Southern Comfort

A word of warning: Sugar's expert terrain is like a shot of Southern Comfort — it's gulped quickly and burns on the way down. At Beech, on the other hand, the hard stuff is mellowed into a longer drink. Did I ski Big Boulder? No way.

1989 02, “Skiing”, in (Please provide the book title or journal name), page 99:

What was a knockout, whose sweet-hot drawl hit him like Southern Comfort on an empty belly, doing digging up dirt in a greenhouse in the middle of nowhere? Business, Eric reminded himself, realizing he stared. You're here on business.

1997 January 1, Eve Gaddy, Too Close For Comfort: Lone Star Nights, BelleBooks, →ISBN, page 177:

I paused and let the surrounding environment soak into me like the anticipation of a strong shot off Southern Comfort. You know the way your body stops pumping blood while it waits for that warming pulse to shake through every cell[…]

(Can we date this quote?), M.J. Viskocil, September, Lulu, →ISBN, page 365:

On the sultry, over-amped "Leeds United," she [Amanda Palmer] intones over a slurred, high-stepping horn section: "Who needs love / When there's Southern Comfort?" On this Method-acted album, that's a rhetorical question.

2008 10, “SPIN”, in (Please provide the book title or journal name), page 114:

The compliment spread through me like a shot of Southern Comfort, warming my insides. “But you don't care about that, do you?” he continued. “You only have eyes for Jack.”

2015 May 26, Mary Carter, Accidentally Engaged, Kensington Books, →ISBN:

[...] and suddenly they were kissing, really snogging, and her tongue slid into his mouth like a shot of Southern Comfort, and it was happening,[…]

2015 September 7, Ann Cleeves, Starlings & Other Stories, eBook Partnership, →ISBN:

In Tessa's case, both were the color of Southern Comfort.

2023 April 18, Katherine Heiny, Games and Rituals: Stories, Penguin, →ISBN:

An American fruit-flavored whiskey liqueur, created in New Orleans in 1874, which is caramel in color.


sulfathalidine

The bowel is prepared preoperatively with neomycin and sulfathalidine. A wide transverse lower abdominal incision is used.

1954 February 15, Oswald S. Lowsley, Thomas H. Johnson, Antonio E. Rueda, “Operation for Urinary Diversion”, in Modern Medicine, volume 22, number 4, Minneapolis, Minn.: Modern Medicine Publications, Inc., page 89:

(pharmacology, dated) Synonym of phthalylsulfathiazole.


hydrosulphosol

A former trademark of E. C. Lientz & Co., Inc.

Hydrosulfosol in oil with gentle pressure dressings may promote healing after severe burns of the eye. For conjunctival and corneal burns, 0.5% cortisone is used locally on dressings and, after the dressings are omitted, four times daily.

1954 February 15, William B. Clark, Edwin B. Dunphy, S. Rodman Irvine, Lawrence T. Post, Derrick T. Vail, “Early Treatment of Eye Injury”, in Modern Medicine, volume 22, number 4, Minneapolis, Minn.: Modern Medicine Publications, Inc., page 146:

(pharmacology, dated) Synonym of calsulfhydryl.


calsulfhydryl

Since 1942 several clinical investigations have been published describing the increased healing rate of corneal wounds treated with calsulfhydryl (Hydrosulphosol¹). […] The present study was undertaken therefore to evaluate the effect of calsulfhydryl on a controlled series of rabbits corneas injured by abrasion or by acid or alkali burns.

1953 December, Robert E. Rocknem, “Evaluation of wounds of the rabbit cornea treated with calsulfhydryl (Hydrosulphosol)”, in Archives of Ophthalmology, volume 50, number 6, →DOI, page 696:

(pharmacology, dated) A glycerol–water solution containing calcium polysulfides and calcium thiosulfates, formerly used for the treatment of chemical burns of the eye and other conditions.


residual alkalinity

(chemistry) The remaining alkalinity in water after a reaction or process has occurred; the capacity of a specific portion of water to resist changes in pH when acids or bases are added.


lager-conditioned

Of beer, produced using the bottom fermentation process.


dry-hopped

en-adj

dry-hopped (comparative more dry-hopped, superlative most dry-hopped)

more dry-hopped (comparative)
most dry-hopped (superlative)

Of beer, having had hops added directly added while fermenting.


PTMI

(toxicology) Initialism of provisional tolerable monthly intake.


PTWI

(toxicology) Initialism of provisional tolerable weekly intake.


PTDI

(toxicology) Initialism of provisional tolerable daily intake.


TWI

Coordinate term: TDI

In May 2001 an expert committee has decided that tolerable doses should be expressed as tolerable weekly intake (TWI) and established TWI = 14 pg/kg.

2005, Przemysław Mastalerz, The True Story of DDT, PCB, and Dioxin, Wydawnictwo Chemiczne, →ISBN, page 91:

tolerable weekly intake
w:tolerable weekly intake

(toxicology) Initialism of tolerable weekly intake.


drug holiday

(pharmacology) A time period when a patient ceases taking medication.


Wildnil

(organic chemistry, pharmacology) Synonym of carfentanil (trade name)


(organic chemistry, pharmacology) Synonym of carfentanil


nippitaty

(obsolete) Peculiarly strong and pleasant alcoholic drink.


phenibut

(recreational drugs) β-phenyl-GABA, a gabapentinoid drug similar to baclofen and gabapentin, often legally sold online and taken orally for its euphoric effects.


mife

The miso/mife combination is becoming increasingly popular: In 2011, it accounted for 36 percent of all abortions before nine weeks of gestation, and it’s often considered the gold standard of medication abortion, with an estimated success rate that is nearly 10 percent higher than using miso alone (92 to 95 percent and 80 to 85 percent, respectively).

2014 June 27, Erica Hellerstein, “The Rise of the DIY Abortion in Texas”, in The Atlantic:

(pharmacology, informal) Clipping of mifepristone.


norclobazam

(pharmacology) A metabolite of clobazam in which a methyl group has been removed from a nitrogen atom. IUPAC name is 7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione.


firsocostat

(pharmacology) An acetyl-CoA carboxylase inhibitor drug.


penicillin VK

(pharmacology) Synonym of phenoxymethylpenicillin.


mirikizumab

A monoclonal antibody used to treat ulcerative colitis.


free run

(winemaking) Unfermented or only partially-fermented juice, derived from grapes that have been crushed but not yet pressed; the must that runs off freely without pressure.


iberdomide

Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).

2022 March 17, Joan T. Merrill, Victoria P. Werth, Richard Furie et al., “Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus”, in The New England Journal of Medicine, volume 386, number 11, →DOI, page 1034:

systemic lupus erythematosus
systemic lupus erythematosus

(pharmacology) A derivative of thalidomide used experimentally for the treatment of multiple myeloma and systemic lupus erythematosus.


repotrectinib

An anticancer medication used to treat non-small cell lung cancer.


HHCH

Japanese: HHCH (HHCH) (hexahydrocannabihexol)

(organic chemistry, pharmacology) Initialism of hexahydrocannabihexol.


iptacopan

(organic chemistry, pharmacology) A medication used to treat paroxysmal nocturnal hemoglobinuria.


t.i.d.

en-adv

t.i.d. (comparative more t.i.d., superlative most t.i.d.)

more t.i.d. (comparative)
most t.i.d. (superlative)

(medicine, pharmacology) Three times a day


b.i.d.

b.i.d. (comparative more b.i.d., superlative most b.i.d.)

more b.i.d. (comparative)
most b.i.d. (superlative)


café royale

Pseudo-Gallicism (formed within English), from café (“coffee”), with postpositive (as usual in French) royale f, royal m (“royal”). Although café is masculine, the feminine form royale is used.

Café royale was also a favourite beverage with them—a cup of strong black coffee with brandy, the latter being bought separate in a bottle. The coffee could be doctored to any degree of strength. At first, my shipmates would take one portion of brandy, a swallow of café royale, and in would go another, and so it continued until each bottle was emptied.

1902, Stanley Waterloo (indicated as editor), “A Glimpse of the Mediterranean”, in The Story of a Strange Career, Being the Autobiography of a Convict: An Authentic Document, New York, N.Y.: D. Appleton and Company, pages 145–146:

We had a café royale—with Lanagan pouring his thimble-full of cognac in my glass—and Morton left.

1913, Edward H. Hurlbut, “The Conspiracy of One”, in Lanagan, Amateur Detective, New York, N.Y.: Sturgis & Walton Company, page 73:

“I’ve got a little real good brandy in my tent. Like to drop over and have a café royale?”

1928 May 15, Thomson Burtis, “Misfortune Hunters: A New Novelette of the Border Air Patrol”, in Anthony M[elville] Rud, editor, Adventure, volume LXVI, number 5, New York, N.Y.: The Butterick Publishing Company, page 174, column 2:

Sherry before dinner—when in her fury she had thought it impossible to face her mother’s stupid guests—and a cognac after dinner to satisfy Peter Knorr’s whimsy for a café royale had fanned Hope Borden’s smoldering anger against that intolerably rude boy downstairs.

1934 October, Beatrice Blackmar, “Charity Ball”, in H[arry] P[ayne] Burton, editor, Hearst’s International Combined with Cosmopolitan, volume XCVII, number 4, New York, N.Y.: International Magazine Company, Inc., page 158, column 1:

He followed this with a thick and tender small steak, soufflé potatoes, asparagus hollandaise, a tossed green salad and zabaglione, along with a café royale for a finisher.

1951 September, Sam Merwin, Jr., “House of Many Worlds”, in Startling Stories, volume 24, number 1, Kokomo, Ind.: Better Publications, Inc., section XI, page 62, column 2:

I took her coat, built up the fire, and fixed her a café royale while she stood in front of the fire.

1952, Peter Ordway, The Face in the Shadows, New York, N.Y.: A[aron] A. Wyn, Inc., →LCCN, page 189:

There was alwavs steady drinking, in the middle of the night should he awaken, before breakfast, and during it, when he turned his coffee into a café royale with brandy, at lunchtime and at the cocktail hour, and of course, a nightcap.

1956 January, Virginia Conroy, “I Am the Widow of an Alcoholic”, in Today’s Health, volume 34, number 1, Chicago, Ill.: American Medical Association, pages 56–57:

Burning with a gem-like flame in a spoon warmed by the hot coffee, a cube of sugar is set ablaze with cognac to make a café royale.

1956 March, Poppy Cannon, “Cognac: Grand finale for a perfect dinner—Overture to a memory-full evening”, in House Beautiful, volume 98, number 3, New York, N.Y.: Hearst Corporation, page 116:

After-dinner demitasse cups of coffee can be great fun, either a café brûlot or a café royale. Café royale is so simple that it really doesn’t require a recipe. Just place a lump of sugar in a teaspoon of cognac, ignite the cognac over a demitasse cup of coffee, and then lower the spoon slowly into the cup.

1961, Julie Benell, “Be daring: flaming cookery”, in Let’s Eat at Home, New York, N.Y.: Thomas Y. Crowell Company, →LCCN, page 369:

He was at a banquette in the Stag Bar, with a café royale and sixteen registration cards, when a man who looked like a shy Milquetoast, a bookkeeper with an inferiority complex, deposited his brief case on the leather cushion beside the Marshal.

1961, Stewart Sterling [pseudonym; Prentice Winchell], chapter 12, in Too Hot to Handle: A Marshal Pedley Novel, New York, N.Y.: Random House, page 77:

He watched her as she took a sip of the steaming coffee, wondering how long she had been in the kitchen, how many cups of café royale she had had already.

1964, Borden Deal, The Loser, Garden City, N.Y.: Doubleday & Company, Inc., →LCCN, page 57:

Anne ordered a café royale while Peter had hot chocolate with brandy.

1968, James Kerr [pseudonym; Frederick Mugler], The Clinic, New York, N.Y.: Coward-McCann, Inc., pages 71–72:

Tiny cups of café royale were served in the carpeted parlor after dinner, with the wonder of an infinitesimal silver spoon on each saucer!

1969, Nell Wilson Parsons, chapter 22, in Upon a Sagebrush Harp, Saskatoon, Sask.: Prairie Books, The Western Producer, page 122:

(His father has since discovered that brandy and medicine mix just fine, and at 81 he will not turn down a café royale.)

1973 February 19, “Gin Rummy and Racing Cars”, in Sports Illustrated, volume 38, number 7, Chicago, Ill.: Time Inc., page 33, column 1:

Special dishes like prawns, salami, asparagus, and dry-cured hams are served with all the lamb one can eat, topped off with café royale and singing.

2009, Joxe Mallea-Olaetxe, The Basques of Reno and the Northeastern Sierra (Images of America), Charleston, S.C.: Arcadia Publishing, →ISBN, page 82:

(uncountable) Coffee with brandy, sometimes served with spices, cream, etc.; (countable) a serving of this beverage.


peppermintini

LL-Q1860 (eng)-Flame, not lame-peppermintini.wav

A kind of martini cocktail made with peppermint.


enzybiotic

(pharmacology) An experimental enzyme used in antibacterial therapy.


scaghead

The Breeding Ground website message board has been a-buzz with accusations, counter-accusations & general slanging after the previous live encounter. Hooper are scagheads & Pocket Venus are crap tradesmen. For the internet lurker its been an entertaining read & great publicity for the bands.

2002 May 11, “FUDGED NOVELLO NUTONIC – Breeding Ground, Rhyl”, in link2wales and Liverpool – Crud Gig Review – Crud Fanzines PLC present …:

she is young and i'm sure when she was at school there was a lot of education on drugs (my daughters been having it in yr 7!!) They use scare mongering tactics of showing young pretty girls turning into toothless scagheads!

2008 January 26, sammyg, “Amy Winehouse - Loser or Legend??”, in BritishExpats.com, archived from the original on 2024-01-07:

Newspaper readers will weep over the death of a pop idol through drugs; a politician will be praised for his ‘brave struggle’ against alcohol. In popular culture – films, books and television – we have come to expect our flawed heroes often to have an addiction problem as one of their flaws, a lonewolf cop bucking the rules and knocking back malt whisky while meditating on a case, a singer in rehab, a public figure making public penance.
Less favourably are seen the ‘scagheads’, the ‘junkies’, the street addicts, the working class addicts. Although victims all their lives of unequal and unjust social conditions, turning to drugs or drink or gambling to escape if only for a moment, it is they who are most harshly blamed and despised for their lack of responsibility – while those with a lifetime of advantages are treated with adulation and sympathy.

2017 October 16, Zero52, “Addiction and Personal Responsibility”, in The Machine Zone [“two volunteers, both with experience of extreme addiction”]:

Imagine having London dungeons but, Manchester edition! Scagheads popping out on you in the dark, the lot!

2023 January 17, A-undecisiveOpinion, “Seems legit”, in r/manchester:

It's to stop skagheads and prostitution. As well as cutting cost on paying for maintenance and cleaning

2024 June 1, AdministrativeShip2, “Local councils remove public toilets so they can fine drunk people for public urination and make money”, in r/LowStakesConspiracies:


dumpster juice

en-noun

dumpster juice (usually uncountable, plural dumpster juices)

LL-Q1860 (eng)-Flame, not lame-dumpster juice.wav


goofy juice

LL-Q1860 (eng)-Flame, not lame-goofy juice.wav

(psychiatry, humorous) A liquid medication once used to tranquilize psychiatric patients.

A cocktail consisting of everclear alcohol and various fruits.


bay breeze

LL-Q1860 (eng)-Flame, not lame-bay breeze.wav

A cocktail which has a Cape Codder as its base, with the addition of pineapple juice.


ADDO

Accredited Drug Dispensing Outlet#English

(Tanzania, pharmacy) Initialism of Accredited Drug Dispensing Outlet.


median lethal time

median lethal time (usually uncountable, plural median lethal times)

(toxicology) The average time interval during which 50% of a given population may be expected to die following the administration of a chemical or physical agent at a given concentration.


strawberrita

LL-Q1860 (eng)-Flame, not lame-strawberrita.wav

And they come in five fantastic flavors: Torada Original, Strawberrita, Melonrita, and two totally new ones : Cinnamonrita “The Original Cinnamon Margarita' and Salsarita “The Original Salsa Margarita'.

1981, Market Watch, volume 13, M. Shanken Communications, page 83:

Less romantic, I suggest, is the strip joint of the Riverside Lounge which offers 'girls, girls, girls' and 'Limearita' and 'Strawberrita' to drink; I didn't stop.

2014 July 17, Mark Avery, A Message from Martha: The Extinction of the Passenger Pigeon and Its Relevance Today, A&C Black, →ISBN:

He and his girlfriend spent all their time working. She was studying to be a lawyer. They had no reason to throw their life away on Strawberrita.

2017 October 12, Elle Truth, Invisible Generation: The Saga of the Domestic Engineer in High Society Homes, Xlibris Corporation, →ISBN:

You can hear the deputy ask the driver, Darrol Austin Luce if he’s been drinking. “You been drinking a little bit?” “No, I haven’t been drinking at all, but there is a strawberrita in there,” said Luce. The 19-year-old driver admitted there’s alcohol in the car but maintained he had not been drinking.

2018 August 10, Andy Cordan, “2 teens arrested after drug bust in Lawrence Co.”, in WKRN, archived from the original on 2021-03-03:

The guacamole at Angela’s is the real deal, and if you’re in need of a great margarita, the restaurant has a number of options, ranging from the classic version to a mangorita, coconutrita, and strawberrita.

2019 May 17, Erin Kuschner, “Discover a global dining scene in East Boston”, in Boston.com, archived from the original on 2022-01-21:

It wouldn’t be a true Happy Hour without some delicious drinks to complement the Border Style Mex. For $3, guests can raise their glasses with any of these refreshing beverages – select grande domestic drafts, Dos Equis draft, Corona and Dos Equis bottles or regular House Margarita. For an additional $1, upgrade to a grande Dos Equis draft or a grande House Margarita or try a grande Strawberrita or grande Mango Tango for $5.

2020 July 21, Cami Studebaker, “On The Border Livens Up Happy Hour with Bold New Specials”, in RestaurantNews.com, archived from the original on 2021-02-05:

If you're looking for something frozen the also serve a frozen margarita as well as a frozen "strawberrita."

2022 January 26, Eddie Ritz, “Love tacos? This new Mexican restaurant at Delray Marketplace has you covered!”, in Palm Beach Post, archived from the original on 2023-03-18:

Featured drinks include the Blue Riptide fish bowl and portable summer cooler bags with flavors of Strawberrita, White Lightning and Henny Raz. Along the Cedar Point Boardwalk, the mobile Boardwalk Beer Bike will serve a variety of beers and seltzers.

2022 July 26, Crawford County Now Staff, “Cedar Point Nights returns to the Cedar Point Beach”, in CrawfordCountyNow.com, archived from the original on 2022-07-27:

A strawberry flavored margarita cocktail.


percy

Them percies fuck up my reaction
She stuck on me she immune

2018 August 17, “Choose” (track 8, 0:49 from the start), in Summrs (lyrics), Devotion:

Yeah, I just do it (Yeah), I don't hesitate (No)
I took a couple percies, yeah, to the face

2021 June 6, “Come Again” (0:44 from the start), Yeat (lyrics):

Why did you desert me?
You keep poppin percies

2022 September 22, “Unworthy” (track 12), in Superstar:

It's too much hate and envy
My nigga change my percies

2022 December 20, “Petty” (track 7), in MoneySign Suede (lyrics), Parkside Santa:


cold duck

Calque of German kalte Ente, from kalten Ende (“cold end”). Attested in English from the 1960s, see quotations below.

I would like to give Cold Duck a special mention because it was discovered by me personally—along with some two million Detroiters who at that time were the only Americans who’d ever heard of or enjoyed it.

1966, Wines and Vines, volume 47, page 43:

Many young or new to the industry at last week’s party may have wondered what it was all about — the Beatles songs, the bright-eyed dancers, the re-introduction of a sparkling red wine called Cold Duck.

1997 June 22, Michale Brett, “Montana celebrations with Beatles and Cold Duck”, in Sunday Star-Times, Wellington, New Zealand, page E 10:

“My family drank cold duck every Thanksgiving and, being a kid, I loved it. It was so sweet, so cheap, the kind of thing a kid could love,” she said.

2004 December 1, Virginie Boone, quoting Karen MacNeil, “Celebrate red: beyond the horror that was cold duck”, in Press Democrat, Santa Rosa, California, page D1:

Thank you, Rosie, I now have a lovely image of your husband arriving at the Pearly Gates, with his swinging Safari Suit tucked under one arm, and a bottle of Cold Duck under the other, asking where the Fondue Party is.

2023 June 24, “Many of you wrote to me with your own tales of domestic crimes”, in The Mercury, Hobart, Tasmania, page 4:

A sparkling red wine, often made by blending champagne with red wine, sometimes with additional flavorings added.


snicker licker

LL-Q1860 (eng)-Flame, not lame-snicker licker.wav

A martini made with vodka, Irish cream, and crème de cacao.


Placidyl

Placidyl (countable and uncountable, plural Placidyls)

Marketing name, apparently from placid + -yl.

His horror of insomnia, compounded with a family history of compulsive worrying, caused him to down three or four Placidyls, Seconals, Quaaludes, or Tuinals almost every night—and often it was a combination of all four.

1985, Priscilla Presley, Sandra Harmon, Elvis and Me, Putnam, →ISBN, page 151:

(pharmacology) Trade name of ethchlorvynol, a sedative.


parent drug

(pharmacology) The initial compound in a biotransformation reaction, requiring metabolism for activation.


Evzio

(pharmacology) An opioid antagonist indicated for the emergency treatment of a known or suspected opioid overdose.


Nyxoid

(pharmacology) A single-dose nasal spray used for the emergency treatment of an opioid overdose.


α-Methylfentanyl

(pharmacology, drugs) An opioid analgesic that is an analog of fentanyl.


vadadustat

(organic chemistry, pharmacology) A drug used to treat symptomatic anemia associated with chronic kidney disease.


Opimian

en-adj

Opimian (comparative more Opimian, superlative most Opimian)

more Opimian (comparative)
most Opimian (superlative)

From the name of the Roman consul Lucius Opimius.

(wine) Of or relating to the famous Roman vintage of 121 BC.


needle beer

en-noun

needle beer (countable and uncountable, plural needle beers)

So called because a needle could be used to inject alcohol into the cask.

Alcoholic beer made illicitly by adding alcohol to near beer.


legal high

A substance that has similar effects to an illegal drug but is not itself illegal.


LASA

(pharmacology) Initialism of look alike sound alike. (referring to pharmaceuticals that are visually similar in physical appearance or packaging and similar in their names, orthographies, or phonetics).


isoxepac

non-steroidal anti-inflammatory drug
non-steroidal anti-inflammatory drug

(pharmacology) A non-steroidal anti-inflammatory drug with analgesic activity. It is also used as an intermediate in the synthesis of olopatadine hydrochloride.


amenamevir

Amenamevir … exerts antiviral action by inhibiting the enzymatic activity of a virus-derived helicase.

2019, Maeda H, Nakamura H, Kikukawa Y. Pharmacological profiles and clinical effects of amenamevir tablet as treatments for herpes zoster. Nihon Yakurigaku zasshi. Folia Pharmacologica Japonica. Volume 153(1). PMID: 30643090. pages 35-43

(pharmacology) An oxadiazole phenyl derivative, an antiherpes agent that does not have a nucleic acid-like structure.


duoperone

(pharmacology) A phenothiazine, C₂₈H₂₆F₄N₂OS with neuroleptic and antiemetic properties. It has a prolonged duration of action.


dosmalfate

Dosmalfate … has been developed and marketed in some countries for therapeutic use in the healing of gastric and duodenal ulcers.

2003, Isabel Villegas, Carmen La Casa, Aurelio Orjales, Catalina Alarcón de la Lastra. Effects of dosmalfate, a new cytoprotective agent, on acute and chronic trinitrobenzene sulphonic acid-induced colitis in rats. European Journal of Pharmacology. Volume 460(2-3). page 210

(pharmacology) A diosmin heptakis (hydrogen sulfate) aluminium complex, a non-systemic cytoprotective drug.


FGA

Coordinate term: SGA

first-generation antipsychotic
w:typical antipsychotic

(pharmacology) Initialism of first-generation antipsychotic.


underbrewer

LL-Q1860 (eng)-Flame, not lame-underbrewer.wav

In 1930 de Bavay resigned as brewer manager. Carl Stefanson, the under-brewer, took his place.

1987, Keith Dunstan, The Amber Nectar, Ringwood: Vicking O'Neil, page 86:

An apprentice brewer learning the brewing craft and trade from a chief brewer.


booze baron

(US) A person who organised the illegal production and sale of alcohol during a Prohibition.


popper up

en-verb

popper up (third-person singular simple present poppers up, present participle poppering up, simple past and past participle poppered up)

poppers up (present singular third-person)
poppering up (participle present)
poppered up (participle past)
poppered up (past)

(slang, informal, transitive) To administer or intoxicate with amyl nitrite, a recreational drug.


cyclohexyloxycarbonyloxyethyl

/ˌsaɪkləʊˌhɛksɪlˌɒksɪkˌɑːbənɪlˌɒksiˈɛθɪl/

/ˌsaɪkləʊˌhɛksɪlˌɒksiˌkɑːbənɪlˌɒksiˈɛθɪl/

From cyclohexyl + oxy + carbonyl + oxy + ethyl.

compound

(pharmacology) The ester in which prodrug form candesartan is prepared for administration in order to increase its bioavailability.


biobetter

From bio- + better. Coined by Indian business executive G. V. Prasad, managing director of Dr. Reddy's Laboratories, in 2007.

coinage

Coordinate term: biosimilar

In general, originators have short-term options available, such as patent litigation, but should focus on sustainable long-term strategies such as development of biobetters or incorporating biosimilars as complements to existing products.

2016 February, Daniel Casey, “Key strategic factors for stakeholders in the current global biosimilar market”, in Drug Discovery Today, volume 21, number 2, →DOI, page 208:

(pharmacology) A medication developed by modifying an approved biological drug to enhance its properties (e.g., improved efficacy, higher selectivity or lower toxicity).


time of origin

en-noun

time of origin (countable and uncountable, plural times of origin)

(wine) The age or oldness of a wine; vintage.


oatmeal cookie

LL-Q1860 (eng)-Flame, not lame-oatmeal cookie.wav

(cocktails) A cocktail consisting of Irish cream, Goldschläger, and butterscotch schnapps.


proemetic

en-adj

proemetic (comparative more proemetic, superlative most proemetic)

more proemetic (comparative)
most proemetic (superlative)

(pharmacology) That induces emesis (vomiting).


proemetic

(pharmacology) An agent that induces emesis (vomiting).


ceiling effect

(pharmacology) The process of increasing doses of a given medication to have progressively smaller incremental effect.


time delay toxin activation

(oncology, pharmacology) A process for producing a class of chemotherapy drugs which can be administered in a nontoxic form and, subsequent to a time delay, allows for a differential concentration in the target cancer or invasive tissues or cells, minimizing the toxicity to healthy cells, thereby reducing the adverse side effects of chemotherapy.


Eagle effect

Named after Harry Eagle who first described it.

(microbiology, pharmacology) A phenomenon observed in which higher concentrations of antibiotics paradoxically improve bacterial survival.


merisa

From Juba Arabic meriisa, from Sudanese Arabic مريسة (marīsa).

Many of the Sudan women earned cash by making the local merisa beer, weaving mats and rugs and tanning skins for sale in the local markets.

1975, United Nations. Economic Commission for Africa, Employment of Women in the Sudan: Paper:

a form of millet beer popular in South Sudan


tarlatamab

A drug used to treat small-cell lung cancer.


candy flip

(slang) A combination of the drugs LSD and MDMA.


Benadryl

en-noun

Benadryl (countable and uncountable, plural Benadryls)

The “Benadryl challenge”, wherein participants took a large amount of antihistamines in an attempt to produce hallucinogenic effects, led to at least one death.

2022 October 30, Kari Paul, “What TikTok does to your mental health: ‘It’s embarrassing we know so little’”, in The Guardian, →ISSN:

Reading his posts as posted, sitting in my NOBE studio, railing Benadryls, getting progressively less attractive to ex bae due to domestic overexposure, I was rapt.

2022, Sean Thor Conroe, Fuccboi, Hachette, →ISBN:

The Benadryl was for sleep, not allergies. I'd been having this thing where I woke up every night at two a.m.

2024, Miranda July, All Fours, Canongate Books, →ISBN:

An antihistamine medication used to stop allergies or as a sleep aid.


pamoic

(chemistry, pharmacology) Of or relating to pamaquine.


GnT

Alternative form: G&T

In a state of barely controlled desperation, we cobbled together what we had: a dribble of Campari, a shot of gin and the dregs of a bottle of tonic. […] The resulting cocktail, effectively a campari and orange mixed with a GnT, has become our signature drink.

2022, Paul Cassidy, Got Beethoven: My First Forty Years with the Brodsky Quartet, Market Harborough: Troubador Publishing Ltd, pages 102–103:


crack kills

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(slang, sarcastic, humorous) Used to warn others of the dangers of crack cocaine and drugs in general.


Turbo Diesel

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A cocktail consisting of snakebite and black and vodka.


lowball glass

Coordinate term: highball glass

A short glass tumbler used for serving lowballs, usually holding 180–300 ml.


SSZ

(pharmacology) Abbreviation of sulfasalazine.


salazopyrin

Modern drug treatment with salazopyrin is very effective and will usually control the symptoms. If the disease proves severe, the colon or a portion of it can be removed.

1987, “Colon and colitis”, in Trevor Weston, editor, The Complete Illustrated Book of Family Health, Toronto: York Press, →ISBN, page 93:

(pharmacology) Synonym of sulfasalazine.


KJ

KJ (countable and uncountable, plural KJs)

Probably an initialism of crystal (“phencyclidine”) + joint (“marijuana cigarette”).

This was some other shit, what they smoked, could have been fucking angel dust sprinkled on, they called that KJ. Shit, knowing them that’s exactly why I couldn’t stop my head from bobbing, and why the streetlights were so fucking bright, and mean seeming, and, like, too red. I was glad I only hit it once.

2018, Tommy Orange, “Calvin Jonhson”, in There There, New York, N.Y.: Vintage Books, →ISBN, page 92:

(slang, US) Phencyclidine (PCP); also, a marijuana cigarette laced with phencyclidine.


regular insulin

regular insulin (countable and uncountable, plural regular insulins)

(medicine, pharmacology) A type of short-acting medical insulin.


Blood and Sand

A mixed drink served in a champagne coupe, whose ingredients include blood orange juice, sweet vermouth, Cherry Heering and scotch.


combination drug

combination drug (plural combination drugs)

(pharmacology) A medicine that includes two or more active ingredients combined in a single dosage form.


Subutex

Marketing coinage, perhaps based on sublingual (“administered through placement under the tongue”).

He was a Subutex addict. Subutex is supposedly used to wean people off heroin but, from what I have seen, there are more Subutex addicts in jail than there are heroin addicts (and there are a lot of heroin addicts).

2010, Simon Eddisbury, Lowlife, London: John Blake, →ISBN, page 22:

She'd seen a doctor who’d prescribed Subutex, a drug-replacement treatment designed to wean the user off heroin. It had made her throw up. I was so relieved and told her how proud I was of her for taking control.

2013, Mitch Winehouse, Amy, My Daughter, London: Harper, →ISBN, page 120:

(pharmacology) A (now discontinued) brand name for buprenorphine, used to treat opiate addictions.


controlled-release

(pharmacology) Of a drug or medicine, involving the gradual release of an active component.


devil's cut

For quotations using this term, see Citations:devil's cut.

(uncommon) The portion of a distilled alcoholic spirit's volume that is lost by being absorbed into the wood of the barrels it matures in.


septagliptin

dipeptidyl peptidase-4
dipeptidyl peptidase-4

(pharmacology) A dipeptidyl peptidase-4 inhibitor used as a drug to treat diabetes


glifozin

(pharmacology) A sodium-glucose co-transporter-2 (SGLT2) inhibitor used to treat type-2 diabetes.


Halcion

Halcion (countable and uncountable, plural Halcions)

[…]I'm experiencing a major-league anxiety attack, searching my pockets for Valium, Xanax, a leftover Halcion, anything, and all I find are three faded Nuprin in a Gucci pill-box, so I pop all three into my mouth and swallow them down with a Diet Pepsi and I couldn’t tell you where it came from if my life depended on it.

1991, Bret Easton Ellis, American Psycho, London: Picador, →ISBN, page 148:

(pharmacology) Brand name for triazolam.


Nuprin

Nuprin (countable and uncountable, plural Nuprins or Nuprin)

(pharmacology) Brand name for ibuprofen.


Blue Russian

A cocktail containing vodka and blue curaçao.


English whisky

English whisky (plural English whiskies)

English whisky (whiskey) is a liquor made from cereal grains, malt and water. This includes malt whisky and grain whisky.


xevinapant

(pharmacology) A drug candidate targeting head and neck cancer.


seladelpar

A drug used to treat primary biliary cholangitis.


crovalimab

A monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria.


nemolizumab

A monoclonal antibody used to treat prurigo nodularis.


palopegteriparatide

A hormone replacement therapy used to treat hypoparathyroidism.


ensifentrine

A drug used to treat chronic obstructive pulmonary disease.


axatilimab

chronic graft-versus-host disease
chronic graft-versus-host disease

A monoclonal antibody used to treat chronic graft-versus-host disease.


vorasidenib

A drug used to treat certain forms of glioma.


imetelstat

A drug used to treat myelodysplastic syndromes with transfusion-dependent anemia.


abortifactive

[…] abortifactive agents such as Brucella abortus and Tritrichomonas foetus are not present in the Swedish bovine population […]

2003, Susanne Stenlund, Hans Kindahl, Arvid Uggla, Camilla Björkman, “A Long-Term Study of Neospora caninum Infection in a Swedish Dairy Herd”, in Acta Veterinaria Scandinavica, volume 44, number 2, pages 63-71:

Complete necropsies, abortion panels to rule out other abortifactive agents, serum Ig levels, and aoEBA-specific immunohistochemistry (IHC) were performed on each fetus to confirm EBA diagnosis.

2011, Roxann S. Brooks, Myra T. Blanchard, Mark L. Anderson, Mark R. Hall, Jeffery L. Stott, “Quantitative duplex TaqMan real-time polymerase chain reaction for the assessment of the etiologic agent of epizootic bovine abortion”, in Journal of Veterinary Diagnostic Investigation, volume 23, number 6, pages 1153-1159:

[…] a high degree of seropositivity to N. caninum was diagnosed after evaluating for various abortifactive agents.

2015, Priya Bapodra, Barbara A Wolfe, “Investigation of Neospora caninum seroprevalence and potential impact on reproductive success in semi-freeranging Père David’s deer (Elaphurus davidianus)”, in Veterinary Record Open, volume 2, number 1:

Abortion panels were conducted to identify fetal/neonatal losses due to other abortifactive agents.

2022, Myra T. Blanchard, Mike B. Teglas, Mark L. Anderson, Peter F. Moore, Bret R. McNabb, Kassidy M. Collins, Bret V. Yeargan, Jeffrey L. Stott, “Protection of Cattle against Epizootic Bovine Abortion (EBA) Using a Live Pajaroellobacter abortibovis Vaccine”, in Vaccines (Basel), volume 10, number 2, page 335:

REMINDER: Steroids may be abortifactive for gravid females; be willing to live by the consequences. Use only in life threatening circumstances for pregnant females.

2024, “Chemical Immobilization, Capture and Handling:”, in Yellowstone Grizzly Project, archived from the original on 2024-08-26:

(pharmacology) Inducing abortion or miscarriage, abortifacient.


lazertinib

A drug used to treat non-small cell lung cancer.


angiotensin receptor blocker

angiotensin receptor blocker (plural angiotensin receptor blockers)

renin-angiotensin system
renin-angiotensin system

(medicine, pharmacology) A type of pharmaceutical that binds to and inhibits AT1 and thereby blocks the arteriolar contraction and sodium retention effects of the renin-angiotensin system.


-dronic

From etidronic acid, itself from et(hyl) + (h)ydr(oxy-) + (di-) + (phosph)onic.

af

(pharmacology, organic chemistry) describes derivatives of etidronic acid, used as calcium metabolism regulators


-antel

From anthelmintic (“against parasitic worms”), with simplification of the -nth- and truncation.

(pharmacology) Forms names of anti-worm drugs, often pyrantel derivatives.


benz

Clipping of benzedrine, originally a brand name for amphetamine. Possibly influenced by Benz (short for Mercedes-Benz), alluding to its high speed.

Now from taking all this Benz and scrumpy and stuff, I wasn’t all that bright on remembering where I had been and what I was doing most of the time, and even when people spoke to me it took me about two minutes to register what they had said.

1961, Frank Norman, “A Parrot, a Juke-box and the Benz” (chapter 3), in Stand on Me: A true story of Soho with a glossary of slang, for those who need it, New York, N.Y.: Simon and Schuster, Inc., →LCCN, page 30:

(slang) The drug amphetamine, used recreationally for its stimulant effects.


robustoxin

Derived from the species name Atrax robusta + toxin

Sydney funnel-web spider
Sydney funnel-web spider

(toxicology) The lethal toxin from the Sydney funnel-web spider.


atracotoxin

Derived from Atrax, the genus of the spider, + -o- + toxin

(toxicology) A toxin from the Sydney funnel-web spider.


robustotoxin

Derived from the species name Atrax robusta + -o- + toxin

(toxicology) Alternative spelling of robustoxin


cypro

(pharmacology, informal) Clipping of cyproterone.


levacetylleucine

Niemann-Pick disease
Niemann-Pick disease

(pharmacology) A drug for the treatment of neurological manifestations of Niemann-Pick disease type C.


glasdegib

(pharmacology) A drug targeting the smoothened protein of the hedgehog signaling pathway, used for the treatment of acute myeloid leukemia.


Porto flip

A cocktail made from brandy, port wine, and egg yolk.


malt beer

A low-alcohol beer brewed with low fermentation.


Adios Motherfucker

en-noun

Adios Motherfucker (plural Adios Motherfuckers)

LL-Q1860 (eng)-Flame, not lame-Adios Motherfucker.wav

Long Island iced tea
Long Island iced tea

A mixed drink variant of the Long Island iced tea.


Clit Splitter

LL-Q1860 (eng)-Flame, not lame-Clit Splitter.wav

A cocktail consisting of rum, whiskey, amaretto, and peach schnapps.


SAMA

Coordinate term: LAMA

(pharmacology) Initialism of short-acting muscarinic antagonist.


Lortab

en-proper noun

Lortab (countable and uncountable, plural Lortabs)

After my second day at the Cold Drink, I knew why Misty worked so hard: she was high every night. Lortab, Oxycontin, coke, Ecstasy, meth.

2017, Jesmyn Ward, Sing, Unburied, Sing, Bloomsbury Circus, page 32:

(pharmacology) A brand name for an analgesic combination drug containing hydrocodone and paracetamol, often used for recreational purposes.


nicotini

A martini cocktail made by mixing vodka with a tea made from tobacco leaves.


sherrify

en-verb

sherrify (third-person singular simple present sherrifies, present participle sherrifying, simple past and past participle sherrified)

sherrifies (present singular third-person)
sherrifying (participle present)
sherrified (participle past)
sherrified (past)

The other red sweet wines, however, have been unbalanced, very deficient in color, and apt to oxidize or sherrify at an early age.

1944, Maynard Andrew Amerine, Albert Julius Winkler, Composition and Quality of Musts and Wines of California Grapes (page 640)