“peptide, glycopeptide”).

natriuretic peptide
w:natriuretic peptide

(pharmacology) Used to form names of natriuretic peptides.


-sartan

angiotensin II receptor antagonist
w:angiotensin II receptor blocker

(pharmacology) Used to form names of nonpeptidic angiotensin II receptor antagonists used as antihypertensives.


-gliflozin

From gli- (“antihyperglycemic”) + phlo(ri)zin.

sodium glucose cotransporter
w:sodium-glucose transport proteins

(pharmacology) Used to form names of phlorizin derivatives used as sodium glucose cotransporter inhibitors.


-cain-

(pharmacology) A procainamide or lidocaine derivative used as a Class I antiarrhythmic.


galidesivir

From [Term?] + -desi- (“adenosine analog”) + -vir (“antiviral”).

(pharmacology) An antiviral drug that is nucleoside analog.


-arone

(pharmacology) Used to form names of antiarrhythmics.


-alol

(pharmacology) Used to form names of compounds with the structure Ar–CH(OH)CH₂NH–R used as combined alpha and beta blockers.


-ilide

(pharmacology) A sematilide derivative used as a Class III antiarrhythmic.


-tiazem

(pharmacology) Used to form names of diltiazem derivatives used as a calcium channel blockers.


bamlanivimab

bamlani- (unique prefix) + -vi- (“viral”) + -mab (“monoclonal antibody”).

(pharmacology) A neutralising monoclonal antibody directed against the spike protein of SARS-CoV-2.


Librium

Named diazepam and marketed as Valium, this drug is about five times as potent as Librium.

2003, Samuel H. Barondes, chapter 4, in Better than Prozac, Oxford University Press, →ISBN, page 53:

(trademark, pharmacology) The drug chlordiazepoxide.


-thiazide

/ˈθʌɪ.əz.ʌɪd/

(pharmacology) A thiazide derivative used as a diuretic.


-tizide

(pharmacology) A chlorothiazide derivative used as a diuretic.


-poride

sodium–hydrogen antiporter
w:sodium–hydrogen antiporter

(pharmacology) Used to form names of sodium–hydrogen antiporter inhibitors.


DOSS

dioctyl sodium sulfosuccinate
dioctyl sodium sulfosuccinate#English

(pharmacology) Abbreviation of dioctyl sodium sulfosuccinate.


-nidipine

calcium channel blocker
calcium channel blocker#English

(pharmacology) Used to form names of nifedipine derivatives used as calcium channel blockers.


-grel

Probably related to platelet aggregation.

(pharmacology) Used to form names of platelet aggregation inhibitors.


-onidine

(pharmacology) Used to form names of clonidine derivatives used as antihypertensives.


-serpine

(pharmacology) Used to form names of derivatives of Rauwolfia alkaloids.


-dralazine

(pharmacology) Used to form names of hydrazinophthalazine derivatives used as antihypertensives.


-dil

dil- (alternative)
-dil- (alternative)
-dyl (alternative)

(pharmacology) Used to form names of vasodilators.


-pamil

(pharmacology) Used to form names of verapamil derivatives used as calcium channel blockers.


-pril

angiotensin converting enzyme
angiotensin converting enzyme#English

(pharmacology) Used to form names of angiotensin converting enzyme inhibitors.


-prilat

From -pril (“angiotensin-converting enzyme inhibitor”) + -ate (“salt”).

(pharmacology) Used to form names of diacid analogs of angiotensin converting enzyme inhibitors.


-kiren

(pharmacology) Used to form names of renin inhibitors.


-prost-

(pharmacology) Used to form names of prostaglandins.


-profen

(pharmacology) Used to form names of ibuprofen derivatives used as anti-inflammatory agents.


-metacin

(pharmacology) Used to form names of indometacin derivatives used as anti-inflammatory agents.


-clofenac

(pharmacology) Used to form names of ibufenac derivatives used as anti-inflammatory agents.


-zolac

From (pyra)zol(e) + -ac (“acetic acid”).

(pharmacology) Used to form names of anti-inflammatory agents.


-coxib

(pharmacology) Used to form names of selective cyclo-oxygenase inhibitors.


-trexate

(pharmacology) Used to form names of folic acid analogs.


-umab

From hu(man) + -mab (“monoclonal antibody”).

monoclonal antibodies
monoclonal antibody#English

(pharmacology) Used to form names of monoclonal antibodies derived from a human source.

-mab is the base suffix common to all monoclonal antibodies


-c-

(pharmacology) Alternative form of -cir-.


-quine

(pharmacology) Used to form names of quinoline derivatives.


-salazine

From salazo- (“phenylazosalicylic acid derivative”) + -ine.

(pharmacology) Used to form names of phenylazosalicylic acid derivatives.


-sal-

(pharmacology) Used to form names of salicylic acid derivatives.


-nercept

tumor necrosis factor receptor
w:TNF receptor superfamily

(pharmacology) Used to form names of tumor necrosis factor receptor ligands.


-lukast

leukotriene receptor
w:leukotriene receptor

(pharmacology) Used to form names of leukotriene receptor antagonists.


-icase

(pharmacology) Used to form names of uricases.


pneumoprotective

en-adj

pneumoprotective (comparative more pneumoprotective, superlative most pneumoprotective)

more pneumoprotective (comparative)
most pneumoprotective (superlative)

(pharmacology) That serves to protect the lungs.


-semide

(pharmacology) Used to form names of furosemide derivatives used as diuretics.


-rinone

(pharmacology) Used to form names of amrinone derivatives used as cardiac stimulants.


-capone

(pharmacology) Used to form names of catechol-O-methyltransferase inhibitors.


-dopa

(pharmacology) Used to form names of dopamine receptor agonists or dopamine derivatives used as antiparkinsonisms or prolactin inhibitors.


-golide

(pharmacology) Used to form names of ergoline derivatives used as dopamine receptor agonists.


-erg-

(pharmacology) Used to form names of ergot alkaloid derivatives.


-imibe

acyl CoA:cholesterol acyltransferase
w:sterol O-acyltransferase

(pharmacology) Used to form names of acyl CoA:cholesterol acyltransferase inhibitors used as antihyperlipidemics.


-vastatin

Probably from vas- (“vascular”) + -statin.

(pharmacology) Used to form names of HMG-CoA reductase inhibitors used as antihyperlipidemic substances.


-fibrate

w:peroxisome proliferator-activated receptor alpha

(pharmacology) Used to form names of clofibrate derivatives used as peroxisome proliferator-activated receptor alpha agonists.


-barb-

(pharmacology) Used to form names of barbituric acid derivatives used as hypnotics.


thiobutabarbital

From thio- (“containing sulfur”) + secbutabarbital.

af

(pharmacology, veterinary medicine) A short-acting barbiturate derivative (trademark Inactin) which has sedative, anticonvulsant and hypnotic effects and is used in veterinary medicine for induction in surgical anesthesia.


secbutabarbital

(pharmacology) A synthetic barbiturate used especially in the form of its sodium salt C₁₀H₁₅N₂NaO₃ as a sedative and sleep aid.


dil-

-dil- (alternative)
-dil (alternative)
-dyl (alternative)

(pharmacology) Used to form names of vasodilators.


-dil-

dil- (alternative)
-dil (alternative)
-dyl (alternative)


-dilol

From -dil- (“vasodilator”) + -olol (“β-adrenoceptor antagonist”).


-parin

(pharmacology) Used to form names of heparin derivatives including low molecular mass heparins.


-parinux

(pharmacology) Used to form names of synthetic heparinoids.


-arol

(pharmacology) Used to form names of dicoumarol derivatives used as anticoagulants.


-irudin

(pharmacology) Used to form names of hirudin derivatives.


-xaban

(pharmacology) Used to form names of blood coagulation factor Xa inhibitors used as antithrombotics.


-gatran

(pharmacology) Used to form names of thrombin inhibitors used as antithrombotic agents.


-fiban

fibrinogen receptor
w:glycoprotein IIb/IIIa

(pharmacology) Used to form names of fibrinogen receptor antagonists.


-teplase

From Latin tē (“the letter T (for tissue)”) + pl(asminogen) + -ase (“enzyme”).

the letter T (for <i class="Latn mention" lang="en">tissue</i>)

tissue-type plasminogen activator
w:tissue plasminogen activator

(pharmacology) Used to form names of tissue-type plasminogen activators.


protamine sulfate

en-noun

protamine sulfate (countable and uncountable, plural protamine sulfates)

(pharmacology) A mixture of sulfates of protamines obtained from the sperm or testes of fish, which can be used to neutralize the anticoagulant effect of heparin.


-zumab

From -zu- (alteration of humanized) + -mab (“monoclonal antibody”).

af

alteration of <i class="Latn mention" lang="en">humanized</i>

(pharmacology) Used to form names of humanized monoclonal antibodies.


trimethaphan

/tɹaɪˈmɛθ.əˌfæn/

(pharmacology, US) Alternative form of trimetaphan.


trimethaphan camsylate

trimetaphan camsilate
trimetaphan camsilate#English

(pharmacology, US) Alternative form of trimetaphan camsilate.


trimetaphan

(pharmacology) A ganglionic blocking agent used as a salt C₃₂H₄₀N₂O₅S₂ to lower blood pressure especially in hypertensive emergencies.


-tidine

histamine H₂ receptor
w:histamine H2 receptor

(pharmacology) Used to form names of cimetidine derivatives used as histamine H₂ receptor antagonists.


dabigatran etexilate

/dəˌbɪɡ.əˌtɹæn ɪˈtɛk.sɪˌleɪt/

From dabigatran + eth(yl) + (h)ex(oxycarbon)yl + -ate.

(pharmacology) An oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.


guan-

(pharmacology) Used to form names of guanidine derivatives used as antihypertensives.


-peridol

/ˈpɛɹ.ɪˌdɔl/

(pharmacology) Used to form names of haloperidol derivatives used as antipsychotics.


-peridone

(pharmacology) Used to form names of risperidone derivatives used as antipsychotics.


-mantadine

(pharmacology) Used to form names of adamantane derivatives.


-tadine

histamine H₁ receptor
w:histamine H1 receptor

(pharmacology) Used to form names of tricyclic compounds used as histamine H₁ receptor antagonists.


-giline

MAO inhibitor
w:monoamine oxidase inhibitor

(pharmacology) Used to form names of MAO inhibitors type B.


-perone

(pharmacology) Used to form names of 4’-fluoro-4-piperidinobutyrophenone derivatives used as tranquilizers and neuroleptics.


-apine

(pharmacology) Used to form names of psychoactive tricyclic compounds.


-pine

(pharmacology) Used to form names of tricyclic compounds.


-zepine

(pharmacology) Used to form names of tricyclic compounds used as antidepressants/neuroleptics, antiulcers, anticonvulsants, or for hyperthermia.


-piprazole

(pharmacology) Used to form names of phenylpiperazine derivatives used as psychotropics.


-pramine

(pharmacology) Used to form names of substances of the imipramine group.


-oxetine

(pharmacology) Used to form names of fluoxetine derivatives used as serotonin and/or norepinephrine reuptake inhibitors.


-traline

(pharmacology) Used to form names of serotonin reuptake inhibitors.


-steine

(pharmacology) Used to form names of mucolytics other than bromhexine derivatives.


-nakinra

Probably from Ancient Greek (μο)νά(ς) ((mo)ná(s), “solitary, mono-”) + -kinra (“interleukin receptor antagonist”).

interleukin-1 receptor
w:interleukin-1 receptor

(pharmacology) Used to form names of interleukin-1 receptor antagonists.


-kinra

From interleukin receptor + a(ntagonist).

interleukin receptor
w:interleukin receptor

(pharmacology) Used to form names of interleukin receptor antagonists.


-trakinra

/tɹəˈkɪn.ɹə/

From (te)tra- + -kinra (“interleukin receptor antagonist”).

interleukin-4 receptor
w:interleukin-4 receptor

(pharmacology) Used to form names of interleukin-4 receptor antagonists.


trop-

(pharmacology) Used to form names of atropine derivatives.


tetrylammonium

tetrylammonium bromide
tetrylammonium bromide

(pharmacology) The cation tetraethylammonium when used for the drug tetrylammonium bromide.


-curonium

From cur(are) + -onium (“quaternary ammonium compound”).

neuromuscular blocking agent
w:neuromuscular-blocking drug

(pharmacology) Used to form names of neuromuscular blocking agents with rigid structure.