See isoform on Wiktionary
{ "etymology_templates": [ { "args": { "1": "en", "2": "iso-", "3": "form" }, "expansion": "iso- + form", "name": "af" } ], "etymology_text": "From iso- + form.", "forms": [ { "form": "isoforms", "tags": [ "plural" ] } ], "head_templates": [ { "args": {}, "expansion": "isoform (plural isoforms)", "name": "en-noun" } ], "lang": "English", "lang_code": "en", "pos": "noun", "senses": [ { "categories": [ { "kind": "other", "name": "English entries with incorrect language header", "parents": [ "Entries with incorrect language header", "Entry maintenance" ], "source": "w" }, { "kind": "other", "name": "English terms prefixed with iso-", "parents": [], "source": "w" }, { "kind": "other", "name": "Entries with translation boxes", "parents": [], "source": "w" }, { "kind": "other", "name": "Pages with 1 entry", "parents": [], "source": "w" }, { "kind": "other", "name": "Pages with entries", "parents": [], "source": "w" }, { "kind": "other", "name": "Terms with French translations", "parents": [], "source": "w" }, { "kind": "other", "name": "Terms with Italian translations", "parents": [], "source": "w" }, { "kind": "other", "name": "Terms with Portuguese translations", "parents": [], "source": "w" }, { "kind": "other", "name": "Terms with Spanish translations", "parents": [], "source": "w" }, { "kind": "topical", "langcode": "en", "name": "Biochemistry", "orig": "en:Biochemistry", "parents": [ "Biology", "Chemistry", "Sciences", "All topics", "Fundamental" ], "source": "w" } ], "derived": [ { "word": "subisoform" } ], "examples": [ { "ref": "1997, Louis V. Avioli, Metabolic Bone Disease and Clinically Related Disorders, page 98:", "text": "Intriguingly, the rat C1b isoform of the calcitonin receptor (CTR) (see Section VI-B) has very little interaction with the thyroidally derived form of calcitonin.", "type": "quote" }, { "ref": "2015 February 12, Emily K Mathey et al., “Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype”, in Journal of Neurology, Neurosurgery, and Psychiatry, volume 86, →DOI:", "text": "This can be demonstrated in NOD mice in which a point mutation in the autoimmune regulator (Aire) gene results in the reduced expression of P0 in the thymus and a concomitant increase of P0 specific T cells in the periphery. 107 Similarly, autoimmunity is shifted towards the peripheral nerve in another NOD model deficient for isoforms of ICAM-1. 108 Altered expression of ICAM-1 on thymic epithelial cells transforms selection of T cells from a diabetogenic into a neuritogenic repertoire. 108 Studies such as these highlight the critical role of regulatory mechanisms in maintaining immune homeostasis and the impact that changes to regulation can have on the development of disease.", "type": "quote" } ], "glosses": [ "Any of several different forms of the same protein, arising from either single nucleotide polymorphisms, differential splicing of mRNA, or post-translational modifications (e.g. sulfation, glycosylation, etc.)" ], "id": "en-isoform-en-noun-o77JELt6", "links": [ [ "biochemistry", "biochemistry" ], [ "protein", "protein" ], [ "single nucleotide polymorphism", "single nucleotide polymorphism" ], [ "mRNA", "mRNA" ], [ "sulfation", "sulfation" ], [ "glycosylation", "glycosylation" ] ], "raw_glosses": [ "(biochemistry) Any of several different forms of the same protein, arising from either single nucleotide polymorphisms, differential splicing of mRNA, or post-translational modifications (e.g. sulfation, glycosylation, etc.)" ], "related": [ { "word": "alloform" }, { "word": "glycoisoform" }, { "word": "isoformic" }, { "word": "isomer" }, { "word": "isotope" } ], "topics": [ "biochemistry", "biology", "chemistry", "microbiology", "natural-sciences", "physical-sciences" ], "translations": [ { "code": "fr", "lang": "French", "sense": "Translations", "word": "isoforme" }, { "code": "it", "lang": "Italian", "sense": "Translations", "word": "isoforma" }, { "code": "pt", "lang": "Portuguese", "sense": "Translations", "word": "isoforma" }, { "code": "es", "lang": "Spanish", "sense": "Translations", "word": "isoforma" } ] } ], "word": "isoform" }
{ "derived": [ { "word": "subisoform" } ], "etymology_templates": [ { "args": { "1": "en", "2": "iso-", "3": "form" }, "expansion": "iso- + form", "name": "af" } ], "etymology_text": "From iso- + form.", "forms": [ { "form": "isoforms", "tags": [ "plural" ] } ], "head_templates": [ { "args": {}, "expansion": "isoform (plural isoforms)", "name": "en-noun" } ], "lang": "English", "lang_code": "en", "pos": "noun", "related": [ { "word": "alloform" }, { "word": "glycoisoform" }, { "word": "isoformic" }, { "word": "isomer" }, { "word": "isotope" } ], "senses": [ { "categories": [ "English countable nouns", "English entries with incorrect language header", "English lemmas", "English nouns", "English terms prefixed with iso-", "English terms with quotations", "Entries with translation boxes", "Pages with 1 entry", "Pages with entries", "Terms with French translations", "Terms with Italian translations", "Terms with Portuguese translations", "Terms with Spanish translations", "Translation table header lacks gloss", "en:Biochemistry" ], "examples": [ { "ref": "1997, Louis V. Avioli, Metabolic Bone Disease and Clinically Related Disorders, page 98:", "text": "Intriguingly, the rat C1b isoform of the calcitonin receptor (CTR) (see Section VI-B) has very little interaction with the thyroidally derived form of calcitonin.", "type": "quote" }, { "ref": "2015 February 12, Emily K Mathey et al., “Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype”, in Journal of Neurology, Neurosurgery, and Psychiatry, volume 86, →DOI:", "text": "This can be demonstrated in NOD mice in which a point mutation in the autoimmune regulator (Aire) gene results in the reduced expression of P0 in the thymus and a concomitant increase of P0 specific T cells in the periphery. 107 Similarly, autoimmunity is shifted towards the peripheral nerve in another NOD model deficient for isoforms of ICAM-1. 108 Altered expression of ICAM-1 on thymic epithelial cells transforms selection of T cells from a diabetogenic into a neuritogenic repertoire. 108 Studies such as these highlight the critical role of regulatory mechanisms in maintaining immune homeostasis and the impact that changes to regulation can have on the development of disease.", "type": "quote" } ], "glosses": [ "Any of several different forms of the same protein, arising from either single nucleotide polymorphisms, differential splicing of mRNA, or post-translational modifications (e.g. sulfation, glycosylation, etc.)" ], "links": [ [ "biochemistry", "biochemistry" ], [ "protein", "protein" ], [ "single nucleotide polymorphism", "single nucleotide polymorphism" ], [ "mRNA", "mRNA" ], [ "sulfation", "sulfation" ], [ "glycosylation", "glycosylation" ] ], "raw_glosses": [ "(biochemistry) Any of several different forms of the same protein, arising from either single nucleotide polymorphisms, differential splicing of mRNA, or post-translational modifications (e.g. sulfation, glycosylation, etc.)" ], "topics": [ "biochemistry", "biology", "chemistry", "microbiology", "natural-sciences", "physical-sciences" ] } ], "translations": [ { "code": "fr", "lang": "French", "sense": "Translations", "word": "isoforme" }, { "code": "it", "lang": "Italian", "sense": "Translations", "word": "isoforma" }, { "code": "pt", "lang": "Portuguese", "sense": "Translations", "word": "isoforma" }, { "code": "es", "lang": "Spanish", "sense": "Translations", "word": "isoforma" } ], "word": "isoform" }
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This page is a part of the kaikki.org machine-readable All languages combined dictionary. This dictionary is based on structured data extracted on 2025-01-13 from the enwiktionary dump dated 2025-01-01 using wiktextract (4ba5975 and 4ed51a5). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.
If you use this data in academic research, please cite Tatu Ylonen: Wiktextract: Wiktionary as Machine-Readable Structured Data, Proceedings of the 13th Conference on Language Resources and Evaluation (LREC), pp. 1317-1325, Marseille, 20-25 June 2022. Linking to the relevant page(s) under https://kaikki.org would also be greatly appreciated.