"downregulate" meaning in English

See downregulate in All languages combined, or Wiktionary

Verb

Forms: downregulates [present, singular, third-person], downregulating [participle, present], downregulated [participle, past], downregulated [past]
Etymology: From down- + regulate. Etymology templates: {{prefix|en|down|regulate}} down- + regulate Head templates: {{en-verb}} downregulate (third-person singular simple present downregulates, present participle downregulating, simple past and past participle downregulated)
  1. To decrease the number of cell receptors by using downregulation Derived forms: downregulatable

Inflected forms

{
  "antonyms": [
    {
      "word": "upregulate"
    }
  ],
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "down",
        "3": "regulate"
      },
      "expansion": "down- + regulate",
      "name": "prefix"
    }
  ],
  "etymology_text": "From down- + regulate.",
  "forms": [
    {
      "form": "downregulates",
      "tags": [
        "present",
        "singular",
        "third-person"
      ]
    },
    {
      "form": "downregulating",
      "tags": [
        "participle",
        "present"
      ]
    },
    {
      "form": "downregulated",
      "tags": [
        "participle",
        "past"
      ]
    },
    {
      "form": "downregulated",
      "tags": [
        "past"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "downregulate (third-person singular simple present downregulates, present participle downregulating, simple past and past participle downregulated)",
      "name": "en-verb"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "verb",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English hybridisms",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English terms prefixed with down-",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Pages with 1 entry",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Pages with entries",
          "parents": [],
          "source": "w"
        }
      ],
      "derived": [
        {
          "word": "downregulatable"
        }
      ],
      "glosses": [
        "To decrease the number of cell receptors by using downregulation"
      ],
      "id": "en-downregulate-en-verb--Vn3T0q5",
      "links": [
        [
          "receptor",
          "receptor"
        ],
        [
          "downregulation",
          "downregulation"
        ]
      ]
    }
  ],
  "word": "downregulate"
}
{
  "antonyms": [
    {
      "word": "upregulate"
    }
  ],
  "derived": [
    {
      "word": "downregulatable"
    }
  ],
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "down",
        "3": "regulate"
      },
      "expansion": "down- + regulate",
      "name": "prefix"
    }
  ],
  "etymology_text": "From down- + regulate.",
  "forms": [
    {
      "form": "downregulates",
      "tags": [
        "present",
        "singular",
        "third-person"
      ]
    },
    {
      "form": "downregulating",
      "tags": [
        "participle",
        "present"
      ]
    },
    {
      "form": "downregulated",
      "tags": [
        "participle",
        "past"
      ]
    },
    {
      "form": "downregulated",
      "tags": [
        "past"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "downregulate (third-person singular simple present downregulates, present participle downregulating, simple past and past participle downregulated)",
      "name": "en-verb"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "verb",
  "senses": [
    {
      "categories": [
        "English entries with incorrect language header",
        "English hybridisms",
        "English lemmas",
        "English terms prefixed with down-",
        "English verbs",
        "Pages with 1 entry",
        "Pages with entries"
      ],
      "glosses": [
        "To decrease the number of cell receptors by using downregulation"
      ],
      "links": [
        [
          "receptor",
          "receptor"
        ],
        [
          "downregulation",
          "downregulation"
        ]
      ]
    }
  ],
  "word": "downregulate"
}

Download raw JSONL data for downregulate meaning in English (1.1kB)


This page is a part of the kaikki.org machine-readable English dictionary. This dictionary is based on structured data extracted on 2025-12-23 from the enwiktionary dump dated 2025-12-02 using wiktextract (6fdc867 and 9905b1f). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.

If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.