"macroenzyme" meaning in All languages combined

{
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "macro",
        "3": "enzyme"
      },
      "expansion": "macro- + enzyme",
      "name": "prefix"
    }
  ],
  "etymology_text": "From macro- + enzyme.",
  "forms": [
    {
      "form": "macroenzymes",
      "tags": [
        "plural"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "macroenzyme (plural macroenzymes)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        {
          "kind": "other",
          "name": "English entries with incorrect language header",
          "parents": [
            "Entries with incorrect language header",
            "Entry maintenance"
          ],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "English terms prefixed with macro-",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Pages with 1 entry",
          "parents": [],
          "source": "w"
        },
        {
          "kind": "other",
          "name": "Pages with entries",
          "parents": [],
          "source": "w"
        }
      ],
      "examples": [
        {
          "ref": "1993, Galasso PJ, Litin SC, O'Brien JF, “The macroenzymes: a clinical review”, in Mayo Clinic Proceedings, volume 68, number 4, →DOI, →PMID, pages 349–354:",
          "text": "Macroenzymes are serum enzymes that have a higher molecular mass than the corresponding enzyme normally found in serum under physiologic or pathophysiologic conditions. Although no evidence convincingly indicates that macroenzymes cause disease or necessitate treatment, some patients with immunoglobulin-complexed enzyme disorders have previously been reported to have associated autoimmune diseases or malignant lesions. To address this issue, we reviewed the medical records of 42 patients in whom a macroenzyme had been detected during assessment at the Mayo Clinic between 1986 and 1990.",
          "type": "quote"
        }
      ],
      "glosses": [
        "An enzyme of macromolecular size due to unusual biopolymerization or immune complexing, such as when a normal enzyme is protein-bound, typically by immunoglobulins (antibodies); macroenzymes by themselves are not always pathophysiologic or pathogenic, but their occurrence is increased in certain diseases (their formation is encouraged by some pathogenetic processes)."
      ],
      "id": "en-macroenzyme-en-noun-w9BgBCAl",
      "links": [
        [
          "enzyme",
          "enzyme"
        ],
        [
          "macromolecular",
          "macromolecule"
        ],
        [
          "biopolymer",
          "biopolymer"
        ],
        [
          "immunoglobulin",
          "immunoglobulin"
        ],
        [
          "pathophysiologic",
          "pathophysiology"
        ],
        [
          "pathogenic",
          "pathogenic"
        ]
      ]
    }
  ],
  "word": "macroenzyme"
}

{
  "etymology_templates": [
    {
      "args": {
        "1": "en",
        "2": "macro",
        "3": "enzyme"
      },
      "expansion": "macro- + enzyme",
      "name": "prefix"
    }
  ],
  "etymology_text": "From macro- + enzyme.",
  "forms": [
    {
      "form": "macroenzymes",
      "tags": [
        "plural"
      ]
    }
  ],
  "head_templates": [
    {
      "args": {},
      "expansion": "macroenzyme (plural macroenzymes)",
      "name": "en-noun"
    }
  ],
  "lang": "English",
  "lang_code": "en",
  "pos": "noun",
  "senses": [
    {
      "categories": [
        "English countable nouns",
        "English entries with incorrect language header",
        "English lemmas",
        "English nouns",
        "English terms prefixed with macro-",
        "English terms with quotations",
        "Pages with 1 entry",
        "Pages with entries"
      ],
      "examples": [
        {
          "ref": "1993, Galasso PJ, Litin SC, O'Brien JF, “The macroenzymes: a clinical review”, in Mayo Clinic Proceedings, volume 68, number 4, →DOI, →PMID, pages 349–354:",
          "text": "Macroenzymes are serum enzymes that have a higher molecular mass than the corresponding enzyme normally found in serum under physiologic or pathophysiologic conditions. Although no evidence convincingly indicates that macroenzymes cause disease or necessitate treatment, some patients with immunoglobulin-complexed enzyme disorders have previously been reported to have associated autoimmune diseases or malignant lesions. To address this issue, we reviewed the medical records of 42 patients in whom a macroenzyme had been detected during assessment at the Mayo Clinic between 1986 and 1990.",
          "type": "quote"
        }
      ],
      "glosses": [
        "An enzyme of macromolecular size due to unusual biopolymerization or immune complexing, such as when a normal enzyme is protein-bound, typically by immunoglobulins (antibodies); macroenzymes by themselves are not always pathophysiologic or pathogenic, but their occurrence is increased in certain diseases (their formation is encouraged by some pathogenetic processes)."
      ],
      "links": [
        [
          "enzyme",
          "enzyme"
        ],
        [
          "macromolecular",
          "macromolecule"
        ],
        [
          "biopolymer",
          "biopolymer"
        ],
        [
          "immunoglobulin",
          "immunoglobulin"
        ],
        [
          "pathophysiologic",
          "pathophysiology"
        ],
        [
          "pathogenic",
          "pathogenic"
        ]
      ]
    }
  ],
  "word": "macroenzyme"
}